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Items: 1 to 50 of 152

1.

Clinical trials in low-resource settings: the perspectives of caregivers of paediatric participants from Uganda, Tanzania and Kenya.

van den Berg M, Ogutu B, Sewankambo NK, Merten S, Biller-Andorno N, Tanner M.

Trop Med Int Health. 2019 Jun 19. doi: 10.1111/tmi.13281. [Epub ahead of print]

PMID:
31215122
2.

Care-Seeking Dynamics among Patients with Diabetes Mellitus and Hypertension in Selected Rural Settings in Kenya.

Karinja M, Pillai G, Schlienger R, Tanner M, Ogutu B.

Int J Environ Res Public Health. 2019 Jun 6;16(11). pii: E2016. doi: 10.3390/ijerph16112016.

3.

RTS,S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials.

van den Berg M, Ogutu B, Sewankambo NK, Biller-Andorno N, Tanner M.

Trials. 2019 May 31;20(1):316. doi: 10.1186/s13063-019-3391-7.

4.

The effects of aflatoxin exposure on Hepatitis B-vaccine induced immunity in Kenyan children.

Githang'a D, Wangia RN, Mureithi MW, Wandiga SO, Mutegi C, Ogutu B, Agweyu A, Wang JS, Anzala O.

Curr Probl Pediatr Adolesc Health Care. 2019 May;49(5):117-130. doi: 10.1016/j.cppeds.2019.04.005. Epub 2019 May 16.

PMID:
31103452
5.

Population pharmacokinetics and pharmacodynamics of the artesunate-mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children.

Guidi M, Mercier T, Aouri M, Decosterd LA, Csajka C, Ogutu B, Carn G, Kiechel JR.

Malar J. 2019 Apr 18;18(1):139. doi: 10.1186/s12936-019-2754-6.

6.

Correlation Between Malaria-Specific Antibody Profiles and Responses to Artemisinin Combination Therapy for Treatment of Uncomplicated Malaria in Western Kenya.

Odhiambo G, Bergmann-Leitner E, Maraka M, Wanjala CNL, Duncan E, Waitumbi J, Andagalu B, Jura WGZO, Dutta S, Angov E, Ogutu BR, Kamau E, Ochiel D.

J Infect Dis. 2019 May 24;219(12):1969-1979. doi: 10.1093/infdis/jiz027.

PMID:
30649381
7.

Malaria, mental disorders, immunity and their inter-relationships - A cross sectional study in a household population in a health and demographic surveillance site in Kenya.

Jenkins R, Ong'echa M, Othieno C, Ongeri L, Sifuna P, Omollo R, Leonard B, Ogutu B.

EBioMedicine. 2019 Jan;39:369-376. doi: 10.1016/j.ebiom.2018.11.064. Epub 2018 Dec 11.

8.

The Next Generation Scientist program: capacity-building for future scientific leaders in low- and middle-income countries.

Pillai G, Chibale K, Constable EC, Keller AN, Gutierrez MM, Mirza F, Sengstag C, Masimirembwa C, Denti P, Maartens G, Ramsay M, Ogutu B, Makonnen E, Gordon R, Ferreira CG, Goldbaum FA, Degrave WMS, Spector J, Tadmor B, Kaiser HJ.

BMC Med Educ. 2018 Oct 10;18(1):233. doi: 10.1186/s12909-018-1331-y.

9.

Females of HbAS genotype have reduced concentration of the malaria protective deoxyhemoglobin S than males.

Waitumbi JN, Kifude CM, Hunja CW, Ogutu BR.

PLoS One. 2018 Sep 11;13(9):e0203455. doi: 10.1371/journal.pone.0203455. eCollection 2018.

10.

Estimating terrestrial gross primary productivity in water limited ecosystems across Africa using the Southampton Carbon Flux (SCARF) model.

Chiwara P, Ogutu BO, Dash J, Milton EJ, Ardö J, Saunders M, Nicolini G.

Sci Total Environ. 2018 Jul 15;630:1472-1483. doi: 10.1016/j.scitotenv.2018.02.314. Epub 2018 Mar 7.

PMID:
29727926
11.

A Spatiotemporal Analysis of HIV-Associated Mortality in Rural Western Kenya 2011-2015.

Sifuna P, Otieno L, Andagalu B, Oyieko J, Ogutu B, Singoei V, Owuoth J, Ogwang S, Cowden J, Otieno W.

J Acquir Immune Defic Syndr. 2018 Aug 15;78(5):483-490. doi: 10.1097/QAI.0000000000001710.

12.

Dosing of Ceftriaxone and Metronidazole for Children With Severe Acute Malnutrition.

Standing JF, Ongas MO, Ogwang C, Kagwanja N, Murunga S, Mwaringa S, Ali R, Mturi N, Timbwa M, Manyasi C, Mwalekwa L, Bandika VL, Ogutu B, Waichungo J, Kipper K, Berkley JA; FLACSAM-PK Study Group.

Clin Pharmacol Ther. 2018 Dec;104(6):1165-1174. doi: 10.1002/cpt.1078. Epub 2018 Apr 19.

13.

Cause-specific mortality in the Kombewa health and demographic surveillance systems site, rural Western Kenya from 2011-2015.

Sifuna P, Otieno L, Ogwang S, Ogutu B, Andagalu B, Owuoth J, Singoei V, Cowden J, Otieno W.

Glob Health Action. 2018;11(1):1442959. doi: 10.1080/16549716.2018.1442959.

14.

Liquid chromatography-tandem mass spectrometry for the simultaneous quantitation of ceftriaxone, metronidazole and hydroxymetronidazole in plasma from seriously ill, severely malnourished children.

Ongas M, Standing J, Ogutu B, Waichungo J, Berkley JA, Kipper K.

Wellcome Open Res. 2017 Jun 19;2:43. doi: 10.12688/wellcomeopenres.11728.2. eCollection 2017.

15.

True malaria prevalence in children under five: Bayesian estimation using data of malaria household surveys from three sub-Saharan countries.

Mfueni E, Devleesschauwer B, Rosas-Aguirre A, Van Malderen C, Brandt PT, Ogutu B, Snow RW, Tshilolo L, Zurovac D, Vanderelst D, Speybroeck N.

Malar J. 2018 Feb 5;17(1):65. doi: 10.1186/s12936-018-2211-y.

16.

Stabilization of RDT target antigens present in dried Plasmodium falciparum-infected samples for validating malaria rapid diagnostic tests at the point of care.

Morang'a C, Ayieko C, Awinda G, Achilla R, Moseti C, Ogutu B, Waitumbi J, Wanja E.

Malar J. 2018 Jan 8;17(1):10. doi: 10.1186/s12936-017-2155-7.

17.

Longitudinal estimation of Plasmodium falciparum prevalence in relation to malaria prevention measures in six sub-Saharan African countries.

Drakeley C, Abdulla S, Agnandji ST, Fernandes JF, Kremsner P, Lell B, Mewono L, Bache BE, Mihayo MG, Juma O, Tanner M, Tahita MC, Tinto H, Diallo S, Lompo P, D'Alessandro U, Ogutu B, Otieno L, Otieno S, Otieno W, Oyieko J, Asante KP, Dery DB, Adjei G, Adeniji E, Atibilla D, Owusu-Agyei S, Greenwood B, Gesase S, Lusingu J, Mahende C, Mongi R, Segeja M, Adjei S, Agbenyega T, Agyekum A, Ansong D, Bawa JT, Boateng HO, Dandalo L, Escamilla V, Hoffman I, Maenje P, Martinson F, Carter T, Leboulleux D, Kaslow DC, Usuf E, Pirçon JY, Bahmanyar ER.

Malar J. 2017 Oct 27;16(1):433. doi: 10.1186/s12936-017-2078-3.

18.

Optimization of Maillard Reaction between Glucosamine and Other Precursors by Measuring Browning with a Spectrophotometer.

Ogutu B, Kim YJ, Kim DW, Oh SC, Hong DL, Lee YB.

Prev Nutr Food Sci. 2017 Sep;22(3):211-215. doi: 10.3746/pnf.2017.22.3.211. Epub 2017 Sep 30.

19.

Malaria and mental disorder: a population study in an area endemic for malaria in Kenya.

Jenkins R, Othieno C, Ongeri L, Ongecha M, Sifuna P, Omollo R, Ogutu B.

World Psychiatry. 2017 Oct;16(3):324-325. doi: 10.1002/wps.20473. No abstract available.

20.

Factors associated with malaria microscopy diagnostic performance following a pilot quality-assurance programme in health facilities in malaria low-transmission areas of Kenya, 2014.

Odhiambo F, Buff AM, Moranga C, Moseti CM, Wesongah JO, Lowther SA, Arvelo W, Galgalo T, Achia TO, Roka ZG, Boru W, Chepkurui L, Ogutu B, Wanja E.

Malar J. 2017 Sep 13;16(1):371. doi: 10.1186/s12936-017-2018-2.

21.

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure.

Abdi AI, Hodgson SH, Muthui MK, Kivisi CA, Kamuyu G, Kimani D, Hoffman SL, Juma E, Ogutu B, Draper SJ, Osier F, Bejon P, Marsh K, Bull PC.

BMC Infect Dis. 2017 Aug 23;17(1):585. doi: 10.1186/s12879-017-2686-0.

22.

Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Malaria.

Supan C, Mombo-Ngoma G, Kombila M, Ospina Salazar CL, Held J, Lell B, Cantalloube C, Djeriou E, Ogutu B, Waitumbi J, Otsula N, Apollo D, Polhemus ME, Kremsner PG, Walsh DS.

Am J Trop Med Hyg. 2017 Aug;97(2):514-525. doi: 10.4269/ajtmh.16-0731. Epub 2017 Jul 19.

23.

Evaluation of a laboratory quality assurance pilot programme for malaria diagnostics in low-transmission areas of Kenya, 2013.

Wanja E, Achilla R, Obare P, Adeny R, Moseti C, Otieno V, Morang'a C, Murigi E, Nyamuni J, Monthei DR, Ogutu B, Buff AM.

Malar J. 2017 May 25;16(1):221. doi: 10.1186/s12936-017-1856-2.

24.

Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria.

Nguetse CN, Adegnika AA, Agbenyega T, Ogutu BR, Krishna S, Kremsner PG, Velavan TP.

Malar J. 2017 May 23;16(1):217. doi: 10.1186/s12936-017-1868-y.

25.

Safety and efficacy of the choline analogue SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter trials in African patients.

Held J, Supan C, Salazar CLO, Tinto H, Bonkian LN, Nahum A, Sié A, Abdulla S, Cantalloube C, Djeriou E, Bouyou-Akotet M, Ogutu B, Mordmüller B, Kreidenweiss A, Siribie M, Sirima SB, Kremsner PG.

Malar J. 2017 May 4;16(1):188. doi: 10.1186/s12936-017-1832-x.

26.

Building Capability for Clinical Pharmacology Research in Sub-Saharan Africa.

Gutierrez MM, Pillai G, Felix S, Romero F, Onyango KO, Owusu-Agyei S, Asante KP, Barnes KI, Sinxadi P, Allen E, Abdulla S, Masimirembwa C, Munyoro M, Yimer G, Gebre-Mariam T, Spector J, Ogutu B.

Clin Pharmacol Ther. 2017 Nov;102(5):786-795. doi: 10.1002/cpt.695. Epub 2017 Jun 5. Review.

PMID:
28378903
27.

Open-source mobile digital platform for clinical trial data collection in low-resource settings.

van Dam J, Omondi Onyango K, Midamba B, Groosman N, Hooper N, Spector J, Pillai GC, Ogutu B.

BMJ Innov. 2017 Feb;3(1):26-31. doi: 10.1136/bmjinnov-2016-000164. Epub 2017 Jan 6.

28.

Plasma nevirapine concentrations predict virological and adherence failure in Kenyan HIV-1 infected patients with extensive antiretroviral treatment exposure.

Kimulwo MJ, Okendo J, Aman RA, Ogutu BR, Kokwaro GO, Ochieng DJ, Muigai AW, Oloo FA, Ochieng W.

PLoS One. 2017 Feb 24;12(2):e0172960. doi: 10.1371/journal.pone.0172960. eCollection 2017.

29.

Partial HIV C2V3 envelope sequence analysis reveals association of coreceptor tropism, envelope glycosylation and viral genotypic variability among Kenyan patients on HAART.

Kitawi RC, Hunja CW, Aman R, Ogutu BR, Muigai AW, Kokwaro GO, Ochieng W.

Virol J. 2017 Feb 14;14(1):29. doi: 10.1186/s12985-017-0703-y.

30.

Antimalarials: Molecular Drug Targets and Mechanism of Action.

Achieng AO, Rawat M, Ogutu B, Guyah B, Michael Ong'echa J, J Perkins D, Kempaiah P.

Curr Top Med Chem. 2017;17(19):2114-2128. doi: 10.2174/1568026617666170130115323. Review.

PMID:
28137233
31.

Using health and demographic surveillance systems for teratovigilance in Africa.

Kirakoya-Samadoulougou F, Sombié I, Ogutu B, Tinto H, Kouanda S, Tiono AB, Otieno W, Dodoo A, Kamanda M, Sankoh O.

Lancet Glob Health. 2016 Dec;4(12):e906. doi: 10.1016/S2214-109X(16)30252-2. No abstract available.

32.

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection.

Hodgson SH, Llewellyn D, Silk SE, Milne KH, Elias SC, Miura K, Kamuyu G, Juma EA, Magiri C, Muia A, Jin J, Spencer AJ, Longley RJ, Mercier T, Decosterd L, Long CA, Osier FH, Hoffman SL, Ogutu B, Hill AV, Marsh K, Draper SJ.

Front Microbiol. 2016 Oct 13;7:1604. eCollection 2016.

33.

Multi-Country Evaluation of Safety of Dihydroartemisinin/Piperaquine Post-Licensure in African Public Hospitals with Electrocardiograms.

Kabanywanyi AM, Baiden R, Ali AM, Mahende MK, Ogutu BR, Oduro A, Tinto H, Gyapong M, Sie A, Sevene E, Macete E, Owusu-Agyei S, Adjei A, Compaoré G, Valea I, Osei I, Yawson A, Adjuik M, Akparibo R, Kakolwa MA, Abdulla S, Binka F.

PLoS One. 2016 Oct 20;11(10):e0164851. doi: 10.1371/journal.pone.0164851. eCollection 2016.

34.

Field evaluation of diagnostic performance of malaria rapid diagnostic tests in western Kenya.

Wanja EW, Kuya N, Moranga C, Hickman M, Johnson JD, Moseti C, Anova L, Ogutu B, Ohrt C.

Malar J. 2016 Sep 7;15:456. doi: 10.1186/s12936-016-1508-y.

35.

Comparison of artesunate-mefloquine and artemether-lumefantrine fixed-dose combinations for treatment of uncomplicated Plasmodium falciparum malaria in children younger than 5 years in sub-Saharan Africa: a randomised, multicentre, phase 4 trial.

Sirima SB, Ogutu B, Lusingu JPA, Mtoro A, Mrango Z, Ouedraogo A, Yaro JB, Onyango KO, Gesase S, Mnkande E, Ngocho JS, Ackermann I, Aubin F, Vanraes J, Strub N, Carn G.

Lancet Infect Dis. 2016 Oct;16(10):1123-1133. doi: 10.1016/S1473-3099(16)30020-2. Epub 2016 Jul 16.

36.

Safety and immunogenicity of RTS,S/AS01 malaria vaccine in infants and children with WHO stage 1 or 2 HIV disease: a randomised, double-blind, controlled trial.

Otieno L, Oneko M, Otieno W, Abuodha J, Owino E, Odero C, Mendoza YG, Andagalu B, Awino N, Ivinson K, Heerwegh D, Otsyula N, Oziemkowska M, Usuf EA, Otieno A, Otieno K, Leboulleux D, Leach A, Oyieko J, Slutsker L, Lievens M, Cowden J, Lapierre D, Kariuki S, Ogutu B, Vekemans J, Hamel MJ.

Lancet Infect Dis. 2016 Oct;16(10):1134-1144. doi: 10.1016/S1473-3099(16)30161-X. Epub 2016 Jul 7.

PMID:
27394191
37.

Glucose-6-phosphate dehydrogenase deficiency and reduced haemoglobin levels in African children with severe malaria.

Nguetse CN, Meyer CG, Adegnika AA, Agbenyega T, Ogutu BR, Kremsner PG, Velavan TP.

Malar J. 2016 Jul 7;15(1):346. doi: 10.1186/s12936-016-1396-1.

38.

Erratum to: Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions - a prospective multicenter cohort study.

Schmutzhard J, Lackner P, Helbok R, Hurth HV, Aregger FC, Muigg V, Kegele J, Bunk S, Oberhammer L, Fischer N, Pinggera L, Otieno A, Ogutu B, Agbenyega T, Ansong D, Adegnika AA, Issifou S, Zorowka P, Krishna S, Mordmüller B, Schmutzhard E, Kremsner P.

BMC Med. 2016 Apr 22;14:70. doi: 10.1186/s12916-016-0616-4. No abstract available.

39.

Adenovirus type 35-vectored tuberculosis vaccine has an acceptable safety and tolerability profile in healthy, BCG-vaccinated, QuantiFERON(®)-TB Gold (+) Kenyan adults without evidence of tuberculosis.

Walsh DS, Owira V, Polhemus M, Otieno L, Andagalu B, Ogutu B, Waitumbi J, Hawkridge A, Shepherd B, Pau MG, Sadoff J, Douoguih M, McClain JB; Aeras C-012-402 Study Team.

Vaccine. 2016 May 5;34(21):2430-2436. doi: 10.1016/j.vaccine.2016.03.069. Epub 2016 Mar 26.

40.

Seeking treatment for uncomplicated malaria: experiences from the Kintampo districts of Ghana.

Febir LG, Asante KP, Afari-Asiedu S, Abokyi LN, Kwarteng A, Ogutu B, Gyapong M, Owusu-Agyei S.

Malar J. 2016 Feb 20;15:108. doi: 10.1186/s12936-016-1151-7.

41.

Treatment outcomes in a safety observational study of dihydroartemisinin/piperaquine (Eurartesim(®)) in the treatment of uncomplicated malaria at public health facilities in four African countries.

Adjei A, Narh-Bana S, Amu A, Kukula V, Nagai RA, Owusu-Agyei S, Oduro A, Macete E, Abdulla S, Halidou T, Sie A, Osei I, Sevene E, Asante KP, Mulokozi A, Compaore G, Valea I, Adjuik M, Baiden R, Ogutu B, Binka F, Gyapong M.

Malar J. 2016 Jan 27;15:43. doi: 10.1186/s12936-016-1099-7.

42.

Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial.

Kremsner PG, Adegnika AA, Hounkpatin AB, Zinsou JF, Taylor TE, Chimalizeni Y, Liomba A, Kombila M, Bouyou-Akotet MK, Mawili Mboumba DP, Agbenyega T, Ansong D, Sylverken J, Ogutu BR, Otieno GA, Wangwe A, Bojang KA, Okomo U, Sanya-Isijola F, Newton CR, Njuguna P, Kazungu M, Kerb R, Geditz M, Schwab M, Velavan TP, Nguetse C, Köhler C, Issifou S, Bolte S, Engleitner T, Mordmüller B, Krishna S.

PLoS Med. 2016 Jan 12;13(1):e1001938. doi: 10.1371/journal.pmed.1001938. eCollection 2016 Jan.

43.

Development, characterization and antimalarial efficacy of dihydroartemisinin loaded solid lipid nanoparticles.

Omwoyo WN, Melariri P, Gathirwa JW, Oloo F, Mahanga GM, Kalombo L, Ogutu B, Swai H.

Nanomedicine. 2016 Apr;12(3):801-809. doi: 10.1016/j.nano.2015.11.017. Epub 2015 Dec 24.

PMID:
26724538
44.

Common mental disorder in Nyanza province, Kenya in 2013 and its associated risk factors--an assessment of change since 2004, using a repeat household survey in a demographic surveillance site.

Jenkins R, Othieno C, Ongeri L, Sifuna P, Ongecha M, Kingora J, Kiima D, Omollo R, Ogutu B.

BMC Psychiatry. 2015 Dec 9;15:309. doi: 10.1186/s12888-015-0693-5.

45.

A Multinational Trial of Prasugrel for Sickle Cell Vaso-Occlusive Events.

Heeney MM, Hoppe CC, Abboud MR, Inusa B, Kanter J, Ogutu B, Brown PB, Heath LE, Jakubowski JA, Zhou C, Zamoryakhin D, Agbenyega T, Colombatti R, Hassab HM, Nduba VN, Oyieko JN, Robitaille N, Segbefia CI, Rees DC; DOVE Investigators.

N Engl J Med. 2016 Feb 18;374(7):625-35. doi: 10.1056/NEJMoa1512021. Epub 2015 Dec 8.

46.

Use of Antimalarial in the Management of Fever during a Community Survey in the Kintampo Districts of Ghana.

Abokyi LN, Asante KP, Mahama E, Gyaase S, Sulemana A, Kwarteng A, Ayaam J, Dosoo D, Adu-Gyasi D, Amenga Etego S, Ogutu B, Akweongo P, Owusu-Agyei S.

PLoS One. 2015 Nov 18;10(11):e0142106. doi: 10.1371/journal.pone.0142106. eCollection 2015.

47.

Probable Post Traumatic Stress Disorder in Kenya and Its Associated Risk Factors: A Cross-Sectional Household Survey.

Jenkins R, Othieno C, Omollo R, Ongeri L, Sifuna P, Mboroki JK, Kiima D, Ogutu B.

Int J Environ Res Public Health. 2015 Oct 26;12(10):13494-509. doi: 10.3390/ijerph121013494.

48.

Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine.

Neafsey DE, Juraska M, Bedford T, Benkeser D, Valim C, Griggs A, Lievens M, Abdulla S, Adjei S, Agbenyega T, Agnandji ST, Aide P, Anderson S, Ansong D, Aponte JJ, Asante KP, Bejon P, Birkett AJ, Bruls M, Connolly KM, D'Alessandro U, Dobaño C, Gesase S, Greenwood B, Grimsby J, Tinto H, Hamel MJ, Hoffman I, Kamthunzi P, Kariuki S, Kremsner PG, Leach A, Lell B, Lennon NJ, Lusingu J, Marsh K, Martinson F, Molel JT, Moss EL, Njuguna P, Ockenhouse CF, Ogutu BR, Otieno W, Otieno L, Otieno K, Owusu-Agyei S, Park DJ, Pellé K, Robbins D, Russ C, Ryan EM, Sacarlal J, Sogoloff B, Sorgho H, Tanner M, Theander T, Valea I, Volkman SK, Yu Q, Lapierre D, Birren BW, Gilbert PB, Wirth DF.

N Engl J Med. 2015 Nov 19;373(21):2025-2037. doi: 10.1056/NEJMoa1505819. Epub 2015 Oct 21.

49.

Feasibility and cost of using mobile phones for capturing drug safety information in peri-urban settlement in Ghana: a prospective cohort study of patients with uncomplicated malaria.

Kukula VA, Dodoo AA, Akpakli J, Narh-Bana SA, Clerk C, Adjei A, Awini E, Manye S, Nagai RA, Odonkor G, Nikoi C, Adjuik M, Akweongo P, Baiden R, Ogutu B, Binka F, Gyapong M.

Malar J. 2015 Oct 19;14:411. doi: 10.1186/s12936-015-0932-8.

50.

Alcohol consumption and hazardous drinking in western Kenya--a household survey in a health and demographic surveillance site.

Jenkins R, Othieno C, Ongeri L, Kiima D, Sifuna P, Kingora J, Omollo R, Ogutu B.

BMC Psychiatry. 2015 Sep 25;15:230. doi: 10.1186/s12888-015-0603-x.

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