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Altered monocyte response to the dengue virus in those with varying severity of past dengue infection.

Kamaladasa A, Gomes L, Wijesinghe A, Jeewandara C, Toh YX, Jayathilaka D, Ogg GS, Fink K, Malavige GN.

Antiviral Res. 2019 Sep;169:104554. doi: 10.1016/j.antiviral.2019.104554. Epub 2019 Jul 6.


Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β.

Schwartz C, Moran T, Saunders SP, Kaszlikowska A, Floudas A, Bom J, Nunez G, Iwakura Y, O'Neill L, Irvine AD, McKenzie ANJ, Ogg G, Walsh PT, Demengeot J, Fallon PG.

Allergy. 2019 Apr 2. doi: 10.1111/all.13801. [Epub ahead of print]


Fevipiprant, a selective prostaglandin D2 receptor 2 antagonist, inhibits human group 2 innate lymphoid cell aggregation and function.

Hardman C, Chen W, Luo J, Batty P, Chen YL, Nahler J, Wu Y, Pavord ID, Erpenbeck VJ, Sandham DA, Xue L, Ogg G.

J Allergy Clin Immunol. 2019 Jun;143(6):2329-2333. doi: 10.1016/j.jaci.2019.02.015. Epub 2019 Feb 28. No abstract available.


Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection.

Jayathilaka D, Gomes L, Jeewandara C, Jayarathna GSB, Herath D, Perera PA, Fernando S, Wijewickrama A, Hardman CS, Ogg GS, Malavige GN.

Nat Commun. 2018 Dec 7;9(1):5242. doi: 10.1038/s41467-018-07667-z.


Correction: Synergistic activation of pro-inflammatory type-2 CD8 + T lymphocytes by lipid mediators in severe eosinophilic asthma.

Hilvering B, Hinks TSC, Stöger L, Marchi E, Salimi M, Shrimanker R, Liu W, Chen W, Luo J, Go S, Powell T, Cane J, Thulborn S, Kurioka A, Leng T, Matthews J, Connolly C, Borg C, Bafadhel M, Willberg CB, Ramasamy A, Djukanović R, Ogg G, Pavord ID, Klenerman P, Xue L.

Mucosal Immunol. 2019 Mar;12(2):581. doi: 10.1038/s41385-018-0121-5.


Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infection.

Wijeratne DT, Fernando S, Gomes L, Jeewandara C, Ginneliya A, Samarasekara S, Wijewickrama A, Hardman CS, Ogg GS, Malavige GN.

PLoS Negl Trop Dis. 2018 Oct 1;12(10):e0006540. doi: 10.1371/journal.pntd.0006540. eCollection 2018 Oct.


Foxp3+ T reg cells control psoriasiform inflammation by restraining an IFN-I-driven CD8+ T cell response.

Stockenhuber K, Hegazy AN, West NR, Ilott NE, Stockenhuber A, Bullers SJ, Thornton EE, Arnold IC, Tucci A, Waldmann H, Ogg GS, Powrie F.

J Exp Med. 2018 Aug 6;215(8):1987-1998. doi: 10.1084/jem.20172094. Epub 2018 Jul 6.


Cultured ELISpot Assay to Investigate Dengue Virus Specific T-Cell Responses.

Jeewandara C, Ogg GS, Malavige GN.

Methods Mol Biol. 2018;1808:165-171. doi: 10.1007/978-1-4939-8567-8_14.


Synergistic activation of pro-inflammatory type-2 CD8+ T lymphocytes by lipid mediators in severe eosinophilic asthma.

Hilvering B, Hinks TSC, Stöger L, Marchi E, Salimi M, Shrimanker R, Liu W, Chen W, Luo J, Go S, Powell T, Cane J, Thulborn S, Kurioka A, Leng T, Matthews J, Connolly C, Borg C, Bafadhel M, Willberg CB, Ramasamy A, Djukanović R, Ogg G, Pavord ID, Klenerman P, Xue L.

Mucosal Immunol. 2018 Sep;11(5):1408-1419. doi: 10.1038/s41385-018-0049-9. Epub 2018 Jun 15. Erratum in: Mucosal Immunol. 2018 Dec 5;:.


Killer T cells show their kinder side.

Klenerman P, Ogg G.

Nature. 2018 Mar 29;555(7698):594-595. doi: 10.1038/d41586-018-03510-z. No abstract available.


Activated innate lymphoid cell populations accumulate in human tumour tissues.

Salimi M, Wang R, Yao X, Li X, Wang X, Hu Y, Chang X, Fan P, Dong T, Ogg G.

BMC Cancer. 2018 Mar 27;18(1):341. doi: 10.1186/s12885-018-4262-4.


Orchestrated control of filaggrin-actin scaffolds underpins cornification.

Gutowska-Owsiak D, de La Serna JB, Fritzsche M, Naeem A, Podobas EI, Leeming M, Colin-York H, O'Shaughnessy R, Eggeling C, Ogg GS.

Cell Death Dis. 2018 Apr 1;9(4):412. doi: 10.1038/s41419-018-0407-2.


A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection.

Malavige GN, Wijewickrama A, Fernando S, Jeewandara C, Ginneliya A, Samarasekara S, Madushanka P, Punchihewa C, Paranavitane S, Idampitiya D, Wanigatunga C, Dissanayake H, Prathapan S, Gomes L, Aman SAB, John AS, Ogg GS.

Sci Rep. 2018 Mar 1;8(1):3857. doi: 10.1038/s41598-018-22285-x.


CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.

Hardman CS, Chen YL, Salimi M, Jarrett R, Johnson D, Järvinen VJ, Owens RJ, Repapi E, Cousins DJ, Barlow JL, McKenzie ANJ, Ogg G.

Sci Immunol. 2017 Dec 22;2(18). pii: eaan5918. doi: 10.1126/sciimmunol.aan5918.


Therapeutic vaccines for allergic disease.

Gutowska-Owsiak D, Ogg GS.

NPJ Vaccines. 2017 May 8;2:12. doi: 10.1038/s41541-017-0014-8. eCollection 2017.


Regulatory T-cells in acute dengue viral infection.

Jayaratne HE, Wijeratne D, Fernando S, Kamaladasa A, Gomes L, Wijewickrama A, Ogg GS, Malavige GN.

Immunology. 2018 May;154(1):89-97. doi: 10.1111/imm.12863. Epub 2017 Dec 18.


Emerging roles of innate lymphoid cells in inflammatory diseases: Clinical implications.

Kortekaas Krohn I, Shikhagaie MM, Golebski K, Bernink JH, Breynaert C, Creyns B, Diamant Z, Fokkens WJ, Gevaert P, Hellings P, Hendriks RW, Klimek L, Mjösberg J, Morita H, Ogg GS, O'Mahony L, Schwarze J, Seys SF, Shamji MH, Bal SM.

Allergy. 2018 Apr;73(4):837-850. doi: 10.1111/all.13340. Epub 2017 Nov 22. Review.


IL-17 Receptor A Maintains and Protects the Skin Barrier To Prevent Allergic Skin Inflammation.

Floudas A, Saunders SP, Moran T, Schwartz C, Hams E, Fitzgerald DC, Johnston JA, Ogg GS, McKenzie AN, Walsh PT, Fallon PG.

J Immunol. 2017 Jul 15;199(2):707-717. doi: 10.4049/jimmunol.1602185. Epub 2017 Jun 14.


Deficiency of filaggrin regulates endogenous cysteine protease activity, leading to impaired skin barrier function.

Wang XW, Wang JJ, Gutowska-Owsiak D, Salimi M, Selvakumar TA, Gwela A, Chen LY, Wang YJ, Giannoulatou E, Ogg G.

Clin Exp Dermatol. 2017 Aug;42(6):622-631. doi: 10.1111/ced.13113. Epub 2017 May 29.


Pathogenesis of vascular leak in dengue virus infection.

Malavige GN, Ogg GS.

Immunology. 2017 Jul;151(3):261-269. doi: 10.1111/imm.12748. Epub 2017 May 24. Review.


Secretory phospholipase A2 in the pathogenesis of acute dengue infection.

Jeewandara C, Gomes L, Udari S, Paranavitane SA, Shyamali NL, Ogg GS, Malavige GN.

Immun Inflamm Dis. 2016 Dec 11;5(1):7-15. doi: 10.1002/iid3.135. eCollection 2017 Mar.


Cysteinyl leukotriene E4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D2 and epithelial cytokines.

Salimi M, Stöger L, Liu W, Go S, Pavord I, Klenerman P, Ogg G, Xue L.

J Allergy Clin Immunol. 2017 Oct;140(4):1090-1100.e11. doi: 10.1016/j.jaci.2016.12.958. Epub 2017 Jan 20.


Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a.

Cheung KL, Jarrett R, Subramaniam S, Salimi M, Gutowska-Owsiak D, Chen YL, Hardman C, Xue L, Cerundolo V, Ogg G.

J Exp Med. 2016 Oct 17;213(11):2399-2412. Epub 2016 Sep 26.


Interleukin-33, friend and foe in type-2 immune responses.

Hardman C, Ogg G.

Curr Opin Immunol. 2016 Oct;42:16-24. doi: 10.1016/j.coi.2016.05.004. Epub 2016 May 24. Review.


Lipid-specific T cells and the skin.

Jarrett R, Ogg G.

Br J Dermatol. 2016 Oct;175 Suppl 2:19-25. doi: 10.1111/bjd.14908. Review.


Lipopolysaccharide acts synergistically with the dengue virus to induce monocyte production of platelet activating factor and other inflammatory mediators.

Kamaladasa A, Gomes L, Jeewandara C, Shyamali NL, Ogg GS, Malavige GN.

Antiviral Res. 2016 Sep;133:183-90. doi: 10.1016/j.antiviral.2016.07.016. Epub 2016 Jul 28.


Patterns and causes of liver involvement in acute dengue infection.

Fernando S, Wijewickrama A, Gomes L, Punchihewa CT, Madusanka SD, Dissanayake H, Jeewandara C, Peiris H, Ogg GS, Malavige GN.

BMC Infect Dis. 2016 Jul 8;16:319. doi: 10.1186/s12879-016-1656-2.


Expansion of highly activated invariant natural killer T cells with altered phenotype in acute dengue infection.

Kamaladasa A, Wickramasinghe N, Adikari TN, Gomes L, Shyamali NL, Salio M, Cerundolo V, Ogg GS, Malavige GN.

Clin Exp Immunol. 2016 Aug;185(2):228-38. doi: 10.1111/cei.12778.


Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase.

Jarrett R, Salio M, Lloyd-Lavery A, Subramaniam S, Bourgeois E, Archer C, Cheung KL, Hardman C, Chandler D, Salimi M, Gutowska-Owsiak D, de la Serna JB, Fallon PG, Jolin H, Mckenzie A, Dziembowski A, Podobas EI, Bal W, Johnson D, Moody DB, Cerundolo V, Ogg G.

Sci Transl Med. 2016 Feb 10;8(325):325ra18. doi: 10.1126/scitranslmed.aad6833.


Enhanced isolation of lymphoid cells from human skin.

Salimi M, Subramaniam S, Selvakumar T, Wang X, Zemenides S, Johnson D, Ogg G.

Clin Exp Dermatol. 2016 Jul;41(5):552-6. doi: 10.1111/ced.12802. Epub 2016 Jan 25.


Change in Dengue and Japanese Encephalitis Seroprevalence Rates in Sri Lanka.

Jeewandara C, Gomes L, Paranavitane SA, Tantirimudalige M, Panapitiya SS, Jayewardene A, Fernando S, Fernando RH, Prathapan S, Ogg GS, Malavige GN.

PLoS One. 2015 Dec 22;10(12):e0144799. doi: 10.1371/journal.pone.0144799. eCollection 2015.


Dengue NS1 antigen contributes to disease severity by inducing interleukin (IL)-10 by monocytes.

Adikari TN, Gomes L, Wickramasinghe N, Salimi M, Wijesiriwardana N, Kamaladasa A, Shyamali NL, Ogg GS, Malavige GN.

Clin Exp Immunol. 2016 Apr;184(1):90-100. doi: 10.1111/cei.12747. Epub 2016 Jan 19.


Role of skin homing T cells in acute dengue infection.

Malavige GN, Ogg GS.

Ann Transl Med. 2015 Oct;3(17):252. doi: 10.3978/j.issn.2305-5839.2015.09.12. No abstract available.


Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production.

Salimi M, Xue L, Jolin H, Hardman C, Cousins DJ, McKenzie AN, Ogg GS.

J Immunol. 2016 Jan 1;196(1):45-54. doi: 10.4049/jimmunol.1501102. Epub 2015 Nov 18.


Elevated and cross-responsive CD1a-reactive T cells in bee and wasp venom allergic individuals.

Subramaniam S, Aslam A, Misbah SA, Salio M, Cerundolo V, Moody DB, Ogg G.

Eur J Immunol. 2016 Jan;46(1):242-52. doi: 10.1002/eji.201545869. Epub 2015 Nov 17.


Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity.

Saunders SP, Moran T, Floudas A, Wurlod F, Kaszlikowska A, Salimi M, Quinn EM, Oliphant CJ, Núñez G, McManus R, Hams E, Irvine AD, McKenzie AN, Ogg GS, Fallon PG.

J Allergy Clin Immunol. 2016 Feb;137(2):482-91. doi: 10.1016/j.jaci.2015.06.045. Epub 2015 Aug 20.


Functionality of dengue virus specific memory T cell responses in individuals who were hospitalized or who had mild or subclinical dengue infection.

Jeewandara C, Adikari TN, Gomes L, Fernando S, Fernando RH, Perera MK, Ariyaratne D, Kamaladasa A, Salimi M, Prathapan S, Ogg GS, Malavige GN.

PLoS Negl Trop Dis. 2015 Apr 13;9(4):e0003673. doi: 10.1371/journal.pntd.0003673. eCollection 2015 Apr.


The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging.

Vukmanovic-Stejic M, Sandhu D, Seidel JA, Patel N, Sobande TO, Agius E, Jackson SE, Fuentes-Duculan J, Suárez-Fariñas M, Mabbott NA, Lacy KE, Ogg G, Nestle FO, Krueger JG, Rustin MHA, Akbar AN.

J Invest Dermatol. 2015 Jul;135(7):1752-1762. doi: 10.1038/jid.2015.63. Epub 2015 Mar 3.


Platelet activating factor contributes to vascular leak in acute dengue infection.

Jeewandara C, Gomes L, Wickramasinghe N, Gutowska-Owsiak D, Waithe D, Paranavitane SA, Shyamali NL, Ogg GS, Malavige GN.

PLoS Negl Trop Dis. 2015 Feb 3;9(2):e0003459. doi: 10.1371/journal.pntd.0003459. eCollection 2015 Feb.


Bee venom processes human skin lipids for presentation by CD1a.

Bourgeois EA, Subramaniam S, Cheng TY, De Jong A, Layre E, Ly D, Salimi M, Legaspi A, Modlin RL, Salio M, Cerundolo V, Moody DB, Ogg G.

J Exp Med. 2015 Feb 9;212(2):149-63. doi: 10.1084/jem.20141505. Epub 2015 Jan 12.


Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk.

Xue L, Fergusson J, Salimi M, Panse I, Ussher JE, Hegazy AN, Vinall SL, Jackson DG, Hunter MG, Pettipher R, Ogg G, Klenerman P.

J Allergy Clin Immunol. 2015 May;135(5):1358-66.e1-11. doi: 10.1016/j.jaci.2014.09.006. Epub 2014 Oct 19.


Innate lymphoid cells and the skin.

Salimi M, Ogg G.

BMC Dermatol. 2014 Nov 26;14:18. doi: 10.1186/1471-5945-14-18. Review.


Sphingosine 1-phosphate in acute dengue infection.

Gomes L, Fernando S, Fernando RH, Wickramasinghe N, Shyamali NL, Ogg GS, Malavige GN.

PLoS One. 2014 Nov 19;9(11):e113394. doi: 10.1371/journal.pone.0113394. eCollection 2014.


Dengue NS1 antigen as a marker of severe clinical disease.

Paranavitane SA, Gomes L, Kamaladasa A, Adikari TN, Wickramasinghe N, Jeewandara C, Shyamali NL, Ogg GS, Malavige GN.

BMC Infect Dis. 2014 Oct 31;14:570. doi: 10.1186/s12879-014-0570-8.


Histamine exerts multiple effects on expression of genes associated with epidermal barrier function.

Gutowska-Owsiak D, Salimi M, Selvakumar TA, Wang X, Taylor S, Ogg GS.

J Investig Allergol Clin Immunol. 2014;24(4):231-9.


MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion.

Oliphant CJ, Hwang YY, Walker JA, Salimi M, Wong SH, Brewer JM, Englezakis A, Barlow JL, Hams E, Scanlon ST, Ogg GS, Fallon PG, McKenzie AN.

Immunity. 2014 Aug 21;41(2):283-95. doi: 10.1016/j.immuni.2014.06.016. Epub 2014 Jul 31.


The histamine-synthesizing enzyme histidine decarboxylase is upregulated by keratinocytes in atopic skin.

Gutowska-Owsiak D, Greenwald L, Watson C, Selvakumar TA, Wang X, Ogg GS.

Br J Dermatol. 2014 Oct;171(4):771-8. doi: 10.1111/bjd.13199. Epub 2014 Sep 30.


Filaggrin-insufficiency in keratinocytes influences responsiveness of allergen-specific T cells to cognate antigen and compounds barrier function deficiency.

Marwah I, Wang X, Chan H, Ogg GS, Gutowska-Owsiak D.

Clin Immunol. 2014 Jul;153(1):153-5. doi: 10.1016/j.clim.2014.04.011. Epub 2014 Apr 29. No abstract available.


Histamine enhances keratinocyte-mediated resolution of inflammation by promoting wound healing and response to infection.

Gutowska-Owsiak D, Selvakumar TA, Salimi M, Taylor S, Ogg GS.

Clin Exp Dermatol. 2014 Mar;39(2):187-95. doi: 10.1111/ced.12256. Epub 2014 Jan 23.


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