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Items: 18

1.

A structurally derived model of subunit-dependent NMDA receptor function.

Gibb AJ, Ogden KK, McDaniel MJ, Vance KM, Kell SA, Butch C, Burger P, Liotta DC, Traynelis SF.

J Physiol. 2018 Sep;596(17):4057-4089. doi: 10.1113/JP276093. Epub 2018 Aug 1.

2.

Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology.

Ogden KK, Chen W, Swanger SA, McDaniel MJ, Fan LZ, Hu C, Tankovic A, Kusumoto H, Kosobucki GJ, Schulien AJ, Su Z, Pecha J, Bhattacharya S, Petrovski S, Cohen AE, Aizenman E, Traynelis SF, Yuan H.

PLoS Genet. 2017 Jan 17;13(1):e1006536. doi: 10.1371/journal.pgen.1006536. eCollection 2017 Jan.

3.

GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity.

Perszyk RE, DiRaddo JO, Strong KL, Low CM, Ogden KK, Khatri A, Vargish GA, Pelkey KA, Tricoire L, Liotta DC, Smith Y, McBain CJ, Traynelis SF.

Mol Pharmacol. 2016 Dec;90(6):689-702. Epub 2016 Sep 13.

4.

Prioritizing the development of mouse models for childhood brain disorders.

Ogden KK, Ozkan ED, Rumbaugh G.

Neuropharmacology. 2016 Jan;100:2-16. doi: 10.1016/j.neuropharm.2015.07.029. Epub 2015 Jul 29. Review.

5.

Correction to Synthesis and Structure Activity Relationship of Tetrahydroisoquinoline-Based Potentiators of GluN2C and GluN2D Containing N-Methyl-d-aspartate Receptors.

Santangelo Freel RM, Ogden KK, Strong KL, Khatri A, Chepiga KM, Jensen HS, Traynelis SF, Liotta DC.

J Med Chem. 2014 Jun 12;57(11):4975. doi: 10.1021/jm500710w. Epub 2014 May 30. No abstract available.

6.

Distinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors.

Hansen KB, Ogden KK, Yuan H, Traynelis SF.

Neuron. 2014 Mar 5;81(5):1084-1096. doi: 10.1016/j.neuron.2014.01.035.

7.

Potentiation of GluN2C/D NMDA receptor subtypes in the amygdala facilitates the retention of fear and extinction learning in mice.

Ogden KK, Khatri A, Traynelis SF, Heldt SA.

Neuropsychopharmacology. 2014 Feb;39(3):625-37. doi: 10.1038/npp.2013.241. Epub 2013 Sep 6.

8.

Synthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptors.

Santangelo Freel RM, Ogden KK, Strong KL, Khatri A, Chepiga KM, Jensen HS, Traynelis SF, Liotta DC.

J Med Chem. 2013 Jul 11;56(13):5351-81. doi: 10.1021/jm400177t. Epub 2013 Jun 20. Erratum in: J Med Chem. 2014 Jun 12;57(11):4975.

9.

Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors.

Hansen KB, Tajima N, Risgaard R, Perszyk RE, Jørgensen L, Vance KM, Ogden KK, Clausen RP, Furukawa H, Traynelis SF.

Mol Pharmacol. 2013 Jul;84(1):114-27. doi: 10.1124/mol.113.085803. Epub 2013 Apr 26.

10.

Contribution of the M1 transmembrane helix and pre-M1 region to positive allosteric modulation and gating of N-methyl-D-aspartate receptors.

Ogden KK, Traynelis SF.

Mol Pharmacol. 2013 May;83(5):1045-56. doi: 10.1124/mol.113.085209. Epub 2013 Mar 1.

11.

Subunit-selective allosteric inhibition of glycine binding to NMDA receptors.

Hansen KB, Ogden KK, Traynelis SF.

J Neurosci. 2012 May 2;32(18):6197-208. doi: 10.1523/JNEUROSCI.5757-11.2012.

12.

New advances in NMDA receptor pharmacology.

Ogden KK, Traynelis SF.

Trends Pharmacol Sci. 2011 Dec;32(12):726-33. doi: 10.1016/j.tips.2011.08.003. Epub 2011 Oct 11. Review.

13.

Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators.

Acker TM, Yuan H, Hansen KB, Vance KM, Ogden KK, Jensen HS, Burger PB, Mullasseril P, Snyder JP, Liotta DC, Traynelis SF.

Mol Pharmacol. 2011 Nov;80(5):782-95. doi: 10.1124/mol.111.073239. Epub 2011 Aug 1.

14.

A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.

Mullasseril P, Hansen KB, Vance KM, Ogden KK, Yuan H, Kurtkaya NL, Santangelo R, Orr AG, Le P, Vellano KM, Liotta DC, Traynelis SF.

Nat Commun. 2010 Oct 5;1:90. doi: 10.1038/ncomms1085.

15.

Glutamate receptor ion channels: structure, regulation, and function.

Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R.

Pharmacol Rev. 2010 Sep;62(3):405-96. doi: 10.1124/pr.109.002451. Review. Erratum in: Pharmacol Rev. 2014 Oct;66(4):1141.

16.

Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.

Hansen KB, Mullasseril P, Dawit S, Kurtkaya NL, Yuan H, Vance KM, Orr AG, Kvist T, Ogden KK, Le P, Vellano KM, Lewis I, Kurtkaya S, Du Y, Qui M, Murphy TJ, Snyder JP, Bräuner-Osborne H, Traynelis SF.

J Pharmacol Exp Ther. 2010 Jun;333(3):650-62. doi: 10.1124/jpet.110.166256. Epub 2010 Mar 2.

17.

Control of NMDA receptor function by the NR2 subunit amino-terminal domain.

Yuan H, Hansen KB, Vance KM, Ogden KK, Traynelis SF.

J Neurosci. 2009 Sep 30;29(39):12045-58. doi: 10.1523/JNEUROSCI.1365-09.2009.

18.

The cytochrome p450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta.

Ogden KK, Falck JR, Watts SW.

J Pharmacol Exp Ther. 2007 Nov;323(2):606-13. Epub 2007 Aug 8.

PMID:
17687070

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