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Items: 9

1.

CYP2D6 genotypes, endoxifen levels, and disease recurrence in 224 Filipino and Vietnamese women receiving adjuvant tamoxifen for operable breast cancer.

Love RR, Desta Z, Flockhart D, Skaar T, Ogburn ET, Ramamoorthy A, Uy GB, Laudico AV, Van Dinh N, Quang le H, Van To T, Young GS, Hade E, Jarjoura D.

Springerplus. 2013 Dec;2(1):52. doi: 10.1186/2193-1801-2-52. Epub 2013 Feb 15.

2.

Stereoselective and regiospecific hydroxylation of ketamine and norketamine.

Desta Z, Moaddel R, Ogburn ET, Xu C, Ramamoorthy A, Venkata SL, Sanghvi M, Goldberg ME, Torjman MC, Wainer IW.

Xenobiotica. 2012 Nov;42(11):1076-87. doi: 10.3109/00498254.2012.685777. Epub 2012 May 21.

3.

Compartment-specific gene regulation of the CAR inducer efavirenz in vivo.

Meyer zu Schwabedissen HE, Oswald S, Bresser C, Nassif A, Modess C, Desta Z, Ogburn ET, Marinova M, Lütjohann D, Spielhagen C, Nauck M, Kroemer HK, Siegmund W.

Clin Pharmacol Ther. 2012 Jul;92(1):103-11. doi: 10.1038/clpt.2012.34. Epub 2012 May 16. Erratum in: Clin Pharmacol Ther. 2013 Jan;93(1):129. Dosage error in article text.

4.

Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers.

Oswald S, Meyer zu Schwabedissen HE, Nassif A, Modess C, Desta Z, Ogburn ET, Mostertz J, Keiser M, Jia J, Hubeny A, Ulrich A, Runge D, Marinova M, Lütjohann D, Kroemer HK, Siegmund W.

Clin Pharmacol Ther. 2012 Mar;91(3):506-13. doi: 10.1038/clpt.2011.255. Epub 2012 Feb 1.

5.
6.

Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: a multicenter study.

Irvin WJ Jr, Walko CM, Weck KE, Ibrahim JG, Chiu WK, Dees EC, Moore SG, Olajide OA, Graham ML, Canale ST, Raab RE, Corso SW, Peppercorn JM, Anderson SM, Friedman KJ, Ogburn ET, Desta Z, Flockhart DA, McLeod HL, Evans JP, Carey LA.

J Clin Oncol. 2011 Aug 20;29(24):3232-9. doi: 10.1200/JCO.2010.31.4427. Epub 2011 Jul 18.

7.

Microfabricated electrochemical detector for high-performance liquid chromatography.

Ogburn ET, Dziewatkoski M, Moles D, Johnson JM, Heineman WR.

Anal Chem. 2011 Sep 15;83(18):6963-70. doi: 10.1021/ac200476j. Epub 2011 Aug 18.

PMID:
21598939
8.

Contribution of N-glucuronidation to efavirenz elimination in vivo in the basal and rifampin-induced metabolism of efavirenz.

Cho DY, Ogburn ET, Jones D, Desta Z.

Antimicrob Agents Chemother. 2011 Apr;55(4):1504-9. doi: 10.1128/AAC.00883-10. Epub 2011 Jan 31.

9.

Efavirenz primary and secondary metabolism in vitro and in vivo: identification of novel metabolic pathways and cytochrome P450 2A6 as the principal catalyst of efavirenz 7-hydroxylation.

Ogburn ET, Jones DR, Masters AR, Xu C, Guo Y, Desta Z.

Drug Metab Dispos. 2010 Jul;38(7):1218-29. doi: 10.1124/dmd.109.031393. Epub 2010 Mar 24.

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