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Items: 1 to 50 of 51

1.

Design, Synthesis, and Evaluation of 18F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes.

Chen Z, Mori W, Fu H, Schafroth MA, Hatori A, Shao T, Zhang G, Van RS, Zhang Y, Hu K, Fujinaga M, Wang L, Belov V, Ogasawara D, Giffenig P, Deng X, Rong J, Yu Q, Zhang X, Papisov MI, Shao Y, Collier TL, Ma JA, Cravatt BF, Josephson L, Zhang MR, Liang SH.

J Med Chem. 2019 Oct 10;62(19):8866-8872. doi: 10.1021/acs.jmedchem.9b00936. Epub 2019 Sep 26.

PMID:
31518130
2.

Diacylglycerol Lipase-Alpha Regulates Hippocampal-Dependent Learning and Memory Processes in Mice.

Schurman LD, Carper MC, Moncayo LV, Ogasawara D, Richardson K, Yu L, Liu X, Poklis JL, Liu QS, Cravatt BF, Lichtman AH.

J Neurosci. 2019 Jul 24;39(30):5949-5965. doi: 10.1523/JNEUROSCI.1353-18.2019. Epub 2019 May 24.

PMID:
31127001
3.

Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan.

Chen AL, Lum KM, Lara-Gonzalez P, Ogasawara D, Cognetta AB 3rd, To A, Parsons WH, Simon GM, Desai A, Petrascheck M, Bar-Peled L, Cravatt BF.

Nat Chem Biol. 2019 May;15(5):453-462. doi: 10.1038/s41589-019-0243-4. Epub 2019 Mar 25.

4.

Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton.

Chen Z, Mori W, Deng X, Cheng R, Ogasawara D, Zhang G, Schafroth MA, Dahl K, Fu H, Hatori A, Shao T, Zhang Y, Yamasaki T, Zhang X, Rong J, Yu Q, Hu K, Fujinaga M, Xie L, Kumata K, Gou Y, Chen J, Gu S, Bao L, Wang L, Collier TL, Vasdev N, Shao Y, Ma JA, Cravatt BF, Fowler C, Josephson L, Zhang MR, Liang SH.

J Med Chem. 2019 Apr 11;62(7):3336-3353. doi: 10.1021/acs.jmedchem.8b01778. Epub 2019 Mar 21.

PMID:
30829483
5.

Discovery and Optimization of Selective and in Vivo Active Inhibitors of the Lysophosphatidylserine Lipase α/β-Hydrolase Domain-Containing 12 (ABHD12).

Ogasawara D, Ichu TA, Jing H, Hulce JJ, Reed A, Ulanovskaya OA, Cravatt BF.

J Med Chem. 2019 Feb 14;62(3):1643-1656. doi: 10.1021/acs.jmedchem.8b01958. Epub 2019 Feb 5.

PMID:
30720278
6.

Global Portrait of Protein Targets of Metabolites of the Neurotoxic Compound BIA 10-2474.

Huang Z, Ogasawara D, Seneviratne UI, Cognetta AB 3rd, Am Ende CW, Nason DM, Lapham K, Litchfield J, Johnson DS, Cravatt BF.

ACS Chem Biol. 2019 Feb 15;14(2):192-197. doi: 10.1021/acschembio.8b01097. Epub 2019 Jan 31.

PMID:
30702848
7.

Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo.

Ogasawara D, Ichu TA, Vartabedian VF, Benthuysen J, Jing H, Reed A, Ulanovskaya OA, Hulce JJ, Roberts A, Brown S, Rosen H, Teijaro JR, Cravatt BF.

Nat Chem Biol. 2018 Dec;14(12):1099-1108. doi: 10.1038/s41589-018-0155-8. Epub 2018 Nov 12.

8.

In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies.

Cheng R, Mori W, Ma L, Alhouayek M, Hatori A, Zhang Y, Ogasawara D, Yuan G, Chen Z, Zhang X, Shi H, Yamasaki T, Xie L, Kumata K, Fujinaga M, Nagai Y, Minamimoto T, Svensson M, Wang L, Du Y, Ondrechen MJ, Vasdev N, Cravatt BF, Fowler C, Zhang MR, Liang SH.

J Med Chem. 2018 Mar 22;61(6):2278-2291. doi: 10.1021/acs.jmedchem.7b01400. Epub 2018 Mar 9.

9.

Stress Promotes Drug Seeking Through Glucocorticoid-Dependent Endocannabinoid Mobilization in the Prelimbic Cortex.

McReynolds JR, Doncheck EM, Li Y, Vranjkovic O, Graf EN, Ogasawara D, Cravatt BF, Baker DA, Liu QS, Hillard CJ, Mantsch JR.

Biol Psychiatry. 2018 Jul 15;84(2):85-94. doi: 10.1016/j.biopsych.2017.09.024. Epub 2017 Oct 6.

10.

Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model.

Wilkerson JL, Donvito G, Grim TW, Abdullah RA, Ogasawara D, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2017 Dec;363(3):394-401. doi: 10.1124/jpet.117.243808. Epub 2017 Oct 2.

11.

Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.

van Esbroeck ACM, Janssen APA, Cognetta AB 3rd, Ogasawara D, Shpak G, van der Kroeg M, Kantae V, Baggelaar MP, de Vrij FMS, Deng H, Allarà M, Fezza F, Lin Z, van der Wel T, Soethoudt M, Mock ED, den Dulk H, Baak IL, Florea BI, Hendriks G, De Petrocellis L, Overkleeft HS, Hankemeier T, De Zeeuw CI, Di Marzo V, Maccarrone M, Cravatt BF, Kushner SA, van der Stelt M.

Science. 2017 Jun 9;356(6342):1084-1087. doi: 10.1126/science.aaf7497.

12.

Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding.

Deng H, Kooijman S, van den Nieuwendijk AM, Ogasawara D, van der Wel T, van Dalen F, Baggelaar MP, Janssen FJ, van den Berg RJ, den Dulk H, Cravatt BF, Overkleeft HS, Rensen PC, van der Stelt M.

J Med Chem. 2017 Jan 12;60(1):428-440. doi: 10.1021/acs.jmedchem.6b01482. Epub 2016 Dec 19.

PMID:
27992221
13.

Solitary tentorial sarcoid granuloma associated with Propionibacterium acnes infection: case report.

Akimoto J, Nagai K, Ogasawara D, Tanaka Y, Izawa H, Kohno M, Uchida K, Eishi Y.

J Neurosurg. 2017 Sep;127(3):687-690. doi: 10.3171/2016.8.JNS16480. Epub 2016 Nov 25.

PMID:
27885956
14.

An in vivo multiplexed small-molecule screening platform.

Grüner BM, Schulze CJ, Yang D, Ogasawara D, Dix MM, Rogers ZN, Chuang CH, McFarland CD, Chiou SH, Brown JM, Cravatt BF, Bogyo M, Winslow MM.

Nat Methods. 2016 Oct;13(10):883-889. doi: 10.1038/nmeth.3992. Epub 2016 Sep 12.

15.

A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation.

Viader A, Ogasawara D, Joslyn CM, Sanchez-Alavez M, Mori S, Nguyen W, Conti B, Cravatt BF.

Elife. 2016 Jan 18;5:e12345. doi: 10.7554/eLife.12345.

16.

Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1-Selective Inactivators.

Itoh Y, Aihara K, Mellini P, Tojo T, Ota Y, Tsumoto H, Solomon VR, Zhan P, Suzuki M, Ogasawara D, Shigenaga A, Inokuma T, Nakagawa H, Miyata N, Mizukami T, Otaka A, Suzuki T.

J Med Chem. 2016 Feb 25;59(4):1531-44. doi: 10.1021/acs.jmedchem.5b01323. Epub 2016 Jan 4.

PMID:
26700437
17.

Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition.

Ogasawara D, Deng H, Viader A, Baggelaar MP, Breman A, den Dulk H, van den Nieuwendijk AM, Soethoudt M, van der Wel T, Zhou J, Overkleeft HS, Sanchez-Alavez M, Mori S, Nguyen W, Conti B, Liu X, Chen Y, Liu QS, Cravatt BF, van der Stelt M.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):26-33. doi: 10.1073/pnas.1522364112. Epub 2015 Dec 14. Erratum in: Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E664. van den Nieuwendijk, Adriann M C H [corrected to van den Nieuwendijk, Adrianus M C H]; Mo, Simone [corrected to Mori, Simone].

18.

Enrichment of O-GlcNAc-modified peptides using novel thiol-alkyne and thiol-disulfide exchange.

Tsumoto H, Ogasawara D, Hashii N, Suzuki T, Akimoto Y, Endo T, Miura Y.

Bioorg Med Chem Lett. 2015 Jul 1;25(13):2645-9. doi: 10.1016/j.bmcl.2015.04.082. Epub 2015 Apr 30.

PMID:
25980911
19.

Effects of human atrial natriuretic peptide on myocardial performance and energetics in heart failure due to previous myocardial infarction.

Ozawa T, Shinke T, Shite J, Takaoka H, Inoue N, Matsumoto H, Watanabe S, Yoshikawa R, Otake H, Matsumoto D, Ogasawara D, Yokoyama M, Hirata K.

J Cardiol. 2015 Sep;66(3):232-8. doi: 10.1016/j.jjcc.2014.12.020. Epub 2015 Feb 23.

20.

Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA Conjugates.

Itoh Y, Ogasawara D, Ota Y, Mizukami T, Suzuki T.

Comput Struct Biotechnol J. 2014 Feb 15;9:e201402002. doi: 10.5936/csbj.201402002. eCollection 2014.

21.

Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism.

Ogasawara D, Itoh Y, Tsumoto H, Kakizawa T, Mino K, Fukuhara K, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N, Suzuki T.

Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8620-4. doi: 10.1002/anie.201303999. Epub 2013 Jul 3. No abstract available.

PMID:
23824985
22.

Pulmonary tumor thrombotic microangiopathy showing aggressive course after transurethral resection of urinary bladder: an autopsy case report.

Hirano H, Ichibori H, Kizaki T, Matsumoto T, Ohka Z, Mori T, Okamoto M, Ogasawara D, Kamemura K, Yoshikawa R, Itagaki T, Matsuda Y, Sano H.

Med Mol Morphol. 2012 Dec;45(4):238-42. doi: 10.1007/s00795-012-0586-3. Epub 2012 Dec 7.

PMID:
23224604
23.

Methyl jasmonate increases the tropane alkaloid scopolamine and reduces natural herbivory in Brugmansia suaveolens: is scopolamine responsible for plant resistance?

Arab A, Alves MN, Sartoratto A, Ogasawara DC, Trigo JR.

Neotrop Entomol. 2012 Feb;41(1):2-8. doi: 10.1007/s13744-011-0001-0. Epub 2012 Feb 10.

PMID:
23950002
24.

Predictive importance of left ventricular myocardial stiffness for the prognosis of patients with congestive heart failure.

Watanabe S, Shite J, Takaoka H, Shinke T, Tanino Y, Otake H, Matsumoto D, Ogasawara D, Sawada T, Hirata K, Yokoyama M.

J Cardiol. 2011 Nov;58(3):245-52. doi: 10.1016/j.jjcc.2011.07.005. Epub 2011 Aug 20.

25.

A set of microsatellite markers for Arrabidaea chica (Bignoniaceae), a medicinal liana from the Neotropics.

Figueira GM, Ramelo PR, Ogasawara DC, Montanari I Jr, Zucchi MI, M Cavallari M, Foglio MA.

Am J Bot. 2010 Jul;97(7):e63-4. doi: 10.3732/ajb.1000145. Epub 2010 Jun 22.

26.

Aptameric sensors based on structural change for diagnosis.

Abe K, Ogasawara D, Yoshida W, Sode K, Ikebukuro K.

Faraday Discuss. 2011;149:93-105; discussion 137-57. Erratum in: Faraday Discuss. 2011;149:106.

PMID:
21413176
27.

Synthesis and biological activity of optically active NCL-1, a lysine-specific demethylase 1 selective inhibitor.

Ogasawara D, Suzuki T, Mino K, Ueda R, Khan MN, Matsubara T, Koseki K, Hasegawa M, Sasaki R, Nakagawa H, Mizukami T, Miyata N.

Bioorg Med Chem. 2011 Jun 15;19(12):3702-8. doi: 10.1016/j.bmc.2010.12.024. Epub 2010 Dec 22.

PMID:
21227703
28.

Non-label homogeneous protein detection based on laser interferometric photo-thermal displacement measurement using aptamers.

Tsukakoshi K, Ogasawara D, Takahashi E, Katayama R, Ikebukuro K.

Biotechnol J. 2011 Jan;6(1):101-6. doi: 10.1002/biot.201000158.

PMID:
21086453
29.

Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.

Hamada S, Suzuki T, Mino K, Koseki K, Oehme F, Flamme I, Ozasa H, Itoh Y, Ogasawara D, Komaarashi H, Kato A, Tsumoto H, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N.

J Med Chem. 2010 Aug 12;53(15):5629-38. doi: 10.1021/jm1003655.

PMID:
20684604
30.

Comparison by optical coherence tomography of paclitaxel-eluting stents with sirolimus-eluting stents implanted in one coronary artery in one procedure. - 6-month follow-up -.

Miyoshi N, Shite J, Shinke T, Otake H, Tanino Y, Ogasawara D, Sawada T, Kawamori H, Kato H, Yoshino N, Kozuki A, Hirata K.

Circ J. 2010 May;74(5):903-8. Epub 2010 Mar 10.

31.

Pyrroloquinoline quinone inhibits the fibrillation of amyloid proteins.

Kim J, Kobayashi M, Fukuda M, Ogasawara D, Kobayashi N, Han S, Nakamura C, Inada M, Miyaura C, Ikebukuro K, Sode K.

Prion. 2010 Jan-Mar;4(1):26-31. Epub 2010 Jan 4.

32.

Factors that influence measurements and accurate evaluation of stent apposition by optical coherence tomography. Assessment using a phantom model.

Sawada T, Shite J, Negi N, Shinke T, Tanino Y, Ogasawara D, Kawamori H, Kato H, Miyoshi N, Yoshino N, Kozuki A, Koto M, Hirata K.

Circ J. 2009 Oct;73(10):1841-7. Epub 2009 Jul 31.

33.

Local determinants of thrombus formation following sirolimus-eluting stent implantation assessed by optical coherence tomography.

Otake H, Shite J, Ako J, Shinke T, Tanino Y, Ogasawara D, Sawada T, Miyoshi N, Kato H, Koo BK, Honda Y, Fitzgerald PJ, Hirata K.

JACC Cardiovasc Interv. 2009 May;2(5):459-66. doi: 10.1016/j.jcin.2009.03.003.

34.

Low plasma adiponectin levels are associated with presence of thin-cap fibroatheroma in men with stable coronary artery disease.

Sawada T, Shite J, Shinke T, Otake H, Tanino Y, Ogasawara D, Kawamori H, Kato H, Miyoshi N, Yoshino N, Kozuki A, Hirata K.

Int J Cardiol. 2010 Jul 23;142(3):250-6. doi: 10.1016/j.ijcard.2008.12.216. Epub 2009 Apr 28.

PMID:
19403182
35.

Whole body bioimpedance monitoring for outpatient chronic heart failure follow up.

Tanino Y, Shite J, Paredes OL, Shinke T, Ogasawara D, Sawada T, Kawamori H, Miyoshi N, Kato H, Yoshino N, Hirata K.

Circ J. 2009 Jun;73(6):1074-9. Epub 2009 Apr 16.

36.

Delayed neointimalization on sirolimus-eluting stents: 6-month and 12-month follow up by optical coherence tomography.

Katoh H, Shite J, Shinke T, Matsumoto D, Tanino Y, Ogasawara D, Sawada T, Miyoshi N, Kawamori H, Yoshino N, Hirata K.

Circ J. 2009 Jun;73(6):1033-7. Epub 2009 Apr 14.

37.

Pioglitazone reduces the necrotic-core component in coronary plaque in association with enhanced plasma adiponectin in patients with type 2 diabetes mellitus.

Ogasawara D, Shite J, Shinke T, Watanabe S, Otake H, Tanino Y, Sawada T, Kawamori H, Kato H, Miyoshi N, Hirata K.

Circ J. 2009 Feb;73(2):343-51. Epub 2008 Dec 18.

38.

Very late thrombosis of sirolimus-eluting stent due to late malapposition: serial observations with optical coherence tomography.

Sawada T, Shite J, Shinke T, Tanino Y, Ogasawara D, Kawamori H, Kato H, Miyoshi N, Yoshino N, Hirata K.

J Cardiol. 2008 Dec;52(3):290-5. doi: 10.1016/j.jjcc.2008.05.003. Epub 2008 Jul 17.

39.

Detection system based on the conformational change in an aptamer and its application to simple bound/free separation.

Ogasawara D, Hachiya NS, Kaneko K, Sode K, Ikebukuro K.

Biosens Bioelectron. 2009 Jan 1;24(5):1372-6. doi: 10.1016/j.bios.2008.07.082. Epub 2008 Aug 20.

PMID:
18809306
40.

Feasibility of combined use of intravascular ultrasound radiofrequency data analysis and optical coherence tomography for detecting thin-cap fibroatheroma.

Sawada T, Shite J, Garcia-Garcia HM, Shinke T, Watanabe S, Otake H, Matsumoto D, Tanino Y, Ogasawara D, Kawamori H, Kato H, Miyoshi N, Yokoyama M, Serruys PW, Hirata K.

Eur Heart J. 2008 May;29(9):1136-46. doi: 10.1093/eurheartj/ehn132. Epub 2008 Apr 7.

PMID:
18397871
41.

Relation between plasma adiponectin, high-sensitivity C-reactive protein, and coronary plaque components in patients with acute coronary syndrome.

Otake H, Shite J, Shinke T, Watanabe S, Tanino Y, Ogasawara D, Sawada T, Hirata K, Yokoyama M.

Am J Cardiol. 2008 Jan 1;101(1):1-7. Epub 2007 Nov 26.

PMID:
18157956
42.

Screening of DNA aptamer against mouse prion protein by competitive selection.

Ogasawara D, Hasegawa H, Kaneko K, Sode K, Ikebukuro K.

Prion. 2007 Oct-Dec;1(4):248-54. Epub 2007 Oct 25.

43.

Catheter-based transcoronary myocardial hypothermia attenuates arrhythmia and myocardial necrosis in pigs with acute myocardial infarction.

Otake H, Shite J, Paredes OL, Shinke T, Yoshikawa R, Tanino Y, Watanabe S, Ozawa T, Matsumoto D, Ogasawara D, Yokoyama M.

J Am Coll Cardiol. 2007 Jan 16;49(2):250-60. Epub 2006 Dec 29.

44.

Neointimal coverage of sirolimus-eluting stents at 6-month follow-up: evaluated by optical coherence tomography.

Matsumoto D, Shite J, Shinke T, Otake H, Tanino Y, Ogasawara D, Sawada T, Paredes OL, Hirata K, Yokoyama M.

Eur Heart J. 2007 Apr;28(8):961-7. Epub 2006 Nov 29.

PMID:
17135281
45.

Persistent malapposition after implantation of sirolimus-eluting stent into intramural coronary hematoma: optical coherence tomography observations.

Sawada T, Shite J, Shinke T, Watanabe S, Otake H, Matsumoto D, Imuro Y, Ogasawara D, Paredes OL, Yokoyama M.

Circ J. 2006 Nov;70(11):1515-9.

46.

[Relationship between high sensitive C-reactive protein and coronary plaque component in patients with acute coronary syndrome: Virtual Histology study].

Sawada T, Shite J, Shinke T, Watanabe S, Otake H, Matsumoto D, Tanino Y, Ogasawara D, Paredes OL, Yokoyama M.

J Cardiol. 2006 Sep;48(3):141-50. Japanese.

PMID:
17007239
47.

Impedance cardiography for cardiac output estimation: reliability of wrist-to-ankle electrode configuration.

Paredes OL, Shite J, Shinke T, Watanabe S, Otake H, Matsumoto D, Imuro Y, Ogasawara D, Sawada T, Yokoyama M.

Circ J. 2006 Sep;70(9):1164-8.

48.

Myocardial stiffness is an important determinant of the plasma brain natriuretic peptide concentration in patients with both diastolic and systolic heart failure.

Watanabe S, Shite J, Takaoka H, Shinke T, Imuro Y, Ozawa T, Otake H, Matsumoto D, Ogasawara D, Paredes OL, Yokoyama M.

Eur Heart J. 2006 Apr;27(7):832-8. Epub 2006 Feb 7.

PMID:
16464912
49.

Beneficial effects of human atrial natriuretic peptide on renal function in a patient with repeated coronary interventions: a case report.

Paredes OL, Shite J, Shinke T, Imuro Y, Yoshikawa R, Watanabe S, Ozawa T, Otake H, Matsumoto D, Ogasawara D, Yokoyama M.

J Cardiol. 2005 Oct;46(4):161-4.

PMID:
16252569
50.

Electrochemical microdevice with separable electrode and antibody chips for simultaneous detection of pepsinogens 1 and 2.

Ogasawara D, Hirano Y, Yasukawa T, Shiku H, Kobori K, Ushizawa K, Kawabata S, Matsue T.

Biosens Bioelectron. 2006 Mar 15;21(9):1784-90. Epub 2005 Oct 21.

PMID:
16243510

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