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Items: 1 to 50 of 64

1.

Nrf2 deficiency in mice attenuates erythropoietic stress-related macrophage hypercellularity.

Gbotosho OT, Kapetanaki MG, Ross M, Ghosh S, Weidert F, Bullock GC, Watkins S, Ofori-Acquah SF, Kato GJ.

Exp Hematol. 2020 Mar 6. pii: S0301-472X(20)30104-1. doi: 10.1016/j.exphem.2020.02.005. [Epub ahead of print]

PMID:
32151553
2.

Hemopexin deficiency promotes acute kidney injury in sickle cell disease.

Ofori-Acquah SF, Hazra R, Orikogbo OO, Crosby D, Flage B, Ackah EB, Lenhart D, Tan RJ, Vitturi DA, Paintsil V, Owusu-Dabo E, Ghosh S; SickleGenAfrica Network.

Blood. 2020 Mar 26;135(13):1044-1048. doi: 10.1182/blood.2019002653.

PMID:
32043112
3.

SickleInAfrica.

Makani J, Sangeda RZ, Nnodu O, Nembaware V, Osei-Akoto A, Paintsil V, Balandya E, Kent J, Luzzatto L, Ofori-Acquah S, Olopade OI, Pallangyo K, Minja IK, Jonas M, Mazandu GK, Mulder N, Ohene-Frempong K, Wonkam A.

Lancet Haematol. 2020 Feb;7(2):e98-e99. doi: 10.1016/S2352-3026(20)30006-5. No abstract available.

PMID:
32004491
4.

Smooth muscle cytochrome b5 reductase 3 deficiency accelerates pulmonary hypertension development in sickle cell mice.

Wood KC, Durgin BG, Schmidt HM, Hahn SA, Baust JJ, Bachman T, Vitturi DA, Ghosh S, Ofori-Acquah SF, Mora AL, Gladwin MT, Straub AC.

Blood Adv. 2019 Dec 10;3(23):4104-4116. doi: 10.1182/bloodadvances.2019000621.

5.

Effects of Individualized Treadmill Endurance Training on Oxidative Stress in Skeletal Muscles of Transgenic Sickle Mice.

Gouraud E, Charrin E, Dubé JJ, Ofori-Acquah SF, Martin C, Skinner S, Chatel B, Boreau A, Messonnier LA, Connes P, Pialoux V, Hautier C, Faes C.

Oxid Med Cell Longev. 2019 Jul 24;2019:3765643. doi: 10.1155/2019/3765643. eCollection 2019.

6.

Free heme regulates placenta growth factor through NRF2-antioxidant response signaling.

Kapetanaki MG, Gbotosho OT, Sharma D, Weidert F, Ofori-Acquah SF, Kato GJ.

Free Radic Biol Med. 2019 Nov 1;143:300-308. doi: 10.1016/j.freeradbiomed.2019.08.009. Epub 2019 Aug 10.

PMID:
31408727
7.

Cardiac expression of HMOX1 and PGF in sickle cell mice and haem-treated wild type mice dominates organ expression profiles via Nrf2 (Nfe2l2).

Gbotosho OT, Ghosh S, Kapetanaki MG, Lin Y, Weidert F, Bullock GC, Ofori-Acquah SF, Kato GJ.

Br J Haematol. 2019 Dec;187(5):666-675. doi: 10.1111/bjh.16129. Epub 2019 Aug 6.

PMID:
31389006
8.

P-selectin plays a role in haem-induced acute lung injury in sickle mice.

Ghosh S, Flage B, Weidert F, Ofori-Acquah SF.

Br J Haematol. 2019 Jul;186(2):329-333. doi: 10.1111/bjh.15807. Epub 2019 Feb 27. No abstract available.

PMID:
30809798
9.

Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease.

Qiu Y, Ahn B, Sakurai Y, Hansen CE, Tran R, Mimche PN, Mannino RG, Ciciliano JC, Lamb TJ, Joiner CH, Ofori-Acquah SF, Lam WA.

Nat Biomed Eng. 2018;2:453-463. doi: 10.1038/s41551-018-0224-z. Epub 2018 Apr 23.

10.

Sleep phenotype in the Townes mouse model of sickle cell disease.

O'Donnell BJ, Guo L, Ghosh S, Shah FA, Strollo PJ Jr, McVerry BJ, Gladwin MT, Ofori-Acquah SF, Kato GJ, O'Donnell CP.

Sleep Breath. 2019 Mar;23(1):333-339. doi: 10.1007/s11325-018-1711-x. Epub 2018 Aug 29.

11.

Augmented NRF2 activation protects adult sickle mice from lethal acute chest syndrome.

Ghosh S, Hazra R, Ihunnah CA, Weidert F, Flage B, Ofori-Acquah SF.

Br J Haematol. 2018 Jul;182(2):271-275. doi: 10.1111/bjh.15401. Epub 2018 Jun 19.

PMID:
29923176
12.

Prevalence of relative systemic hypertension in adults with sickle cell disease in Ghana.

Benneh-Akwasi Kuma A, Owusu-Ansah AT, Ampomah MA, Sey F, Olayemi E, Nouraie M, Ofori-Acquah SF.

PLoS One. 2018 Jan 4;13(1):e0190347. doi: 10.1371/journal.pone.0190347. eCollection 2018.

13.

Organ damage in sickle cell disease study (ORDISS): protocol for a longitudinal cohort study based in Ghana.

Anie KA, Paintsil V, Owusu-Dabo E, Ansong D, Osei-Akoto A, Ohene-Frempong K, Amissah KA, Addofoh N, Ackah EB, Owusu-Ansah AT, Ofori-Acquah SF.

BMJ Open. 2017 Aug 28;7(8):e016727. doi: 10.1136/bmjopen-2017-016727.

14.

Sickle cell disease: tipping the balance of genomic research to catalyse discoveries in Africa.

Makani J, Ofori-Acquah SF, Tluway F, Mulder N, Wonkam A.

Lancet. 2017 Jun 17;389(10087):2355-2358. doi: 10.1016/S0140-6736(17)31615-X. Epub 2017 Jun 15. No abstract available.

15.

Moderate exercise training decreases inflammation in transgenic sickle cell mice.

Charrin E, Dubé JJ, Connes P, Pialoux V, Ghosh S, Faes C, Ofori-Acquah SF, Martin C.

Blood Cells Mol Dis. 2018 Mar;69:45-52. doi: 10.1016/j.bcmd.2017.06.002. Epub 2017 Jun 13.

PMID:
28624257
16.

Inflammatory and oxidative stress phenotypes in transgenic sickle cell mice.

Charrin E, Ofori-Acquah SF, Nader E, Skinner S, Connes P, Pialoux V, Joly P, Martin C.

Blood Cells Mol Dis. 2016 Nov;62:13-21. doi: 10.1016/j.bcmd.2016.10.020. Epub 2016 Oct 28.

PMID:
27835777
17.

Sustained enhancement of OCTN1 transporter expression in association with hydroxyurea induced γ-globin expression in erythroid progenitors.

Walker AL, Ofori-Acquah SF.

Exp Hematol. 2017 Jan;45:69-73.e2. doi: 10.1016/j.exphem.2016.09.001. Epub 2016 Sep 8.

18.

Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia.

Lei J, Benson B, Tran H, Ofori-Acquah SF, Gupta K.

PLoS One. 2016 Aug 5;11(8):e0160608. doi: 10.1371/journal.pone.0160608. eCollection 2016.

19.

Proceedings of a Sickle Cell Disease Ontology workshop - Towards the first comprehensive ontology for Sickle Cell Disease.

Mulder N, Nembaware V, Adekile A, Anie KA, Inusa B, Brown B, Campbell A, Chinenere F, Chunda-Liyoka C, Derebail VK, Geard A, Ghedira K, Hamilton CM, Hanchard NA, Haendel M, Huggins W, Ibrahim M, Jupp S, Kamga KK, Knight-Madden J, Lopez-Sall P, Mbiyavanga M, Munube D, Nirenberg D, Nnodu O, Ofori-Acquah SF, Ohene-Frempong K, Opap KB, Panji S, Park M, Pule G, Royal C, Sangeda R, Tayo B, Treadwell M, Tshilolo L, Wonkam A.

Appl Transl Genom. 2016 Mar 15;9:23-9. doi: 10.1016/j.atg.2016.03.005. eCollection 2016 Jun.

20.

Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity.

Buland JR, Wasserloos KJ, Tyurin VA, Tyurina YY, Amoscato AA, Mallampalli RK, Chen BB, Zhao J, Zhao Y, Ofori-Acquah S, Kagan VE, Pitt BR.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L303-16. doi: 10.1152/ajplung.00038.2016. Epub 2016 May 27.

21.

Nonhematopoietic Nrf2 dominantly impedes adult progression of sickle cell anemia in mice.

Ghosh S, Ihunnah CA, Hazra R, Walker AL, Hansen JM, Archer DR, Owusu-Ansah AT, Ofori-Acquah SF.

JCI Insight. 2016;1(4). pii: 81090. doi: 10.1172/jci.insight.81090. Epub 2016 Apr 7.

22.

Original Research: Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model.

Tan F, Ghosh S, Mosunjac M, Manci E, Ofori-Acquah SF.

Exp Biol Med (Maywood). 2016 Apr;241(7):766-71. doi: 10.1177/1535370216642046. Epub 2016 Mar 29.

23.

Inflammatory targets of therapy in sickle cell disease.

Owusu-Ansah A, Ihunnah CA, Walker AL, Ofori-Acquah SF.

Transl Res. 2016 Jan;167(1):281-97. doi: 10.1016/j.trsl.2015.07.001. Epub 2015 Jul 11. Review.

24.

Microarchitectural and mechanical characterization of the sickle bone.

Green M, Akinsami I, Lin A, Banton S, Ghosh S, Chen B, Platt M, Osunkwo I, Ofori-Acquah S, Guldberg R, Barabino G.

J Mech Behav Biomed Mater. 2015 Aug;48:220-228. doi: 10.1016/j.jmbbm.2015.04.019. Epub 2015 Apr 24.

25.

Enhanced down-regulation of ALCAM/CD166 in African-American Breast Cancer.

Tan F, Mosunjac M, Adams AL, Adade B, Taye O, Hu Y, Rizzo M, Ofori-Acquah SF.

BMC Cancer. 2014 Sep 25;14:715. doi: 10.1186/1471-2407-14-715.

26.

Using formative research to develop a counselor training program for newborn screening in Ghana.

Treadwell MJ, Anie KA, Grant AM, Ofori-Acquah SF, Ohene-Frempong K.

J Genet Couns. 2015 Apr;24(2):267-77. doi: 10.1007/s10897-014-9759-7. Epub 2014 Sep 7.

27.

Research capacity. Enabling the genomic revolution in Africa.

H3Africa Consortium, Rotimi C, Abayomi A, Abimiku A, Adabayeri VM, Adebamowo C, Adebiyi E, Ademola AD, Adeyemo A, Adu D, Affolabi D, Agongo G, Ajayi S, Akarolo-Anthony S, Akinyemi R, Akpalu A, Alberts M, Alonso Betancourt O, Alzohairy AM, Ameni G, Amodu O, Anabwani G, Andersen K, Arogundade F, Arulogun O, Asogun D, Bakare R, Balde N, Baniecki ML, Beiswanger C, Benkahla A, Bethke L, Boehnke M, Boima V, Brandful J, Brooks AI, Brosius FC, Brown C, Bucheton B, Burke DT, Burnett BG, Carrington-Lawrence S, Carstens N, Chisi J, Christoffels A, Cooper R, Cordell H, Crowther N, Croxton T, de Vries J, Derr L, Donkor P, Doumbia S, Duncanson A, Ekem I, El Sayed A, Engel ME, Enyaru JC, Everett D, Fadlelmola FM, Fakunle E, Fischbeck KH, Fischer A, Folarin O, Gamieldien J, Garry RF, Gaseitsiwe S, Gbadegesin R, Ghansah A, Giovanni M, Goesbeck P, Gomez-Olive FX, Grant DS, Grewal R, Guyer M, Hanchard NA, Happi CT, Hazelhurst S, Hennig BJ, Hertz- C, Fowler, Hide W, Hilderbrandt F, Hugo-Hamman C, Ibrahim ME, James R, Jaufeerally-Fakim Y, Jenkins C, Jentsch U, Jiang PP, Joloba M, Jongeneel V, Joubert F, Kader M, Kahn K, Kaleebu P, Kapiga SH, Kassim SK, Kasvosve I, Kayondo J, Keavney B, Kekitiinwa A, Khan SH, Kimmel P, King MC, Kleta R, Koffi M, Kopp J, Kretzler M, Kumuthini J, Kyobe S, Kyobutungi C, Lackland DT, Lacourciere KA, Landouré G, Lawlor R, Lehner T, Lesosky M, Levitt N, Littler K, Lombard Z, Loring JF, Lyantagaye S, Macleod A, Madden EB, Mahomva CR, Makani J, Mamven M, Marape M, Mardon G, Marshall P, Martin DP, Masiga D, Mason R, Mate-Kole M, Matovu E, Mayige M, Mayosi BM, Mbanya JC, McCurdy SA, McCarthy MI, McIlleron H, Mc'Ligeyo SO, Merle C, Mocumbi AO, Mondo C, Moran JV, Motala A, Moxey-Mims M, Mpoloka WS, Msefula CL, Mthiyane T, Mulder N, Mulugeta Gh, Mumba D, Musuku J, Nagdee M, Nash O, Ndiaye D, Nguyen AQ, Nicol M, Nkomazana O, Norris S, Nsangi B, Nyarko A, Nyirenda M, Obe E, Obiakor R, Oduro A, Ofori-Acquah SF, Ogah O, Ogendo S, Ohene-Frempong K, Ojo A, Olanrewaju T, Oli J, Osafo C, Ouwe Missi Oukem-Boyer O, Ovbiagele B, Owen A, Owolabi MO, Owolabi L, Owusu-Dabo E, Pare G, Parekh R, Patterton HG, Penno MB, Peterson J, Pieper R, Plange-Rhule J, Pollak M, Puzak J, Ramesar RS, Ramsay M, Rasooly R, Reddy S, Sabeti PC, Sagoe K, Salako T, Samassékou O, Sandhu MS, Sankoh O, Sarfo FS, Sarr M, Shaboodien G, Sidibe I, Simo G, Simuunza M, Smeeth L, Sobngwi E, Soodyall H, Sorgho H, Sow Bah O, Srinivasan S, Stein DJ, Susser ES, Swanepoel C, Tangwa G, Tareila A, Tastan Bishop O, Tayo B, Tiffin N, Tinto H, Tobin E, Tollman SM, Traoré M, Treadwell MJ, Troyer J, Tsimako-Johnstone M, Tukei V, Ulasi I, Ulenga N, van Rooyen B, Wachinou AP, Waddy SP, Wade A, Wayengera M, Whitworth J, Wideroff L, Winkler CA, Winnicki S, Wonkam A, Yewondwos M, sen T, Yozwiak N, Zar H.

Science. 2014 Jun 20;344(6190):1346-8. doi: 10.1126/science.1251546. No abstract available.

28.

Erythroid DAMPs drive inflammation in SCD.

Gladwin MT, Ofori-Acquah SF.

Blood. 2014 Jun 12;123(24):3689-90. doi: 10.1182/blood-2014-03-563874. No abstract available.

29.

High protein diet attenuates histopathologic organ damage and vascular leakage in transgenic murine model of sickle cell anemia.

Manci EA, Hyacinth HI, Capers PL, Archer DR, Pitts S, Ghosh S, Patrickson J, Titford ME, Ofori-Acquah SF, Hibbert JM.

Exp Biol Med (Maywood). 2014 Aug;239(8):966-974. Epub 2014 May 19.

30.

Extracellular hemin crisis triggers acute chest syndrome in sickle mice.

Ghosh S, Adisa OA, Chappa P, Tan F, Jackson KA, Archer DR, Ofori-Acquah SF.

J Clin Invest. 2013 Nov;123(11):4809-20.

31.

Association between plasma free haem and incidence of vaso-occlusive episodes and acute chest syndrome in children with sickle cell disease.

Adisa OA, Hu Y, Ghosh S, Aryee D, Osunkwo I, Ofori-Acquah SF.

Br J Haematol. 2013 Sep;162(5):702-5. doi: 10.1111/bjh.12445. Epub 2013 Jun 27.

32.

Sickle cell disease: new opportunities and challenges in Africa.

Makani J, Ofori-Acquah SF, Nnodu O, Wonkam A, Ohene-Frempong K.

ScientificWorldJournal. 2013;2013:193252. doi: 10.1155/2013/193252. Epub 2013 Sep 19. Review.

33.

Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease.

Bean CJ, Boulet SL, Ellingsen D, Pyle ME, Barron-Casella EA, Casella JF, Payne AB, Driggers J, Trau HA, Yang G, Jones K, Ofori-Acquah SF, Hooper WC, DeBaun MR.

Blood. 2012 Nov 1;120(18):3822-8. doi: 10.1182/blood-2011-06-361642. Epub 2012 Sep 10.

34.

Sickle cell disease: genetics, cellular and molecular mechanisms, and therapies.

Pace BS, Ofori-Acquah SF, Peterson KR.

Anemia. 2012;2012:143594. doi: 10.1155/2012/143594. Epub 2012 Aug 22. No abstract available.

35.
36.

High dose vitamin D therapy for chronic pain in children and adolescents with sickle cell disease: results of a randomized double blind pilot study.

Osunkwo I, Ziegler TR, Alvarez J, McCracken C, Cherry K, Osunkwo CE, Ofori-Acquah SF, Ghosh S, Ogunbobode A, Rhodes J, Eckman JR, Dampier C, Tangpricha V.

Br J Haematol. 2012 Oct;159(2):211-5. doi: 10.1111/bjh.12019. Epub 2012 Aug 28.

37.

Spatiotemporal dysfunction of the vascular permeability barrier in transgenic mice with sickle cell disease.

Ghosh S, Tan F, Ofori-Acquah SF.

Anemia. 2012;2012:582018. doi: 10.1155/2012/582018. Epub 2012 Jun 12.

38.

Elevated circulating angiogenic progenitors and white blood cells are associated with hypoxia-inducible angiogenic growth factors in children with sickle cell disease.

Ofori-Acquah SF, Buchanan ID, Osunkwo I, Manlove-Simmons J, Lawal F, Quarshie A, Quyyumi AA, Gibbons GH, Gee BE.

Anemia. 2012;2012:156598. doi: 10.1155/2012/156598. Epub 2012 May 23.

39.

Heme mediated STAT3 activation in severe malaria.

Liu M, Amodu AS, Pitts S, Patrickson J, Hibbert JM, Battle M, Ofori-Acquah SF, Stiles JK.

PLoS One. 2012;7(3):e34280. doi: 10.1371/journal.pone.0034280. Epub 2012 Mar 30.

40.

Alloimmunization to transfused HOD red blood cells is not increased in mice with sickle cell disease.

Hendrickson JE, Hod EA, Perry JR, Ghosh S, Chappa P, Adisa O, Kean LS, Ofori-Acquah SF, Archer DR, Spitalnik SL, Zimring JC.

Transfusion. 2012 Feb;52(2):231-40. doi: 10.1111/j.1537-2995.2011.03255.x. Epub 2011 Jul 25.

41.

Global gene expression profiling of endothelium exposed to heme reveals an organ-specific induction of cytoprotective enzymes in sickle cell disease.

Ghosh S, Tan F, Yu T, Li Y, Adisa O, Mosunjac M, Ofori-Acquah SF.

PLoS One. 2011 Mar 31;6(3):e18399. doi: 10.1371/journal.pone.0018399.

42.

Vitamin D deficiency and chronic pain in sickle cell disease.

Osunkwo I, Hodgman EI, Cherry K, Dampier C, Eckman J, Ziegler TR, Ofori-Acquah S, Tangpricha V.

Br J Haematol. 2011 May;153(4):538-40. doi: 10.1111/j.1365-2141.2010.08458.x. Epub 2011 Jan 31. No abstract available.

PMID:
21275953
43.

Essential role for ALCAM gene silencing in megakaryocytic differentiation of K562 cells.

Tan F, Ghosh S, Mbeunkui F, Thomas R, Weiner JA, Ofori-Acquah SF.

BMC Mol Biol. 2010 Dec 2;11:91. doi: 10.1186/1471-2199-11-91.

44.

Mechanisms of transcriptional regulation and prognostic significance of activated leukocyte cell adhesion molecule in cancer.

King JA, Tan F, Mbeunkui F, Chambers Z, Cantrell S, Chen H, Alvarez D, Shevde LA, Ofori-Acquah SF.

Mol Cancer. 2010 Oct 7;9:266. doi: 10.1186/1476-4598-9-266.

45.

Role of STAT3 and GATA-1 interactions in gamma-globin gene expression.

Yao X, Kodeboyina S, Liu L, Dzandu J, Sangerman J, Ofori-Acquah SF, Pace BS.

Exp Hematol. 2009 Aug;37(8):889-900. doi: 10.1016/j.exphem.2009.05.004. Epub 2009 May 15.

46.

Is N-cadherin expression important in ductal carcinoma?

King JA, Shevde LA, Ofori-Acquah S, Watkins G, Jiang WG.

South Med J. 2008 May;101(5):470-5. doi: 10.1097/SMJ.0b013e31816c0112.

PMID:
18414176
47.

Activated leukocyte cell adhesion molecule: a new paradox in cancer.

Ofori-Acquah SF, King JA.

Transl Res. 2008 Mar;151(3):122-8. doi: 10.1016/j.trsl.2007.09.006. Epub 2007 Oct 23. Review.

PMID:
18279810
48.

Heterogeneity of barrier function in the lung reflects diversity in endothelial cell junctions.

Ofori-Acquah SF, King J, Voelkel N, Schaphorst KL, Stevens T.

Microvasc Res. 2008 Apr;75(3):391-402. Epub 2007 Nov 7.

49.
50.

Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves gamma-globin activation by CREB1 and ATF-2.

Sangerman J, Lee MS, Yao X, Oteng E, Hsiao CH, Li W, Zein S, Ofori-Acquah SF, Pace BS.

Blood. 2006 Nov 15;108(10):3590-9. Epub 2006 Aug 8.

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