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Items: 1 to 50 of 224

1.

Identification of root transcriptional responses to shoot illumination in Arabidopsis thaliana.

Miotto YE, Tesser da Costa C, de Oliveira BH, Guzman F, Margis R, de Almeida RMC, Offringa R, Dos Santos Maraschin F.

Plant Mol Biol. 2019 Sep 27. doi: 10.1007/s11103-019-00918-7. [Epub ahead of print]

PMID:
31560104
2.

Sensitization of Tumors for Attack by Virus-Specific CD8+ T-Cells Through Antibody-Mediated Delivery of Immunogenic T-Cell Epitopes.

Sefrin JP, Hillringhaus L, Mundigl O, Mann K, Ziegler-Landesberger D, Seul H, Tabares G, Knoblauch D, Leinenbach A, Friligou I, Dziadek S, Offringa R, Lifke V, Lifke A.

Front Immunol. 2019 Aug 21;10:1962. doi: 10.3389/fimmu.2019.01962. eCollection 2019.

3.

Optimized dendritic cell vaccination induces potent CD8 T cell responses and anti-tumor effects in transgenic mouse melanoma models.

Grees M, Sharbi-Yunger A, Evangelou C, Baumann D, Cafri G, Tzehoval E, Eichmüller SB, Offringa R, Utikal J, Eisenbach L, Umansky V.

Oncoimmunology. 2018 Mar 26;7(7):e1445457. doi: 10.1080/2162402X.2018.1445457. eCollection 2018.

4.

Comparative adventitious root development in pre-etiolated and flooded Arabidopsis hypocotyls exposed to different auxins.

da Costa CT, Gaeta ML, de Araujo Mariath JE, Offringa R, Fett-Neto AG.

Plant Physiol Biochem. 2018 Jun;127:161-168. doi: 10.1016/j.plaphy.2018.03.022. Epub 2018 Mar 21.

PMID:
29604522
5.

Digital Diabetes Management Application Improves Glycemic Outcomes in People With Type 1 and Type 2 Diabetes.

Offringa R, Sheng T, Parks L, Clements M, Kerr D, Greenfield MS.

J Diabetes Sci Technol. 2018 May;12(3):701-708. doi: 10.1177/1932296817747291. Epub 2017 Dec 25.

6.

Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications.

Cabo M, Offringa R, Zitvogel L, Kroemer G, Muntasell A, Galluzzi L.

Oncoimmunology. 2017 Aug 30;6(12):e1371896. doi: 10.1080/2162402X.2017.1371896. eCollection 2017. Review.

7.

Auxin Homeostasis in Arabidopsis Ovules Is Anther-Dependent at Maturation and Changes Dynamically upon Fertilization.

Larsson E, Vivian-Smith A, Offringa R, Sundberg E.

Front Plant Sci. 2017 Oct 10;8:1735. doi: 10.3389/fpls.2017.01735. eCollection 2017.

8.

Diminished medial prefrontal cortex activation during the recollection of stressful events is an acquired characteristic of PTSD.

Dahlgren MK, Laifer LM, VanElzakker MB, Offringa R, Hughes KC, Staples-Bradley LK, Dubois SJ, Lasko NB, Hinojosa CA, Orr SP, Pitman RK, Shin LM.

Psychol Med. 2018 May;48(7):1128-1138. doi: 10.1017/S003329171700263X. Epub 2017 Sep 12.

9.

Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma.

Poschke I, Faryna M, Bergmann F, Flossdorf M, Lauenstein C, Hermes J, Hinz U, Hank T, Ehrenberg R, Volkmar M, Loewer M, Glimm H, Hackert T, Sprick MR, Höfer T, Trumpp A, Halama N, Hassel JC, Strobel O, Büchler M, Sahin U, Offringa R.

Oncoimmunology. 2016 Oct 7;5(12):e1240859. doi: 10.1080/2162402X.2016.1240859. eCollection 2016.

10.

Next-generation TCR sequencing - a tool to understand T-cell infiltration in human cancers.

Poschke I, Flossdorf M, Offringa R.

J Pathol. 2016 Dec;240(4):384-386. doi: 10.1002/path.4800. Epub 2016 Oct 21.

PMID:
27569598
11.

Association of genetic polymorphisms with survival of pancreatic ductal adenocarcinoma patients.

Rizzato C, Campa D, Talar-Wojnarowska R, Halloran C, Kupcinskas J, Butturini G, Mohelníková-Duchoňová B, Sperti C, Tjaden C, Ghaneh P, Hackert T, Funel N, Giese N, Tavano F, Pezzilli R, Pedata M, Pasquali C, Gazouli M, Mambrini A, Souček P, di Sebastiano P, Capurso G, Cantore M, Oliverius M, Offringa R, Małecka-Panas E, Strobel O, Scarpa A, Canzian F.

Carcinogenesis. 2016 Oct;37(10):957-64. doi: 10.1093/carcin/bgw080. Epub 2016 Aug 5.

PMID:
27497070
12.

Personal and Financial Risk Typologies Among Women Who Engage in Sex Work in Mongolia: A Latent Class Analysis.

Offringa R, Tsai LC, Aira T, Riedel M, Witte SS.

Arch Sex Behav. 2017 Aug;46(6):1857-1866. doi: 10.1007/s10508-016-0824-1. Epub 2016 Jul 29.

13.

An INDEHISCENT-Controlled Auxin Response Specifies the Separation Layer in Early Arabidopsis Fruit.

van Gelderen K, van Rongen M, Liu A, Otten A, Offringa R.

Mol Plant. 2016 Jun 6;9(6):857-69. doi: 10.1016/j.molp.2016.03.005. Epub 2016 Mar 16.

14.

Toward a Molecular Understanding of Plant Hormone Actions.

Li C, Li J, Chong K, Harter K, Lee Y, Leung J, Martinoia E, Matsuoka M, Offringa R, Qu L, Schroeder J, Zhao Y.

Mol Plant. 2016 Jan 4;9(1):1-3. doi: 10.1016/j.molp.2015.12.006. Epub 2015 Dec 18. No abstract available.

15.

Modelling the dynamics of polar auxin transport in inflorescence stems of Arabidopsis thaliana.

Boot KJ, Hille SC, Libbenga KR, Peletier LA, van Spronsen PC, van Duijn B, Offringa R.

J Exp Bot. 2016 Feb;67(3):649-66. doi: 10.1093/jxb/erv471. Epub 2015 Nov 2.

16.

Development of Next-Generation Immunomodulatory Antibodies for Cancer Therapy through Optimization of the IgG Framework.

Offringa R, Glennie MJ.

Cancer Cell. 2015 Sep 14;28(3):273-5. doi: 10.1016/j.ccell.2015.08.008.

17.

Plasma membrane-bound AGC3 kinases phosphorylate PIN auxin carriers at TPRXS(N/S) motifs to direct apical PIN recycling.

Dhonukshe P, Huang F, Galvan-Ampudia CS, Mähönen AP, Kleine-Vehn J, Xu J, Quint A, Prasad K, Friml J, Scheres B, Offringa R.

Development. 2015 Jul 1;142(13):2386-7. doi: 10.1242/dev.127415. No abstract available.

18.

Cancer immunotherapy: exploiting neoepitopes.

Platten M, Offringa R.

Cell Res. 2015 Aug;25(8):887-8. doi: 10.1038/cr.2015.66. Epub 2015 Jun 2.

19.

Auxin Binding Protein 1: A Red Herring After All?

Habets ME, Offringa R.

Mol Plant. 2015 Aug;8(8):1131-4. doi: 10.1016/j.molp.2015.04.010. Epub 2015 Apr 25. No abstract available.

20.

A high-throughput RNAi screen for detection of immune-checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes.

Khandelwal N, Breinig M, Speck T, Michels T, Kreutzer C, Sorrentino A, Sharma AK, Umansky L, Conrad H, Poschke I, Offringa R, König R, Bernhard H, Machlenkin A, Boutros M, Beckhove P.

EMBO Mol Med. 2015 Apr;7(4):450-63. doi: 10.15252/emmm.201404414.

21.

Efficacy of a savings-led microfinance intervention to reduce sexual risk for HIV among women engaged in sex work: a randomized clinical trial.

Witte SS, Aira T, Tsai LC, Riedel M, Offringa R, Chang M, El-Bassel N, Ssewamala F.

Am J Public Health. 2015 Mar;105(3):e95-102. doi: 10.2105/AJPH.2014.302291. Epub 2015 Jan 20.

22.

Plasticity in Cell Division Patterns and Auxin Transport Dependency during in Vitro Embryogenesis in Brassica napus.

Soriano M, Li H, Jacquard C, Angenent GC, Krochko J, Offringa R, Boutilier K.

Plant Cell. 2014 Jun;26(6):2568-2581. Epub 2014 Jun 20.

23.

PIN-driven polar auxin transport in plant developmental plasticity: a key target for environmental and endogenous signals.

Habets ME, Offringa R.

New Phytol. 2014 Jul;203(2):362-77. doi: 10.1111/nph.12831. Epub 2014 May 27. Review.

24.

Cytokinin controls polarity of PIN1-dependent auxin transport during lateral root organogenesis.

Marhavý P, Duclercq J, Weller B, Feraru E, Bielach A, Offringa R, Friml J, Schwechheimer C, Murphy A, Benková E.

Curr Biol. 2014 May 5;24(9):1031-7. doi: 10.1016/j.cub.2014.04.002. Epub 2014 Apr 24.

25.

Prevailing role of contact guidance in intrastromal T-cell trapping in human pancreatic cancer.

Hartmann N, Giese NA, Giese T, Poschke I, Offringa R, Werner J, Ryschich E.

Clin Cancer Res. 2014 Jul 1;20(13):3422-33. doi: 10.1158/1078-0432.CCR-13-2972. Epub 2014 Apr 24.

26.

Efficient gene targeting in Penicillium chrysogenum using novel Agrobacterium-mediated transformation approaches.

de Boer P, Bronkhof J, Dukiќ K, Kerkman R, Touw H, van den Berg M, Offringa R.

Fungal Genet Biol. 2013 Dec;61:9-14. doi: 10.1016/j.fgb.2013.08.012. Epub 2013 Aug 28.

PMID:
23994321
27.

Cell polarity and development.

Offringa R, Kleine-Vehn J.

J Integr Plant Biol. 2013 Sep;55(9):786-8. doi: 10.1111/jipb.12099. No abstract available.

PMID:
23953999
28.

Phosphorylation-dependent trafficking of plasma membrane proteins in animal and plant cells.

Offringa R, Huang F.

J Integr Plant Biol. 2013 Sep;55(9):789-808. doi: 10.1111/jipb.12096. Review.

PMID:
23945267
29.

Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response.

Karim R, Tummers B, Meyers C, Biryukov JL, Alam S, Backendorf C, Jha V, Offringa R, van Ommen GJ, Melief CJ, Guardavaccaro D, Boer JM, van der Burg SH.

PLoS Pathog. 2013;9(5):e1003384. doi: 10.1371/journal.ppat.1003384. Epub 2013 May 23.

30.

Diminished rostral anterior cingulate cortex activation during trauma-unrelated emotional interference in PTSD.

Offringa R, Handwerger Brohawn K, Staples LK, Dubois SJ, Hughes KC, Pfaff DL, Vanelzakker MB, Davis FC, Shin LM.

Biol Mood Anxiety Disord. 2013 May 14;3(1):10. doi: 10.1186/2045-5380-3-10.

31.

Evolutionary Adaptations of Plant AGC Kinases: From Light Signaling to Cell Polarity Regulation.

Rademacher EH, Offringa R.

Front Plant Sci. 2012 Nov 16;3:250. doi: 10.3389/fpls.2012.00250. eCollection 2012.

32.

Physiological and morphological changes during early and later stages of fruit growth in Capsicum annuum.

Tiwari A, Vivian-Smith A, Ljung K, Offringa R, Heuvelink E.

Physiol Plant. 2013 Mar;147(3):396-406. doi: 10.1111/j.1399-3054.2012.01673.x. Epub 2012 Sep 13.

PMID:
22889158
33.

Polar auxin transport: an early invention.

Boot KJ, Libbenga KR, Hille SC, Offringa R, van Duijn B.

J Exp Bot. 2012 Jun;63(11):4213-8. doi: 10.1093/jxb/ers106. Epub 2012 Apr 2.

34.

Parthenocarpic potential in Capsicum annuum L. is enhanced by carpelloid structures and controlled by a single recessive gene.

Tiwari A, Vivian-Smith A, Voorrips RE, Habets ME, Xue LB, Offringa R, Heuvelink EP.

BMC Plant Biol. 2011 Oct 21;11:143. doi: 10.1186/1471-2229-11-143.

35.

Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes.

Karim R, Meyers C, Backendorf C, Ludigs K, Offringa R, van Ommen GJ, Melief CJ, van der Burg SH, Boer JM.

PLoS One. 2011 Mar 14;6(3):e17848. doi: 10.1371/journal.pone.0017848.

36.

CD40 pathway activation status predicts response to CD40 therapy in diffuse large B cell lymphoma.

Burington B, Yue P, Shi X, Advani R, Lau JT, Tan J, Stinson S, Stinson J, Januario T, de Vos S, Ansell S, Forero-Torres A, Fedorowicz G, Yang TT, Elkins K, Du C, Mohan S, Yu N, Modrusan Z, Seshagiri S, Yu SF, Pandita A, Koeppen H, French D, Polson AG, Offringa R, Whiting N, Ebens A, Dornan D.

Sci Transl Med. 2011 Mar 16;3(74):74ra22. doi: 10.1126/scitranslmed.3001620.

37.

Light-mediated polarization of the PIN3 auxin transporter for the phototropic response in Arabidopsis.

Ding Z, Galván-Ampudia CS, Demarsy E, Łangowski Ł, Kleine-Vehn J, Fan Y, Morita MT, Tasaka M, Fankhauser C, Offringa R, Friml J.

Nat Cell Biol. 2011 Apr;13(4):447-52. doi: 10.1038/ncb2208. Epub 2011 Mar 13.

PMID:
21394084
38.

An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells.

Wilson NS, Yang B, Yang A, Loeser S, Marsters S, Lawrence D, Li Y, Pitti R, Totpal K, Yee S, Ross S, Vernes JM, Lu Y, Adams C, Offringa R, Kelley B, Hymowitz S, Daniel D, Meng G, Ashkenazi A.

Cancer Cell. 2011 Jan 18;19(1):101-13. doi: 10.1016/j.ccr.2010.11.012.

39.

The neural correlates of emotional memory in posttraumatic stress disorder.

Brohawn KH, Offringa R, Pfaff DL, Hughes KC, Shin LM.

Biol Psychiatry. 2010 Dec 1;68(11):1023-30. doi: 10.1016/j.biopsych.2010.07.018. Epub 2010 Sep 19.

PMID:
20855060
40.

Plasma membrane-bound AGC3 kinases phosphorylate PIN auxin carriers at TPRXS(N/S) motifs to direct apical PIN recycling.

Dhonukshe P, Huang F, Galvan-Ampudia CS, Mähönen AP, Kleine-Vehn J, Xu J, Quint A, Prasad K, Friml J, Scheres B, Offringa R.

Development. 2010 Oct;137(19):3245-55. doi: 10.1242/dev.052456. Erratum in: Development. 2015 Jul 1;142(13):2386-7.

41.

Evaluation of immunological cross-reactivity between clade A9 high-risk human papillomavirus types on the basis of E6-Specific CD4+ memory T cell responses.

van den Hende M, Redeker A, Kwappenberg KM, Franken KL, Drijfhout JW, Oostendorp J, Valentijn AR, Fathers LM, Welters MJ, Melief CJ, Kenter GG, van der Burg SH, Offringa R.

J Infect Dis. 2010 Oct 15;202(8):1200-11. doi: 10.1086/656367.

PMID:
20822453
42.

Separate roles for antigen recognition and lymph node inflammation in CD8+ memory T cell formation.

Fransen MF, van Stipdonk MJ, Sluijter M, Schoenberger SP, Melief CJ, Offringa R.

J Immunol. 2010 Sep 15;185(6):3167-73. doi: 10.4049/jimmunol.0904046. Epub 2010 Aug 9.

43.

Highly efficient gene targeting in Penicillium chrysogenum using the bi-partite approach in deltalig4 or deltaku70 mutants.

de Boer P, Bastiaans J, Touw H, Kerkman R, Bronkhof J, van den Berg M, Offringa R.

Fungal Genet Biol. 2010 Oct;47(10):839-46. doi: 10.1016/j.fgb.2010.07.008. Epub 2010 Jul 24.

PMID:
20659576
44.

Phosphorylation of conserved PIN motifs directs Arabidopsis PIN1 polarity and auxin transport.

Huang F, Zago MK, Abas L, van Marion A, Galván-Ampudia CS, Offringa R.

Plant Cell. 2010 Apr;22(4):1129-42. doi: 10.1105/tpc.109.072678. Epub 2010 Apr 20.

45.

PIN auxin efflux carrier polarity is regulated by PINOID kinase-mediated recruitment into GNOM-independent trafficking in Arabidopsis.

Kleine-Vehn J, Huang F, Naramoto S, Zhang J, Michniewicz M, Offringa R, Friml J.

Plant Cell. 2009 Dec;21(12):3839-49. doi: 10.1105/tpc.109.071639. Epub 2009 Dec 29.

46.

The nonpolymorphic MHC Qa-1b mediates CD8+ T cell surveillance of antigen-processing defects.

Oliveira CC, van Veelen PA, Querido B, de Ru A, Sluijter M, Laban S, Drijfhout JW, van der Burg SH, Offringa R, van Hall T.

J Exp Med. 2010 Jan 18;207(1):207-21. doi: 10.1084/jem.20091429. Epub 2009 Dec 28. Erratum in: J Exp Med. 2010 Mar 15;207(3):671. Drijfhout, Jan W [added].

47.

Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia.

Kenter GG, Welters MJ, Valentijn AR, Lowik MJ, Berends-van der Meer DM, Vloon AP, Essahsah F, Fathers LM, Offringa R, Drijfhout JW, Wafelman AR, Oostendorp J, Fleuren GJ, van der Burg SH, Melief CJ.

N Engl J Med. 2009 Nov 5;361(19):1838-47. doi: 10.1056/NEJMoa0810097.

48.

Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.

van Stipdonk MJ, Badia-Martinez D, Sluijter M, Offringa R, van Hall T, Achour A.

Cancer Res. 2009 Oct 1;69(19):7784-92. doi: 10.1158/0008-5472.CAN-09-1724. Epub 2009 Sep 29.

49.

A regulated auxin minimum is required for seed dispersal in Arabidopsis.

Sorefan K, Girin T, Liljegren SJ, Ljung K, Robles P, Galván-Ampudia CS, Offringa R, Friml J, Yanofsky MF, Østergaard L.

Nature. 2009 May 28;459(7246):583-6. doi: 10.1038/nature07875.

PMID:
19478783
50.

Auxin-induced, SCF(TIR1)-mediated poly-ubiquitination marks AUX/IAA proteins for degradation.

Maraschin Fdos S, Memelink J, Offringa R.

Plant J. 2009 Jul;59(1):100-9. doi: 10.1111/j.1365-313X.2009.03854.x. Epub 2009 Feb 26.

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