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Items: 38

1.

Microbiota stratification identifies disease-specific alterations in neuro-Behçet's disease and multiple sclerosis.

Oezguen N, Yalcinkaya N, Kücükali CI, Dahdouli M, Hollister EB, Luna RA, Türkoglu R, Kürtüncü M, Eraksoy M, Savidge TC, Tüzün E.

Clin Exp Rheumatol. 2019 May 30. [Epub ahead of print]

PMID:
31172918
2.

Leveraging Human Microbiome Features to Diagnose and Stratify Children with Irritable Bowel Syndrome.

Hollister EB, Oezguen N, Chumpitazi BP, Luna RA, Weidler EM, Rubio-Gonzales M, Dahdouli M, Cope JL, Mistretta TA, Raza S, Metcalf GA, Muzny DM, Gibbs RA, Petrosino JF, Heitkemper M, Savidge TC, Shulman RJ, Versalovic J.

J Mol Diagn. 2019 May;21(3):449-461. doi: 10.1016/j.jmoldx.2019.01.006. Epub 2019 Apr 17.

3.

Next-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis.

Spinler JK, Auchtung J, Brown A, Boonma P, Oezguen N, Ross CL, Luna RA, Runge J, Versalovic J, Peniche A, Dann SM, Britton RA, Haag A, Savidge TC.

Infect Immun. 2017 Sep 20;85(10). pii: e00303-17. doi: 10.1128/IAI.00303-17. Print 2017 Oct.

4.

Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome.

Labus JS, Hollister EB, Jacobs J, Kirbach K, Oezguen N, Gupta A, Acosta J, Luna RA, Aagaard K, Versalovic J, Savidge T, Hsiao E, Tillisch K, Mayer EA.

Microbiome. 2017 May 1;5(1):49. doi: 10.1186/s40168-017-0260-z.

5.

Distinct Microbiome-Neuroimmune Signatures Correlate With Functional Abdominal Pain in Children With Autism Spectrum Disorder.

Luna RA, Oezguen N, Balderas M, Venkatachalam A, Runge JK, Versalovic J, Veenstra-VanderWeele J, Anderson GM, Savidge T, Williams KC.

Cell Mol Gastroenterol Hepatol. 2016 Dec 11;3(2):218-230. doi: 10.1016/j.jcmgh.2016.11.008. eCollection 2017 Mar.

6.

GABA-producing Bifidobacterium dentium modulates visceral sensitivity in the intestine.

Pokusaeva K, Johnson C, Luk B, Uribe G, Fu Y, Oezguen N, Matsunami RK, Lugo M, Major A, Mori-Akiyama Y, Hollister EB, Dann SM, Shi XZ, Engler DA, Savidge T, Versalovic J.

Neurogastroenterol Motil. 2017 Jan;29(1). doi: 10.1111/nmo.12904. Epub 2016 Jul 25.

7.

Regulation of protein-ligand binding affinity by hydrogen bond pairing.

Chen D, Oezguen N, Urvil P, Ferguson C, Dann SM, Savidge TC.

Sci Adv. 2016 Mar 25;2(3):e1501240. doi: 10.1126/sciadv.1501240. eCollection 2016 Mar.

8.

Relating tribological stimuli to somatosensory electroencephalographic responses.

Oezguen N, Schubert KJ, Bergmann R, Bennewitz R, Strauss DJ.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:8115-8. doi: 10.1109/EMBC.2015.7320277.

PMID:
26738177
9.

Allele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors.

Joffré E, von Mentzer A, Abd El Ghany M, Oezguen N, Savidge T, Dougan G, Svennerholm AM, Sjöling Å.

J Bacteriol. 2015 Jan;197(2):392-403. doi: 10.1128/JB.02050-14. Epub 2014 Nov 17.

10.

Critical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis.

Li S, Shi L, Yang Z, Zhang Y, Perez-Cordon G, Huang T, Ramsey J, Oezguen N, Savidge TC, Feng H.

Infect Immun. 2015 Feb;83(2):502-13. doi: 10.1128/IAI.02316-14. Epub 2014 Nov 17.

11.

Nuclear trafficking of the HIV-1 pre-integration complex depends on the ADAM10 intracellular domain.

Endsley MA, Somasunderam AD, Li G, Oezguen N, Thiviyanathan V, Murray JL, Rubin DH, Hodge TW, O'Brien WA, Lewis B, Ferguson MR.

Virology. 2014 Apr;454-455:60-6. doi: 10.1016/j.virol.2014.02.006. Epub 2014 Feb 22.

12.

Gut microbiota influences low fermentable substrate diet efficacy in children with irritable bowel syndrome.

Chumpitazi BP, Hollister EB, Oezguen N, Tsai CM, McMeans AR, Luna RA, Savidge TC, Versalovic J, Shulman RJ.

Gut Microbes. 2014 Mar-Apr;5(2):165-75. doi: 10.4161/gmic.27923. Epub 2014 Jan 27.

13.

The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions.

Hegde ML, Tsutakawa SE, Hegde PM, Holthauzen LM, Li J, Oezguen N, Hilser VJ, Tainer JA, Mitra S.

J Mol Biol. 2013 Jul 10;425(13):2359-71. doi: 10.1016/j.jmb.2013.03.030. Epub 2013 Mar 27.

14.

Base of the measles virus fusion trimer head receives the signal that triggers membrane fusion.

Apte-Sengupta S, Negi S, Leonard VH, Oezguen N, Navaratnarajah CK, Braun W, Cattaneo R.

J Biol Chem. 2012 Sep 21;287(39):33026-35. Epub 2012 Aug 2.

15.

Clostridial toxins: sensing a target in a hostile gut environment.

Oezguen N, Power TD, Urvil P, Feng H, Pothoulakis C, Stamler JS, Braun W, Savidge TC.

Gut Microbes. 2012 Jan-Feb;3(1):35-41. doi: 10.4161/gmic.19250. Epub 2012 Jan 1. Review.

16.

MD simulation and experimental evidence for Mg²+ binding at the B site in human AP endonuclease 1.

Oezguen N, Mantha AK, Izumi T, Schein CH, Mitra S, Braun W.

Bioinformation. 2011;7(4):184-98. Epub 2011 Oct 14.

17.

How cytokines co-occur across asthma patients: from bipartite network analysis to a molecular-based classification.

Bhavnani SK, Victor S, Calhoun WJ, Busse WW, Bleecker E, Castro M, Ju H, Pillai R, Oezguen N, Bellala G, Brasier AR.

J Biomed Inform. 2011 Dec;44 Suppl 1:S24-30. doi: 10.1016/j.jbi.2011.09.006. Epub 2011 Oct 1.

19.

Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins.

Savidge TC, Urvil P, Oezguen N, Ali K, Choudhury A, Acharya V, Pinchuk I, Torres AG, English RD, Wiktorowicz JE, Loeffelholz M, Kumar R, Shi L, Nie W, Braun W, Herman B, Hausladen A, Feng H, Stamler JS, Pothoulakis C.

Nat Med. 2011 Aug 21;17(9):1136-41. doi: 10.1038/nm.2405.

20.

The heads of the measles virus attachment protein move to transmit the fusion-triggering signal.

Navaratnarajah CK, Oezguen N, Rupp L, Kay L, Leonard VH, Braun W, Cattaneo R.

Nat Struct Mol Biol. 2011 Feb;18(2):128-34. doi: 10.1038/nsmb.1967. Epub 2011 Jan 9.

21.

NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU).

Schein CH, Oezguen N, van der Heden van Noort GJ, Filippov DV, Paul A, Kumar E, Braun W.

Peptides. 2010 Aug;31(8):1441-8. doi: 10.1016/j.peptides.2010.04.021. Epub 2010 May 2.

22.

Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection.

Kumar S, Qiu H, Oezguen N, Herlyn H, Halpert JR, Wojnowski L.

Drug Metab Dispos. 2009 Jun;37(6):1328-33. doi: 10.1124/dmd.108.024372. Epub 2009 Mar 19.

23.

Structural analysis of linear and conformational epitopes of allergens.

Ivanciuc O, Schein CH, Garcia T, Oezguen N, Negi SS, Braun W.

Regul Toxicol Pharmacol. 2009 Aug;54(3 Suppl):S11-9. doi: 10.1016/j.yrtph.2008.11.007. Epub 2008 Dec 14. Review.

24.

Comprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes.

Oezguen N, Zhou B, Negi SS, Ivanciuc O, Schein CH, Labesse G, Braun W.

Mol Immunol. 2008 Aug;45(14):3740-7. doi: 10.1016/j.molimm.2008.05.026. Epub 2008 Jul 14.

25.

Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed.

Leonard VH, Sinn PL, Hodge G, Miest T, Devaux P, Oezguen N, Braun W, McCray PB Jr, McChesney MB, Cattaneo R.

J Clin Invest. 2008 Jul;118(7):2448-58. doi: 10.1172/JCI35454.

26.

Identification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymes.

Oezguen N, Kumar S, Hindupur A, Braun W, Muralidhara BK, Halpert JR.

J Biol Chem. 2008 Aug 1;283(31):21808-16. doi: 10.1074/jbc.M708582200. Epub 2008 May 21.

27.

Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1.

Mantha AK, Oezguen N, Bhakat KK, Izumi T, Braun W, Mitra S.

J Mol Biol. 2008 May 23;379(1):28-37. doi: 10.1016/j.jmb.2008.03.052. Epub 2008 Apr 3.

28.

Dynamic interaction of the measles virus hemagglutinin with its receptor signaling lymphocytic activation molecule (SLAM, CD150).

Navaratnarajah CK, Vongpunsawad S, Oezguen N, Stehle T, Braun W, Hashiguchi T, Maenaka K, Yanagi Y, Cattaneo R.

J Biol Chem. 2008 Apr 25;283(17):11763-71. doi: 10.1074/jbc.M800896200. Epub 2008 Feb 21.

29.

InterProSurf: a web server for predicting interacting sites on protein surfaces.

Negi SS, Schein CH, Oezguen N, Power TD, Braun W.

Bioinformatics. 2007 Dec 15;23(24):3397-9. Epub 2007 Oct 12.

30.

A "moving metal mechanism" for substrate cleavage by the DNA repair endonuclease APE-1.

Oezguen N, Schein CH, Peddi SR, Power TD, Izumi T, Braun W.

Proteins. 2007 Jul 1;68(1):313-23.

PMID:
17427952
31.

NMR structure of the viral peptide linked to the genome (VPg) of poliovirus.

Schein CH, Oezguen N, Volk DE, Garimella R, Paul A, Braun W.

Peptides. 2006 Jul;27(7):1676-84. Epub 2006 Mar 15.

32.

Novel, structure-based mechanism for uridylylation of the genome-linked peptide (VPg) of picornaviruses.

Schein CH, Volk DE, Oezguen N, Paul A.

Proteins. 2006 Jun 1;63(4):719-26.

PMID:
16498624
33.

Nearby clusters of hemagglutinin residues sustain SLAM-dependent canine distemper virus entry in peripheral blood mononuclear cells.

von Messling V, Oezguen N, Zheng Q, Vongpunsawad S, Braun W, Cattaneo R.

J Virol. 2005 May;79(9):5857-62.

34.

Molego-based definition of the architecture and specificity of metal-binding sites.

Schein CH, Zhou B, Oezguen N, Mathura VS, Braun W.

Proteins. 2005 Jan 1;58(1):200-10.

PMID:
15505785
35.

Using property based sequence motifs and 3D modeling to determine structure and functional regions of proteins.

Ivanciuc O, Oezguen N, Mathura VS, Schein CH, Xu Y, Braun W.

Curr Med Chem. 2004 Mar;11(5):583-93. Review.

PMID:
15032606
36.
37.

Membrane-protein interactions contribute to efficient 27-hydroxylation of cholesterol by mitochondrial cytochrome P450 27A1.

Murtazina D, Puchkaev AV, Schein CH, Oezguen N, Braun W, Nanavati A, Pikuleva IA.

J Biol Chem. 2002 Oct 4;277(40):37582-9. Epub 2002 Jul 17.

38.

Automated assignment and 3D structure calculations using combinations of 2D homonuclear and 3D heteronuclear NOESY spectra.

Oezguen N, Adamian L, Xu Y, Rajarathnam K, Braun W.

J Biomol NMR. 2002 Mar;22(3):249-63.

PMID:
11991354

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