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Items: 12

1.

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.

Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, Berghoff AS, Marsh K, Steadman M, Zhu D, Nicolay B, Wiestler B, Breckwoldt MO, Al-Ali R, Karcher-Bausch S, Bozza M, Oezen I, Kramer M, Meyer J, Habel A, Eisel J, Poschet G, Weller M, Preusser M, Nadji-Ohl M, Thon N, Burger MC, Harter PN, Ratliff M, Harbottle R, Benner A, Schrimpf D, Okun J, Herold-Mende C, Turcan S, Kaulfuss S, Hess-Stumpp H, Bieback K, Cahill DP, Plate KH, Hänggi D, Dorsch M, Suvà ML, Niemeyer BA, von Deimling A, Wick W, Platten M.

Nat Med. 2018 Jul 9. doi: 10.1038/s41591-018-0095-6. [Epub ahead of print]

PMID:
29988124
2.

Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.

Tykocinski LO, Lauffer AM, Bohnen A, Kaul NC, Krienke S, Tretter T, Adam I, Mohapatra SR, Saikali P, Löhning M, Neidhart M, Gay S, Oezen I, Platten M, Opitz CA, Lorenz HM.

J Immunol. 2017 Apr 15;198(8):3109-3117. doi: 10.4049/jimmunol.1600600. Epub 2017 Mar 6.

3.

General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation.

Keil M, Sonner JK, Lanz TV, Oezen I, Bunse T, Bittner S, Meyer HV, Meuth SG, Wick W, Platten M.

J Neuroimmunol. 2016 Aug 15;297:117-26. doi: 10.1016/j.jneuroim.2016.05.014. Epub 2016 May 20.

PMID:
27397084
4.

Cancer Immunotherapy by Targeting IDO1/TDO and Their Downstream Effectors.

Platten M, von Knebel Doeberitz N, Oezen I, Wick W, Ochs K.

Front Immunol. 2015 Jan 12;5:673. doi: 10.3389/fimmu.2014.00673. eCollection 2014. Review.

5.

Proximity ligation assay evaluates IDH1R132H presentation in gliomas.

Bunse L, Schumacher T, Sahm F, Pusch S, Oezen I, Rauschenbach K, Gonzalez M, Solecki G, Osswald M, Capper D, Wiestler B, Winkler F, Herold-Mende C, von Deimling A, Wick W, Platten M.

J Clin Invest. 2015 Feb;125(2):593-606. doi: 10.1172/JCI77780. Epub 2015 Jan 2.

6.

A vaccine targeting mutant IDH1 induces antitumour immunity.

Schumacher T, Bunse L, Pusch S, Sahm F, Wiestler B, Quandt J, Menn O, Osswald M, Oezen I, Ott M, Keil M, Balß J, Rauschenbach K, Grabowska AK, Vogler I, Diekmann J, Trautwein N, Eichmüller SB, Okun J, Stevanović S, Riemer AB, Sahin U, Friese MA, Beckhove P, von Deimling A, Wick W, Platten M.

Nature. 2014 Aug 21;512(7514):324-7. doi: 10.1038/nature13387. Epub 2014 Jun 25.

PMID:
25043048
7.

Myelin basic protein cleaves cell adhesion molecule L1 and promotes neuritogenesis and cell survival.

Lutz D, Loers G, Kleene R, Oezen I, Kataria H, Katagihallimath N, Braren I, Harauz G, Schachner M.

J Biol Chem. 2014 May 9;289(19):13503-18. doi: 10.1074/jbc.M113.530238. Epub 2014 Mar 26.

8.

Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma.

Ochs K, Sahm F, Opitz CA, Lanz TV, Oezen I, Couraud PO, von Deimling A, Wick W, Platten M.

J Neuroimmunol. 2013 Dec 15;265(1-2):106-16. doi: 10.1016/j.jneuroim.2013.09.011. Epub 2013 Sep 20.

PMID:
24090655
9.

The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress.

Sahm F, Oezen I, Opitz CA, Radlwimmer B, von Deimling A, Ahrendt T, Adams S, Bode HB, Guillemin GJ, Wick W, Platten M.

Cancer Res. 2013 Jun 1;73(11):3225-34. doi: 10.1158/0008-5472.CAN-12-3831. Epub 2013 Apr 2.

10.

Dermatan 4-O-sulfotransferase1 ablation accelerates peripheral nerve regeneration.

Akyüz N, Rost S, Mehanna A, Bian S, Loers G, Oezen I, Mishra B, Hoffmann K, Guseva D, Laczynska E, Irintchev A, Jakovcevski I, Schachner M.

Exp Neurol. 2013 Sep;247:517-30. doi: 10.1016/j.expneurol.2013.01.025. Epub 2013 Jan 27.

PMID:
23360803
11.

Distribution and cellular localization of adrenoleukodystrophy protein in human tissues: implications for X-linked adrenoleukodystrophy.

Höftberger R, Kunze M, Weinhofer I, Aboul-Enein F, Voigtländer T, Oezen I, Amann G, Bernheimer H, Budka H, Berger J.

Neurobiol Dis. 2007 Nov;28(2):165-74. Epub 2007 Aug 29.

PMID:
17761426
12.

Accumulation of very long-chain fatty acids does not affect mitochondrial function in adrenoleukodystrophy protein deficiency.

Oezen I, Rossmanith W, Forss-Petter S, Kemp S, Voigtländer T, Moser-Thier K, Wanders RJ, Bittner RE, Berger J.

Hum Mol Genet. 2005 May 1;14(9):1127-37. Epub 2005 Mar 16.

PMID:
15772093

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