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Items: 9


Mutant MRPS5 affects mitoribosomal accuracy and confers stress-related behavioral alterations.

Akbergenov R, Duscha S, Fritz AK, Juskeviciene R, Oishi N, Schmitt K, Shcherbakov D, Teo Y, Boukari H, Freihofer P, Isnard-Petit P, Oettinghaus B, Frank S, Thiam K, Rehrauer H, Westhof E, Schacht J, Eckert A, Wolfer D, Böttger EC.

EMBO Rep. 2018 Sep 20. pii: e46193. doi: 10.15252/embr.201846193. [Epub ahead of print]


Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21.

Restelli LM, Oettinghaus B, Halliday M, Agca C, Licci M, Sironi L, Savoia C, Hench J, Tolnay M, Neutzner A, Schmidt A, Eckert A, Mallucci G, Scorrano L, Frank S.

Cell Rep. 2018 Aug 7;24(6):1407-1414. doi: 10.1016/j.celrep.2018.07.023.


Circadian Control of DRP1 Activity Regulates Mitochondrial Dynamics and Bioenergetics.

Schmitt K, Grimm A, Dallmann R, Oettinghaus B, Restelli LM, Witzig M, Ishihara N, Mihara K, Ripperger JA, Albrecht U, Frank S, Brown SA, Eckert A.

Cell Metab. 2018 Mar 6;27(3):657-666.e5. doi: 10.1016/j.cmet.2018.01.011. Epub 2018 Feb 22.


DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress.

Oettinghaus B, D'Alonzo D, Barbieri E, Restelli LM, Savoia C, Licci M, Tolnay M, Frank S, Scorrano L.

Biochim Biophys Acta. 2016 Aug;1857(8):1267-1276. doi: 10.1016/j.bbabio.2016.03.016. Epub 2016 Mar 17.


Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons.

Oettinghaus B, Schulz JM, Restelli LM, Licci M, Savoia C, Schmidt A, Schmitt K, Grimm A, Morè L, Hench J, Tolnay M, Eckert A, D'Adamo P, Franken P, Ishihara N, Mihara K, Bischofberger J, Scorrano L, Frank S.

Cell Death Differ. 2016 Jan;23(1):18-28. doi: 10.1038/cdd.2015.39. Epub 2015 Apr 24.


Less than perfect divorces: dysregulated mitochondrial fission and neurodegeneration.

Oettinghaus B, Licci M, Scorrano L, Frank S.

Acta Neuropathol. 2012 Feb;123(2):189-203. doi: 10.1007/s00401-011-0930-z. Epub 2011 Dec 17. Review.


Apaf1 plays a pro-survival role by regulating centrosome morphology and function.

Ferraro E, Pesaresi MG, De Zio D, Cencioni MT, Gortat A, Cozzolino M, Berghella L, Salvatore AM, Oettinghaus B, Scorrano L, Pérez-Payà E, Cecconi F.

J Cell Sci. 2011 Oct 15;124(Pt 20):3450-63. doi: 10.1242/jcs.086298. Epub 2011 Oct 7.


Tonight, the same old, deadly programme: BH3-only proteins, mitochondria and yeast.

Oettinghaus B, Frank S, Scorrano L.

EMBO J. 2011 Jul 20;30(14):2754-6. doi: 10.1038/emboj.2011.220. No abstract available.


Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis.

Akshay S, Bertea M, Hobbie SN, Oettinghaus B, Shcherbakov D, Böttger EC, Akbergenov R.

Antimicrob Agents Chemother. 2011 Sep;55(9):4096-102. doi: 10.1128/AAC.01398-10. Epub 2011 Jul 5.

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