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Items: 1 to 50 of 84

1.

Defining certainty of net benefit: a GRADE concept paper.

Alper BS, Oettgen P, Kunnamo I, Iorio A, Ansari MT, Murad MH, Meerpohl JJ, Qaseem A, Hultcrantz M, Schünemann HJ, Guyatt G; GRADE Working Group.

BMJ Open. 2019 Jun 4;9(6):e027445. doi: 10.1136/bmjopen-2018-027445.

2.

Angiogenic patterning by STEEL, an endothelial-enriched long noncoding RNA.

Man HSJ, Sukumar AN, Lam GC, Turgeon PJ, Yan MS, Ku KH, Dubinsky MK, Ho JJD, Wang JJ, Das S, Mitchell N, Oettgen P, Sefton MV, Marsden PA.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2401-2406. doi: 10.1073/pnas.1715182115. Epub 2018 Feb 21.

3.

Epithelium-Specific ETS (ESE)-1 upregulated GP73 expression in hepatocellular carcinoma cells.

Wang F, Long Q, Gong Y, Hu L, Zhang H, Oettgen P, Peng T.

Cell Biosci. 2014 Dec 8;4(1):76. doi: 10.1186/2045-3701-4-76. eCollection 2014.

4.

Direct conversion of adult skin fibroblasts to endothelial cells by defined factors.

Han JK, Chang SH, Cho HJ, Choi SB, Ahn HS, Lee J, Jeong H, Youn SW, Lee HJ, Kwon YW, Cho HJ, Oh BH, Oettgen P, Park YB, Kim HS.

Circulation. 2014 Sep 30;130(14):1168-78. doi: 10.1161/CIRCULATIONAHA.113.007727. Epub 2014 Sep 3.

PMID:
25186941
5.

ETS factors regulate Vegf-dependent arterial specification.

Wythe JD, Dang LT, Devine WP, Boudreau E, Artap ST, He D, Schachterle W, Stainier DY, Oettgen P, Black BL, Bruneau BG, Fish JE.

Dev Cell. 2013 Jul 15;26(1):45-58. doi: 10.1016/j.devcel.2013.06.007. Epub 2013 Jul 3.

6.

TGF-β induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy.

Kato M, Dang V, Wang M, Park JT, Deshpande S, Kadam S, Mardiros A, Zhan Y, Oettgen P, Putta S, Yuan H, Lanting L, Natarajan R.

Sci Signal. 2013 Jun 4;6(278):ra43. doi: 10.1126/scisignal.2003389.

7.

Role of RNA splicing in mediating lineage-specific expression of the von Willebrand factor gene in the endothelium.

Yuan L, Janes L, Beeler D, Spokes KC, Smith J, Li D, Jaminet SC, Oettgen P, Aird WC.

Blood. 2013 May 23;121(21):4404-12. doi: 10.1182/blood-2012-12-473785. Epub 2013 Mar 25.

8.

A mechanistic role for DNA methylation in endothelial cell (EC)-enriched gene expression: relationship with DNA replication timing.

Shirodkar AV, St Bernard R, Gavryushova A, Kop A, Knight BJ, Yan MS, Man HS, Sud M, Hebbel RP, Oettgen P, Aird WC, Marsden PA.

Blood. 2013 Apr 25;121(17):3531-40. doi: 10.1182/blood-2013-01-479170. Epub 2013 Feb 28.

9.

Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.

Vijayaraj P, Le Bras A, Mitchell N, Kondo M, Juliao S, Wasserman M, Beeler D, Spokes K, Aird WC, Baldwin HS, Oettgen P.

Development. 2012 Nov;139(21):3973-85. doi: 10.1242/dev.081596. Epub 2012 Aug 29.

10.

ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene.

Yuan L, Le Bras A, Sacharidou A, Itagaki K, Zhan Y, Kondo M, Carman CV, Davis GE, Aird WC, Oettgen P.

J Biol Chem. 2012 Feb 24;287(9):6582-91. doi: 10.1074/jbc.M111.300236. Epub 2012 Jan 10.

11.

E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.

Otero M, Plumb DA, Tsuchimochi K, Dragomir CL, Hashimoto K, Peng H, Olivotto E, Bevilacqua M, Tan L, Yang Z, Zhan Y, Oettgen P, Li Y, Marcu KB, Goldring MB.

J Biol Chem. 2012 Jan 27;287(5):3559-72. doi: 10.1074/jbc.M111.265744. Epub 2011 Dec 9.

12.

RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG.

Yuan L, Sacharidou A, Stratman AN, Le Bras A, Zwiers PJ, Spokes K, Bhasin M, Shih SC, Nagy JA, Molema G, Aird WC, Davis GE, Oettgen P.

Blood. 2011 Jul 28;118(4):1145-53. doi: 10.1182/blood-2010-10-315275. Epub 2011 May 31.

13.

Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle.

Liu J, Yuan L, Molema G, Regan E, Janes L, Beeler D, Spokes KC, Okada Y, Minami T, Oettgen P, Aird WC.

Blood. 2011 Jan 6;117(1):342-51. doi: 10.1182/blood-2010-06-287987. Epub 2010 Oct 27.

14.

CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease.

Castellani RJ, Nugent SL, Morrison AL, Zhu X, Lee HG, Harris PL, Bajić V, Sharma HS, Chen SG, Oettgen P, Perry G, Smith MA.

J Neural Transm (Vienna). 2011 Jan;118(1):23-6. doi: 10.1007/s00702-010-0485-5. Epub 2010 Oct 24.

15.

The counter-regulatory effects of ESE-1 during angiotensin II-mediated vascular inflammation and remodeling.

Zhan Y, Yuan L, Kondo M, Oettgen P.

Am J Hypertens. 2010 Dec;23(12):1312-7. doi: 10.1038/ajh.2010.164. Epub 2010 Aug 5.

16.

Ets-1 and Ets-2 regulate the expression of microRNA-126 in endothelial cells.

Harris TA, Yamakuchi M, Kondo M, Oettgen P, Lowenstein CJ.

Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):1990-7. doi: 10.1161/ATVBAHA.110.211706. Epub 2010 Jul 29.

17.

Molecular mechanisms of endothelial differentiation.

Le Bras A, Vijayaraj P, Oettgen P.

Vasc Med. 2010 Aug;15(4):321-31. doi: 10.1177/1358863X10371685. Epub 2010 Jul 9. Review.

PMID:
20621955
18.

Bioinformatic identification and characterization of human endothelial cell-restricted genes.

Bhasin M, Yuan L, Keskin DB, Otu HH, Libermann TA, Oettgen P.

BMC Genomics. 2010 May 28;11:342. doi: 10.1186/1471-2164-11-342.

19.

The role of ets factors in tumor angiogenesis.

Oettgen P.

J Oncol. 2010;2010:767384. doi: 10.1155/2010/767384. Epub 2010 May 4.

20.

ERG is required for the differentiation of embryonic stem cells along the endothelial lineage.

Nikolova-Krstevski V, Yuan L, Le Bras A, Vijayaraj P, Kondo M, Gebauer I, Bhasin M, Carman CV, Oettgen P.

BMC Dev Biol. 2009 Dec 23;9:72. doi: 10.1186/1471-213X-9-72.

21.

Differential roles for ETS, CREB, and EGR binding sites in mediating VEGF receptor 1 expression in vivo.

Jin E, Liu J, Suehiro J, Yuan L, Okada Y, Nikolova-Krstevski V, Yano K, Janes L, Beeler D, Spokes KC, Li D, Regan E, Shih SC, Oettgen P, Minami T, Aird WC.

Blood. 2009 Dec 24;114(27):5557-66. doi: 10.1182/blood-2009-05-220434. Epub 2009 Oct 12.

22.

Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.

Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T.

J Biol Chem. 2009 Oct 16;284(42):29109-24. doi: 10.1074/jbc.M109.041145. Epub 2009 Aug 12.

23.

Functional redundancy of Ets1 and Ets2.

Oettgen P.

Blood. 2009 Jul 30;114(5):934-5. doi: 10.1182/blood-2009-05-221812. No abstract available.

24.

Alterations in transcriptional responses associated with vascular aging.

Zhan Y, Yuan L, Oettgen P.

J Inflamm (Lond). 2009 May 21;6:16. doi: 10.1186/1476-9255-6-16.

25.

Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene.

Yuan L, Nikolova-Krstevski V, Zhan Y, Kondo M, Bhasin M, Varghese L, Yano K, Carman CV, Aird WC, Oettgen P.

Circ Res. 2009 May 8;104(9):1049-57. doi: 10.1161/CIRCRESAHA.108.190751. Epub 2009 Apr 9.

26.

Mechanism of inhibition of tumor angiogenesis by beta-hydroxyisovalerylshikonin.

Komi Y, Suzuki Y, Shimamura M, Kajimoto S, Nakajo S, Masuda M, Shibuya M, Itabe H, Shimokado K, Oettgen P, Nakaya K, Kojima S.

Cancer Sci. 2009 Feb;100(2):269-77. doi: 10.1111/j.1349-7006.2008.01049.x.

27.

Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells.

Melero-Martin JM, De Obaldia ME, Kang SY, Khan ZA, Yuan L, Oettgen P, Bischoff J.

Circ Res. 2008 Jul 18;103(2):194-202. doi: 10.1161/CIRCRESAHA.108.178590. Epub 2008 Jun 12.

28.

A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.

Okada Y, Jin E, Nikolova-Krstevski V, Yano K, Liu J, Beeler D, Spokes K, Kitayama M, Funahashi N, Doi T, Janes L, Minami T, Oettgen P, Aird WC.

Blood. 2008 Sep 15;112(6):2336-9. doi: 10.1182/blood-2008-01-135079. Epub 2008 Jun 2.

29.

Gene expression analysis of embryonic stem cells expressing VE-cadherin (CD144) during endothelial differentiation.

Nikolova-Krstevski V, Bhasin M, Otu HH, Libermann T, Oettgen P.

BMC Genomics. 2008 May 22;9:240. doi: 10.1186/1471-2164-9-240.

30.

ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes.

Peng H, Tan L, Osaki M, Zhan Y, Ijiri K, Tsuchimochi K, Otero M, Wang H, Choy BK, Grall FT, Gu X, Libermann TA, Oettgen P, Goldring MB.

J Cell Physiol. 2008 May;215(2):562-73.

31.

Ets-1 is a critical transcriptional regulator of reactive oxygen species and p47(phox) gene expression in response to angiotensin II.

Ni W, Zhan Y, He H, Maynard E, Balschi JA, Oettgen P.

Circ Res. 2007 Nov 9;101(10):985-94. Epub 2007 Sep 13.

PMID:
17872466
32.

A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.

Okada Y, Yano K, Jin E, Funahashi N, Kitayama M, Doi T, Spokes K, Beeler DL, Shih SC, Okada H, Danilov TA, Maynard E, Minami T, Oettgen P, Aird WC.

Circ Res. 2007 Jun 22;100(12):1712-22. Epub 2007 May 10.

PMID:
17495228
33.

Antiapoptotic effect of implanted embryonic stem cell-derived early-differentiated cells in aging rats after myocardial infarction.

Xiang M, Wang J, Kaplan E, Oettgen P, Lipsitz L, Morgan JP, Min JY.

J Gerontol A Biol Sci Med Sci. 2006 Dec;61(12):1219-27.

34.

Regulation of vascular inflammation and remodeling by ETS factors.

Oettgen P.

Circ Res. 2006 Nov 24;99(11):1159-66. Review.

PMID:
17122446
35.

Which lipid measures are prognostic indicators of cardiovascular disease in women?

Oettgen P.

Nat Clin Pract Endocrinol Metab. 2006 Apr;2(4):190-1. No abstract available.

PMID:
16932280
36.

Cardiac Stem Cell Therapy. Need for Optimization of Efficacy and Safety Monitoring.

Oettgen P, Boyle AJ, Schulman SP, Hare JM.

Circulation. 2006 Jul 25;114(4):353-8. Review. No abstract available.

PMID:
16864740
37.

Is stem cell therapy ready for patients? Stem Cell Therapy for Cardiac Repair. Ready for the Next Step .

Boyle AJ, Schulman SP, Hare JM, Oettgen P.

Circulation. 2006 Jul 25;114(4):339-52. Review. No abstract available.

PMID:
16864739
38.

Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma.

Bellovin DI, Simpson KJ, Danilov T, Maynard E, Rimm DL, Oettgen P, Mercurio AM.

Oncogene. 2006 Nov 2;25(52):6959-67. Epub 2006 May 22.

PMID:
16715134
39.

Homing of intravenously infused embryonic stem cell-derived cells to injured hearts after myocardial infarction.

Min JY, Huang X, Xiang M, Meissner A, Chen Y, Ke Q, Kaplan E, Rana JS, Oettgen P, Morgan JP.

J Thorac Cardiovasc Surg. 2006 Apr;131(4):889-97.

40.

Critical role for the Ets transcription factor ELF-1 in the development of tumor angiogenesis.

Huang X, Brown C, Ni W, Maynard E, Rigby AC, Oettgen P.

Blood. 2006 Apr 15;107(8):3153-60. Epub 2005 Dec 13.

41.

A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation.

Ijiri K, Zerbini LF, Peng H, Correa RG, Lu B, Walsh N, Zhao Y, Taniguchi N, Huang XL, Otu H, Wang H, Wang JF, Komiya S, Ducy P, Rahman MU, Flavell RA, Gravallese EM, Oettgen P, Libermann TA, Goldring MB.

J Biol Chem. 2005 Nov 18;280(46):38544-55. Epub 2005 Sep 2.

42.

Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling.

Zhan Y, Brown C, Maynard E, Anshelevich A, Ni W, Ho IC, Oettgen P.

J Clin Invest. 2005 Sep;115(9):2508-16.

43.

The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes.

Grall FT, Prall WC, Wei W, Gu X, Cho JY, Choy BK, Zerbini LF, Inan MS, Goldring SR, Gravallese EM, Goldring MB, Oettgen P, Libermann TA.

FEBS J. 2005 Apr;272(7):1676-87.

44.

Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma.

Bates RC, Bellovin DI, Brown C, Maynard E, Wu B, Kawakatsu H, Sheppard D, Oettgen P, Mercurio AM.

J Clin Invest. 2005 Feb;115(2):339-47.

45.

In vivo MRI of embryonic stem cells in a mouse model of myocardial infarction.

Himes N, Min JY, Lee R, Brown C, Shea J, Huang X, Xiao YF, Morgan JP, Burstein D, Oettgen P.

Magn Reson Med. 2004 Nov;52(5):1214-9.

46.

Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.

Wang H, Fang R, Cho JY, Libermann TA, Oettgen P.

J Biol Chem. 2004 Jun 11;279(24):25241-50. Epub 2004 Apr 8.

47.

RTEF-1, a novel transcriptional stimulator of vascular endothelial growth factor in hypoxic endothelial cells.

Shie JL, Wu G, Wu J, Liu FF, Laham RJ, Oettgen P, Li J.

J Biol Chem. 2004 Jun 11;279(24):25010-6. Epub 2004 Apr 8.

48.

Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene.

Cho JY, Akbarali Y, Zerbini LF, Gu X, Boltax J, Wang Y, Oettgen P, Zhang DE, Libermann TA.

J Biol Chem. 2004 May 7;279(19):19512-22. Epub 2004 Feb 17.

49.

ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation.

Brown C, Gaspar J, Pettit A, Lee R, Gu X, Wang H, Manning C, Voland C, Goldring SR, Goldring MB, Libermann TA, Gravallese EM, Oettgen P.

J Biol Chem. 2004 Mar 26;279(13):12794-803. Epub 2004 Jan 8.

50.

Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids.

Bates RC, Goldsmith JD, Bachelder RE, Brown C, Shibuya M, Oettgen P, Mercurio AM.

Curr Biol. 2003 Sep 30;13(19):1721-7.

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