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Items: 37

1.

Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy.

Morhenn K, Quentin T, Wichmann H, Steinmetz M, Prondzynski M, Söhren KD, Christ T, Geertz B, Schröder S, Schöndube FA, Hasenfuss G, Schlossarek S, Zimmermann WH, Carrier L, Eschenhagen T, Cardinaux JR, Lutz S, Oetjen E.

J Mol Cell Cardiol. 2019 Feb;127:31-43. doi: 10.1016/j.yjmcc.2018.12.001. Epub 2018 Dec 4.

PMID:
30521840
2.

TNFα-induced DLK activation contributes to apoptosis in the beta-cell line HIT.

Börchers S, Babaei R, Klimpel C, Duque Escobar J, Schröder S, Blume R, Malik MNH, Oetjen E.

Naunyn Schmiedebergs Arch Pharmacol. 2017 Aug;390(8):813-825. doi: 10.1007/s00210-017-1385-0. Epub 2017 May 27.

PMID:
28550372
3.

Endothelial cells regulate β-catenin activity in adrenocortical cells via secretion of basic fibroblast growth factor.

Schwafertz C, Schinner S, Kühn MC, Haase M, Asmus A, Mülders-Opgenoorth B, Ansurudeen I, Hornsby PJ, Morawietz H, Oetjen E, Schott M, Willenberg HS.

Mol Cell Endocrinol. 2017 Feb 5;441:108-115. doi: 10.1016/j.mce.2016.11.015. Epub 2016 Nov 23.

PMID:
27889473
4.

Regulation of Beta-Cell Function and Mass by the Dual Leucine Zipper Kinase.

Oetjen E.

Arch Pharm (Weinheim). 2016 Jun;349(6):410-3. doi: 10.1002/ardp.201600053. Epub 2016 Apr 21. Review.

PMID:
27100796
5.

Dual leucine zipper kinase (MAP3K12) modulators: a patent review (2010-2015).

Oetjen E, Lemcke T.

Expert Opin Ther Pat. 2016 May;26(5):607-16. doi: 10.1517/13543776.2016.1170810. Epub 2016 Apr 6. Review.

PMID:
27043251
6.

Distinct functions of the dual leucine zipper kinase depending on its subcellular localization.

Wallbach M, Duque Escobar J, Babaeikelishomi R, Stahnke MJ, Blume R, Schröder S, Kruegel J, Maedler K, Kluth O, Kehlenbach RH, Miosge N, Oetjen E.

Cell Signal. 2016 Apr;28(4):272-83. doi: 10.1016/j.cellsig.2016.01.002. Epub 2016 Jan 9.

PMID:
26776303
7.

Inhibition of human insulin gene transcription and MafA transcriptional activity by the dual leucine zipper kinase.

Stahnke MJ, Dickel C, Schröder S, Kaiser D, Blume R, Stein R, Pouponnot C, Oetjen E.

Cell Signal. 2014 Sep;26(9):1792-9. doi: 10.1016/j.cellsig.2014.04.006. Epub 2014 Apr 12.

8.

Something old, something new and something very old: drugs for treating type 2 diabetes.

Kaiser D, Oetjen E.

Br J Pharmacol. 2014 Jun;171(12):2940-50. doi: 10.1111/bph.12624. Review.

9.

Lithium enhances CRTC oligomer formation and the interaction between the CREB coactivators CRTC and CBP--implications for CREB-dependent gene transcription.

Heinrich A, von der Heyde AS, Böer U, Phu do T, Tzvetkov M, Oetjen E.

Cell Signal. 2013 Jan;25(1):113-25. doi: 10.1016/j.cellsig.2012.09.016. Epub 2012 Sep 18.

PMID:
23000340
10.

Cyclosporin A, but not everolimus, inhibits DNA repair mediated by calcineurin: implications for tumorigenesis under immunosuppression.

Thoms KM, Kuschal C, Oetjen E, Mori T, Kobayashi N, Laspe P, Boeckmann L, Schön MP, Emmert S.

Exp Dermatol. 2011 Mar;20(3):232-6. doi: 10.1111/j.1600-0625.2010.01213.x.

PMID:
21323745
11.

Regulation of the CREB coactivator TORC by the dual leucine zipper kinase at different levels.

Phu do T, Wallbach M, Depatie C, Fu A, Screaton RA, Oetjen E.

Cell Signal. 2011 Feb;23(2):344-53. doi: 10.1016/j.cellsig.2010.10.001. Epub 2010 Oct 19.

PMID:
20940047
12.

Inhibition of human insulin gene transcription by peroxisome proliferator-activated receptor gamma and thiazolidinedione oral antidiabetic drugs.

Schinner S, Krätzner R, Baun D, Dickel C, Blume R, Oetjen E.

Br J Pharmacol. 2009 Jul;157(5):736-45. doi: 10.1111/j.1476-5381.2009.00208.x. Epub 2009 Mar 26.

13.

Loss of insulin-induced inhibition of glucagon gene transcription in hamster pancreatic islet alpha cells by long-term insulin exposure.

González M, Böer U, Dickel C, Quentin T, Cierny I, Oetjen E, Knepel W.

Diabetologia. 2008 Nov;51(11):2012-21. doi: 10.1007/s00125-008-1134-5. Epub 2008 Sep 2.

PMID:
18762908
14.

Stimulation by lithium of the interaction between the transcription factor CREB and its co-activator TORC.

Heinrich A, Böer U, Tzvetkov M, Oetjen E, Knepel W.

Biosci Rep. 2009 Apr;29(2):77-87. doi: 10.1042/BSR20080116.

15.

Functional characterization of a -100_-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene.

Meineke C, Tzvetkov MV, Bokelmann K, Oetjen E, Hirsch-Ernst K, Kaiser R, Brockmöller J.

Pharmacogenet Genomics. 2008 Mar;18(3):219-30. doi: 10.1097/FPC.0b013e3282f51092.

PMID:
18300944
16.

Activation of the dual-leucine-zipper-bearing kinase and induction of beta-cell apoptosis by the immunosuppressive drug cyclosporin A.

Plaumann S, Blume R, Börchers S, Steinfelder HJ, Knepel W, Oetjen E.

Mol Pharmacol. 2008 Mar;73(3):652-9. Epub 2007 Nov 27.

PMID:
18042735
17.

A peroxisome proliferator-activated receptor gamma-retinoid X receptor heterodimer physically interacts with the transcriptional activator PAX6 to inhibit glucagon gene transcription.

Krätzner R, Fröhlich F, Lepler K, Schröder M, Röher K, Dickel C, Tzvetkov MV, Quentin T, Oetjen E, Knepel W.

Mol Pharmacol. 2008 Feb;73(2):509-17. Epub 2007 Oct 25.

PMID:
17962386
18.

Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1beta and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cells.

Oetjen E, Blume R, Cierny I, Schlag C, Kutschenko A, Krätzner R, Stein R, Knepel W.

Diabetologia. 2007 Aug;50(8):1678-87. Epub 2007 Jun 22.

PMID:
17583797
19.

Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine.

Tzvetkov MV, Meineke C, Oetjen E, Hirsch-Ernst K, Brockmöller J.

Gene. 2007 Jan 15;386(1-2):52-62. Epub 2006 Aug 23.

PMID:
17010535
20.

The role of prostaglandin E receptor-dependent signaling via cAMP in Mdr1b gene activation in primary rat hepatocyte cultures.

Ziemann C, Riecke A, Rüdell G, Oetjen E, Steinfelder HJ, Lass C, Kahl GF, Hirsch-Ernst KI.

J Pharmacol Exp Ther. 2006 Apr;317(1):378-86. Epub 2006 Jan 13.

PMID:
16415092
21.
22.

Characterization of a novel Foxa (hepatocyte nuclear factor-3) site in the glucagon promoter that is conserved between rodents and humans.

Sharma SK, Leinemann U, Ratke R, Oetjen E, Blume R, Dickel C, Knepel W.

Biochem J. 2005 Aug 1;389(Pt 3):831-41.

23.
24.

Protein kinase B activity is sufficient to mimic the effect of insulin on glucagon gene transcription.

Schinner S, Barthel A, Dellas C, Grzeskowiak R, Sharma SK, Oetjen E, Blume R, Knepel W.

J Biol Chem. 2005 Feb 25;280(8):7369-76. Epub 2004 Dec 7.

25.

Inhibition of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus in primary, mature islets of transgenic mice.

Oetjen E, Baun D, Beimesche S, Krause D, Cierny I, Blume R, Dickel C, Wehner S, Knepel W.

Mol Pharmacol. 2003 Jun;63(6):1289-95.

PMID:
12761338
26.

Regulation of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus at concentrations that inhibit calcineurin activity and involving the transcription factor CREB.

Oetjen E, Grapentin D, Blume R, Seeger M, Krause D, Eggers A, Knepel W.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Mar;367(3):227-36. Epub 2003 Feb 20.

PMID:
12644894
28.
30.

Identification and expression of a novel isoform of cAMP response element modulator in the human heart.

Müller FU, Bokník P, Knapp J, Neumann J, Vahlensieck U, Oetjen E, Scheld HH, Schmitz W.

FASEB J. 1998 Sep;12(12):1191-9.

PMID:
9737722
31.

Inhibition of CREB- and cAMP response element-mediated gene transcription by the immunosuppressive drugs cyclosporin A and FK506 in T cells.

Krüger M, Schwaninger M, Blume R, Oetjen E, Knepel W.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Oct;356(4):433-40.

PMID:
9349628
32.

Involvement of the Ca(2+)-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements.

Schwaninger M, Blume R, Krüger M, Lux G, Oetjen E, Knepel W.

J Biol Chem. 1995 Apr 14;270(15):8860-6.

33.

Distinct properties of the cAMP-responsive element of the rat insulin I gene.

Oetjen E, Diedrich T, Eggers A, Eckert B, Knepel W.

J Biol Chem. 1994 Oct 28;269(43):27036-44.

34.

Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization.

Schwaninger M, Blume R, Oetjen E, Lux G, Knepel W.

J Biol Chem. 1993 Nov 5;268(31):23111-5.

35.
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