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Items: 29


IL-12 signaling drives the differentiation and function of a TH1-derived TFH1-like cell population.

Powell MD, Read KA, Sreekumar BK, Jones DM, Oestreich KJ.

Sci Rep. 2019 Sep 30;9(1):13991. doi: 10.1038/s41598-019-50614-1.


Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-TFH cells.

Papillion A, Powell MD, Chisolm DA, Bachus H, Fuller MJ, Weinmann AS, Villarino A, O'Shea JJ, León B, Oestreich KJ, Ballesteros-Tato A.

Sci Immunol. 2019 Sep 13;4(39). pii: eaaw7636. doi: 10.1126/sciimmunol.aaw7636.


Ikaros Zinc Finger Transcription Factors: Regulators of Cytokine Signaling Pathways and CD4+ T Helper Cell Differentiation.

Powell MD, Read KA, Sreekumar BK, Oestreich KJ.

Front Immunol. 2019 Jun 6;10:1299. doi: 10.3389/fimmu.2019.01299. eCollection 2019. Review.


High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity.

Ringel-Scaia VM, Beitel-White N, Lorenzo MF, Brock RM, Huie KE, Coutermarsh-Ott S, Eden K, McDaniel DK, Verbridge SS, Rossmeisl JH Jr, Oestreich KJ, Davalos RV, Allen IC.

EBioMedicine. 2019 Jun;44:112-125. doi: 10.1016/j.ebiom.2019.05.036. Epub 2019 May 23.


Systemic Listeria monocytogenes Infection as a Model to Study T Helper Cell Immune Responses.

Ringel-Scaia VM, Powell MD, Read KA, Allen IC, Oestreich KJ.

Methods Mol Biol. 2019;1960:149-160. doi: 10.1007/978-1-4939-9167-9_13.


In Vitro Differentiation of Effector CD4+ T Helper Cell Subsets.

Read KA, Powell MD, Sreekumar BK, Oestreich KJ.

Methods Mol Biol. 2019;1960:75-84. doi: 10.1007/978-1-4939-9167-9_6.


Additive manufacturing of three-dimensional (3D) microfluidic-based microelectromechanical systems (MEMS) for acoustofluidic applications.

Cesewski E, Haring AP, Tong Y, Singh M, Thakur R, Laheri S, Read KA, Powell MD, Oestreich KJ, Johnson BN.

Lab Chip. 2018 Jul 10;18(14):2087-2098. doi: 10.1039/c8lc00427g.


Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells.

Read KA, Powell MD, Baker CE, Sreekumar BK, Ringel-Scaia VM, Bachus H, Martin RE, Cooley ID, Allen IC, Ballesteros-Tato A, Oestreich KJ.

J Immunol. 2017 Oct 1;199(7):2377-2387. doi: 10.4049/jimmunol.1700106. Epub 2017 Aug 28.


Control of lupus nephritis by changes of gut microbiota.

Mu Q, Zhang H, Liao X, Lin K, Liu H, Edwards MR, Ahmed SA, Yuan R, Li L, Cecere TE, Branson DB, Kirby JL, Goswami P, Leeth CM, Read KA, Oestreich KJ, Vieson MD, Reilly CM, Luo XM.

Microbiome. 2017 Jul 11;5(1):73. doi: 10.1186/s40168-017-0300-8.


TIPS pentacene loaded PEO-PDLLA core-shell nanoparticles have similar cellular uptake dynamics in M1 and M2 macrophages and in corresponding in vivo microenvironments.

McDaniel DK, Jo A, Ringel-Scaia VM, Coutermarsh-Ott S, Rothschild DE, Powell MD, Zhang R, Long TE, Oestreich KJ, Riffle JS, Davis RM, Allen IC.

Nanomedicine. 2017 Apr;13(3):1255-1266. doi: 10.1016/j.nano.2016.12.015. Epub 2016 Dec 29.


T follicular helper cell programming by cytokine-mediated events.

Read KA, Powell MD, Oestreich KJ.

Immunology. 2016 Nov;149(3):253-261. doi: 10.1111/imm.12648. Epub 2016 Aug 16. Review.


IL-2, IL-7, and IL-15: Multistage regulators of CD4(+) T helper cell differentiation.

Read KA, Powell MD, McDonald PW, Oestreich KJ.

Exp Hematol. 2016 Sep;44(9):799-808. doi: 10.1016/j.exphem.2016.06.003. Epub 2016 Jul 15. Review.


IL-7 signalling represses Bcl-6 and the TFH gene program.

McDonald PW, Read KA, Baker CE, Anderson AE, Powell MD, Ballesteros-Tato A, Oestreich KJ.

Nat Commun. 2016 Jan 8;7:10285. doi: 10.1038/ncomms10285.


Trans-presentation of IL-15 modulates STAT5 activation and Bcl-6 expression in TH1 cells.

Cooley ID, Read KA, Oestreich KJ.

Sci Rep. 2015 Oct 26;5:15722. doi: 10.1038/srep15722.


Bcl-6 directly represses the gene program of the glycolysis pathway.

Oestreich KJ, Read KA, Gilbertson SE, Hough KP, McDonald PW, Krishnamoorthy V, Weinmann AS.

Nat Immunol. 2014 Oct;15(10):957-64. doi: 10.1038/ni.2985. Epub 2014 Sep 7.


Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors.

Oestreich KJ, Weinmann AS.

Nat Rev Immunol. 2012 Nov;12(11):799-804. doi: 10.1038/nri3321. Epub 2012 Oct 12. Review.


Transcriptional mechanisms that regulate T helper 1 cell differentiation.

Oestreich KJ, Weinmann AS.

Curr Opin Immunol. 2012 Apr;24(2):191-5. doi: 10.1016/j.coi.2011.12.004. Epub 2012 Jan 10. Review.


Ikaros changes the face of NuRD remodeling.

Oestreich KJ, Weinmann AS.

Nat Immunol. 2011 Dec 16;13(1):16-8. doi: 10.1038/ni.2191. No abstract available.


T-bet employs diverse regulatory mechanisms to repress transcription.

Oestreich KJ, Weinmann AS.

Trends Immunol. 2012 Feb;33(2):78-83. doi: 10.1016/ Epub 2011 Nov 29. Review.


Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.

Youngblood B, Oestreich KJ, Ha SJ, Duraiswamy J, Akondy RS, West EE, Wei Z, Lu P, Austin JW, Riley JL, Boss JM, Ahmed R.

Immunity. 2011 Sep 23;35(3):400-12. doi: 10.1016/j.immuni.2011.06.015.


Encoding stability versus flexibility: lessons learned from examining epigenetics in T helper cell differentiation.

Oestreich KJ, Weinmann AS.

Curr Top Microbiol Immunol. 2012;356:145-64. doi: 10.1007/82_2011_141. Review.


Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.

Kao C, Oestreich KJ, Paley MA, Crawford A, Angelosanto JM, Ali MA, Intlekofer AM, Boss JM, Reiner SL, Weinmann AS, Wherry EJ.

Nat Immunol. 2011 May 29;12(7):663-71. doi: 10.1038/ni.2046.


The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns.

Oestreich KJ, Huang AC, Weinmann AS.

J Exp Med. 2011 May 9;208(5):1001-13. doi: 10.1084/jem.20102144. Epub 2011 Apr 25.


Abasic sites and strand breaks in DNA cause transcriptional mutagenesis in Escherichia coli.

Clauson CL, Oestreich KJ, Austin JW, Doetsch PW.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3657-62. doi: 10.1073/pnas.0913191107. Epub 2010 Feb 8.


NFATc1 regulates PD-1 expression upon T cell activation.

Oestreich KJ, Yoon H, Ahmed R, Boss JM.

J Immunol. 2008 Oct 1;181(7):4832-9.


Essential function for SWI-SNF chromatin-remodeling complexes in the promoter-directed assembly of Tcrb genes.

Osipovich O, Cobb RM, Oestreich KJ, Pierce S, Ferrier P, Oltz EM.

Nat Immunol. 2007 Aug;8(8):809-16. Epub 2007 Jun 24.


Accessibility control of V(D)J recombination.

Cobb RM, Oestreich KJ, Osipovich OA, Oltz EM.

Adv Immunol. 2006;91:45-109. Review.


Regulation of TCRbeta gene assembly by a promoter/enhancer holocomplex.

Oestreich KJ, Cobb RM, Pierce S, Chen J, Ferrier P, Oltz EM.

Immunity. 2006 Apr;24(4):381-91.

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