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Items: 1 to 50 of 178

1.

Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors.

Zhu L, Narloch JL, Onkar S, Joy M, Broadwater G, Luedke C, Hall A, Kim R, Pogue-Geile K, Sammons S, Nayyar N, Chukwueke U, Brastianos PK, Anders CK, Soloff AC, Vignali DAA, Tseng GC, Emens LA, Lucas PC, Blackwell KL, Oesterreich S, Lee AV.

J Immunother Cancer. 2019 Oct 18;7(1):265. doi: 10.1186/s40425-019-0755-1.

2.

Sex-Specific Differences in HLA Antibodies after Pneumococcal Vaccination in Kidney Transplant Recipients.

Lindemann M, Oesterreich S, Wilde B, Eisenberger U, Muelling N, Horn PA, Heinemann FM, Witzke O.

Vaccines (Basel). 2019 Aug 6;7(3). pii: E84. doi: 10.3390/vaccines7030084.

3.

Preclinical safety evaluation of the aqueous extract from Mangifera indica Linn. (Anacardiaceae): genotoxic, clastogenic and cytotoxic assessment in experimental models of genotoxicity in rats to predict potential human risks.

Villas Boas GR, Rodrigues Lemos JM, de Oliveira MW, Dos Santos RC, Stefanello da Silveira AP, Bacha FB, Aguero Ito CN, Cornelius EB, Lima FB, Sachilarid Rodrigues AM, Costa NB, Bittencourt FF, Freitas de Lima F, Paes MM, Gubert P, Oesterreich SA.

J Ethnopharmacol. 2019 Oct 28;243:112086. doi: 10.1016/j.jep.2019.112086. Epub 2019 Jul 13.

PMID:
31310830
4.

FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype.

Levine KM, Priedigkeit N, Basudan A, Tasdemir N, Sikora MJ, Sokol ES, Hartmaier RJ, Ding K, Ahmad NZ, Watters RJ, Weiss KR, Blohmer JU, Denkert C, Machleidt A, Karsten MM, Boisen MM, Elishaev E, Lucas PC, Lee AV, Oesterreich S.

NPJ Breast Cancer. 2019 Jun 27;5:19. doi: 10.1038/s41523-019-0114-x. eCollection 2019.

5.

Frequent amplifications of ESR1, ERBB2 and MDM4 in primary invasive lobular breast carcinoma.

Cao L, Basudan A, Sikora MJ, Bahreini A, Tasdemir N, Levine KM, Jankowitz RC, McAuliffe PF, Dabbs D, Haupt S, Haupt Y, Lucas PC, Lee AV, Oesterreich S, Atkinson JM.

Cancer Lett. 2019 Oct 1;461:21-30. doi: 10.1016/j.canlet.2019.06.011. Epub 2019 Jun 20.

PMID:
31229512
6.

SNAIL is induced by tamoxifen and leads to growth inhibition in invasive lobular breast carcinoma.

Bossart EA, Tasdemir N, Sikora MJ, Bahreini A, Levine KM, Chen J, Basudan A, Jacobsen BM, Burns TF, Oesterreich S.

Breast Cancer Res Treat. 2019 Jun;175(2):327-337. doi: 10.1007/s10549-019-05161-8. Epub 2019 Feb 23.

PMID:
30798422
7.

Molecular aspects of depression: A review from neurobiology to treatment.

Villas Boas GR, Boerngen de Lacerda R, Paes MM, Gubert P, Almeida WLDC, Rescia VC, de Carvalho PMG, de Carvalho AAV, Oesterreich SA.

Eur J Pharmacol. 2019 May 15;851:99-121. doi: 10.1016/j.ejphar.2019.02.024. Epub 2019 Feb 15. Review.

PMID:
30776369
8.

Network-guided prediction of aromatase inhibitor response in breast cancer.

Ruffalo M, Thomas R, Chen J, Lee AV, Oesterreich S, Bar-Joseph Z.

PLoS Comput Biol. 2019 Feb 11;15(2):e1006730. doi: 10.1371/journal.pcbi.1006730. eCollection 2019 Feb.

9.

Targeted mutation detection in breast cancer using MammaSeq™.

Smith NG, Gyanchandani R, Shah OS, Gurda GT, Lucas PC, Hartmaier RJ, Brufsky AM, Puhalla S, Bahreini A, Kota K, Wald AI, Nikiforov YE, Nikiforova MN, Oesterreich S, Lee AV.

Breast Cancer Res. 2019 Feb 8;21(1):22. doi: 10.1186/s13058-019-1102-7.

10.

Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer.

Sokol ES, Feng YX, Jin DX, Basudan A, Lee AV, Atkinson JM, Chen J, Stephens PJ, Frampton GM, Gupta PB, Ross JS, Chung JH, Oesterreich S, Ali SM, Hartmaier RJ.

Ann Oncol. 2019 Jan 1;30(1):115-123. doi: 10.1093/annonc/mdy497.

11.

Frequent ESR1 and CDK Pathway Copy-Number Alterations in Metastatic Breast Cancer.

Basudan A, Priedigkeit N, Hartmaier RJ, Sokol ES, Bahreini A, Watters RJ, Boisen MM, Bhargava R, Weiss KR, Karsten MM, Denkert C, Blohmer JU, Leone JP, Hamilton RL, Brufsky AM, Elishaev E, Lucas PC, Lee AV, Oesterreich S.

Mol Cancer Res. 2019 Feb;17(2):457-468. doi: 10.1158/1541-7786.MCR-18-0946. Epub 2018 Oct 24.

PMID:
30355675
12.

Clustering of Excess Body Weight-Related Behaviors in a Sample of Brazilian Adolescents.

de Souza Dantas M, Dos Santos MC, Lopes LAF, Guedes DP, Guedes MRA, Oesterreich SA.

Nutrients. 2018 Oct 15;10(10). pii: E1505. doi: 10.3390/nu10101505.

13.

MetaOmics: analysis pipeline and browser-based software suite for transcriptomic meta-analysis.

Ma T, Huo Z, Kuo A, Zhu L, Fang Z, Zeng X, Lin CW, Liu S, Wang L, Liu P, Rahman T, Chang LC, Kim S, Li J, Park Y, Song C, Oesterreich S, Sibille E, Tseng GC.

Bioinformatics. 2019 May 1;35(9):1597-1599. doi: 10.1093/bioinformatics/bty825.

PMID:
30304367
14.

The Evolution of Estrogen Receptor Signaling in the Progression of Endometriosis to Endometriosis-Associated Ovarian Cancer.

Andersen CL, Boisen MM, Sikora MJ, Ma T, Tseng G, Suryawanshi S, Vlad A, Elishaev E, Edwards RP, Oesterreich S.

Horm Cancer. 2018 Dec;9(6):399-407. doi: 10.1007/s12672-018-0350-9. Epub 2018 Oct 9.

PMID:
30302736
15.

Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures.

Tasdemir N, Bossart EA, Li Z, Zhu L, Sikora MJ, Levine KM, Jacobsen BM, Tseng GC, Davidson NE, Oesterreich S.

Cancer Res. 2018 Nov 1;78(21):6209-6222. doi: 10.1158/0008-5472.CAN-18-1416. Epub 2018 Sep 18.

PMID:
30228172
16.

Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer.

Du T, Sikora MJ, Levine KM, Tasdemir N, Riggins RB, Wendell SG, Van Houten B, Oesterreich S.

Breast Cancer Res. 2018 Sep 4;20(1):106. doi: 10.1186/s13058-018-1041-8.

17.

Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade.

Qin Y, Vasilatos SN, Chen L, Wu H, Cao Z, Fu Y, Huang M, Vlad AM, Lu B, Oesterreich S, Davidson NE, Huang Y.

Oncogene. 2019 Jan;38(3):390-405. doi: 10.1038/s41388-018-0451-5. Epub 2018 Aug 15.

18.

Cytotoxic, genotoxic and mutagenic evaluation of Alibertia edulis (rich.) a. Rich. ex DC: an indigenous species from Brazil.

Tolouei SEL, Traesel GK, Freitas de Lima F, Souza de Araújo FH, Honaiser Lescano C, Cardoso CAL, Oesterreich SA, Vieira MDC.

Drug Chem Toxicol. 2018 Jul 25:1-8. doi: 10.1080/01480545.2018.1488862. [Epub ahead of print]

PMID:
30044655
19.

Correlates of metabolic syndrome among young Brazilian adolescents population.

Dos Santos MC, de Castro Coutinho APC, de Souza Dantas M, Yabunaka LAM, Guedes DP, Oesterreich SA.

Nutr J. 2018 Jul 6;17(1):66. doi: 10.1186/s12937-018-0371-9.

20.

Preclinical safety evaluation of the ethanolic extract from Campomanesia pubescens (Mart. ex DC.) O.BERG (guavira) fruits: analysis of genotoxicity and clastogenic effects.

Villas Boas GR, Souza de Araújo FH, Moreira Marcelino J, Almeida Castro LH, Stefanello da Silveira AP, Silva Nacer R, Rodrigues de Souza F, Cardoso CAL, Boerngen de Lacerda R, Guterres ZDR, Oesterreich SA.

Food Funct. 2018 Jul 17;9(7):3707-3717. doi: 10.1039/c8fo01017j.

PMID:
29978171
21.

Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets.

Varešlija D, Priedigkeit N, Fagan A, Purcell S, Cosgrove N, O'Halloran PJ, Ward E, Cocchiglia S, Hartmaier R, Castro CA, Zhu L, Tseng GC, Lucas PC, Puhalla SL, Brufsky AM, Hamilton RL, Mathew A, Leone JP, Basudan A, Hudson L, Dwyer R, Das S, O'Connor DP, Buckley PG, Farrell M, Hill ADK, Oesterreich S, Lee AV, Young LS.

J Natl Cancer Inst. 2019 Apr 1;111(4):388-398. doi: 10.1093/jnci/djy110.

22.

Loss of E-cadherin Enhances IGF1-IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors.

Nagle AM, Levine KM, Tasdemir N, Scott JA, Burlbaugh K, Kehm J, Katz TA, Boone DN, Jacobsen BM, Atkinson JM, Oesterreich S, Lee AV.

Clin Cancer Res. 2018 Oct 15;24(20):5165-5177. doi: 10.1158/1078-0432.CCR-18-0279. Epub 2018 Jun 25.

23.

Heterogeneity in Metastatic Breast Cancer 18F-Fluoroestradiol Uptake: Clinically Actionable, Biologically Illuminating?

Kurland BF, Oesterreich S.

J Nucl Med. 2018 Aug;59(8):1210-1211. doi: 10.2967/jnumed.118.214304. Epub 2018 Jun 14. No abstract available.

24.

Precision Medicine in Hormone Receptor-Positive Breast Cancer.

Nasrazadani A, Thomas RA, Oesterreich S, Lee AV.

Front Oncol. 2018 May 4;8:144. doi: 10.3389/fonc.2018.00144. eCollection 2018. Review.

25.

Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism.

Du T, Zhu L, Levine KM, Tasdemir N, Lee AV, Vignali DAA, Houten BV, Tseng GC, Oesterreich S.

Sci Rep. 2018 May 8;8(1):7205. doi: 10.1038/s41598-018-25357-0.

26.

Preclinical safety evaluation of the ethanolic extract from guavira fruits (Campomanesia pubescens (D.C.) O. BERG) in experimental models of acute and short-term toxicity in rats.

Villas Boas GR, Carvalho Dos Santos A, Carvalho Souza RI, Souza de Araújo FH, Traesel GK, Marcelino JM, Stefanello da Silveira AP, Feitosa Farinelli BC, Lima Cardoso CA, Boerngen de Lacerda R, Oesterreich SA.

Food Chem Toxicol. 2018 Aug;118:1-12. doi: 10.1016/j.fct.2018.04.063. Epub 2018 Apr 30.

PMID:
29723584
27.

The ethanolic extract obtained from Campomanesia pubescens (D.C.) O.BERG fruits exerts anxiolytic and antidepressant effects on chronic mild stress model and on anxiety models in Wistar rats: Behavioral evidences.

Villas Boas GR, Stefanello da Silveira AP, Feitosa Farinelli BC, Lima Cardoso CA, Arce E, Oesterreich SA.

Nutr Neurosci. 2018 May 1:1-11. doi: 10.1080/1028415X.2018.1466513. [Epub ahead of print]

PMID:
29712539
28.

HDAC5-LSD1 axis regulates antineoplastic effect of natural HDAC inhibitor sulforaphane in human breast cancer cells.

Cao C, Wu H, Vasilatos SN, Chandran U, Qin Y, Wan Y, Oesterreich S, Davidson NE, Huang Y.

Int J Cancer. 2018 Sep 15;143(6):1388-1401. doi: 10.1002/ijc.31419. Epub 2018 Apr 20.

29.

Etiology of Acute Coronary Syndrome after Noncardiac Surgery.

Helwani MA, Amin A, Lavigne P, Rao S, Oesterreich S, Samaha E, Brown JC, Nagele P.

Anesthesiology. 2018 Jun;128(6):1084-1091. doi: 10.1097/ALN.0000000000002107.

30.

Opening the Door for Immune Oncology Studies in Invasive Lobular Breast Cancer.

Oesterreich S, Lucas PC, McAuliffe PF, Bruno TC, Vignali DAA.

J Natl Cancer Inst. 2018 Jul 1;110(7):696-698. doi: 10.1093/jnci/djy014. No abstract available.

PMID:
29471462
31.

Recurrent hyperactive ESR1 fusion proteins in endocrine therapy-resistant breast cancer.

Hartmaier RJ, Trabucco SE, Priedigkeit N, Chung JH, Parachoniak CA, Vanden Borre P, Morley S, Rosenzweig M, Gay LM, Goldberg ME, Suh J, Ali SM, Ross J, Leyland-Jones B, Young B, Williams C, Park B, Tsai M, Haley B, Peguero J, Callahan RD, Sachelarie I, Cho J, Atkinson JM, Bahreini A, Nagle AM, Puhalla SL, Watters RJ, Erdogan-Yildirim Z, Cao L, Oesterreich S, Mathew A, Lucas PC, Davidson NE, Brufsky AM, Frampton GM, Stephens PJ, Chmielecki J, Lee AV.

Ann Oncol. 2018 Apr 1;29(4):872-880. doi: 10.1093/annonc/mdy025.

32.

Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes.

Jia S, Miedel MT, Ngo M, Hessenius R, Chen N, Wang P, Bahreini A, Li Z, Ding Z, Shun TY, Zuckerman DM, Taylor DL, Puhalla SL, Lee AV, Oesterreich S, Stern AM.

Oncology. 2018;94(3):176-189. doi: 10.1159/000485510. Epub 2018 Jan 6.

33.

The CARMA3-Bcl10-MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor-Positive Breast Cancer.

Ekambaram P, Lee JL, Hubel NE, Hu D, Yerneni S, Campbell PG, Pollock N, Klei LR, Concel VJ, Delekta PC, Chinnaiyan AM, Tomlins SA, Rhodes DR, Priedigkeit N, Lee AV, Oesterreich S, McAllister-Lucas LM, Lucas PC.

Cancer Res. 2018 Mar 1;78(5):1225-1240. doi: 10.1158/0008-5472.CAN-17-1089. Epub 2017 Dec 19.

34.

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance.

Martin LA, Ribas R, Simigdala N, Schuster E, Pancholi S, Tenev T, Gellert P, Buluwela L, Harrod A, Thornhill A, Nikitorowicz-Buniak J, Bhamra A, Turgeon MO, Poulogiannis G, Gao Q, Martins V, Hills M, Garcia-Murillas I, Fribbens C, Patani N, Li Z, Sikora MJ, Turner N, Zwart W, Oesterreich S, Carroll J, Ali S, Dowsett M.

Nat Commun. 2017 Nov 30;8(1):1865. doi: 10.1038/s41467-017-01864-y.

35.

Functional characterization of lysine-specific demethylase 2 (LSD2/KDM1B) in breast cancer progression.

Chen L, Vasilatos SN, Qin Y, Katz TA, Cao C, Wu H, Tasdemir N, Levine KM, Oesterreich S, Davidson NE, Huang Y.

Oncotarget. 2017 Jul 19;8(47):81737-81753. doi: 10.18632/oncotarget.19387. eCollection 2017 Oct 10.

36.

Determinants of prolactin in postmenopausal Chinese women in Singapore.

Katz TA, Wu AH, Stanczyk FZ, Wang R, Koh WP, Yuan JM, Oesterreich S, Butler LM.

Cancer Causes Control. 2018 Jan;29(1):51-62. doi: 10.1007/s10552-017-0978-8. Epub 2017 Nov 9.

37.

Evaluation of embryotoxic and teratogenic effects of the oil extracted from Caryocar brasiliense Cambess pulp in rats.

Traesel GK, de Lima FF, Dos Santos AC, Souza RIC, Cantadori DT, Kretschmer CR, Navarini VJ, Oesterreich SA.

Food Chem Toxicol. 2017 Dec;110:74-82. doi: 10.1016/j.fct.2017.10.018. Epub 2017 Oct 12.

PMID:
29032167
38.

Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer Cells.

Li Z, Levine KM, Bahreini A, Wang P, Chu D, Park BH, Oesterreich S, Lee AV.

Endocrinology. 2018 Jan 1;159(1):285-296. doi: 10.1210/en.2017-00693.

39.

Estradiol as a Targeted, Late-Line Therapy in Metastatic Breast Cancer with Estrogen Receptor Amplification.

Kota K, Brufsky A, Oesterreich S, Lee A.

Cureus. 2017 Jul 6;9(7):e1434. doi: 10.7759/cureus.1434.

40.

Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors.

Zhao Y, Laws MJ, Guillen VS, Ziegler Y, Min J, Sharma A, Kim SH, Chu D, Park BH, Oesterreich S, Mao C, Shapiro DJ, Nettles KW, Katzenellenbogen JA, Katzenellenbogen BS.

Cancer Res. 2017 Oct 15;77(20):5602-5613. doi: 10.1158/0008-5472.CAN-17-1265. Epub 2017 Sep 13.

41.

Exome-capture RNA sequencing of decade-old breast cancers and matched decalcified bone metastases.

Priedigkeit N, Watters RJ, Lucas PC, Basudan A, Bhargava R, Horne W, Kolls JK, Fang Z, Rosenzweig MQ, Brufsky AM, Weiss KR, Oesterreich S, Lee AV.

JCI Insight. 2017 Sep 7;2(17). pii: 95703. doi: 10.1172/jci.insight.95703. eCollection 2017 Sep 7.

42.

Distinct Pattern of Metastases in Patients with Invasive Lobular Carcinoma of the Breast.

Mathew A, Rajagopal PS, Villgran V, Sandhu GS, Jankowitz RC, Jacob M, Rosenzweig M, Oesterreich S, Brufsky A.

Geburtshilfe Frauenheilkd. 2017 Jun;77(6):660-666. doi: 10.1055/s-0043-109374. Epub 2017 Jun 28.

43.

CYP2D6 genotype is not associated with survival in breast cancer patients treated with tamoxifen: results from a population-based study.

Hertz DL, Kidwell KM, Hilsenbeck SG, Oesterreich S, Osborne CK, Philips S, Chenault C, Hartmaier RJ, Skaar TC, Sikora MJ, Rae JM.

Breast Cancer Res Treat. 2017 Nov;166(1):277-287. doi: 10.1007/s10549-017-4400-8. Epub 2017 Jul 20.

44.

Safety Assessment of Oil from Pequi (Caryocar brasiliense Camb.): Evaluation of the Potential Genotoxic and Clastogenic Effects.

Traesel GK, de Araújo FHS, Castro LHA, de Lima FF, Menegati SELT, Justi PN, Kassuya CAL, Cardoso CAL, Argandoña EJS, Oesterreich SA.

J Med Food. 2017 Aug;20(8):804-811. doi: 10.1089/jmf.2017.0021. Epub 2017 May 30.

PMID:
28557544
45.

A Joint Bayesian Model for Integrating Microarray and RNA Sequencing Transcriptomic Data.

Ma T, Liang F, Oesterreich S, Tseng GC.

J Comput Biol. 2017 Jul;24(7):647-662. doi: 10.1089/cmb.2017.0056. Epub 2017 May 25.

46.

Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models.

Bahreini A, Li Z, Wang P, Levine KM, Tasdemir N, Cao L, Weir HM, Puhalla SL, Davidson NE, Stern AM, Chu D, Park BH, Lee AV, Oesterreich S.

Breast Cancer Res. 2017 May 23;19(1):60. doi: 10.1186/s13058-017-0851-4.

47.

A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7.

Hopkins BL, Nadler M, Skoko JJ, Bertomeu T, Pelosi A, Shafaei PM, Levine K, Schempf A, Pennarun B, Yang B, Datta D, Bucur O, Ndebele K, Oesterreich S, Yang D, Giulia Rizzo M, Khosravi-Far R, Neumann CA.

Antioxid Redox Signal. 2018 Jan 1;28(1):62-77. doi: 10.1089/ars.2016.6871. Epub 2017 May 1.

48.

Safety Assessment and Botanical Standardization of an Edible Species from South America.

Traesel GK, Machado CD, Tirloni CAS, Menetrier JV, Dos Reis Lívero FA, Lourenço ELB, Oesterreich SA, Budel JM, Junior AG.

J Med Food. 2017 May;20(5):519-525. doi: 10.1089/jmf.2016.0143. Epub 2017 Apr 4.

PMID:
28375765
49.

Acute and subacute oral toxicity assessment of the oil extracted from Attalea phalerata Mart ex Spreng. pulp fruit in rats.

Freitas de Lima F, Traesel GK, Menegati SE, Santos AC, Souza RI, de Oliveira VS, Sanjinez-Argandoña EJ, Cardoso CA, Oesterreich SA, Vieira MD.

Food Res Int. 2017 Jan;91:11-17. doi: 10.1016/j.foodres.2016.11.019. Epub 2016 Nov 19.

PMID:
28290314
50.

Steroid receptor coactivator-1 can regulate osteoblastogenesis independently of estrogen.

Watters RJ, Hartmaier RJ, Osmanbeyoglu HU, Gillihan RM, Rae JM, Liao L, Chen K, Li W, Lu X, Oesterreich S.

Mol Cell Endocrinol. 2017 Jun 15;448:21-27. doi: 10.1016/j.mce.2017.03.005. Epub 2017 Mar 7.

PMID:
28286232

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