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Items: 1 to 50 of 532

1.

Open letter to the German Research Foundation (DFG, Deutsche Forschungsgemeinschaft). Some comments on the recent exclusion of a renowned scientist from a toxicological commission.

Oesch F.

Toxicol Lett. 2019 May 15;306:11-12. doi: 10.1016/j.toxlet.2019.02.004. Epub 2019 Feb 8. No abstract available.

PMID:
30742881
2.

Correction to: Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models.

Oesch F, Fabian E, Landsiedel R.

Arch Toxicol. 2018 Nov;92(11):3439. doi: 10.1007/s00204-018-2301-1.

3.

Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models.

Oesch F, Fabian E, Landsiedel R.

Arch Toxicol. 2018 Aug;92(8):2411-2456. doi: 10.1007/s00204-018-2232-x. Epub 2018 Jun 18. Review. Erratum in: Arch Toxicol. 2018 Nov;92(11):3439.

4.

Adverse outcome pathways: opportunities, limitations and open questions.

Leist M, Ghallab A, Graepel R, Marchan R, Hassan R, Bennekou SH, Limonciel A, Vinken M, Schildknecht S, Waldmann T, Danen E, van Ravenzwaay B, Kamp H, Gardner I, Godoy P, Bois FY, Braeuning A, Reif R, Oesch F, Drasdo D, Höhme S, Schwarz M, Hartung T, Braunbeck T, Beltman J, Vrieling H, Sanz F, Forsby A, Gadaleta D, Fisher C, Kelm J, Fluri D, Ecker G, Zdrazil B, Terron A, Jennings P, van der Burg B, Dooley S, Meijer AH, Willighagen E, Martens M, Evelo C, Mombelli E, Taboureau O, Mantovani A, Hardy B, Koch B, Escher S, van Thriel C, Cadenas C, Kroese D, van de Water B, Hengstler JG.

Arch Toxicol. 2017 Nov;91(11):3477-3505. doi: 10.1007/s00204-017-2045-3. Epub 2017 Oct 19. Review.

PMID:
29051992
5.

A protocol to determine dermal absorption of xenobiotica through human skin in vitro.

Fabian E, Oesch F, Ott K, Landsiedel R, van Ravenzwaay B.

Arch Toxicol. 2017 Mar;91(3):1497-1511. doi: 10.1007/s00204-016-1782-z. Epub 2016 Jul 5.

PMID:
27380014
6.

The nucleotide excision repair protein XPC is essential for bulky DNA adducts to promote interleukin-6 expression via the activation of p38-SAPK.

Schreck I, Grico N, Hansjosten I, Marquardt C, Bormann S, Seidel A, Kvietkova DL, Pieniazek D, Segerbäck D, Diabaté S, van der Horst GT, Oesch-Bartlomowicz B, Oesch F, Weiss C.

Oncogene. 2016 Feb 18;35(7):908-18. doi: 10.1038/onc.2015.145. Epub 2015 May 18.

PMID:
25982271
7.

Xenobiotic-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models.

Oesch F, Fabian E, Guth K, Landsiedel R.

Arch Toxicol. 2014 Dec;88(12):2135-90. doi: 10.1007/s00204-014-1382-8. Epub 2014 Nov 5. Review.

8.

Extrahepatic metabolism at the body's internal-external interfaces.

Gundert-Remy U, Bernauer U, Blömeke B, Döring B, Fabian E, Goebel C, Hessel S, Jäckh C, Lampen A, Oesch F, Petzinger E, Völkel W, Roos PH.

Drug Metab Rev. 2014 Aug;46(3):291-324. doi: 10.3109/03602532.2014.900565. Epub 2014 Mar 25. Review.

PMID:
24666398
9.

Xenobiotic metabolizing enzyme activities in cells used for testing skin sensitization in vitro.

Fabian E, Vogel D, Blatz V, Ramirez T, Kolle S, Eltze T, van Ravenzwaay B, Oesch F, Landsiedel R.

Arch Toxicol. 2013 Sep;87(9):1683-96.

PMID:
23958860
10.

Toxico-/biokinetics of nanomaterials.

Landsiedel R, Fabian E, Ma-Hock L, van Ravenzwaay B, Wohlleben W, Wiench K, Oesch F.

Arch Toxicol. 2012 Jul;86(7):1021-60. doi: 10.1007/s00204-012-0858-7. Epub 2012 May 11. Review. Erratum in: Arch Toxicol. 2012 Jul;86(7):1061.

PMID:
22576463
11.

Genotoxicity investigations on nanomaterials.

Oesch F, Landsiedel R.

Arch Toxicol. 2012 Jul;86(7):985-94. doi: 10.1007/s00204-012-0838-y. Epub 2012 Mar 29. Review.

PMID:
22456836
12.

Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblasts.

Faust D, Schmitt C, Oesch F, Oesch-Bartlomowicz B, Schreck I, Weiss C, Dietrich C.

Cell Commun Signal. 2012 Mar 9;10:6. doi: 10.1186/1478-811X-10-6.

13.

Synthesis, absolute configuration, and bacterial mutagenicity of the 8 stereoisomeric vicinal diol epoxides at the terminal benzo ring of carcinogenic dibenz[a,h]anthracene.

Frank H, Funk M, Oesch F, Platt KL.

Chem Res Toxicol. 2011 Dec 19;24(12):2258-68. doi: 10.1021/tx200398b. Epub 2011 Nov 16.

PMID:
22087540
14.

Gene toxicity studies on titanium dioxide and zinc oxide nanomaterials used for UV-protection in cosmetic formulations.

Landsiedel R, Ma-Hock L, Van Ravenzwaay B, Schulz M, Wiench K, Champ S, Schulte S, Wohlleben W, Oesch F.

Nanotoxicology. 2010 Dec;4:364-81. doi: 10.3109/17435390.2010.506694.

PMID:
20925445
15.

In vitro mammalian metabolism of the mitosis inhibitor zoxamide and the relationship to its in vitro toxicity.

Oesch F, Metzler M, Fabian E, Kamp H, Bernshausen T, Damm G, Triebel S, Döhmer J, Landsiedel R, Van Ravenzwaay B.

Xenobiotica. 2010 Jan;40(1):72-82. doi: 10.3109/00498250903353464.

PMID:
20001673
16.

Stem cells in chemical carcinogenesis.

Dietrich C, Weiss C, Bockamp E, Brisken C, Roskams T, Morris R, Oesch-Bartlomowicz B, Oesch F.

Arch Toxicol. 2010 Mar;84(3):245-51. doi: 10.1007/s00204-009-0491-2. Epub 2009 Nov 26. No abstract available.

PMID:
19941131
17.

Editorial.

Oesch F, Oesch-Bartlomowicz B.

Mutat Res. 2009 Nov-Dec;680(1-2):82. doi: 10.1016/j.mrgentox.2009.10.007. Epub 2009 Oct 15. No abstract available.

PMID:
19836464
18.

Circadian rhythms and chemical carcinogenesis: Potential link. An overview.

Oesch-Bartlomowicz B, Weiss C, Dietrich C, Oesch F.

Mutat Res. 2009 Nov-Dec;680(1-2):83-6. doi: 10.1016/j.mrgentox.2009.10.006. Epub 2009 Oct 15.

PMID:
19836463
19.

General conclusions.

Watelet JB, Benedetti MS, Church MK, Oesch F.

Drug Metab Rev. 2009;41(3):528-9. doi: 10.1080/10837450902891097. No abstract available.

PMID:
19601725
20.

Importance of knowledge on drug metabolism for the safe use of drugs in humans.

Oesch F.

Drug Metab Rev. 2009;41(3):298-300. doi: 10.1080/10837450902890958. No abstract available.

PMID:
19601716
21.

Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells.

Schreck I, Chudziak D, Schneider S, Seidel A, Platt KL, Oesch F, Weiss C.

Toxicology. 2009 May 17;259(3):91-6. doi: 10.1016/j.tox.2009.02.006. Epub 2009 Feb 28.

PMID:
19428948
22.

Effects of an acute exposure to toluene on the DNA repair activity of the human 8-oxoguanine DNA glycosylase 1 (hOGG1) in healthy subjects.

Finkenwirth P, Spelmeyer U, Hommel G, Rose DM, Jung D, Rossbach B, Mayer-Popken O, Platt KL, Oesch F, Muttray A.

Arch Toxicol. 2009 Aug;83(8):777-84. doi: 10.1007/s00204-009-0415-1. Epub 2009 Mar 25.

PMID:
19319507
23.

Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers.

Landsiedel R, Kapp MD, Schulz M, Wiench K, Oesch F.

Mutat Res. 2009 Mar-Jun;681(2-3):241-58. doi: 10.1016/j.mrrev.2008.10.002. Epub 2008 Nov 11. Review.

PMID:
19041420
24.

Role of cAMP in mediating AHR signaling.

Oesch-Bartlomowicz B, Oesch F.

Biochem Pharmacol. 2009 Feb 15;77(4):627-41. doi: 10.1016/j.bcp.2008.10.017. Epub 2008 Nov 1. Review.

PMID:
19013136
25.

New aspects on mechanisms of chemical carcinogenesis: emphasis on species and gender/sex differences and developmental/aging determinants.

Oesch F, Dietrich C, Naegeli H, Schwarz M, van der Horst G, Zanger U, Oesch B, Weiss C.

Arch Toxicol. 2008 Nov;82(11):875-80. doi: 10.1007/s00204-008-0368-9. Epub 2008 Oct 15. No abstract available.

PMID:
18854980
26.

Phosphorylation of xenobiotic-metabolizing cytochromes P450.

Oesch-Bartlomowicz B, Oesch F.

Anal Bioanal Chem. 2008 Nov;392(6):1085-92. doi: 10.1007/s00216-008-2315-2. Epub 2008 Aug 14. Review.

PMID:
18704375
27.

Drug-metabolizing enzymes in the skin of man, rat, and pig.

Oesch F, Fabian E, Oesch-Bartlomowicz B, Werner C, Landsiedel R.

Drug Metab Rev. 2007;39(4):659-98. Review.

PMID:
18058329
28.

TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A.

Weiss C, Faust D, Schreck I, Ruff A, Farwerck T, Melenberg A, Schneider S, Oesch-Bartlomowicz B, Zatloukalová J, Vondrácek J, Oesch F, Dietrich C.

Oncogene. 2008 Apr 3;27(15):2198-207. Epub 2007 Oct 22.

PMID:
17952121
29.
30.

CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA).

Carmo H, Brulport M, Hermes M, Oesch F, de Boer D, Remião F, Carvalho F, Schön MR, Krebsfaenger N, Doehmer J, Bastos Mde L, Hengstler JG.

Toxicology. 2007 Jan 18;229(3):236-44. Epub 2006 Dec 5.

PMID:
17156908
31.

Styrene metabolism, genotoxicity, and potential carcinogenicity.

Vodicka P, Koskinen M, Naccarati A, Oesch-Bartlomowicz B, Vodickova L, Hemminki K, Oesch F.

Drug Metab Rev. 2006;38(4):805-53. Review.

PMID:
17145703
32.

Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity.

Carmo H, Brulport M, Hermes M, Oesch F, Silva R, Ferreira LM, Branco PS, Boer Dd, Remião F, Carvalho F, Schön MR, Krebsfaenger N, Doehmer J, Bastos Mde L, Hengstler JG.

Pharmacogenet Genomics. 2006 Nov;16(11):789-99.

PMID:
17047487
33.

Generation of human hepatocytes by stem cell technology: definition of the hepatocyte.

Hengstler JG, Brulport M, Schormann W, Bauer A, Hermes M, Nussler AK, Fandrich F, Ruhnke M, Ungefroren H, Griffin L, Bockamp E, Oesch F, von Mach MA.

Expert Opin Drug Metab Toxicol. 2005 Jun;1(1):61-74. Review.

PMID:
16922653
34.

Analysis of reproductive toxicity and classification of glufosinate-ammonium.

Schulte-Hermann R, Wogan GN, Berry C, Brown NA, Czeizel A, Giavini E, Holmes LB, Kroes R, Nau H, Neubert D, Oesch F, Ott T, Pelkonen O, Robert-Gnansia E, Sullivan FM.

Regul Toxicol Pharmacol. 2006 Apr;44(3 Suppl 1):S1-76. Epub 2006 Feb 28.

PMID:
16510221
35.

Dephosphorylation of p-ERK1/2 in relation to tumor remission after HER-2 and Raf1 blocking therapy in a conditional mouse tumor model.

Hausherr CK, Schiffer IB, Gebhard S, Banić A, Tanner B, Kolbl H, Thoenes E, Beckers T, Spangenberg C, Prawitt D, Trost T, Zabel B, Oesch F, Hermes M, Hengstler JG.

Mol Carcinog. 2006 May;45(5):302-8.

PMID:
16496387
36.

Epoxide hydrolases: structure, function, mechanism, and assay.

Arand M, Cronin A, Adamska M, Oesch F.

Methods Enzymol. 2005;400:569-88. Review.

PMID:
16399371
37.

Phosphorylation of cytochromes P450: first discovery of a posttranslational modification of a drug-metabolizing enzyme.

Oesch-Bartlomowicz B, Oesch F.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):446-9. Epub 2005 Aug 22. Review.

PMID:
16137648
38.

p38alpha MAPK is required for contact inhibition.

Faust D, Dolado I, Cuadrado A, Oesch F, Weiss C, Nebreda AR, Dietrich C.

Oncogene. 2005 Nov 24;24(53):7941-5.

PMID:
16027723
39.

Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways.

Oesch-Bartlomowicz B, Huelster A, Wiss O, Antoniou-Lipfert P, Dietrich C, Arand M, Weiss C, Bockamp E, Oesch F.

Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9218-23. Epub 2005 Jun 21.

40.

TCDD induces c-jun expression via a novel Ah (dioxin) receptor-mediated p38-MAPK-dependent pathway.

Weiss C, Faust D, Dürk H, Kolluri SK, Pelzer A, Schneider S, Dietrich C, Oesch F, Göttlicher M.

Oncogene. 2005 Jul 21;24(31):4975-83.

PMID:
15897893
41.

Acute exposure to 50ppm toluene does not increase sleepiness.

Muttray A, Spelmeyer U, Hommel G, Oesch F, Jung D, Rose DM, Mayer-Popken O, Rossbach B, Letzel S.

Environ Toxicol Pharmacol. 2005 May;19(3):665-9. doi: 10.1016/j.etap.2004.12.034.

PMID:
21783540
42.

Evaluation of the role of c-Src and ERK in TCDD-dependent release from contact-inhibition in WB-F344 cells.

Hoelper P, Faust D, Oesch F, Dietrich C.

Arch Toxicol. 2005 Apr;79(4):201-7. Epub 2004 Dec 11.

PMID:
15592923
43.

Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction.

Ringel M, von Mach MA, Santos R, Feilen PJ, Brulport M, Hermes M, Bauer AW, Schormann W, Tanner B, Schön MR, Oesch F, Hengstler JG.

Toxicology. 2005 Jan 5;206(1):153-67.

PMID:
15590115
44.

Metabolic pathways of 4-bromo-2,5-dimethoxyphenethylamine (2C-B): analysis of phase I metabolism with hepatocytes of six species including human.

Carmo H, Hengstler JG, de Boer D, Ringel M, Remião F, Carvalho F, Fernandes E, dos Reys LA, Oesch F, de Lourdes Bastos M.

Toxicology. 2005 Jan 5;206(1):75-89.

PMID:
15590110
45.

Transforming growth factor-beta1 is not involved in TCDD-dependent release from contact inhibition in WB-F344 cells.

Hoelper P, Faust D, Oesch F, Dietrich C.

Arch Toxicol. 2005 Jan;79(1):31-6. Epub 2004 Sep 21.

PMID:
15448980
46.

Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron.

Efferth T, Benakis A, Romero MR, Tomicic M, Rauh R, Steinbach D, Häfer R, Stamminger T, Oesch F, Kaina B, Marschall M.

Free Radic Biol Med. 2004 Oct 1;37(7):998-1009.

PMID:
15336316
47.
48.

RNAi knock-down mice: an emerging technology for post-genomic functional genetics.

Prawitt D, Brixel L, Spangenberg C, Eshkind L, Heck R, Oesch F, Zabel B, Bockamp E.

Cytogenet Genome Res. 2004;105(2-4):412-21. Review.

PMID:
15237229
49.
50.

Metabolism of propafenone and verapamil by cryopreserved human, rat, mouse and dog hepatocytes: comparison with metabolism in vivo.

Reder-Hilz B, Ullrich M, Ringel M, Hewitt N, Utesch D, Oesch F, Hengstler JG.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Apr;369(4):408-17. Epub 2004 Mar 4.

PMID:
14999438

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