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Items: 13


Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51.

Kaplan AR, Gueble SE, Liu Y, Oeck S, Kim H, Yun Z, Glazer PM.

Sci Transl Med. 2019 May 15;11(492). pii: eaav4508. doi: 10.1126/scitranslmed.aav4508.


High-throughput Evaluation of Protein Migration and Localization after Laser Micro-Irradiation.

Oeck S, Malewicz NM, Krysztofiak A, Turchick A, Jendrossek V, Glazer PM.

Sci Rep. 2019 Feb 28;9(1):3148. doi: 10.1038/s41598-019-39760-8.


Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons.

Oeck S, Szymonowicz K, Wiel G, Krysztofiak A, Lambert J, Koska B, Iliakis G, Timmermann B, Jendrossek V.

Int J Mol Sci. 2018 Nov 28;19(12). pii: E3779. doi: 10.3390/ijms19123779.


Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells.

Szymonowicz K, Oeck S, Krysztofiak A, van der Linden J, Iliakis G, Jendrossek V.

Int J Mol Sci. 2018 Jul 31;19(8). pii: E2233. doi: 10.3390/ijms19082233.


Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair.

Sulkowski PL, Sundaram RK, Oeck S, Corso CD, Liu Y, Noorbakhsh S, Niger M, Boeke M, Ueno D, Kalathil AN, Bao X, Li J, Shuch B, Bindra RS, Glazer PM.

Nat Genet. 2018 Aug;50(8):1086-1092. doi: 10.1038/s41588-018-0170-4. Epub 2018 Jul 16.


Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1.

Lu Y, Liu Y, Oeck S, Glazer PM.

Mol Cancer Res. 2018 Oct;16(10):1458-1469. doi: 10.1158/1541-7786.MCR-17-0637. Epub 2018 Jun 22.


PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF.

Sulkowski PL, Scanlon SE, Oeck S, Glazer PM.

Mol Cancer Res. 2018 Aug;16(8):1241-1254. doi: 10.1158/1541-7786.MCR-17-0581. Epub 2018 May 8.


New Insights into Protein Kinase B/Akt Signaling: Role of Localized Akt Activation and Compartment-Specific Target Proteins for the Cellular Radiation Response.

Szymonowicz K, Oeck S, Malewicz NM, Jendrossek V.

Cancers (Basel). 2018 Mar 18;10(3). pii: E78. doi: 10.3390/cancers10030078. Review.


Epigenetic Mechanisms of ATM Activation after Helicobacter pylori Infection.

Santos JC, Gambeloni RZ, Roque AT, Oeck S, Ribeiro ML.

Am J Pathol. 2018 Feb;188(2):329-335. doi: 10.1016/j.ajpath.2017.10.005. Epub 2017 Nov 9.


The Focinator v2-0 - Graphical Interface, Four Channels, Colocalization Analysis and Cell Phase Identification.

Oeck S, Malewicz NM, Hurst S, Al-Refae K, Krysztofiak A, Jendrossek V.

Radiat Res. 2017 Jul;188(1):114-120. doi: 10.1667/RR14746.1. Epub 2017 May 11.


Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity.

Oeck S, Al-Refae K, Riffkin H, Wiel G, Handrick R, Klein D, Iliakis G, Jendrossek V.

Sci Rep. 2017 Feb 17;7:42700. doi: 10.1038/srep42700.


The Focinator - a new open-source tool for high-throughput foci evaluation of DNA damage.

Oeck S, Malewicz NM, Hurst S, Rudner J, Jendrossek V.

Radiat Oncol. 2015 Aug 4;10:163. doi: 10.1186/s13014-015-0453-1.


Covalent-Allosteric Kinase Inhibitors.

Weisner J, Gontla R, van der Westhuizen L, Oeck S, Ketzer J, Janning P, Richters A, M├╝hlenberg T, Fang Z, Taher A, Jendrossek V, Pelly SC, Bauer S, van Otterlo WA, Rauh D.

Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10313-6. doi: 10.1002/anie.201502142. Epub 2015 Jun 25.


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