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Items: 26


Inositol phosphate multikinase dependent transcriptional control.

Hatch AJ, Odom AR, York JD.

Adv Biol Regul. 2017 May;64:9-19. doi: 10.1016/j.jbior.2017.03.001. Epub 2017 Mar 21.


A Novel Fluorescence Resonance Energy Transfer-Based Screen in High-Throughput Format To Identify Inhibitors of Malarial and Human Glucose Transporters.

Kraft TE, Heitmeier MR, Putanko M, Edwards RL, Ilagan MX, Payne MA, Autry JM, Thomas DD, Odom AR, Hruz PW.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7407-7414. Print 2016 Dec.


Structure-Activity Relationships of the MEPicides: N-Acyl and O-Linked Analogs of FR900098 as Inhibitors of Dxr from Mycobacterium tuberculosis and Yersinia pestis.

San Jose G, Jackson ER, Haymond A, Johny C, Edwards RL, Wang X, Brothers RC, Edelstein EK, Odom AR, Boshoff HI, Couch RD, Dowd CS.

ACS Infect Dis. 2016 Dec 9;2(12):923-935. Epub 2016 Oct 12.


Whole-Genome Sequencing to Evaluate the Resistance Landscape Following Antimalarial Treatment Failure With Fosmidomycin-Clindamycin.

Guggisberg AM, Sundararaman SA, Lanaspa M, Moraleda C, González R, Mayor A, Cisteró P, Hutchinson D, Kremsner PG, Hahn BH, Bassat Q, Odom AR.

J Infect Dis. 2016 Oct 1;214(7):1085-91. doi: 10.1093/infdis/jiw304. Epub 2016 Jul 20.


Plasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target.

Imlay LS, Armstrong CM, Masters MC, Li T, Price KE, Edwards RL, Mann KM, Li LX, Stallings CL, Berry NG, O'Neill PM, Odom AR.

ACS Infect Dis. 2015 Apr 10;1(4):157-167. Epub 2015 Mar 2.


Determinants of Anemia and Hemoglobin Concentration in Haitian School-Aged Children.

Iannotti LL, Delnatus JR, Odom AR, Eaton JC, Griggs JJ, Brown S, Wolff PB.

Am J Trop Med Hyg. 2015 Nov;93(5):1092-8. doi: 10.4269/ajtmh.15-0073. Epub 2015 Sep 8.


Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.

Park J, Guggisberg AM, Odom AR, Tolia NH.

Acta Crystallogr D Biol Crystallogr. 2015 Sep;71(Pt 9):1824-34. doi: 10.1107/S1399004715012067. Epub 2015 Aug 25.


Sweet Talk: Regulating Glucose Metabolism in Toxoplasma.

Guggisberg AM, Odom AR.

Cell Host Microbe. 2015 Aug 12;18(2):142-3. doi: 10.1016/j.chom.2015.07.012.


The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir.

Kraft TE, Armstrong C, Heitmeier MR, Odom AR, Hruz PW.

Antimicrob Agents Chemother. 2015 Oct;59(10):6203-9. doi: 10.1128/AAC.00899-15. Epub 2015 Jul 27.


Resistance to the antimicrobial agent fosmidomycin and an FR900098 prodrug through mutations in the deoxyxylulose phosphate reductoisomerase gene (dxr).

Armstrong CM, Meyers DJ, Imlay LS, Freel Meyers C, Odom AR.

Antimicrob Agents Chemother. 2015 Sep;59(9):5511-9. doi: 10.1128/AAC.00602-15. Epub 2015 Jun 29.


Isoprenoid metabolism in apicomplexan parasites.

Imlay L, Odom AR.

Curr Clin Microbiol Rep. 2014 Dec 1;1(3-4):37-50.


Malaria parasites produce volatile mosquito attractants.

Kelly M, Su CY, Schaber C, Crowley JR, Hsu FF, Carlson JR, Odom AR.

MBio. 2015 Mar 24;6(2). pii: e00235-15. doi: 10.1128/mBio.00235-15.


Isoprenoid biosynthesis in Plasmodium falciparum.

Guggisberg AM, Amthor RE, Odom AR.

Eukaryot Cell. 2014 Nov;13(11):1348-59. doi: 10.1128/EC.00160-14. Epub 2014 Sep 12. Review.


A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites.

Guggisberg AM, Park J, Edwards RL, Kelly ML, Hodge DM, Tolia NH, Odom AR.

Nat Commun. 2014 Jul 24;5:4467. doi: 10.1038/ncomms5467.


The triphenylethylenes, a novel class of antifungals.

Odom AR.

MBio. 2014 Apr 29;5(3):e01126-14. doi: 10.1128/mBio.01126-14.


Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum.

Howe R, Kelly M, Jimah J, Hodge D, Odom AR.

Eukaryot Cell. 2013 Feb;12(2):215-23. doi: 10.1128/EC.00073-12. Epub 2012 Dec 7.


Structural studies and protein engineering of inositol phosphate multikinase.

Endo-Streeter S, Tsui MK, Odom AR, Block J, York JD.

J Biol Chem. 2012 Oct 12;287(42):35360-9. doi: 10.1074/jbc.M112.365031. Epub 2012 Aug 15.


Five questions about non-mevalonate isoprenoid biosynthesis.

Odom AR.

PLoS Pathog. 2011 Dec;7(12):e1002323. doi: 10.1371/journal.ppat.1002323. Epub 2011 Dec 22. Review. No abstract available.


A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling.

Zhang B, Watts KM, Hodge D, Kemp LM, Hunstad DA, Hicks LM, Odom AR.

Biochemistry. 2011 May 3;50(17):3570-7. doi: 10.1021/bi200113y. Epub 2011 Apr 11.


Functional genetic analysis of the Plasmodium falciparum deoxyxylulose 5-phosphate reductoisomerase gene.

Odom AR, Van Voorhis WC.

Mol Biochem Parasitol. 2010 Apr;170(2):108-11. doi: 10.1016/j.molbiopara.2009.12.001. Epub 2009 Dec 16.


Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases.

Stevenson-Paulik J, Odom AR, York JD.

J Biol Chem. 2002 Nov 8;277(45):42711-8. Epub 2002 Sep 10.


An expanded view of inositol signaling.

York JD, Guo S, Odom AR, Spiegelberg BD, Stolz LE.

Adv Enzyme Regul. 2001;41:57-71. Review. No abstract available.


Characterization of the MFalpha pheromone of the human fungal pathogen cryptococcus neoformans.

Davidson RC, Moore TD, Odom AR, Heitman J.

Mol Microbiol. 2000 Dec;38(5):1017-26.


A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control.

Odom AR, Stahlberg A, Wente SR, York JD.

Science. 2000 Mar 17;287(5460):2026-9.


A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export.

York JD, Odom AR, Murphy R, Ives EB, Wente SR.

Science. 1999 Jul 2;285(5424):96-100.

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