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Items: 31


Tolerogenic Dendritic Cells Attenuate Experimental Autoimmune Antimyeloperoxidase Glomerulonephritis.

Odobasic D, Oudin V, Ito K, Gan PY, Kitching AR, Holdsworth SR.

J Am Soc Nephrol. 2019 Nov;30(11):2140-2157. doi: 10.1681/ASN.2019030236. Epub 2019 Aug 23.


OX40 ligand is inhibitory during the effector phase of crescentic glomerulonephritis.

Odobasic D, Ruth AJ, Oudin V, Kitching AR, Holdsworth SR.

Nephrol Dial Transplant. 2019 Mar 1;34(3):429-441. doi: 10.1093/ndt/gfy177.


Formyl peptide receptor activation inhibits the expansion of effector T cells and synovial fibroblasts and attenuates joint injury in models of rheumatoid arthritis.

Odobasic D, Jia Y, Kao W, Fan H, Wei X, Gu R, Ngo D, Kitching AR, Holdsworth SR, Morand EF, Yang YH.

Int Immunopharmacol. 2018 Aug;61:140-149. doi: 10.1016/j.intimp.2018.05.028. Epub 2018 Jun 4.


C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis.

Dick J, Gan PY, Ford SL, Odobasic D, Alikhan MA, Loosen SH, Hall P, Westhorpe CL, Li A, Ooi JD, Woodruff TM, Mackay CR, Kitching AR, Hickey MJ, Holdsworth SR.

Kidney Int. 2018 Mar;93(3):615-625. doi: 10.1016/j.kint.2017.09.018. Epub 2017 Dec 12.


Pathogenic Role for γδ T Cells in Autoimmune Anti-Myeloperoxidase Glomerulonephritis.

Gan PY, Fujita T, Ooi JD, Alikhan MA, Dick J, Shim R, Odobasic D, O'Sullivan KM, Kitching AR, Holdsworth SR.

J Immunol. 2017 Nov 1;199(9):3042-3050. doi: 10.4049/jimmunol.1602025. Epub 2017 Sep 27.


Neutrophil-Mediated Regulation of Innate and Adaptive Immunity: The Role of Myeloperoxidase.

Odobasic D, Kitching AR, Holdsworth SR.

J Immunol Res. 2016;2016:2349817. doi: 10.1155/2016/2349817. Epub 2016 Jan 20. Review.


Glucocorticoid-induced leucine zipper (GILZ) inhibits B cell activation in systemic lupus erythematosus.

Jones SA, Toh AE, Odobasic D, Oudin MA, Cheng Q, Lee JP, White SJ, Russ BE, Infantino S, Light A, Tarlinton DM, Harris J, Morand EF.

Ann Rheum Dis. 2016 Apr;75(4):739-47. doi: 10.1136/annrheumdis-2015-207744. Epub 2015 Nov 26.


Mast Cell Stabilization Ameliorates Autoimmune Anti-Myeloperoxidase Glomerulonephritis.

Gan PY, O'Sullivan KM, Ooi JD, Alikhan MA, Odobasic D, Summers SA, Kitching AR, Holdsworth SR.

J Am Soc Nephrol. 2016 May;27(5):1321-33. doi: 10.1681/ASN.2014090906. Epub 2015 Sep 15.


Endogenous Toll-Like Receptor 9 Regulates AKI by Promoting Regulatory T Cell Recruitment.

Alikhan MA, Summers SA, Gan PY, Chan AJ, Khouri MB, Ooi JD, Ghali JR, Odobasic D, Hickey MJ, Kitching AR, Holdsworth SR.

J Am Soc Nephrol. 2016 Mar;27(3):706-14. doi: 10.1681/ASN.2014090927. Epub 2015 Jun 26.


Suppression of Autoimmunity and Renal Disease in Pristane-Induced Lupus by Myeloperoxidase.

Odobasic D, Muljadi RC, O'Sullivan KM, Kettle AJ, Dickerhof N, Summers SA, Kitching AR, Holdsworth SR.

Arthritis Rheumatol. 2015 Jul;67(7):1868-80. doi: 10.1002/art.39109.


T cell mediated autoimmune glomerular disease in mice.

Ooi JD, Gan PY, Odobasic D, Holdsworth SR, Kitching AR.

Curr Protoc Immunol. 2014 Nov 3;107:15.27.1-15.27.19. doi: 10.1002/0471142735.im1527s107. Review.


Glomerulonephritis Induced by Heterologous Anti-GBM Globulin as a Planted Foreign Antigen.

Odobasic D, Ghali JR, O'Sullivan KM, Holdsworth SR, Kitching AR.

Curr Protoc Immunol. 2014 Aug 1;106:15.26.1-15.26.20. doi: 10.1002/0471142735.im1526s106. Review.


FcγRIIB regulates T-cell autoreactivity, ANCA production, and neutrophil activation to suppress anti-myeloperoxidase glomerulonephritis.

Ooi JD, Gan PY, Chen T, Eggenhuizen PJ, Chang J, Alikhan MA, Odobasic D, Holdsworth SR, Kitching AR.

Kidney Int. 2014 Dec;86(6):1140-9. doi: 10.1038/ki.2014.189. Epub 2014 May 28.


Endogenous myeloperoxidase is a mediator of joint inflammation and damage in experimental arthritis.

Odobasic D, Yang Y, Muljadi RC, O'Sullivan KM, Kao W, Smith M, Morand EF, Holdsworth SR.

Arthritis Rheumatol. 2014 Apr;66(4):907-17. doi: 10.1002/art.38299.


Innate IL-17A-producing leukocytes promote acute kidney injury via inflammasome and Toll-like receptor activation.

Chan AJ, Alikhan MA, Odobasic D, Gan PY, Khouri MB, Steinmetz OM, Mansell AS, Kitching AR, Holdsworth SR, Summers SA.

Am J Pathol. 2014 May;184(5):1411-8. doi: 10.1016/j.ajpath.2014.01.023. Epub 2014 Mar 14.


Endogenous interleukin (IL)-17A promotes pristane-induced systemic autoimmunity and lupus nephritis induced by pristane.

Summers SA, Odobasic D, Khouri MB, Steinmetz OM, Yang Y, Holdsworth SR, Kitching AR.

Clin Exp Immunol. 2014 Jun;176(3):341-50. doi: 10.1111/cei.12287.


Neutrophil myeloperoxidase regulates T-cell-driven tissue inflammation in mice by inhibiting dendritic cell function.

Odobasic D, Kitching AR, Yang Y, O'Sullivan KM, Muljadi RC, Edgtton KL, Tan DS, Summers SA, Morand EF, Holdsworth SR.

Blood. 2013 May 16;121(20):4195-204. doi: 10.1182/blood-2012-09-456483. Epub 2013 Mar 18.


Mast cells contribute to peripheral tolerance and attenuate autoimmune vasculitis.

Gan PY, Summers SA, Ooi JD, O'Sullivan KM, Tan DS, Muljadi RC, Odobasic D, Kitching AR, Holdsworth SR.

J Am Soc Nephrol. 2012 Dec;23(12):1955-66. doi: 10.1681/ASN.2012060572. Epub 2012 Nov 8.


Signal transducer and activation of transcription 6 (STAT6) regulates T helper type 1 (Th1) and Th17 nephritogenic immunity in experimental crescentic glomerulonephritis.

Summers SA, Phoon RK, Odobasic D, Dewage L, Kitching AR, Holdsworth SR.

Clin Exp Immunol. 2011 Nov;166(2):227-34. doi: 10.1111/j.1365-2249.2011.04437.x.


Interleukin-17A promotes early but attenuates established disease in crescentic glomerulonephritis in mice.

Odobasic D, Gan PY, Summers SA, Semple TJ, Muljadi RC, Iwakura Y, Kitching AR, Holdsworth SR.

Am J Pathol. 2011 Sep;179(3):1188-98. doi: 10.1016/j.ajpath.2011.05.039. Epub 2011 Jul 8.


Toll-like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll-like receptor 9 drives Th1 autoimmunity in murine vasculitis.

Summers SA, Steinmetz OM, Gan PY, Ooi JD, Odobasic D, Kitching AR, Holdsworth SR.

Arthritis Rheum. 2011 Apr;63(4):1124-35. doi: 10.1002/art.30208.


TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy.

Summers SA, Hoi A, Steinmetz OM, O'Sullivan KM, Ooi JD, Odobasic D, Akira S, Kitching AR, Holdsworth SR.

J Autoimmun. 2010 Dec;35(4):291-8. doi: 10.1016/j.jaut.2010.05.004.


T-bet deficiency attenuates renal injury in experimental crescentic glomerulonephritis.

Phoon RK, Kitching AR, Odobasic D, Jones LK, Semple TJ, Holdsworth SR.

J Am Soc Nephrol. 2008 Mar;19(3):477-85. doi: 10.1681/ASN.2007030392. Epub 2008 Jan 30.


Distinct in vivo roles of CD80 and CD86 in the effector T-cell responses inducing antigen-induced arthritis.

Odobasic D, Leech MT, Xue JR, Holdsworth SR.

Immunology. 2008 Aug;124(4):503-13. doi: 10.1111/j.1365-2567.2007.02802.x. Epub 2008 Jan 24.


Endogenous myeloperoxidase promotes neutrophil-mediated renal injury, but attenuates T cell immunity inducing crescentic glomerulonephritis.

Odobasic D, Kitching AR, Semple TJ, Holdsworth SR.

J Am Soc Nephrol. 2007 Mar;18(3):760-70. Epub 2007 Jan 31.


Anti-neutrophil cytoplasmic antibodies and effector CD4+ cells play nonredundant roles in anti-myeloperoxidase crescentic glomerulonephritis.

Ruth AJ, Kitching AR, Kwan RY, Odobasic D, Ooi JD, Timoshanko JR, Hickey MJ, Holdsworth SR.

J Am Soc Nephrol. 2006 Jul;17(7):1940-9. Epub 2006 Jun 12.


Inducible co-stimulatory molecule ligand is protective during the induction and effector phases of crescentic glomerulonephritis.

Odobasic D, Kitching AR, Semple TJ, Holdsworth SR.

J Am Soc Nephrol. 2006 Apr;17(4):1044-53. Epub 2006 Mar 15.


The isolation and purification of biologically active recombinant and native autoantigens for the study of autoimmune disease.

Apostolopoulos J, Ooi JD, Odobasic D, Holdsworth SR, Kitching AR.

J Immunol Methods. 2006 Jan 20;308(1-2):167-78. Epub 2005 Dec 9.


CD80 and CD86 costimulatory molecules regulate crescentic glomerulonephritis by different mechanisms.

Odobasic D, Kitching AR, Tipping PG, Holdsworth SR.

Kidney Int. 2005 Aug;68(2):584-94.


Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis.

Odobasic D, Kitching AR, Semple TJ, Timoshanko JR, Tipping PG, Holdsworth SR.

J Am Soc Nephrol. 2005 Jul;16(7):2012-22. Epub 2005 Jun 8.


IL-12p40 and IL-18 in crescentic glomerulonephritis: IL-12p40 is the key Th1-defining cytokine chain, whereas IL-18 promotes local inflammation and leukocyte recruitment.

Kitching AR, Turner AL, Wilson GR, Semple T, Odobasic D, Timoshanko JR, O'Sullivan KM, Tipping PG, Takeda K, Akira S, Holdsworth SR.

J Am Soc Nephrol. 2005 Jul;16(7):2023-33. Epub 2005 May 11.

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