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Items: 1 to 50 of 157

1.

Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity.

Rossi A, Dupaty L, Aillot L, Zhang L, Gallien C, Hallek M, Odenthal M, Adriouch S, Salvetti A, Büning H.

Sci Rep. 2019 Mar 6;9(1):3631. doi: 10.1038/s41598-019-40071-1.

2.

Pulmonary arterial remodelling by deficiency of peroxisome proliferator-activated receptor-γ in murine vascular smooth muscle cells occurs independently of obesity-related pulmonary hypertension.

Caglayan E, Trappiel M, Behringer A, Berghausen EM, Odenthal M, Wellnhofer E, Kappert K.

Respir Res. 2019 Feb 27;20(1):42. doi: 10.1186/s12931-019-1003-4.

3.

Selective Capture and Purification of MicroRNAs and Intracellular Proteins through Antisense-vectorized Magnetic Nanobeads.

Gessner I, Yu X, Jüngst C, Klimpel A, Wang L, Fischer T, Neundorf I, Schauss AC, Odenthal M, Mathur S.

Sci Rep. 2019 Feb 14;9(1):2069. doi: 10.1038/s41598-019-39575-7.

4.

LSD1 inhibition attenuates tumor growth by disrupting PLK1 mitotic pathway.

Dalvi PS, Macheleidt IF, Lim SY, Meemboor S, Muller M, Eischeid-Scholz H, Schaefer SC, Buettner R, Klein S, Odenthal M.

Mol Cancer Res. 2019 Feb 13. pii: molcanres.0971.2018. doi: 10.1158/1541-7786.MCR-18-0971. [Epub ahead of print]

PMID:
30760542
5.

Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells.

Mariappan A, Soni K, Schorpp K, Zhao F, Minakar A, Zheng X, Mandad S, Macheleidt I, Ramani A, Kubelka T, Dawidowski M, Golfmann K, Wason A, Yang C, Simons J, Schmalz HG, Hyman AA, Aneja R, Ullrich R, Urlaub H, Odenthal M, Büttner R, Li H, Sattler M, Hadian K, Gopalakrishnan J.

EMBO J. 2019 Jan 15;38(2). pii: e99876. doi: 10.15252/embj.201899876. Epub 2018 Dec 10.

6.

Author Correction: LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells.

Lim SY, Macheleidt I, Dalvi P, Schäfer SC, Kerick M, Ozretić L, Ortiz-Cuaran S, George J, Merkelbach-Bruse S, Wolf J, Timmermann B, Thomas RK, Schweiger MR, Buettner R, Odenthal M.

Sci Rep. 2018 Nov 1;8(1):16452. doi: 10.1038/s41598-018-31451-0.

7.

Hepatitis B virus promotes β-catenin-signalling and disassembly of adherens junctions in a Src kinase dependent fashion.

von Olshausen G, Quasdorff M, Bester R, Arzberger S, Ko C, van de Klundert M, Zhang K, Odenthal M, Ringelhan M, Niessen CM, Protzer U.

Oncotarget. 2018 Sep 21;9(74):33947-33960. doi: 10.18632/oncotarget.26103. eCollection 2018 Sep 21.

8.

Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations.

Macheleidt IF, Dalvi PS, Lim SY, Meemboor S, Meder L, Käsgen O, Müller M, Kleemann K, Wang L, Nürnberg P, Rüsseler V, Schäfer SC, Mahabir E, Büttner R, Odenthal M.

Mol Oncol. 2018 Nov;12(11):1965-1979. doi: 10.1002/1878-0261.12382. Epub 2018 Oct 13.

9.

ESR1-promoter-methylation status in primary breast cancer and its corresponding metastases.

Kirn V, Strake L, Thangarajah F, Richters L, Eischeid H, Koitzsch U, Odenthal M, Fries J.

Clin Exp Metastasis. 2018 Oct;35(7):707-712. doi: 10.1007/s10585-018-9935-5. Epub 2018 Sep 1.

PMID:
30173322
10.

Novel functional role of GH/IGF-I in neonatal lung myofibroblasts and in rat lung growth after intrauterine growth restriction.

Nawabi J, Vohlen C, Dinger K, Thangaratnarajah C, Klaudt C, Lopez Garcia E, Hirani DV, Karakaya PH, Macheleidt I, Odenthal M, Nüsken KD, Dötsch J, Alejandre Alcazar MA.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L623-L637. doi: 10.1152/ajplung.00413.2017. Epub 2018 Jul 26.

PMID:
30047284
11.

Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance.

Grasse S, Lienhard M, Frese S, Kerick M, Steinbach A, Grimm C, Hussong M, Rolff J, Becker M, Dreher F, Schirmer U, Boerno S, Ramisch A, Leschber G, Timmermann B, Grohé C, Lüders H, Vingron M, Fichtner I, Klein S, Odenthal M, Büttner R, Lehrach H, Sültmann H, Herwig R, Schweiger MR.

Genome Med. 2018 Jul 20;10(1):55. doi: 10.1186/s13073-018-0562-1.

12.

Autochthonous acute hepatitis E mimicking CMV infection.

Klein S, Fangman L, Kruis W, Dienes HP, Odenthal M, Drebber U.

Clin Res Hepatol Gastroenterol. 2018 Sep;42(4):e63-e65. doi: 10.1016/j.clinre.2017.12.002. Epub 2018 Jun 11. No abstract available.

PMID:
29903610
13.

Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer.

Meder L, Schuldt P, Thelen M, Schmitt A, Dietlein F, Klein S, Borchmann S, Wennhold K, Vlasic I, Oberbeck S, Riedel R, Florin A, Golfmann K, Schlößer HA, Odenthal M, Buettner R, Wolf J, Hallek M, Herling M, von Bergwelt-Baildon M, Reinhardt HC, Ullrich RT.

Cancer Res. 2018 Aug 1;78(15):4270-4281. doi: 10.1158/0008-5472.CAN-17-2176. Epub 2018 May 18.

PMID:
29776963
14.

LIN28B enhanced tumorigenesis in an autochthonous KRASG12V-driven lung carcinoma mouse model.

Meder L, König K, Dietlein F, Macheleidt I, Florin A, Ercanoglu MS, Rommerscheidt-Fuss U, Koker M, Schön G, Odenthal M, Klein F, Büttner R, Schulte JH, Heukamp LC, Ullrich RT.

Oncogene. 2018 May;37(20):2746-2756. doi: 10.1038/s41388-018-0158-7. Epub 2018 Mar 5.

PMID:
29503447
15.

microRNA-200a: A stage-dependent biomarker and predictor of steatosis and liver cell injury in human immunodeficiency virus patients.

Austermann C, Schierwagen R, Mohr R, Anadol E, Klein S, Pohlmann A, Jansen C, Strassburg CP, Schwarze-Zander C, Boesecke C, Rockstroh JK, Odenthal M, Trebicka J.

Hepatol Commun. 2017 Feb 27;1(1):36-45. doi: 10.1002/hep4.1017. eCollection 2017 Feb.

16.

Notch signaling triggers the tumor heterogeneity of small cell lung cancer.

Meder L, Büttner R, Odenthal M.

J Thorac Dis. 2017 Dec;9(12):4884-4888. doi: 10.21037/jtd.2017.11.104. No abstract available.

17.

Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS).

Horpaopan S, Kirfel J, Peters S, Kloth M, Hüneburg R, Altmüller J, Drichel D, Odenthal M, Kristiansen G, Strassburg C, Nattermann J, Hoffmann P, Nürnberg P, Büttner R, Thiele H, Kahl P, Spier I, Aretz S.

Hered Cancer Clin Pract. 2017 Nov 29;15:22. doi: 10.1186/s13053-017-0082-9. eCollection 2017.

18.

Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome.

Amer W, Toth C, Vassella E, Meinrath J, Koitzsch U, Arens A, Huang J, Eischeid H, Adam A, Buettner R, Scheel A, Schaefer SC, Odenthal M.

Sci Rep. 2017 Sep 11;7(1):11069. doi: 10.1038/s41598-017-11345-3.

19.

LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells.

Lim SY, Macheleidt I, Dalvi P, Schäfer SC, Kerick M, Ozretić L, Ortiz-Cuaran S, George J, Merkelbach-Bruse S, Wolf J, Timmermann B, Thomas RK, Schweiger MR, Buettner R, Odenthal M.

Sci Rep. 2017 Aug 31;7(1):10292. doi: 10.1038/s41598-017-09554-x. Erratum in: Sci Rep. 2018 Nov 1;8(1):16452.

20.

Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome.

Binder H, Hopp L, Schweiger MR, Hoffmann S, Jühling F, Kerick M, Timmermann B, Siebert S, Grimm C, Nersisyan L, Arakelyan A, Herberg M, Buske P, Loeffler-Wirth H, Rosolowski M, Engel C, Przybilla J, Peifer M, Friedrichs N, Moeslein G, Odenthal M, Hussong M, Peters S, Holzapfel S, Nattermann J, Hueneburg R, Schmiegel W, Royer-Pokora B, Aretz S, Kloth M, Kloor M, Buettner R, Galle J, Loeffler M.

J Pathol. 2017 Oct;243(2):242-254. doi: 10.1002/path.4948. Epub 2017 Sep 5.

PMID:
28727142
21.

The relevance of the lymph node ratio as predictor of prognosis is higher in HPV-negative than in HPV-positive oropharyngeal squamous cell carcinoma.

Meyer MF, Meinrath J, Seehawer J, Lechner A, Odenthal M, Quaas A, Semrau R, Huebbers CU, Marnitz S, Büttner R, Beutner D.

Clin Otolaryngol. 2018 Feb;43(1):192-198. doi: 10.1111/coa.12938. Epub 2017 Aug 14.

PMID:
28714274
22.

Use of the GeneReader NGS System in a clinical pathology laboratory: a comparative study.

Koitzsch U, Heydt C, Attig H, Immerschitt I, Merkelbach-Bruse S, Fammartino A, Büttner RH, Kong Y, Odenthal M.

J Clin Pathol. 2017 Aug;70(8):725-728. doi: 10.1136/jclinpath-2017-204342. Epub 2017 Apr 11.

23.

Exosomes as miRNA Carriers: Formation-Function-Future.

Yu X, Odenthal M, Fries JW.

Int J Mol Sci. 2016 Dec 2;17(12). pii: E2028. Review.

24.

Hepatitis C virus infection triggers a tumor-like glutamine metabolism.

Lévy PL, Duponchel S, Eischeid H, Molle J, Michelet M, Diserens G, Vermathen M, Vermathen P, Dufour JF, Dienes HP, Steffen HM, Odenthal M, Zoulim F, Bartosch B.

Hepatology. 2017 Mar;65(3):789-803. doi: 10.1002/hep.28949. Epub 2017 Feb 3.

25.

MDM2 and CDK4 amplifications are rare events in salivary duct carcinomas.

Grünewald I, Trautmann M, Busch A, Bauer L, Huss S, Schweinshaupt P, Vollbrecht C, Odenthal M, Quaas A, Büttner R, Meyer MF, Beutner D, Hüttenbrink KB, Wardelmann E, Stenner M, Hartmann W.

Oncotarget. 2016 Nov 15;7(46):75261-75272. doi: 10.18632/oncotarget.12127.

26.

Human Ex-Vivo Liver Model for Acetaminophen-induced Liver Damage.

Schreiter T, Sowa JP, Schlattjan M, Treckmann J, Paul A, Strucksberg KH, Baba HA, Odenthal M, Gieseler RK, Gerken G, Arteel GE, Canbay A.

Sci Rep. 2016 Aug 23;6:31916. doi: 10.1038/srep31916.

27.

Prediction of outcome by lymph node ratio in patients with parotid gland cancer.

Meyer MF, Kreppel M, Meinrath J, Grünewald I, Stenner M, Drebber U, Quaas A, Odenthal M, Semrau R, Huebbers CU, Zöller J, Huettenbrink KB, Buettner R, Beutner D.

Clin Otolaryngol. 2017 Feb;42(1):98-103. doi: 10.1111/coa.12672. Epub 2016 May 30.

PMID:
27185037
28.

B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice.

Knittel G, Liedgens P, Korovkina D, Seeger JM, Al-Baldawi Y, Al-Maarri M, Fritz C, Vlantis K, Bezhanova S, Scheel AH, Wolz OO, Reimann M, Möller P, López C, Schlesner M, Lohneis P, Weber AN, Trümper L; German International Cancer Genome Consortium Molecular Mechanisms in Malignant Lymphoma by Sequencing Project Consortium, Staudt LM, Ortmann M, Pasparakis M, Siebert R, Schmitt CA, Klatt AR, Wunderlich FT, Schäfer SC, Persigehl T, Montesinos-Rongen M, Odenthal M, Büttner R, Frenzel LP, Kashkar H, Reinhardt HC.

Blood. 2016 Jun 2;127(22):2732-41. doi: 10.1182/blood-2015-11-684183. Epub 2016 Apr 5.

29.

MDM2 gene amplification in esophageal carcinoma.

Michalk M, Meinrath J, Künstlinger H, Koitzsch U, Drebber U, Merkelbach-Bruse S, Bollschweiler E, Kloth M, Hartmann W, Hölscher A, Quaas A, Grimminger PP, Odenthal M.

Oncol Rep. 2016 Apr;35(4):2223-7. doi: 10.3892/or.2016.4578. Epub 2016 Jan 20.

PMID:
26796597
30.

Pioglitazone alleviates cardiac and vascular remodelling and improves survival in monocrotaline induced pulmonary arterial hypertension.

Behringer A, Trappiel M, Berghausen EM, Ten Freyhaus H, Wellnhofer E, Odenthal M, Blaschke F, Er F, Gassanov N, Rosenkranz S, Baldus S, Kappert K, Caglayan E.

Naunyn Schmiedebergs Arch Pharmacol. 2016 Apr;389(4):369-79. doi: 10.1007/s00210-015-1205-3. Epub 2016 Jan 7.

PMID:
26742933
31.

Serum microRNA profiles as prognostic or predictive markers in the multimodality treatment of patients with gastric cancer.

Sisic L, Vallböhmer D, Stoecklein NH, Blank S, Schmidt T, Driemel C, Möhlendick B, Knoefel WT, Odenthal M, Ott K.

Oncol Lett. 2015 Aug;10(2):869-874. Epub 2015 Jun 9.

32.

Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling.

Rastetter RH, Blömacher M, Drebber U, Marko M, Behrens J, Solga R, Hojeili S, Bhattacharya K, Wunderlich CM, Wunderlich FT, Odenthal M, Ziemann A, Eichinger L, Clemen CS.

BMC Cancer. 2015 Sep 15;15:638. doi: 10.1186/s12885-015-1645-7.

33.

Micro RNAs mir-106a, mir-122 and mir-197 are increased in severe acute viral hepatitis with coagulopathy.

Weseslindtner L, Macheleidt I, Eischeid H, Strassl R, Hofer H, Popow-Kraupp T, Dienes HP, Holzmann H, Odenthal M.

Liver Int. 2016 Mar;36(3):353-60. doi: 10.1111/liv.12961. Epub 2015 Oct 3.

PMID:
26352910
34.

Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients.

König K, Peifer M, Fassunke J, Ihle MA, Künstlinger H, Heydt C, Stamm K, Ueckeroth F, Vollbrecht C, Bos M, Gardizi M, Scheffler M, Nogova L, Leenders F, Albus K, Meder L, Becker K, Florin A, Rommerscheidt-Fuss U, Altmüller J, Kloth M, Nürnberg P, Henkel T, Bikár SE, Sos ML, Geese WJ, Strauss L, Ko YD, Gerigk U, Odenthal M, Zander T, Wolf J, Merkelbach-Bruse S, Buettner R, Heukamp LC.

J Thorac Oncol. 2015 Jul;10(7):1049-57. doi: 10.1097/JTO.0000000000000570.

35.

Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing.

Vollbrecht C, Mairinger FD, Koitzsch U, Peifer M, Koenig K, Heukamp LC, Crispatzu G, Wilden L, Kreuzer KA, Hallek M, Odenthal M, Herling CD, Buettner R.

PLoS One. 2015 Jun 8;10(6):e0129544. doi: 10.1371/journal.pone.0129544. eCollection 2015.

36.

Targeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity.

Grünewald I, Vollbrecht C, Meinrath J, Meyer MF, Heukamp LC, Drebber U, Quaas A, Beutner D, Hüttenbrink KB, Wardelmann E, Hartmann W, Büttner R, Odenthal M, Stenner M.

Oncotarget. 2015 Jul 20;6(20):18224-37.

37.

Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer.

Kloth M, Ruesseler V, Engel C, Koenig K, Peifer M, Mariotti E, Kuenstlinger H, Florin A, Rommerscheidt-Fuss U, Koitzsch U, Wodtke C, Ueckeroth F, Holzapfel S, Aretz S, Propping P, Loeffler M, Merkelbach-Bruse S, Odenthal M, Friedrichs N, Heukamp LC, Zander T, Buettner R.

Gut. 2016 Aug;65(8):1296-305. doi: 10.1136/gutjnl-2014-309026. Epub 2015 Apr 28.

PMID:
26001389
38.

Impact of the MRN Complex on Adeno-Associated Virus Integration and Replication during Coinfection with Herpes Simplex Virus 1.

Millet R, Jolinon N, Nguyen XN, Berger G, Cimarelli A, Greco A, Bertrand P, Odenthal M, Büning H, Salvetti A.

J Virol. 2015 Jul;89(13):6824-34. doi: 10.1128/JVI.00171-15. Epub 2015 Apr 22.

39.

Massively parallel sequencing fails to detect minor resistant subclones in tissue samples prior to tyrosine kinase inhibitor therapy.

Heydt C, Kumm N, Fassunke J, Künstlinger H, Ihle MA, Scheel A, Schildhaus HU, Haller F, Büttner R, Odenthal M, Wardelmann E, Merkelbach-Bruse S.

BMC Cancer. 2015 Apr 15;15:291. doi: 10.1186/s12885-015-1311-0.

40.

Circulating miRNA-122 levels are associated with hepatic necroinflammation and portal hypertension in HIV/HCV coinfection.

Jansen C, Reiberger T, Huang J, Eischeid H, Schierwagen R, Mandorfer M, Anadol E, Schwabl P, Schwarze-Zander C, Warnecke-Eberz U, Strassburg CP, Rockstroh JK, Peck-Radosavljevic M, Odenthal M, Trebicka J.

PLoS One. 2015 Feb 3;10(2):e0116768. doi: 10.1371/journal.pone.0116768. eCollection 2015.

41.

Glutathione peroxidase 4 is reversibly induced by HCV to control lipid peroxidation and to increase virion infectivity.

Brault C, Lévy P, Duponchel S, Michelet M, Sallé A, Pécheur EI, Plissonnier ML, Parent R, Véricel E, Ivanov AV, Demir M, Steffen HM, Odenthal M, Zoulim F, Bartosch B.

Gut. 2016 Jan;65(1):144-54. doi: 10.1136/gutjnl-2014-307904. Epub 2014 Dec 16.

PMID:
25516417
42.

Serum microRNA profiles as prognostic/predictive markers in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction.

Odenthal M, Hee J, Gockel I, Sisic L, Schmitz J, Stoecklein NH, Driemel C, Möhlendick B, Schmidt T, Knoefel WT, Lang H, Büttner R, Ott K, Vallböhmer D.

Int J Cancer. 2015 Jul 1;137(1):230-7. doi: 10.1002/ijc.29363. Epub 2014 Dec 3.

43.

FOXP1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma.

Ackermann S, Kocak H, Hero B, Ehemann V, Kahlert Y, Oberthuer A, Roels F, Theißen J, Odenthal M, Berthold F, Fischer M.

BMC Cancer. 2014 Nov 18;14:840. doi: 10.1186/1471-2407-14-840.

44.

Circulating microRNAs as a marker for liver injury in human immunodeficiency virus patients.

Anadol E, Schierwagen R, Elfimova N, Tack K, Schwarze-Zander C, Eischeid H, Noetel A, Boesecke C, Jansen C, Dold L, Wasmuth JC, Strassburg CP, Spengler U, Rockstroh JK, Odenthal M, Trebicka J.

Hepatology. 2015 Jan;61(1):46-55. doi: 10.1002/hep.27369. Epub 2014 Nov 20.

PMID:
25125218
45.

Comparison of pre-analytical FFPE sample preparation methods and their impact on massively parallel sequencing in routine diagnostics.

Heydt C, Fassunke J, Künstlinger H, Ihle MA, König K, Heukamp LC, Schildhaus HU, Odenthal M, Büttner R, Merkelbach-Bruse S.

PLoS One. 2014 Aug 8;9(8):e104566. doi: 10.1371/journal.pone.0104566. eCollection 2014.

46.

The role of miRNA-34a as a prognostic biomarker for cirrhotic patients with portal hypertension receiving TIPS.

Jansen C, Eischeid H, Goertzen J, Schierwagen R, Anadol E, Strassburg CP, Sauerbruch T, Odenthal M, Trebicka J.

PLoS One. 2014 Jul 28;9(7):e103779. doi: 10.1371/journal.pone.0103779. eCollection 2014.

47.

MicroRNA function in the profibrogenic interplay upon chronic liver disease.

Huang J, Yu X, Fries JW, Zhang L, Odenthal M.

Int J Mol Sci. 2014 May 27;15(6):9360-71. doi: 10.3390/ijms15069360. Review.

48.

Hepatitis E in liver biopsies from patients with acute hepatitis of clinically unexplained origin.

Drebber U, Odenthal M, Aberle SW, Winkel N, Wedemeyer I, Hemberger J, Holzmann H, Dienes HP.

Front Physiol. 2013 Dec 13;4:351. doi: 10.3389/fphys.2013.00351. eCollection 2013.

49.

Obesity resistance and deregulation of lipogenesis in Δ6-fatty acid desaturase (FADS2) deficiency.

Stoffel W, Hammels I, Jenke B, Binczek E, Schmidt-Soltau I, Brodesser S, Odenthal M, Thevis M.

EMBO Rep. 2014 Jan;15(1):110-20. doi: 10.1002/embr.201338041. Epub 2013 Dec 30.

50.

Comparison of TNM-based stage grouping versus UICC/AJCC stage grouping (7th edition) in malignant parotid gland tumors.

Kreppel M, Scheer M, Meyer M, Stenner M, Wedemeyer I, Drebber U, Semrau R, Odenthal M, Zöller JE, Guntinas-Lichius O, Büttner R, Beutner D.

Oral Oncol. 2013 Sep;49(9):903-910. doi: 10.1016/j.oraloncology.2013.06.009. Epub 2013 Jul 10.

PMID:
23850296

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