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Items: 22


Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function.

Fearnley GW, Abdul-Zani I, Latham AM, Hollstein MC, Ladbury JE, Wheatcroft SB, Odell AF, Ponnambalam S.

Biol Open. 2019 May 17;8(5). pii: bio034215. doi: 10.1242/bio.034215.


Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

Williams SP, Odell AF, Karnezis T, Farnsworth RH, Gould CM, Li J, Paquet-Fifield S, Harris NC, Walter A, Gregory JL, Lamont SF, Liu R, Takano EA, Nowell CJ, Bower NI, Resnick D, Smyth GK, Coultas L, Hogan BM, Fox SB, Mueller SN, Simpson KJ, Achen MG, Stacker SA.

Sci Signal. 2017 Oct 3;10(499). pii: eaal2987. doi: 10.1126/scisignal.aal2987.


Palladium-mediated 11C-carbonylations using aryl halides and cyanamide.

Nordeman P, Chow SY, Odell AF, Antoni G, Odell LR.

Org Biomol Chem. 2017 Jun 7;15(22):4875-4881. doi: 10.1039/c7ob01064h.


VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions.

Fearnley GW, Odell AF, Latham AM, Mughal NA, Bruns AF, Burgoyne NJ, Homer-Vanniasinkam S, Zachary IC, Hollstein MC, Wheatcroft SB, Ponnambalam S.

Mol Biol Cell. 2014 Aug 15;25(16):2509-21. doi: 10.1091/mbc.E14-05-0962. Epub 2014 Jun 25.


Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation.

Jopling HM, Odell AF, Pellet-Many C, Latham AM, Frankel P, Sivaprasadarao A, Walker JH, Zachary IC, Ponnambalam S.

Cells. 2014 Apr 29;3(2):363-85. doi: 10.3390/cells3020363.


Vascular endothelial growth factor A-stimulated signaling from endosomes in primary endothelial cells.

Fearnley GW, Smith GA, Odell AF, Latham AM, Wheatcroft SB, Harrison MA, Tomlinson DC, Ponnambalam S.

Methods Enzymol. 2014;535:265-92. doi: 10.1016/B978-0-12-397925-4.00016-X.


A novel p53 mutant found in iatrogenic urothelial cancers is dysfunctional and can be rescued by a second-site global suppressor mutation.

Odell AF, Odell LR, Askham JM, Alogheli H, Ponnambalam S, Hollstein M.

J Biol Chem. 2013 Jun 7;288(23):16704-14. doi: 10.1074/jbc.M112.443168. Epub 2013 Apr 23.


Expression of biologically active human colony stimulating factor-1 in Pichia pastoris.

Mashkani B, Odell AF, Byrnes EM, Griffith R, Ashman LK.

Protein Expr Purif. 2013 Mar;88(1):93-7. doi: 10.1016/j.pep.2012.11.017. Epub 2012 Dec 12.


The S100A6 calcium-binding protein regulates endothelial cell-cycle progression and senescence.

Bao L, Odell AF, Stephen SL, Wheatcroft SB, Walker JH, Ponnambalam S.

FEBS J. 2012 Dec;279(24):4576-88. doi: 10.1111/febs.12044. Epub 2012 Nov 22.


A biphasic endothelial stress-survival mechanism regulates the cellular response to vascular endothelial growth factor A.

Latham AM, Odell AF, Mughal NA, Issitt T, Ulyatt C, Walker JH, Homer-Vanniasinkam S, Ponnambalam S.

Exp Cell Res. 2012 Nov 1;318(18):2297-311. doi: 10.1016/j.yexcr.2012.06.023. Epub 2012 Jul 11.


Efficient introduction of specific TP53 mutations into mouse embryonic fibroblasts and embryonic stem cells.

Wei QX, van der Hoeven F, Hollstein M, Odell AF.

Nat Protoc. 2012 May 17;7(6):1145-60. doi: 10.1038/nprot.2012.042.


A VE-cadherin-PAR3-α-catenin complex regulates the Golgi localization and activity of cytosolic phospholipase A(2)α in endothelial cells.

Odell AF, Hollstein M, Ponnambalam S, Walker JH.

Mol Biol Cell. 2012 May;23(9):1783-96. doi: 10.1091/mbc.E11-08-0694. Epub 2012 Mar 7.


Rapid derivation of genetically related mutants from embryonic cells harboring a recombinase-specific Trp53 platform.

Wei QX, Odell AF, van der Hoeven F, Hollstein M.

Cell Cycle. 2011 Apr 15;10(8):1261-70. Epub 2011 Apr 15.


Wild-type and Hupki (human p53 knock-in) murine embryonic fibroblasts: p53/ARF pathway disruption in spontaneous escape from senescence.

Whibley C, Odell AF, Nedelko T, Balaburski G, Murphy M, Liu Z, Stevens L, Walker JH, Routledge M, Hollstein M.

J Biol Chem. 2010 Apr 9;285(15):11326-35. doi: 10.1074/jbc.M109.064444. Epub 2010 Jan 29.


Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis.

Bruns AF, Herbert SP, Odell AF, Jopling HM, Hooper NM, Zachary IC, Walker JH, Ponnambalam S.

Traffic. 2010 Jan;11(1):161-74. doi: 10.1111/j.1600-0854.2009.01001.x.


Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells.

Jopling HM, Odell AF, Hooper NM, Zachary IC, Walker JH, Ponnambalam S.

Arterioscler Thromb Vasc Biol. 2009 Jul;29(7):1119-24. doi: 10.1161/ATVBAHA.109.186239. Epub 2009 Apr 16.


Activation of cytosolic phospholipase A2-{alpha} as a novel mechanism regulating endothelial cell cycle progression and angiogenesis.

Herbert SP, Odell AF, Ponnambalam S, Walker JH.

J Biol Chem. 2009 Feb 27;284(9):5784-96. doi: 10.1074/jbc.M807282200. Epub 2009 Jan 1.


The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels.

Odell AF, Van Helden DF, Scott JL.

J Biol Chem. 2008 Feb 15;283(7):4395-407. Epub 2007 Nov 29.


The confluence-dependent interaction of cytosolic phospholipase A2-alpha with annexin A1 regulates endothelial cell prostaglandin E2 generation.

Herbert SP, Odell AF, Ponnambalam S, Walker JH.

J Biol Chem. 2007 Nov 23;282(47):34468-78. Epub 2007 Sep 16.


Resistance to c-KIT kinase inhibitors conferred by V654A mutation.

Roberts KG, Odell AF, Byrnes EM, Baleato RM, Griffith R, Lyons AB, Ashman LK.

Mol Cancer Ther. 2007 Mar;6(3):1159-66.


Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4.

Odell AF, Scott JL, Van Helden DF.

J Biol Chem. 2005 Nov 11;280(45):37974-87. Epub 2005 Sep 6.



Odell AF.

Science. 1921 Oct 14;54(1398):357. No abstract available.


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