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Items: 1 to 50 of 393

1.

A combined in silico and in vitro study on mouse Serpina1a antitrypsin-deficiency mutants.

Eggenschwiler R, Patronov A, Hegermann J, Fráguas-Eggenschwiler M, Wu G, Cortnumme L, Ochs M, Antes I, Cantz T.

Sci Rep. 2019 May 16;9(1):7486. doi: 10.1038/s41598-019-44043-3.

2.

Flow cytometric analysis of the leukocyte landscape during bleomycin-induced lung injury and fibrosis in the rat.

Kloth C, Gruben N, Ochs M, Knudsen L, Lopez-Rodriguez E.

Am J Physiol Lung Cell Mol Physiol. 2019 Jul 1;317(1):L109-L126. doi: 10.1152/ajplung.00176.2018. Epub 2019 May 1.

PMID:
31042078
3.

Lung growth after pneumonectomy: searching for the right stimuli.

Ochs M.

Am J Physiol Lung Cell Mol Physiol. 2019 May 1;316(5):L934-L935. doi: 10.1152/ajplung.00119.2019. Epub 2019 Mar 20. No abstract available.

PMID:
30892075
4.

Brain activity during reciprocal social interaction investigated using conversational robots as control condition.

Rauchbauer B, Nazarian B, Bourhis M, Ochs M, Prévot L, Chaminade T.

Philos Trans R Soc Lond B Biol Sci. 2019 Apr 29;374(1771):20180033. doi: 10.1098/rstb.2018.0033.

PMID:
30852994
5.

On the Topological Complexity of Human Alveolar Epithelial Type 1 Cells.

Schneider JP, Wrede C, Hegermann J, Weibel ER, Mühlfeld C, Ochs M.

Am J Respir Crit Care Med. 2019 May 1;199(9):1153-1156. doi: 10.1164/rccm.201810-1866LE. No abstract available.

6.

Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis.

Beike L, Wrede C, Hegermann J, Lopez-Rodriguez E, Kloth C, Gauldie J, Kolb M, Maus UA, Ochs M, Knudsen L.

Lab Invest. 2019 Jun;99(6):830-852. doi: 10.1038/s41374-019-0189-x. Epub 2019 Jan 30.

PMID:
30700849
7.

Cellular and acellular ex vivo lung perfusion preserve functional lung ultrastructure in a large animal model: a stereological study.

Steinmeyer J, Becker S, Avsar M, Salman J, Höffler K, Haverich A, Warnecke G, Mühlfeld C, Ochs M, Schnapper-Isl A.

Respir Res. 2018 Dec 4;19(1):238. doi: 10.1186/s12931-018-0942-5.

8.

The micromechanics of lung alveoli: structure and function of surfactant and tissue components.

Knudsen L, Ochs M.

Histochem Cell Biol. 2018 Dec;150(6):661-676. doi: 10.1007/s00418-018-1747-9. Epub 2018 Nov 2. Review.

9.

Cardiovascular magnetic resonance of cardiac morphology and function: impact of different strategies of contour drawing and indexing.

Riffel JH, Schmucker K, Andre F, Ochs M, Hirschberg K, Schaub E, Fritz T, Mueller-Hennessen M, Giannitsis E, Katus HA, Friedrich MG.

Clin Res Cardiol. 2019 Apr;108(4):411-429. doi: 10.1007/s00392-018-1371-7. Epub 2018 Sep 10.

PMID:
30203190
10.

Enter the Matrix: Factorization Uncovers Knowledge from Omics.

Stein-O'Brien GL, Arora R, Culhane AC, Favorov AV, Garmire LX, Greene CS, Goff LA, Li Y, Ngom A, Ochs MF, Xu Y, Fertig EJ.

Trends Genet. 2018 Oct;34(10):790-805. doi: 10.1016/j.tig.2018.07.003. Epub 2018 Aug 22. Review.

11.

Alveolar Micromechanics in Bleomycin-induced Lung Injury.

Knudsen L, Lopez-Rodriguez E, Berndt L, Steffen L, Ruppert C, Bates JHT, Ochs M, Smith BJ.

Am J Respir Cell Mol Biol. 2018 Dec;59(6):757-769. doi: 10.1165/rcmb.2018-0044OC.

PMID:
30095988
12.

Echocardiographic calcification score in patients with low/intermediate cardiovascular risk.

Hirschberg K, Reinhart M, Mereles D, Uhlmann L, André F, Riffel J, Ochs M, Katus HA.

Clin Res Cardiol. 2019 Feb;108(2):194-202. doi: 10.1007/s00392-018-1343-y. Epub 2018 Aug 6.

PMID:
30083858
13.

The influence of age on valve disease in patients with varicose veins analysed by transmission electron microscopy and stereology.

Mouton WG, Wagner MO, Haenni B, Mouton KT, Ochs M, Tschanz SA.

Vasa. 2018 Aug;47(5):409-416. doi: 10.1024/0301-1526/a000714. Epub 2018 May 29.

14.

Hands-on or no hands-on training in ultrasound imaging: A randomized trial to evaluate learning outcomes and speed of recall of topographic anatomy.

Knudsen L, Nawrotzki R, Schmiedl A, Mühlfeld C, Kruschinski C, Ochs M.

Anat Sci Educ. 2018 Nov;11(6):575-591. doi: 10.1002/ase.1792. Epub 2018 Apr 23.

PMID:
29683560
15.

Recent developments in 3-D reconstruction and stereology to study the pulmonary vasculature.

Mühlfeld C, Wrede C, Knudsen L, Buchacker T, Ochs M, Grothausmann R.

Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L173-L183. doi: 10.1152/ajplung.00541.2017. Epub 2018 Apr 12.

PMID:
29644892
16.

Variability of cardiovascular magnetic resonance (CMR) T1 mapping parameters in healthy volunteers during long-term follow-up.

Aus dem Siepen F, Baumgärtner C, Müller-Henessen M, André F, Messroghli D, Ochs M, Riffel J, Giannitsis E, Katus HA, Friedrich MG, Buss SJ.

Open Heart. 2018 Feb 24;5(1):e000717. doi: 10.1136/openhrt-2017-000717. eCollection 2018.

17.

Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1.

van Westen E, Poelen MCM, van den Dobbelsteen GPJM, Oloo EO, Ochs MM, Rots NY, van Els CACM.

PLoS One. 2018 Mar 6;13(3):e0193650. doi: 10.1371/journal.pone.0193650. eCollection 2018.

18.

Quantitative Histology Seriously Flawed by Lack of Lung Volume Measurement.

Mitzner W, Ochs M.

Am J Respir Cell Mol Biol. 2018 Feb;58(2):273-274. doi: 10.1165/rcmb.2017-0380LE. No abstract available.

PMID:
29388832
19.

Splice Expression Variation Analysis (SEVA) for inter-tumor heterogeneity of gene isoform usage in cancer.

Afsari B, Guo T, Considine M, Florea L, Kagohara LT, Stein-O'Brien GL, Kelley D, Flam E, Zambo KD, Ha PK, Geman D, Ochs MF, Califano JA, Gaykalova DA, Favorov AV, Fertig EJ.

Bioinformatics. 2018 Jun 1;34(11):1859-1867. doi: 10.1093/bioinformatics/bty004.

20.

Stereological assessment of the blood-air barrier and the surfactant system after mesenchymal stem cell pretreatment in a porcine non-heart-beating donor model for lung transplantation.

Schnapper A, Christmann A, Knudsen L, Rahmanian P, Choi YH, Zeriouh M, Karavidic S, Neef K, Sterner-Kock A, Guschlbauer M, Hofmaier F, Maul AC, Wittwer T, Wahlers T, Mühlfeld C, Ochs M.

J Anat. 2018 Feb;232(2):283-295. doi: 10.1111/joa.12747. Epub 2017 Nov 28.

PMID:
29193065
21.

Antibodies to PcpA and PhtD protect mice against Streptococcus pneumoniae by a macrophage- and complement-dependent mechanism.

Visan L, Rouleau N, Proust E, Peyrot L, Donadieu A, Ochs M.

Hum Vaccin Immunother. 2018 Feb 1;14(2):489-494. doi: 10.1080/21645515.2017.1403698. Epub 2017 Dec 14.

22.

Regional differences in prognostic value of cardiac valve plane displacement in systemic light-chain amyloidosis.

Ochs MM, Fritz T, Arenja N, Riffel J, Andre F, Mereles D, Siepen FAD, Hegenbart U, Schönland S, Katus HA, Friedrich MGW, Buss SJ.

J Cardiovasc Magn Reson. 2017 Nov 9;19(1):87. doi: 10.1186/s12968-017-0402-2.

23.

Localization of Exogenous Mesenchymal Stem Cells in a Pig Model of Lung Transplantation.

Piatkowski T, Brandenberger C, Rahmanian P, Choi YH, Zeriouh M, Sabashnikov A, Wittwer T, Wahlers TCW, Ochs M, Mühlfeld C.

Thorac Cardiovasc Surg. 2018 Jan;66(1):63-70. doi: 10.1055/s-0037-1607051. Epub 2017 Oct 9.

PMID:
28992651
24.

Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.

Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, Traber K, Quinton LJ, Crane A, Davis BR, White FV, Wambach J, Whitsett JA, Cole FS, Morrisey EE, Guttentag SH, Beers MF, Kotton DN.

Cell Stem Cell. 2017 Oct 5;21(4):472-488.e10. doi: 10.1016/j.stem.2017.08.014. Epub 2017 Sep 28.

25.

EMX2 gene expression predicts liver metastasis and survival in colorectal cancer.

Aykut B, Ochs M, Radhakrishnan P, Brill A, Höcker H, Schwarz S, Weissinger D, Kehm R, Kulu Y, Ulrich A, Schneider M.

BMC Cancer. 2017 Aug 22;17(1):555. doi: 10.1186/s12885-017-3556-2.

26.

Trauma Surgery.

Ochs M, Chung W, Powers D.

J Oral Maxillofac Surg. 2017 Aug;75(8S):e151-e194. doi: 10.1016/j.joms.2017.04.023. No abstract available.

PMID:
28728729
27.

Evaluating optimal therapy robustness by virtual expansion of a sample population, with a case study in cancer immunotherapy.

Barish S, Ochs MF, Sontag ED, Gevertz JL.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6277-E6286. doi: 10.1073/pnas.1703355114. Epub 2017 Jul 17.

28.

A Critical Comment on a Recent Publication Using Parenchymal Airspace Profiling.

Knudsen L, Ochs M.

Am J Respir Cell Mol Biol. 2017 Jul;57(1):132. doi: 10.1165/rcmb.2017-0010LE. No abstract available.

PMID:
28665222
29.

Autophagy in kidney transplants of sirolimus treated recipients.

Bhayana S, Baisantry A, Kraemer TD, Wrede C, Hegermann J, Bräsen JH, Bockmeyer C, Ulrich Becker J, Ochs M, Gwinner W, Haller H, Melk A, Schmitt R.

J Nephropathol. 2017 Mar;6(2):90-96. doi: 10.15171/jnp.2017.15. Epub 2016 Oct 22.

30.

Surfactant replacement therapy reduces acute lung injury and collapse induration-related lung remodeling in the bleomycin model.

Steffen L, Ruppert C, Hoymann HG, Funke M, Ebener S, Kloth C, Mühlfeld C, Ochs M, Knudsen L, Lopez-Rodriguez E.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L313-L327. doi: 10.1152/ajplung.00033.2017. Epub 2017 Apr 27.

31.

Strengths and limitations of coronary angiography with turbo high-pitch third-generation dual-source CT.

Ochs MM, Andre F, Korosoglou G, Fritz T, Seitz S, Bogomazov Y, Schlett CL, Sokiranski R, Sommer A, Gückel F, Brado M, Kauczor HU, Görich J, Katus HA, Buss SJ.

Clin Radiol. 2017 Sep;72(9):739-744. doi: 10.1016/j.crad.2017.03.010. Epub 2017 Apr 8.

PMID:
28395916
32.

Lung remodeling in aging surfactant protein D deficient mice.

Schneider JP, Arkenau M, Knudsen L, Wedekind D, Ochs M.

Ann Anat. 2017 May;211:158-175. doi: 10.1016/j.aanat.2017.01.013. Epub 2017 Feb 7.

PMID:
28185902
33.

PatternMarkers & GWCoGAPS for novel data-driven biomarkers via whole transcriptome NMF.

Stein-O'Brien GL, Carey JL, Lee WS, Considine M, Favorov AV, Flam E, Guo T, Li S, Marchionni L, Sherman T, Sivy S, Gaykalova DA, McKay RD, Ochs MF, Colantuoni C, Fertig EJ.

Bioinformatics. 2017 Jun 15;33(12):1892-1894. doi: 10.1093/bioinformatics/btx058.

34.

Limits of the possible: diagnostic image quality in coronary angiography with third-generation dual-source CT.

Ochs MM, Siepen FAD, Fritz T, Andre F, Gitsioudis G, Korosoglou G, Seitz S, Bogomazov Y, Schlett CL, Sokiranski R, Sommer A, Gückel F, Brado M, Kauczor HU, Görich J, Friedrich MGW, Katus HA, Buss SJ.

Clin Res Cardiol. 2017 Jul;106(7):485-492. doi: 10.1007/s00392-017-1077-2. Epub 2017 Feb 6.

PMID:
28168514
35.

Myocardial contraction fraction derived from cardiovascular magnetic resonance cine images-reference values and performance in patients with heart failure and left ventricular hypertrophy.

Arenja N, Fritz T, Andre F, Riffel JH, Aus dem Siepen F, Ochs M, Paffhausen J, Hegenbart U, Schönland S, Müller-Hennessen M, Giannitsis E, Kristen AV, Katus HA, Friedrich MG, Buss SJ.

Eur Heart J Cardiovasc Imaging. 2017 Dec 1;18(12):1414-1422. doi: 10.1093/ehjci/jew324.

PMID:
28165128
36.

Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC.

Gaykalova DA, Zizkova V, Guo T, Tiscareno I, Wei Y, Vatapalli R, Hennessey PT, Ahn J, Danilova L, Khan Z, Bishop JA, Gutkind JS, Koch WM, Westra WH, Fertig EJ, Ochs MF, Califano JA.

Oncotarget. 2017 Feb 28;8(9):15349-15363. doi: 10.18632/oncotarget.14856.

37.

A comprehensive analysis of cardiac valve plane displacement in healthy adults: age-stratified normal values by cardiac magnetic resonance.

Ochs MM, Fritz T, André F, Riffel J, Mereles D, Müller-Hennessen M, Giannitsis E, Katus HA, Friedrich MG, Buss SJ.

Int J Cardiovasc Imaging. 2017 May;33(5):721-729. doi: 10.1007/s10554-016-1058-y. Epub 2017 Jan 21.

PMID:
28110433
38.

Development, remodeling and regeneration of the lung: coping with the structural and functional challenges of breathing.

Mühlfeld C, Ochs M.

Cell Tissue Res. 2017 Mar;367(3):407-411. doi: 10.1007/s00441-016-2568-6. No abstract available.

PMID:
28091774
39.

Anterior Aortic Plane Systolic Excursion: A Novel Indicator of Transplant-Free Survival in Systemic Light-Chain Amyloidosis.

Ochs MM, Riffel J, Kristen AV, Hegenbart U, Schönland S, Hardt SE, Katus HA, Mereles D, Buss SJ.

J Am Soc Echocardiogr. 2016 Dec;29(12):1188-1196. doi: 10.1016/j.echo.2016.09.003. Epub 2016 Oct 27.

PMID:
28042785
40.

Aberrant lung remodeling in a mouse model of surfactant dysregulation induced by modulation of the Abca3 gene.

Beers MF, Knudsen L, Tomer Y, Maronn J, Zhao M, Ochs M, Mulugeta S.

Ann Anat. 2017 Mar;210:135-146. doi: 10.1016/j.aanat.2016.11.015. Epub 2016 Dec 26.

41.

Tissue remodelling in pulmonary fibrosis.

Knudsen L, Ruppert C, Ochs M.

Cell Tissue Res. 2017 Mar;367(3):607-626. doi: 10.1007/s00441-016-2543-2. Epub 2016 Dec 16. Review.

PMID:
27981380
42.

In memoriam Joachim Richter (1941-2015).

Ochs M.

Ann Anat. 2016 Nov;208:A1-A3. doi: 10.1016/j.aanat.2016.06.003. Epub 2016 Jul 9. No abstract available.

PMID:
27926464
43.

The Caenorhabditis elegans NF2/Merlin Molecule NFM-1 Nonautonomously Regulates Neuroblast Migration and Interacts Genetically with the Guidance Cue SLT-1/Slit.

Josephson MP, Aliani R, Norris ML, Ochs ME, Gujar M, Lundquist EA.

Genetics. 2017 Feb;205(2):737-748. doi: 10.1534/genetics.116.191957. Epub 2016 Dec 2.

44.

Digital 3D reconstructions using histological serial sections of lung tissue including the alveolar capillary network.

Grothausmann R, Knudsen L, Ochs M, Mühlfeld C.

Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L243-L257. doi: 10.1152/ajplung.00326.2016. Epub 2016 Dec 2.

45.

A combined method for correlative 3D imaging of biological samples from macro to nano scale.

Kellner M, Heidrich M, Lorbeer RA, Antonopoulos GC, Knudsen L, Wrede C, Izykowski N, Grothausmann R, Jonigk D, Ochs M, Ripken T, Kühnel MP, Meyer H.

Sci Rep. 2016 Oct 19;6:35606. doi: 10.1038/srep35606.

46.

Using electron microscopes to look into the lung.

Ochs M, Knudsen L, Hegermann J, Wrede C, Grothausmann R, Mühlfeld C.

Histochem Cell Biol. 2016 Dec;146(6):695-707. doi: 10.1007/s00418-016-1502-z. Epub 2016 Sep 29. Review.

PMID:
27688057
47.

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network.

Fertig EJ, Ozawa H, Thakar M, Howard JD, Kagohara LT, Krigsfeld G, Ranaweera RS, Hughes RM, Perez J, Jones S, Favorov AV, Carey J, Stein-O'Brien G, Gaykalova DA, Ochs MF, Chung CH.

Oncotarget. 2016 Nov 8;7(45):73845-73864. doi: 10.18632/oncotarget.12075.

48.

Effect of irradiation/bone marrow transplantation on alveolar epithelial type II cells is aggravated in surfactant protein D deficient mice.

Mühlfeld C, Madsen J, Mackay RM, Schneider JP, Schipke J, Lutz D, Birkelbach B, Knudsen L, Botto M, Ochs M, Clark H.

Histochem Cell Biol. 2017 Jan;147(1):49-61. doi: 10.1007/s00418-016-1479-7. Epub 2016 Aug 26.

49.

Regulation of macroautophagy in amiodarone-induced pulmonary fibrosis.

Mahavadi P, Knudsen L, Venkatesan S, Henneke I, Hegermann J, Wrede C, Ochs M, Ahuja S, Chillappagari S, Ruppert C, Seeger W, Korfei M, Guenther A.

J Pathol Clin Res. 2015 Jun 3;1(4):252-63. doi: 10.1002/cjp2.20. eCollection 2015 Oct.

50.

A bivalent pneumococcal histidine triad protein D-choline-binding protein A vaccine elicits functional antibodies that passively protect mice from Streptococcus pneumoniae challenge.

Ochs MM, Williams K, Sheung A, Lheritier P, Visan L, Rouleau N, Proust E, de Montfort A, Tang M, Mari K, Hopfer R, Gallichan S, Brookes RH.

Hum Vaccin Immunother. 2016 Nov;12(11):2946-2952.

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