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Items: 1 to 50 of 336

1.

Extracellular vesicles and encapusulated miRNAs as emerging cancer biomarkers for novel liquid biopsy.

Yoshioka Y, Katsuda T, Ochiya T.

Jpn J Clin Oncol. 2018 Aug 28. doi: 10.1093/jjco/hyy120. [Epub ahead of print]

PMID:
30169666
2.

Extracellular microRNAs and oxidative stress in liver injury: a systematic mini review.

Matsuzaki J, Ochiya T.

J Clin Biochem Nutr. 2018 Jul;63(1):6-11. doi: 10.3164/jcbn.17-123. Epub 2018 Apr 11. Review.

3.

Fascin protein stabilization by miR-146a implicated in the process of a chronic inflammation-related colon carcinogenesis model.

Kanda Y, Kawaguchi T, Osaki M, Onuma K, Ochiya T, Kitagawa T, Okada F.

Inflamm Res. 2018 Oct;67(10):839-846. doi: 10.1007/s00011-018-1175-2. Epub 2018 Jul 28.

PMID:
30056535
4.

A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network.

Fujiwara Y, Saito M, Robles AI, Nishida M, Takeshita F, Watanabe M, Ochiya T, Yokota J, Kohno T, Harris CC, Tsuchiya N.

EBioMedicine. 2018 Jul;33:33-48. doi: 10.1016/j.ebiom.2018.06.031. Epub 2018 Jul 7.

5.

Screening of microRNAs for a repressor of hepatitis B virus replication.

Naito Y, Hamada-Tsutsumi S, Yamamoto Y, Kogure A, Yoshioka Y, Watashi K, Ochiya T, Tanaka Y.

Oncotarget. 2018 Jul 6;9(52):29857-29868. doi: 10.18632/oncotarget.25557. eCollection 2018 Jul 6.

6.

[MicroRNA in Body Fluids - Development of the Novel Plat Form for Cancer Therapeutics and Diagnosis].

Takahashi RU, Prieto-Vila M, Kohama I, Ochiya T.

Gan To Kagaku Ryoho. 2018 Jun;45(6):899-905. Japanese.

PMID:
30026410
7.

Regulatory role of resveratrol, a microRNA-controlling compound, in HNRNPA1 expression, which is associated with poor prognosis in breast cancer.

Otsuka K, Yamamoto Y, Ochiya T.

Oncotarget. 2018 May 15;9(37):24718-24730. doi: 10.18632/oncotarget.25339. eCollection 2018 May 15.

8.

Emerging roles of long non-coding RNA in cancer.

Sanchez Calle A, Kawamura Y, Yamamoto Y, Takeshita F, Ochiya T.

Cancer Sci. 2018 Jul;109(7):2093-2100. doi: 10.1111/cas.13642. Epub 2018 Jun 28. Review.

9.

The p53 activator overcomes resistance to ALK inhibitors by regulating p53-target selectivity in ALK-driven neuroblastomas.

Miyazaki M, Otomo R, Matsushima-Hibiya Y, Suzuki H, Nakajima A, Abe N, Tomiyama A, Ichimura K, Matsuda K, Watanabe T, Ochiya T, Nakagama H, Sakai R, Enari M.

Cell Death Discov. 2018 May 10;4:56. doi: 10.1038/s41420-018-0059-0. eCollection 2018.

10.

Differentiation Therapy by Epigenetic Reconditioning Exerts Antitumor Effects on Liver Cancer Cells.

Gailhouste L, Liew LC, Yasukawa K, Hatada I, Tanaka Y, Nakagama H, Ochiya T.

Mol Ther. 2018 Jul 5;26(7):1840-1854. doi: 10.1016/j.ymthe.2018.04.018. Epub 2018 Apr 26.

11.

Extracellular vesicles: Toward a clinical application in urological cancer treatment.

Urabe F, Kosaka N, Kimura T, Egawa S, Ochiya T.

Int J Urol. 2018 Jun;25(6):533-543. doi: 10.1111/iju.13594. Epub 2018 May 3. Review.

PMID:
29726046
12.

Imaging of angiogenesis of human umbilical vein endothelial cells by uptake of exosomes secreted from hepatocellular carcinoma cells.

Yukawa H, Suzuki K, Aoki K, Arimoto T, Yasui T, Kaji N, Ishikawa T, Ochiya T, Baba Y.

Sci Rep. 2018 Apr 30;8(1):6765. doi: 10.1038/s41598-018-24563-0.

13.

Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells.

Gailhouste L, Liew LC, Hatada I, Nakagama H, Ochiya T.

Cell Death Dis. 2018 May 1;9(5):468. doi: 10.1038/s41419-018-0487-z.

14.

Epigenetic Reprogramming of Human Hepatoma Cells: A Low-Cost Option for Drug Metabolism Assessment.

Gailhouste L, Liew LC, Yasukawa K, Hagiwara K, Iwazaki N, Yamada Y, Hatada I, Ochiya T.

Cell Mol Gastroenterol Hepatol. 2017 Nov 22;5(3):454-457.e1. doi: 10.1016/j.jcmgh.2017.11.006. eCollection 2018 Mar. No abstract available.

15.
16.

CD44 exerts a functional role during EMT induction in cisplatin-resistant head and neck cancer cells.

Miyazaki H, Takahashi RU, Prieto-Vila M, Kawamura Y, Kondo S, Shirota T, Ochiya T.

Oncotarget. 2018 Jan 13;9(11):10029-10041. doi: 10.18632/oncotarget.24252. eCollection 2018 Feb 9.

17.

Biocompatibility of highly purified bovine milk-derived extracellular vesicles.

Somiya M, Yoshioka Y, Ochiya T.

J Extracell Vesicles. 2018 Feb 21;7(1):1440132. doi: 10.1080/20013078.2018.1440132. eCollection 2018.

18.

Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A.

Hashimoto K, Ochi H, Sunamura S, Kosaka N, Mabuchi Y, Fukuda T, Yao K, Kanda H, Ae K, Okawa A, Akazawa C, Ochiya T, Futakuchi M, Takeda S, Sato S.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2204-2209. doi: 10.1073/pnas.1717363115. Epub 2018 Feb 12.

19.

Unveiling massive numbers of cancer-related urinary-microRNA candidates via nanowires.

Yasui T, Yanagida T, Ito S, Konakade Y, Takeshita D, Naganawa T, Nagashima K, Shimada T, Kaji N, Nakamura Y, Thiodorus IA, He Y, Rahong S, Kanai M, Yukawa H, Ochiya T, Kawai T, Baba Y.

Sci Adv. 2017 Dec 15;3(12):e1701133. doi: 10.1126/sciadv.1701133. eCollection 2017 Dec.

20.

[The biological role of exosomes in bone remodeling and bone diseases.]

Urabe F, Yoshioka Y, Ochiya T.

Clin Calcium. 2018;28(1):122-127. doi: CliCa1801122127. Japanese.

PMID:
29279437
21.

Epithelial stem cell culture: modeling human disease and applications for regenerative medicine.

Yamamoto Y, Ochiya T.

Inflamm Regen. 2017 Feb 6;37:3. doi: 10.1186/s41232-017-0034-9. eCollection 2017. Review.

22.

The small vesicular culprits: the investigation of extracellular vesicles as new targets for cancer treatment.

Urabe F, Kosaka N, Yoshioka Y, Egawa S, Ochiya T.

Clin Transl Med. 2017 Dec 13;6(1):45. doi: 10.1186/s40169-017-0176-z. Review.

23.

The Sox2 promoter-driven CD63-GFP transgenic rat model allows tracking of neural stem cell-derived extracellular vesicles.

Yoshimura A, Adachi N, Matsuno H, Kawamata M, Yoshioka Y, Kikuchi H, Odaka H, Numakawa T, Kunugi H, Ochiya T, Tamai Y.

Dis Model Mech. 2018 Jan 30;11(1). pii: dmm028779. doi: 10.1242/dmm.028779.

24.

Drug Resistance Driven by Cancer Stem Cells and Their Niche.

Prieto-Vila M, Takahashi RU, Usuba W, Kohama I, Ochiya T.

Int J Mol Sci. 2017 Dec 1;18(12). pii: E2574. doi: 10.3390/ijms18122574. Review.

25.

Extracellular vesicle-encapsulated microRNA-761 enhances pazopanib resistance in synovial sarcoma.

Shiozawa K, Shuting J, Yoshioka Y, Ochiya T, Kondo T.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1322-1327. doi: 10.1016/j.bbrc.2017.11.164. Epub 2017 Nov 27.

PMID:
29191657
26.

A combination of circulating miRNAs for the early detection of ovarian cancer.

Yokoi A, Yoshioka Y, Hirakawa A, Yamamoto Y, Ishikawa M, Ikeda SI, Kato T, Niimi K, Kajiyama H, Kikkawa F, Ochiya T.

Oncotarget. 2017 Sep 6;8(52):89811-89823. doi: 10.18632/oncotarget.20688. eCollection 2017 Oct 27.

27.

Emerging role of extracellular vesicles as a senescence-associated secretory phenotype: Insights into the pathophysiology of lung diseases.

Kadota T, Fujita Y, Yoshioka Y, Araya J, Kuwano K, Ochiya T.

Mol Aspects Med. 2018 Apr;60:92-103. doi: 10.1016/j.mam.2017.11.005. Epub 2017 Nov 20. Review.

28.

A tissue microRNA signature that predicts the prognosis of breast cancer in young women.

Hironaka-Mitsuhashi A, Matsuzaki J, Takahashi RU, Yoshida M, Nezu Y, Yamamoto Y, Shiino S, Kinoshita T, Ushijima T, Hiraoka N, Shimizu C, Tamura K, Ochiya T.

PLoS One. 2017 Nov 15;12(11):e0187638. doi: 10.1371/journal.pone.0187638. eCollection 2017.

29.

Circulating MicroRNA-92b-3p as a Novel Biomarker for Monitoring of Synovial Sarcoma.

Uotani K, Fujiwara T, Yoshida A, Iwata S, Morita T, Kiyono M, Yokoo S, Kunisada T, Takeda K, Hasei J, Numoto K, Nezu Y, Yonemoto T, Ishii T, Kawai A, Ochiya T, Ozaki T.

Sci Rep. 2017 Nov 7;7(1):14634. doi: 10.1038/s41598-017-12660-5.

30.

Extracellular Vesicles: New Players in Lung Immunity.

Fujita Y, Kadota T, Araya J, Ochiya T, Kuwano K.

Am J Respir Cell Mol Biol. 2018 May;58(5):560-565. doi: 10.1165/rcmb.2017-0293TR.

PMID:
29115853
31.

Circulating exosomal microRNA-203 is associated with metastasis possibly via inducing tumor-associated macrophages in colorectal cancer.

Takano Y, Masuda T, Iinuma H, Yamaguchi R, Sato K, Tobo T, Hirata H, Kuroda Y, Nambara S, Hayashi N, Iguchi T, Ito S, Eguchi H, Ochiya T, Yanaga K, Miyano S, Mimori K.

Oncotarget. 2017 Aug 7;8(45):78598-78613. doi: 10.18632/oncotarget.20009. eCollection 2017 Oct 3.

32.

MicroRNA-125b expression and intrahepatic metastasis are predictors for early recurrence after hepatocellular carcinoma resection.

Shimagaki T, Yoshizumi T, Harimoto N, Yoshio S, Naito Y, Yamamoto Y, Ochiya T, Yoshida Y, Kanto T, Maehara Y.

Hepatol Res. 2018 Mar;48(4):313-321. doi: 10.1111/hepr.12990. Epub 2017 Dec 5.

PMID:
28984009
33.

Biological and clinical insights offered by chemically induced liver progenitors (CLiPs).

Katsuda T, Ochiya T.

Stem Cell Investig. 2017 Aug 21;4:68. doi: 10.21037/sci.2017.08.04. eCollection 2017. No abstract available.

34.

Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs.

Enomoto Y, Takagi R, Naito Y, Kiniwa T, Tanaka Y, Hamada-Tsutsumi S, Kawano M, Matsushita S, Ochiya T, Miyajima A.

Sci Rep. 2017 Aug 10;7(1):7780. doi: 10.1038/s41598-017-07853-x.

35.

Trophic Activity and Phenotype of Adipose Tissue-Derived Mesenchymal Stem Cells as a Background of Their Regenerative Potential.

Kocan B, Maziarz A, Tabarkiewicz J, Ochiya T, Banaś-Ząbczyk A.

Stem Cells Int. 2017;2017:1653254. doi: 10.1155/2017/1653254. Epub 2017 Jul 5. Review.

36.

Maintaining good miRNAs in the body keeps the doctor away?: Perspectives on the relationship between food-derived natural products and microRNAs in relation to exosomes/extracellular vesicles.

Otsuka K, Yamamoto Y, Matsuoka R, Ochiya T.

Mol Nutr Food Res. 2018 Jan;62(1). doi: 10.1002/mnfr.201700080. Epub 2017 Aug 15. Review.

PMID:
28594130
37.

[Multilateral Strategies Utilizing Exosomes for Cancer Therapy].

Nishida-Aoki N, Ochiya T.

Gan To Kagaku Ryoho. 2017 May;44(5):367-372. Japanese.

PMID:
28536329
38.

Clinical significance of circulating miR-25-3p as a novel diagnostic and prognostic biomarker in osteosarcoma.

Fujiwara T, Uotani K, Yoshida A, Morita T, Nezu Y, Kobayashi E, Yoshida A, Uehara T, Omori T, Sugiu K, Komatsubara T, Takeda K, Kunisada T, Kawamura M, Kawai A, Ochiya T, Ozaki T.

Oncotarget. 2017 May 16;8(20):33375-33392. doi: 10.18632/oncotarget.16498.

39.

Exocytosis-Mediated Urinary Full-Length Megalin Excretion Is Linked With the Pathogenesis of Diabetic Nephropathy.

De S, Kuwahara S, Hosojima M, Ishikawa T, Kaseda R, Sarkar P, Yoshioka Y, Kabasawa H, Iida T, Goto S, Toba K, Higuchi Y, Suzuki Y, Hara M, Kurosawa H, Narita I, Hirayama Y, Ochiya T, Saito A.

Diabetes. 2017 May;66(5):1391-1404. doi: 10.2337/db16-1031. Epub 2017 Mar 13.

40.

Transmission of HBV DNA Mediated by Ceramide-Triggered Extracellular Vesicles.

Sanada T, Hirata Y, Naito Y, Yamamoto N, Kikkawa Y, Ishida Y, Yamasaki C, Tateno C, Ochiya T, Kohara M.

Cell Mol Gastroenterol Hepatol. 2016 Oct 24;3(2):272-283. doi: 10.1016/j.jcmgh.2016.10.003. eCollection 2017 Mar.

41.

Amigo2-upregulation in Tumour Cells Facilitates Their Attachment to Liver Endothelial Cells Resulting in Liver Metastases.

Kanda Y, Osaki M, Onuma K, Sonoda A, Kobayashi M, Hamada J, Nicolson GL, Ochiya T, Okada F.

Sci Rep. 2017 Mar 8;7:43567. doi: 10.1038/srep43567.

42.

Extracellular vesicles in lung cancer-From bench to bedside.

Kadota T, Yoshioka Y, Fujita Y, Kuwano K, Ochiya T.

Semin Cell Dev Biol. 2017 Jul;67:39-47. doi: 10.1016/j.semcdb.2017.03.001. Epub 2017 Mar 4. Review.

PMID:
28267596
43.

Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer.

Yokoi A, Yoshioka Y, Yamamoto Y, Ishikawa M, Ikeda SI, Kato T, Kiyono T, Takeshita F, Kajiyama H, Kikkawa F, Ochiya T.

Nat Commun. 2017 Mar 6;8:14470. doi: 10.1038/ncomms14470.

44.

Exosomes: toward clinical application.

Kadota T, Yoshioka Y, Fujita Y, Ochiya T.

Nihon Yakurigaku Zasshi. 2017;149(3):119-122. doi: 10.1254/fpj.149.119. Review. Japanese. No abstract available.

PMID:
28260741
45.

Extracellular vesicles as trans-genomic agents: Emerging roles in disease and evolution.

Kawamura Y, Yamamoto Y, Sato TA, Ochiya T.

Cancer Sci. 2017 May;108(5):824-830. doi: 10.1111/cas.13222. Epub 2017 May 18. Review.

46.

Circulating microRNAs and extracellular vesicles as potential cancer biomarkers: a systematic review.

Matsuzaki J, Ochiya T.

Int J Clin Oncol. 2017 Jun;22(3):413-420. doi: 10.1007/s10147-017-1104-3. Epub 2017 Feb 27. Review.

PMID:
28243946
47.

The role of extracellular vesicle microRNAs in cancer biology.

Takahashi RU, Prieto-Vila M, Hironaka A, Ochiya T.

Clin Chem Lab Med. 2017 May 1;55(5):648-656. doi: 10.1515/cclm-2016-0708. Review.

48.

Chronic treatment of non-small-cell lung cancer cells with gefitinib leads to an epigenetic loss of epithelial properties associated with reductions in microRNA-155 and -200c.

Narita M, Shimura E, Nagasawa A, Aiuchi T, Suda Y, Hamada Y, Ikegami D, Iwasawa C, Arakawa K, Igarashi K, Kuzumaki N, Yoshioka Y, Ochiya T, Takeshima H, Ushijima T, Narita M.

PLoS One. 2017 Feb 22;12(2):e0172115. doi: 10.1371/journal.pone.0172115. eCollection 2017.

49.

Mesenchymal stem cell-derived extracellular vesicles: a glimmer of hope in treating Alzheimer's disease.

Liew LC, Katsuda T, Gailhouste L, Nakagama H, Ochiya T.

Int Immunol. 2017 Jan 1;29(1):11-19. doi: 10.1093/intimm/dxx002. Review.

PMID:
28184439
50.

Disruption of Circulating Extracellular Vesicles as a Novel Therapeutic Strategy against Cancer Metastasis.

Nishida-Aoki N, Tominaga N, Takeshita F, Sonoda H, Yoshioka Y, Ochiya T.

Mol Ther. 2017 Jan 4;25(1):181-191. doi: 10.1016/j.ymthe.2016.10.009. Epub 2017 Jan 4.

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