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Items: 26

1.

Minipigs as a neonatal animal model for tuberculosis vaccine efficacy testing.

Ramos L, Obregon-Henao A, Henao-Tamayo M, Bowen R, Izzo A, Lunney JK, Gonzalez-Juarrero M.

Vet Immunol Immunopathol. 2019 Sep;215:109884. doi: 10.1016/j.vetimm.2019.109884. Epub 2019 Jul 26.

PMID:
31420066
2.

2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain.

Jeon AB, Ackart DF, Li W, Jackson M, Melander RJ, Melander C, Abramovitch RB, Chicco AJ, Basaraba RJ, Obregón-Henao A.

Sci Rep. 2019 Feb 6;9(1):1513. doi: 10.1038/s41598-018-38064-7.

3.

The minipig as an animal model to study Mycobacterium tuberculosis infection and natural transmission.

Ramos L, Obregon-Henao A, Henao-Tamayo M, Bowen R, Lunney JK, Gonzalez-Juarrero M.

Tuberculosis (Edinb). 2017 Sep;106:91-98. doi: 10.1016/j.tube.2017.07.003. Epub 2017 Jul 14.

4.

2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability.

Jeon AB, Obregón-Henao A, Ackart DF, Podell BK, Belardinelli JM, Jackson M, Nguyen TV, Blackledge MS, Melander RJ, Melander C, Johnson BK, Abramovitch RB, Basaraba RJ.

PLoS One. 2017 Jul 27;12(7):e0180925. doi: 10.1371/journal.pone.0180925. eCollection 2017.

5.

Mycobacterium bovis hosted by free-living-amoebae permits their long-term persistence survival outside of host mammalian cells and remain capable of transmitting disease to mice.

Sanchez-Hidalgo A, Obregón-Henao A, Wheat WH, Jackson M, Gonzalez-Juarrero M.

Environ Microbiol. 2017 Oct;19(10):4010-4021. doi: 10.1111/1462-2920.13810. Epub 2017 Jul 11.

PMID:
28585299
6.

The Discovery of 2-Aminobenzimidazoles That Sensitize Mycobacterium smegmatis and M. tuberculosis to β-Lactam Antibiotics in a Pattern Distinct from β-Lactamase Inhibitors.

Nguyen TV, Blackledge MS, Lindsey EA, Minrovic BM, Ackart DF, Jeon AB, Obregón-Henao A, Melander RJ, Basaraba RJ, Melander C.

Angew Chem Int Ed Engl. 2017 Mar 27;56(14):3940-3944. doi: 10.1002/anie.201612006. Epub 2017 Mar 1.

7.

Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3.

Li W, Obregón-Henao A, Wallach JB, North EJ, Lee RE, Gonzalez-Juarrero M, Schnappinger D, Jackson M.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5198-207. doi: 10.1128/AAC.00826-16. Print 2016 Sep.

8.

Effect of bacillus Calmette-Guérin vaccination on CD4+Foxp3+ T cells during acquired immune response to Mycobacterium tuberculosis infection.

Henao-Tamayo MI, Obregón-Henao A, Arnett K, Shanley CA, Podell B, Orme IM, Ordway DJ.

J Leukoc Biol. 2016 Apr;99(4):605-17. doi: 10.1189/jlb.4A0614-308RR. Epub 2015 Nov 20.

9.

Susceptibility of Mycobacterium abscessus to antimycobacterial drugs in preclinical models.

Obregón-Henao A, Arnett KA, Henao-Tamayo M, Massoudi L, Creissen E, Andries K, Lenaerts AJ, Ordway DJ.

Antimicrob Agents Chemother. 2015 Nov;59(11):6904-12. doi: 10.1128/AAC.00459-15. Epub 2015 Aug 24.

10.

A new antibiotic with potent activity targets MscL.

Iscla I, Wray R, Blount P, Larkins-Ford J, Conery AL, Ausubel FM, Ramu S, Kavanagh A, Huang JX, Blaskovich MA, Cooper MA, Obregon-Henao A, Orme I, Tjandra ES, Stroeher UH, Brown MH, Macardle C, van Holst N, Ling Tong C, Slattery AD, Gibson CT, Raston CL, Boulos RA.

J Antibiot (Tokyo). 2015 Jul;68(7):453-62. doi: 10.1038/ja.2015.4. Epub 2015 Feb 4.

11.

Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion.

Schiebler M, Brown K, Hegyi K, Newton SM, Renna M, Hepburn L, Klapholz C, Coulter S, Obregón-Henao A, Henao Tamayo M, Basaraba R, Kampmann B, Henry KM, Burgon J, Renshaw SA, Fleming A, Kay RR, Anderson KE, Hawkins PT, Ordway DJ, Rubinsztein DC, Floto RA.

EMBO Mol Med. 2015 Feb;7(2):127-39. doi: 10.15252/emmm.201404137.

12.

Differential Mycobacterium bovis BCG vaccine-derived efficacy in C3Heb/FeJ and C3H/HeOuJ mice exposed to a clinical strain of Mycobacterium tuberculosis.

Henao-Tamayo M, Obregón-Henao A, Creissen E, Shanley C, Orme I, Ordway DJ.

Clin Vaccine Immunol. 2015 Jan;22(1):91-8. doi: 10.1128/CVI.00466-14. Epub 2014 Nov 12.

13.

Increased severity of tuberculosis in Guinea pigs with type 2 diabetes: a model of diabetes-tuberculosis comorbidity.

Podell BK, Ackart DF, Obregon-Henao A, Eck SP, Henao-Tamayo M, Richardson M, Orme IM, Ordway DJ, Basaraba RJ.

Am J Pathol. 2014 Apr;184(4):1104-1118. doi: 10.1016/j.ajpath.2013.12.015. Epub 2014 Jan 31.

14.

Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection.

Obregón-Henao A, Henao-Tamayo M, Orme IM, Ordway DJ.

PLoS One. 2013 Nov 1;8(11):e80669. doi: 10.1371/journal.pone.0080669. eCollection 2013.

15.

Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity.

Sun J, Singh V, Lau A, Stokes RW, Obregón-Henao A, Orme IM, Wong D, Av-Gay Y, Hmama Z.

PLoS Pathog. 2013;9(7):e1003499. doi: 10.1371/journal.ppat.1003499. Epub 2013 Jul 18.

16.

Beijing sublineages of Mycobacterium tuberculosis differ in pathogenicity in the guinea pig.

Kato-Maeda M, Shanley CA, Ackart D, Jarlsberg LG, Shang S, Obregon-Henao A, Harton M, Basaraba RJ, Henao-Tamayo M, Barrozo JC, Rose J, Kawamura LM, Coscolla M, Fofanov VY, Koshinsky H, Gagneux S, Hopewell PC, Ordway DJ, Orme IM.

Clin Vaccine Immunol. 2012 Aug;19(8):1227-37. doi: 10.1128/CVI.00250-12. Epub 2012 Jun 20.

17.

Uptake and accumulation of oxidized low-density lipoprotein during Mycobacterium tuberculosis infection in guinea pigs.

Palanisamy GS, Kirk NM, Ackart DF, Obregón-Henao A, Shanley CA, Orme IM, Basaraba RJ.

PLoS One. 2012;7(3):e34148. doi: 10.1371/journal.pone.0034148. Epub 2012 Mar 30.

18.

A mouse model of tuberculosis reinfection.

Henao-Tamayo M, Obregón-Henao A, Ordway DJ, Shang S, Duncan CG, Orme IM.

Tuberculosis (Edinb). 2012 May;92(3):211-7. doi: 10.1016/j.tube.2012.02.008. Epub 2012 Mar 17.

PMID:
22429719
19.

Stable extracellular RNA fragments of Mycobacterium tuberculosis induce early apoptosis in human monocytes via a caspase-8 dependent mechanism.

Obregón-Henao A, Duque-Correa MA, Rojas M, García LF, Brennan PJ, Ortiz BL, Belisle JT.

PLoS One. 2012;7(1):e29970. doi: 10.1371/journal.pone.0029970. Epub 2012 Jan 9.

20.

Mycobacterium bovis BCG-mediated protection against W-Beijing strains of Mycobacterium tuberculosis is diminished concomitant with the emergence of regulatory T cells.

Ordway DJ, Shang S, Henao-Tamayo M, Obregon-Henao A, Nold L, Caraway M, Shanley CA, Basaraba RJ, Duncan CG, Orme IM.

Clin Vaccine Immunol. 2011 Sep;18(9):1527-35. doi: 10.1128/CVI.05127-11. Epub 2011 Jul 27.

21.

Vaccination of guinea pigs using mce operon mutants of Mycobacterium tuberculosis.

Obregón-Henao A, Shanley C, Bianco MV, Cataldi AA, Basaraba RJ, Orme IM, Bigi F.

Vaccine. 2011 Jun 10;29(26):4302-7. doi: 10.1016/j.vaccine.2011.04.027. Epub 2011 Apr 22.

22.

Lipoarabinomannan of Mycobacterium: mannose capping by a multifunctional terminal mannosyltransferase.

Kaur D, Obregón-Henao A, Pham H, Chatterjee D, Brennan PJ, Jackson M.

Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17973-7. doi: 10.1073/pnas.0807761105. Epub 2008 Nov 12.

23.

In situ detection of antigenic glycoproteins in Taenia solium metacestodes.

Obregón-Henao A, Londoño DP, Gómez DI, Trujillo J, Teale JM, Restrepo BI.

J Parasitol. 2003 Aug;89(4):726-32.

PMID:
14533682
24.

Structural characterization of the N-linked glycans from Taenia solium metacestodes.

Haslam SM, Restrepo BI, Obregón-Henao A, Teale JM, Morris HR, Dell A.

Mol Biochem Parasitol. 2003 Jan;126(1):103-7. No abstract available.

PMID:
12554090
25.

The role of N-linked carbohydrates in the antigenicity of Taenia solium metacestode glycoproteins of 12, 16 and 18 kD.

Obregón-Henao A, Gil DL, Gómez DI, Sanzón F, Teale JM, Restrepo BI.

Mol Biochem Parasitol. 2001 May;114(2):209-15.

PMID:
11378200
26.

Characterisation of the carbohydrate components of Taenia solium metacestode glycoprotein antigens.

Restrepo BI, Obregón-Henao A, Mesa M, Gil DL, Ortiz BL, Mejía JS, Villota GE, Sanzón F, Teale JM.

Int J Parasitol. 2000 May;30(6):689-96.

PMID:
10856502

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