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Items: 20


Cross-dressed dendritic cells sustain effector T cell responses in islet and kidney allografts.

Hughes AD, Zhao D, Dai H, Abou-Daya KI, Tieu R, Rammal R, Williams AL, Landsittel DP, Shlomchik WD, Morelli AE, Oberbarnscheidt MH, Lakkis FG.

J Clin Invest. 2019 Nov 25. pii: 125773. doi: 10.1172/JCI125773. [Epub ahead of print]


Four-Dimensional Imaging of T Cells in Kidney Transplant Rejection.

Hughes AD, Lakkis FG, Oberbarnscheidt MH.

J Am Soc Nephrol. 2018 Jun;29(6):1596-1600. doi: 10.1681/ASN.2017070800. Epub 2018 Apr 13.


Donor SIRPĪ± polymorphism modulates the innate immune response to allogeneic grafts.

Dai H, Friday AJ, Abou-Daya KI, Williams AL, Mortin-Toth S, Nicotra ML, Rothstein DM, Shlomchik WD, Matozaki T, Isenberg JS, Oberbarnscheidt MH, Danska JS, Lakkis FG.

Sci Immunol. 2017 Jun 23;2(12). pii: eaam6202. doi: 10.1126/sciimmunol.aam6202.


Getting Down and Dirty: Germ-Exposed Laboratory Mice as a Model of the Adult Human Immune System.

Tieu R, Lakkis FG, Oberbarnscheidt MH.

Transplantation. 2016 Dec;100(12):2490-2491. No abstract available.


Inflammation Causes Resistance to Anti-CD20-Mediated B Cell Depletion.

Laws LH, Parker CE, Cherala G, Koguchi Y, Waisman A, Slifka MK, Oberbarnscheidt MH, Obhrai JS, Yeung MY, Riella LV.

Am J Transplant. 2016 Nov;16(11):3139-3149. doi: 10.1111/ajt.13902. Epub 2016 Jul 12.


Graft-infiltrating host dendritic cells play a key role in organ transplant rejection.

Zhuang Q, Liu Q, Divito SJ, Zeng Q, Yatim KM, Hughes AD, Rojas-Canales DM, Nakao A, Shufesky WJ, Williams AL, Humar R, Hoffman RA, Shlomchik WD, Oberbarnscheidt MH, Lakkis FG, Morelli AE.

Nat Commun. 2016 Aug 24;7:12623. doi: 10.1038/ncomms12623.


Renal dendritic cells sample blood-borne antigen and guide T-cell migration to the kidney by means of intravascular processes.

Yatim KM, Gosto M, Humar R, Williams AL, Oberbarnscheidt MH.

Kidney Int. 2016 Oct;90(4):818-27. doi: 10.1016/j.kint.2016.05.030. Epub 2016 Aug 12.


CD8+ Effector T Cell Migration to Pancreatic Islet Grafts Is Dependent on Cognate Antigen Presentation by Donor Graft Cells.

Zhang Q, Dai H, Yatim KM, Abou-Daya K, Williams AL, Oberbarnscheidt MH, Camirand G, Rudd CE, Lakkis FG.

J Immunol. 2016 Aug 15;197(4):1471-6. doi: 10.4049/jimmunol.1600832. Epub 2016 Jun 29.


Endotoxin and AKI: Macrophages Protect after Preconditioning.

Yatim KM, Oberbarnscheidt MH.

J Am Soc Nephrol. 2015 Jun;26(6):1231-2. doi: 10.1681/ASN.2014101042. Epub 2014 Nov 14. No abstract available.


Non-self recognition by monocytes initiates allograft rejection.

Oberbarnscheidt MH, Zeng Q, Li Q, Dai H, Williams AL, Shlomchik WD, Rothstein DM, Lakkis FG.

J Clin Invest. 2014 Aug;124(8):3579-89. doi: 10.1172/JCI74370. Epub 2014 Jul 1.


Innate allorecognition.

Oberbarnscheidt MH, Lakkis FG.

Immunol Rev. 2014 Mar;258(1):145-9. doi: 10.1111/imr.12153. Review.


Cognate antigen directs CD8+ T cell migration to vascularized transplants.

Walch JM, Zeng Q, Li Q, Oberbarnscheidt MH, Hoffman RA, Williams AL, Rothstein DM, Shlomchik WD, Kim JV, Camirand G, Lakkis FG.

J Clin Invest. 2013 Jun;123(6):2663-71. doi: 10.1172/JCI66722. Epub 2013 May 15.


The innate immune system in transplantation.

Oberbarnscheidt MH, Zecher D, Lakkis FG.

Semin Immunol. 2011 Aug;23(4):264-72. doi: 10.1016/j.smim.2011.06.006. Epub 2011 Jul 1. Review.


Memory T cells migrate to and reject vascularized cardiac allografts independent of the chemokine receptor CXCR3.

Oberbarnscheidt MH, Walch JM, Li Q, Williams AL, Walters JT, Hoffman RA, Demetris AJ, Gerard C, Camirand G, Lakkis FG.

Transplantation. 2011 Apr 27;91(8):827-32. doi: 10.1097/TP.0b013e31820f0856.


B cells help alloreactive T cells differentiate into memory T cells.

Ng YH, Oberbarnscheidt MH, Chandramoorthy HC, Hoffman R, Chalasani G.

Am J Transplant. 2010 Sep;10(9):1970-80. doi: 10.1111/j.1600-6143.2010.03223.x.


NK cells delay allograft rejection in lymphopenic hosts by downregulating the homeostatic proliferation of CD8+ T cells.

Zecher D, Li Q, Oberbarnscheidt MH, Demetris AJ, Shlomchik WD, Rothstein DM, Lakkis FG.

J Immunol. 2010 Jun 15;184(12):6649-57. doi: 10.4049/jimmunol.0903729. Epub 2010 May 14.


Type I interferons are not critical for skin allograft rejection or the generation of donor-specific CD8+ memory T cells.

Oberbarnscheidt MH, Obhrai JS, Williams AL, Rothstein DM, Shlomchik WD, Chalasani G, Lakkis FG.

Am J Transplant. 2010 Jan;10(1):162-7. doi: 10.1111/j.1600-6143.2009.02871.x. Epub 2009 Nov 24.


The roles of CD8 central and effector memory T-cell subsets in allograft rejection.

Oberbarnscheidt MH, Ng YH, Chalasani G.

Am J Transplant. 2008 Sep;8(9):1809-18. doi: 10.1111/j.1600-6143.2008.02335.x. Epub 2008 Jul 28.


Tertiary lymphoid tissues generate effector and memory T cells that lead to allograft rejection.

Nasr IW, Reel M, Oberbarnscheidt MH, Mounzer RH, Baddoura FK, Ruddle NH, Lakkis FG.

Am J Transplant. 2007 May;7(5):1071-9. Epub 2007 Mar 12.


Effector T cell differentiation and memory T cell maintenance outside secondary lymphoid organs.

Obhrai JS, Oberbarnscheidt MH, Hand TW, Diggs L, Chalasani G, Lakkis FG.

J Immunol. 2006 Apr 1;176(7):4051-8.

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