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Items: 1 to 50 of 175

1.

A two-stage method for automated detection of ring-like endosomes in fluorescent microscopy images.

Lin D, Lin Z, Cao J, Velmurugan R, Ward ES, Ober RJ.

PLoS One. 2019 Jun 27;14(6):e0218931. doi: 10.1371/journal.pone.0218931. eCollection 2019.

2.

Publisher Correction: Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software.

Sage D, Pham TA, Babcock H, Lukes T, Pengo T, Chao J, Velmurugan R, Herbert A, Agrawal A, Colabrese S, Wheeler A, Archetti A, Rieger B, Ober R, Hagen GM, Sibarita JB, Ries J, Henriques R, Unser M, Holden S.

Nat Methods. 2019 Jun;16(6):561. doi: 10.1038/s41592-019-0453-4.

PMID:
31097821
3.

Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis.

Challa DK, Wang X, Montoyo HP, Velmurugan R, Ober RJ, Ward ES.

MAbs. 2019 Jul;11(5):848-860. doi: 10.1080/19420862.2019.1602459. Epub 2019 Apr 30.

4.

Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software.

Sage D, Pham TA, Babcock H, Lukes T, Pengo T, Chao J, Velmurugan R, Herbert A, Agrawal A, Colabrese S, Wheeler A, Archetti A, Rieger B, Ober R, Hagen GM, Sibarita JB, Ries J, Henriques R, Unser M, Holden S.

Nat Methods. 2019 May;16(5):387-395. doi: 10.1038/s41592-019-0364-4. Epub 2019 Apr 8. Erratum in: Nat Methods. 2019 Jun;16(6):561.

5.

Engineering a HER2-specific antibody-drug conjugate to increase lysosomal delivery and therapeutic efficacy.

Kang JC, Sun W, Khare P, Karimi M, Wang X, Shen Y, Ober RJ, Ward ES.

Nat Biotechnol. 2019 May;37(5):523-526. doi: 10.1038/s41587-019-0073-7. Epub 2019 Apr 1.

6.

Resolution limit of image analysis algorithms.

Cohen EAK, Abraham AV, Ramakrishnan S, Ober RJ.

Nat Commun. 2019 Feb 15;10(1):793. doi: 10.1038/s41467-019-08689-x.

7.

Targeting FcRn to Generate Antibody-Based Therapeutics.

Ward ES, Ober RJ.

Trends Pharmacol Sci. 2018 Oct;39(10):892-904. doi: 10.1016/j.tips.2018.07.007. Epub 2018 Aug 22. Review.

8.

Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans.

Ulrichts P, Guglietta A, Dreier T, van Bragt T, Hanssens V, Hofman E, Vankerckhoven B, Verheesen P, Ongenae N, Lykhopiy V, Enriquez FJ, Cho J, Ober RJ, Ward ES, de Haard H, Leupin N.

J Clin Invest. 2018 Oct 1;128(10):4372-4386. doi: 10.1172/JCI97911. Epub 2018 Jul 24.

9.

Phagocytosis of antibody-opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages.

Velmurugan R, Ramakrishnan S, Kim M, Ober RJ, Ward ES.

Traffic. 2018 Apr;19(4):273-284. doi: 10.1111/tra.12552.

10.

Myelin oligodendrocyte glycoprotein-specific antibodies from multiple sclerosis patients exacerbate disease in a humanized mouse model.

Khare P, Challa DK, Devanaboyina SC, Velmurugan R, Hughes S, Greenberg BM, Ober RJ, Ward ES.

J Autoimmun. 2018 Jan;86:104-115. doi: 10.1016/j.jaut.2017.09.002. Epub 2017 Sep 28.

11.

Targeting Phosphatidylserine with Calcium-Dependent Protein-Drug Conjugates for the Treatment of Cancer.

Li R, Chiguru S, Li L, Kim D, Velmurugan R, Kim D, Devanaboyina SC, Tian H, Schroit A, Mason RP, Ober RJ, Ward ES.

Mol Cancer Ther. 2018 Jan;17(1):169-182. doi: 10.1158/1535-7163.MCT-17-0092. Epub 2017 Sep 22.

12.

Increased microbiome diversity at the time of infection is associated with improved growth rates of pigs after co-infection with porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2).

Ober RA, Thissen JB, Jaing CJ, Cino-Ozuna AG, Rowland RRR, Niederwerder MC.

Vet Microbiol. 2017 Sep;208:203-211. doi: 10.1016/j.vetmic.2017.06.023. Epub 2017 Aug 18.

PMID:
28888639
13.

Hepatic function of FcRn revealed: Implications for overcoming drug-mediated hepatotoxicity.

Ward ES, Ober RJ.

Hepatology. 2017 Dec;66(6):2083-2085. doi: 10.1002/hep.29476. Epub 2017 Nov 8. No abstract available.

PMID:
28833333
14.

A state space based approach to localizing single molecules from multi-emitter images.

Vahid MR, Chao J, Ward ES, Ober RJ.

Proc SPIE Int Soc Opt Eng. 2017 Jan 28;10070. pii: 100700J. doi: 10.1117/12.2253175. Epub 2017 Feb 17.

15.

State space approach to single molecule localization in fluorescence microscopy.

Vahid MR, Chao J, Kim D, Ward ES, Ober RJ.

Biomed Opt Express. 2017 Feb 6;8(3):1332-1355. doi: 10.1364/BOE.8.001332. eCollection 2017 Mar 1.

16.

Remote focusing multifocal plane microscopy for the imaging of 3D single molecule dynamics with cellular context.

Chao J, Velmurugan R, You S, Kim D, Ward ES, Ober RJ.

Proc SPIE Int Soc Opt Eng. 2017 Jan 28;10070. pii: 100700L. doi: 10.1117/12.2251218. Epub 2017 Feb 17.

17.

Engineered clearing agents for the selective depletion of antigen-specific antibodies.

Devanaboyina SC, Khare P, Challa DK, Ober RJ, Ward ES.

Nat Commun. 2017 May 31;8:15314. doi: 10.1038/ncomms15314.

18.

Automatic Endosomal Structure Detection And Localization in Fluorescence Microscopic Images.

Lin D, Lin Z, Velmurugan R, Ober RJ.

IEEE Int Symp Circuits Syst Proc. 2017 May;2017. doi: 10.1109/ISCAS.2017.8050242. Epub 2017 Sep 28.

19.

Intensity-based axial localization approaches for multifocal plane microscopy.

Velmurugan R, Chao J, Ram S, Ward ES, Ober RJ.

Opt Express. 2017 Feb 20;25(4):3394-3410. doi: 10.1364/OE.25.003394.

20.

Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption.

Swiercz R, Mo M, Khare P, Schneider Z, Ober RJ, Ward ES.

Oncotarget. 2017 Jan 10;8(2):3528-3541. doi: 10.18632/oncotarget.13869.

21.

Fisher information theory for parameter estimation in single molecule microscopy: tutorial.

Chao J, Sally Ward E, Ober RJ.

J Opt Soc Am A Opt Image Sci Vis. 2016 Jul 1;33(7):B36-57. doi: 10.1364/JOSAA.33.000B36.

22.

Antigen dynamics govern the induction of CD4(+) T cell tolerance during autoimmunity.

Challa DK, Mi W, Lo ST, Ober RJ, Ward ES.

J Autoimmun. 2016 Aug;72:84-94. doi: 10.1016/j.jaut.2016.05.007. Epub 2016 May 25.

23.

Macrophage-Mediated Trogocytosis Leads to Death of Antibody-Opsonized Tumor Cells.

Velmurugan R, Challa DK, Ram S, Ober RJ, Ward ES.

Mol Cancer Ther. 2016 Aug;15(8):1879-89. doi: 10.1158/1535-7163.MCT-15-0335. Epub 2016 May 25.

24.

Investigating the usage of point spread functions in point source and microsphere localization.

Chao J, Ram S, Ward ES, Ober RJ.

Proc SPIE Int Soc Opt Eng. 2016 Feb 13;9713. pii: 97131M. Epub 2016 Mar 9.

25.

Cramér-Rao Lower Bound for Point Based Image Registration With Heteroscedastic Error Model for Application in Single Molecule Microscopy.

Cohen EA, Kim D, Ober RJ.

IEEE Trans Med Imaging. 2015 Dec;34(12):2632-44. doi: 10.1109/TMI.2015.2451513.

26.

New results on the single molecule localization problem in two and three dimensions.

Tahmasb A, Ward ES, Ober RJ.

Proc SPIE Int Soc Opt Eng. 2015 Aug 9;9554. pii: 955402.

27.

Limit of the Accuracy of Parameter Estimation for Two Molecules Moving in Close Proximity.

Lin Z, Wong Y, Ober RJ.

IEEE Int Symp Circuits Syst Proc. 2015 May;2015:441-444.

28.

Commentary: "There's been a Flaw in Our Thinking".

Ward ES, Ober RJ.

Front Immunol. 2015 Jul 16;6:351. doi: 10.3389/fimmu.2015.00351. eCollection 2015. No abstract available.

29.

Fluorescent Microspheres as Point Sources: A Localization Study.

Chao J, Lee T, Ward ES, Ober RJ.

PLoS One. 2015 Jul 28;10(7):e0134112. doi: 10.1371/journal.pone.0134112. eCollection 2015.

30.

Investigation of the numerics of point spread function integration in single molecule localization.

Chao J, Ram S, Lee T, Ward ES, Ober RJ.

Opt Express. 2015 Jun 29;23(13):16866-83. doi: 10.1364/OE.23.016866.

31.

Quantitative Aspects of Single Molecule Microscopy.

Ober RJ, Tahmasbi A, Ram S, Lin Z, Ward ES.

IEEE Signal Process Mag. 2015 Jan;32(1):58-69.

32.

An information-theoretic approach to designing the plane spacing for multifocal plane microscopy.

Tahmasbi A, Ram S, Chao J, Abraham AV, Ward ES, Ober RJ.

Proc SPIE Int Soc Opt Eng. 2015 Feb 7;9330. pii: 933011.

33.

Determination of localization accuracy based on experimentally acquired image sets: applications to single molecule microscopy.

Tahmasbi A, Ward ES, Ober RJ.

Opt Express. 2015 Mar 23;23(6):7630-52. doi: 10.1364/OE.23.007630.

34.

Targeting FcRn for the modulation of antibody dynamics.

Ward ES, Devanaboyina SC, Ober RJ.

Mol Immunol. 2015 Oct;67(2 Pt A):131-41. doi: 10.1016/j.molimm.2015.02.007. Epub 2015 Mar 9. Review.

35.

The level of HER2 expression is a predictor of antibody-HER2 trafficking behavior in cancer cells.

Ram S, Kim D, Ober RJ, Ward ES.

MAbs. 2014;6(5):1211-9. doi: 10.4161/mabs.29865.

36.

Antibody targeting of HER2/HER3 signaling overcomes heregulin-induced resistance to PI3K inhibition in prostate cancer.

Poovassery JS, Kang JC, Kim D, Ober RJ, Ward ES.

Int J Cancer. 2015 Jul 15;137(2):267-77. doi: 10.1002/ijc.29378. Epub 2014 Dec 19.

37.

Effect of time discretization of the imaging process on the accuracy of trajectory estimation in fluorescence microscopy.

Wong Y, Chao J, Lin Z, Ober RJ.

Opt Express. 2014 Aug 25;22(17):20396-420. doi: 10.1364/OE.22.020396.

38.

FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions.

Challa DK, Velmurugan R, Ober RJ, Sally Ward E.

Curr Top Microbiol Immunol. 2014;382:249-72. doi: 10.1007/978-3-319-07911-0_12. Review.

PMID:
25116104
39.

Designing the focal plane spacing for multifocal plane microscopy.

Tahmasbi A, Ram S, Chao J, Abraham AV, Tang FW, Ward ES, Ober RJ.

Opt Express. 2014 Jul 14;22(14):16706-21. doi: 10.1364/OE.22.016706.

41.

Use of Fc-Engineered Antibodies as Clearing Agents to Increase Contrast During PET.

Swiercz R, Chiguru S, Tahmasbi A, Ramezani SM, Hao G, Challa DK, Lewis MA, Kulkarni PV, Sun X, Ober RJ, Mason RP, Ward ES.

J Nucl Med. 2014 Jul;55(7):1204-7. doi: 10.2967/jnumed.113.136481. Epub 2014 May 27.

42.

Analysis of Point Based Image Registration Errors With Applications in Single Molecule Microscopy.

Cohen EA, Ober RJ.

IEEE Trans Signal Process. 2013 Dec 15;61(24):6291-6306.

43.

Targeting FcRn for therapy: from live cell imaging to in vivo studies in mice.

Ward ES, Velmurugan R, Ober RJ.

Immunol Lett. 2014 Aug;160(2):158-62. doi: 10.1016/j.imlet.2014.02.008. Epub 2014 Feb 23. Review.

44.

The effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics.

Devanaboyina SC, Lynch SM, Ober RJ, Ram S, Kim D, Puig-Canto A, Breen S, Kasturirangan S, Fowler S, Peng L, Zhong H, Jermutus L, Wu H, Webster C, Ward ES, Gao C.

MAbs. 2013 Nov-Dec;5(6):851-9. doi: 10.4161/mabs.26389.

45.

Engineering multivalent antibodies to target heregulin-induced HER3 signaling in breast cancer cells.

Kang JC, Poovassery JS, Bansal P, You S, Manjarres IM, Ober RJ, Ward ES.

MAbs. 2014 Mar-Apr;6(2):340-53. doi: 10.4161/mabs.27658. Epub 2013 Dec 26.

46.

3D single molecule tracking and superresolution microscopy using multifocal plane microscopy.

Ram S, Ward ES, Ober RJ.

Proc IEEE Int Symp Biomed Imaging. 2012 Dec 31;2012:914-915.

47.

Autoantibody depletion ameliorates disease in murine experimental autoimmune encephalomyelitis.

Challa DK, Bussmeyer U, Khan T, Montoyo HP, Bansal P, Ober RJ, Ward ES.

MAbs. 2013 Sep-Oct;5(5):655-9. doi: 10.4161/mabs.25439. Epub 2013 Jun 19.

48.

The encephalitogenic, human myelin oligodendrocyte glycoprotein-induced antibody repertoire is directed toward multiple epitopes in C57BL/6-immunized mice.

Bansal P, Khan T, Bussmeyer U, Challa DK, Swiercz R, Velmurugan R, Ober RJ, Ward ES.

J Immunol. 2013 Aug 1;191(3):1091-101. doi: 10.4049/jimmunol.1300019. Epub 2013 Jul 1.

49.
50.

Ultrahigh accuracy imaging modality for super-localization microscopy.

Chao J, Ram S, Ward ES, Ober RJ.

Nat Methods. 2013 Apr;10(4):335-8. doi: 10.1038/nmeth.2396. Epub 2013 Mar 3.

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