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Items: 20


A Predictor of Pathological Complete Response to Neoadjuvant Chemotherapy Stratifies Triple Negative Breast Cancer Patients with High Risk of Recurrence.

Fournier MV, Goodwin EC, Chen J, Obenauer JC, Tannenbaum SH, Brufsky AM.

Sci Rep. 2019 Oct 16;9(1):14863. doi: 10.1038/s41598-019-51335-1.


A Novel Panel of 80 RNA Biomarkers with Differential Expression in Multiple Human Solid Tumors against Healthy Blood Samples.

Delmonico L, Obenauer JC, Qureshi F, Alves G, Costa MASM, Martin KJ, Fournier MV.

Int J Mol Sci. 2019 Oct 2;20(19). pii: E4894. doi: 10.3390/ijms20194894.


Expression Concordance of 325 Novel RNA Biomarkers between Data Generated by NanoString nCounter and Affymetrix GeneChip.

Delmonico L, Attiya S, Chen JW, Obenauer JC, Goodwin EC, Fournier MV.

Dis Markers. 2019 May 14;2019:1940347. doi: 10.1155/2019/1940347. eCollection 2019.


The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics.

Huang R, Grishagin I, Wang Y, Zhao T, Greene J, Obenauer JC, Ngan D, Nguyen DT, Guha R, Jadhav A, Southall N, Simeonov A, Austin CP.

Front Pharmacol. 2019 Apr 26;10:445. doi: 10.3389/fphar.2019.00445. eCollection 2019.


Recurrently affected genes in juvenile myelomonocytic leukaemia.

Obenauer JC, Kavelaars FG, Sanders MA, de Vries ACH, de Haas V, Beverloo HB, De Moerloose B, Lammens T, Dworzak M, Hoogenboezem RM, Valk PJM, Touw IP, van den Heuvel-Eibrink MM.

Br J Haematol. 2018 Jul;182(1):135-138. doi: 10.1111/bjh.14737. Epub 2017 May 9. No abstract available.


Lack of splice factor and cohesin complex mutations in pediatric myelodysplastic syndrome.

Obenauer JC, Kavelaars FG, Sanders MA, Hoogenboezem RM, de Vries AC, van Strien PM, de Haas V, Locatelli F, Hasle H, Valk PJ, Touw IP, van den Heuvel-Eibrink MM.

Haematologica. 2016 Dec;101(12):e479-e481. Epub 2016 Sep 1. No abstract available.


Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression.

Kasper LH, Qu C, Obenauer JC, McGoldrick DJ, Brindle PK.

Nucleic Acids Res. 2014 Oct;42(18):11363-82. doi: 10.1093/nar/gku827. Epub 2014 Sep 23.


The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG.

Nature. 2012 Jan 11;481(7380):157-63. doi: 10.1038/nature10725.


CREST maps somatic structural variation in cancer genomes with base-pair resolution.

Wang J, Mullighan CG, Easton J, Roberts S, Heatley SL, Ma J, Rusch MC, Chen K, Harris CC, Ding L, Holmfeldt L, Payne-Turner D, Fan X, Wei L, Zhao D, Obenauer JC, Naeve C, Mardis ER, Wilson RK, Downing JR, Zhang J.

Nat Methods. 2011 Jun 12;8(8):652-4. doi: 10.1038/nmeth.1628.


T cell receptor CDR3 sequence but not recognition characteristics distinguish autoreactive effector and Foxp3(+) regulatory T cells.

Liu X, Nguyen P, Liu W, Cheng C, Steeves M, Obenauer JC, Ma J, Geiger TL.

Immunity. 2009 Dec 18;31(6):909-20. doi: 10.1016/j.immuni.2009.09.023. Epub 2009 Dec 10.


Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome.

Galea CA, High AA, Obenauer JC, Mishra A, Park CG, Punta M, Schlessinger A, Ma J, Rost B, Slaughter CA, Kriwacki RW.

J Proteome Res. 2009 Jan;8(1):211-26. doi: 10.1021/pr800308v.


Globin lentiviral vector insertions can perturb the expression of endogenous genes in beta-thalassemic hematopoietic cells.

Hargrove PW, Kepes S, Hanawa H, Obenauer JC, Pei D, Cheng C, Gray JT, Neale G, Persons DA.

Mol Ther. 2008 Mar;16(3):525-33. doi: 10.1038/ Epub 2008 Jan 15.


Influenza in migratory birds and evidence of limited intercontinental virus exchange.

Krauss S, Obert CA, Franks J, Walker D, Jones K, Seiler P, Niles L, Pryor SP, Obenauer JC, Naeve CW, Widjaja L, Webby RJ, Webster RG.

PLoS Pathog. 2007 Nov;3(11):e167.


Persistent host markers in pandemic and H5N1 influenza viruses.

Finkelstein DB, Mukatira S, Mehta PK, Obenauer JC, Su X, Webster RG, Naeve CW.

J Virol. 2007 Oct;81(19):10292-9. Epub 2007 Jul 25.


Expression of SMARCB1 modulates steroid sensitivity in human lymphoblastoid cells: identification of a promoter SNP that alters PARP1 binding and SMARCB1 expression.

Pottier N, Cheok MH, Yang W, Assem M, Tracey L, Obenauer JC, Panetta JC, Relling MV, Evans WE.

Hum Mol Genet. 2007 Oct 1;16(19):2261-71. Epub 2007 Jul 5.


Proteomic studies of the intrinsically unstructured mammalian proteome.

Galea CA, Pagala VR, Obenauer JC, Park CG, Slaughter CA, Kriwacki RW.

J Proteome Res. 2006 Oct;5(10):2839-48.


Large-scale sequence analysis of avian influenza isolates.

Obenauer JC, Denson J, Mehta PK, Su X, Mukatira S, Finkelstein DB, Xu X, Wang J, Ma J, Fan Y, Rakestraw KM, Webster RG, Hoffmann E, Krauss S, Zheng J, Zhang Z, Naeve CW.

Science. 2006 Mar 17;311(5767):1576-80. Epub 2006 Jan 26.


Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

Wadkins RM, Hyatt JL, Wei X, Yoon KJ, Wierdl M, Edwards CC, Morton CL, Obenauer JC, Damodaran K, Beroza P, Danks MK, Potter PM.

J Med Chem. 2005 Apr 21;48(8):2906-15.


Computational prediction of protein-protein interactions.

Obenauer JC, Yaffe MB.

Methods Mol Biol. 2004;261:445-68. Review.


Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs.

Obenauer JC, Cantley LC, Yaffe MB.

Nucleic Acids Res. 2003 Jul 1;31(13):3635-41.

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