Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 49

1.

Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure.

Cruz-Topete D, Oakley RH, Carroll NG, He B, Myers PH, Xu X, Watts MN, Trosclair K, Glasscock E, Dominic P, Cidlowski JA.

J Am Heart Assoc. 2019 Aug 6;8(15):e011012. doi: 10.1161/JAHA.118.011012. Epub 2019 Jul 17.

2.

β-Arrestin-1 inhibits glucocorticoid receptor turnover and alters glucocorticoid signaling.

Petrillo MG, Oakley RH, Cidlowski JA.

J Biol Chem. 2019 Jul 19;294(29):11225-11239. doi: 10.1074/jbc.RA118.007150. Epub 2019 Jun 5.

PMID:
31167788
3.

Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice.

Oakley RH, Cruz-Topete D, He B, Foley JF, Myers PH, Xu X, Gomez-Sanchez CE, Chambon P, Willis MS, Cidlowski JA.

Sci Signal. 2019 Apr 16;12(577). pii: eaau9685. doi: 10.1126/scisignal.aau9685.

PMID:
30992401
4.

Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice.

Oakley RH, Campen MJ, Paffett ML, Chen X, Wang Z, Parry TL, Hillhouse C, Cidlowski JA, Willis MS.

BMC Med Genet. 2018 Sep 21;19(1):175. doi: 10.1186/s12881-018-0670-1.

5.

Glucocorticoid receptor isoform-specific regulation of development, circadian rhythm, and inflammation in mice.

Oakley RH, Ramamoorthy S, Foley JF, Busada JT, Lu NZ, Cidlowski JA.

FASEB J. 2018 Oct;32(10):5258-5271. doi: 10.1096/fj.201701153R. Epub 2018 Apr 19.

PMID:
29672221
6.

Neonatal Genistein Exposure and Glucocorticoid Signaling in the Adult Mouse Uterus.

Whirledge SD, Kisanga EP, Oakley RH, Cidlowski JA.

Environ Health Perspect. 2018 Apr 5;126(4):047002. doi: 10.1289/EHP1575.

7.
8.

MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1.

Venturutti L, Cordo Russo RI, Rivas MA, Mercogliano MF, Izzo F, Oakley RH, Pereyra MG, De Martino M, Proietti CJ, Yankilevich P, Roa JC, Guzmán P, Cortese E, Allemand DH, Huang TH, Charreau EH, Cidlowski JA, Schillaci R, Elizalde PV.

Oncogene. 2016 Dec 1;35(48):6189-6202. doi: 10.1038/onc.2016.151. Epub 2016 May 9.

9.

Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver.

He B, Cruz-Topete D, Oakley RH, Xiao X, Cidlowski JA.

Mol Cell Biol. 2015 Dec 28;36(5):714-30. doi: 10.1128/MCB.00908-15.

10.

Uterine glucocorticoid receptors are critical for fertility in mice through control of embryo implantation and decidualization.

Whirledge SD, Oakley RH, Myers PH, Lydon JP, DeMayo F, Cidlowski JA.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15166-71. doi: 10.1073/pnas.1508056112. Epub 2015 Nov 23.

11.

Glucocorticoid signaling in the heart: A cardiomyocyte perspective.

Oakley RH, Cidlowski JA.

J Steroid Biochem Mol Biol. 2015 Sep;153:27-34. doi: 10.1016/j.jsbmb.2015.03.009. Epub 2015 Mar 21. Review.

12.

HES1 is a master regulator of glucocorticoid receptor-dependent gene expression.

Revollo JR, Oakley RH, Lu NZ, Kadmiel M, Gandhavadi M, Cidlowski JA.

Sci Signal. 2013 Dec 3;6(304):ra103. doi: 10.1126/scisignal.2004389.

13.

The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease.

Oakley RH, Cidlowski JA.

J Allergy Clin Immunol. 2013 Nov;132(5):1033-44. doi: 10.1016/j.jaci.2013.09.007. Epub 2013 Sep 29. Review.

14.

Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease.

Oakley RH, Ren R, Cruz-Topete D, Bird GS, Myers PH, Boyle MC, Schneider MD, Willis MS, Cidlowski JA.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17035-40. doi: 10.1073/pnas.1302546110. Epub 2013 Sep 30.

15.

Desensitization of human CRF2(a) receptor signaling governed by agonist potency and βarrestin2 recruitment.

Hauger RL, Olivares-Reyes JA, Braun S, Hernandez-Aranda J, Hudson CC, Gutknecht E, Dautzenberg FM, Oakley RH.

Regul Pept. 2013 Sep 10;186:62-76. doi: 10.1016/j.regpep.2013.06.009. Epub 2013 Jun 29.

16.

Glucocorticoids regulate arrestin gene expression and redirect the signaling profile of G protein-coupled receptors.

Oakley RH, Revollo J, Cidlowski JA.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17591-6. doi: 10.1073/pnas.1209411109. Epub 2012 Oct 8.

17.

Dual role for glucocorticoids in cardiomyocyte hypertrophy and apoptosis.

Ren R, Oakley RH, Cruz-Topete D, Cidlowski JA.

Endocrinology. 2012 Nov;153(11):5346-60. doi: 10.1210/en.2012-1563. Epub 2012 Sep 18.

18.

Molecular and cell signaling targets for PTSD pathophysiology and pharmacotherapy.

Hauger RL, Olivares-Reyes JA, Dautzenberg FM, Lohr JB, Braun S, Oakley RH.

Neuropharmacology. 2012 Feb;62(2):705-14. doi: 10.1016/j.neuropharm.2011.11.007. Epub 2011 Nov 25. Review.

19.

Glucocorticoid receptor alpha isoform-selective regulation of antiapoptotic genes in osteosarcoma cells: a new mechanism for glucocorticoid resistance.

Gross KL, Oakley RH, Scoltock AB, Jewell CM, Cidlowski JA.

Mol Endocrinol. 2011 Jul;25(7):1087-99. doi: 10.1210/me.2010-0051. Epub 2011 Apr 28.

20.

Cellular processing of the glucocorticoid receptor gene and protein: new mechanisms for generating tissue-specific actions of glucocorticoids.

Oakley RH, Cidlowski JA.

J Biol Chem. 2011 Feb 4;286(5):3177-84. doi: 10.1074/jbc.R110.179325. Epub 2010 Dec 13. Review.

21.

Role of CRF receptor signaling in stress vulnerability, anxiety, and depression.

Hauger RL, Risbrough V, Oakley RH, Olivares-Reyes JA, Dautzenberg FM.

Ann N Y Acad Sci. 2009 Oct;1179:120-43. doi: 10.1111/j.1749-6632.2009.05011.x. Review.

23.

Carboxyl-terminal and intracellular loop sites for CRF1 receptor phosphorylation and beta-arrestin-2 recruitment: a mechanism regulating stress and anxiety responses.

Oakley RH, Olivares-Reyes JA, Hudson CC, Flores-Vega F, Dautzenberg FM, Hauger RL.

Am J Physiol Regul Integr Comp Physiol. 2007 Jul;293(1):R209-22. Epub 2007 Mar 15.

24.

High-content screening of known G protein-coupled receptors by arrestin translocation.

Hudson CC, Oakley RH, Sjaastad MD, Loomis CR.

Methods Enzymol. 2006;414:63-78.

PMID:
17110187
25.
26.

A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors.

Marion S, Oakley RH, Kim KM, Caron MG, Barak LS.

J Biol Chem. 2006 Feb 3;281(5):2932-8. Epub 2005 Nov 30.

27.

Quantitative cell-based high-content screening for vasopressin receptor agonists using transfluor technology.

Ghosh RN, DeBiasio R, Hudson CC, Ramer ER, Cowan CL, Oakley RH.

J Biomol Screen. 2005 Aug;10(5):476-84.

PMID:
16093557
28.
29.

Beta-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor desensitization.

Pi M, Oakley RH, Gesty-Palmer D, Cruickshank RD, Spurney RF, Luttrell LM, Quarles LD.

Mol Endocrinol. 2005 Apr;19(4):1078-87. Epub 2005 Jan 6.

PMID:
15637145
30.
31.

The cellular distribution of fluorescently labeled arrestins provides a robust, sensitive, and universal assay for screening G protein-coupled receptors.

Oakley RH, Hudson CC, Cruickshank RD, Meyers DM, Payne RE Jr, Rhem SM, Loomis CR.

Assay Drug Dev Technol. 2002 Nov;1(1 Pt 1):21-30.

PMID:
15090153
32.

The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.

Tohgo A, Choy EW, Gesty-Palmer D, Pierce KL, Laporte S, Oakley RH, Caron MG, Lefkowitz RJ, Luttrell LM.

J Biol Chem. 2003 Feb 21;278(8):6258-67. Epub 2002 Dec 6.

33.

Signal transduction. Bringing channels closer to the action!

Laporte SA, Oakley RH, Caron MG.

Science. 2001 Jul 6;293(5527):62-3. No abstract available.

PMID:
11441172
35.

Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*.

Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG.

J Biol Chem. 2001 Jun 1;276(22):19452-60. Epub 2001 Mar 9.

36.
37.
38.
39.
40.

Immunocytochemical analysis of the glucocorticoid receptor alpha isoform (GRalpha) using GRalpha-specific antibody.

Oakley RH, Webster JC, Jewell CM, Sar M, Cidlowski JA.

Steroids. 1999 Oct;64(10):742-51.

PMID:
10498033
41.

The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action.

Oakley RH, Jewell CM, Yudt MR, Bofetiado DM, Cidlowski JA.

J Biol Chem. 1999 Sep 24;274(39):27857-66.

42.

The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis.

Laporte SA, Oakley RH, Zhang J, Holt JA, Ferguson SS, Caron MG, Barak LS.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3712-7.

43.

Expression and subcellular distribution of the beta-isoform of the human glucocorticoid receptor.

Oakley RH, Webster JC, Sar M, Parker CR Jr, Cidlowski JA.

Endocrinology. 1997 Nov;138(11):5028-38.

PMID:
9348235
44.
46.

Homologous down regulation of the glucocorticoid receptor: the molecular machinery.

Oakley RH, Cidlowski JA.

Crit Rev Eukaryot Gene Expr. 1993;3(2):63-88. Review.

PMID:
8324294
47.

Multiple benign mesenchymomata of the chest wall.

Oakley RH, Carty H, Cudmore RE.

Pediatr Radiol. 1985;15(1):58-60.

PMID:
3969297
48.

Review of spondylolisthesis and spondylolysis in paediatric practice.

Oakley RH, Carty H.

Br J Radiol. 1984 Oct;57(682):877-85.

PMID:
6237709
49.

Analysis of the chest radiograph in Legionnaires' disease.

Evans AF, Oakley RH, Whitehouse GH.

Clin Radiol. 1981 Jul;32(4):361-5.

PMID:
7249511

Supplemental Content

Loading ...
Support Center