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Items: 1 to 50 of 66

1.

Severe white matter astrocytopathy in CADASIL.

Hase Y, Chen A, Bates LL, Craggs LJL, Yamamoto Y, Gemmell E, Oakley AE, Korolchuk VI, Kalaria RN.

Brain Pathol. 2018 Nov;28(6):832-843. doi: 10.1111/bpa.12621.

2.

Multiplex analyte assays to characterize different dementias: brain inflammatory cytokines in poststroke and other dementias.

Chen A, Oakley AE, Monteiro M, Tuomela K, Allan LM, Mukaetova-Ladinska EB, O'Brien JT, Kalaria RN.

Neurobiol Aging. 2016 Feb;38:56-67. doi: 10.1016/j.neurobiolaging.2015.10.021. Epub 2015 Oct 30.

3.

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia.

Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung'u MN, Foster V, Craggs LJ, Washida K, Okamoto Y, Thomas AJ, Polvikoski TM, Allan LM, Oakley AE, O'Brien JT, Horsburgh K, Ihara M, Kalaria RN.

Brain. 2016 Jan;139(Pt 1):242-58. doi: 10.1093/brain/awv328. Epub 2015 Dec 14.

4.

κ Agonists as a novel therapy for menopausal hot flashes.

Oakley AE, Steiner RA, Chavkin C, Clifton DK, Ferrara LK, Reed SD.

Menopause. 2015 Dec;22(12):1328-34. doi: 10.1097/GME.0000000000000476.

5.

Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases.

Craggs L, Taylor J, Slade JY, Chen A, Hagel C, Kuhlenbaeumer G, Borjesson-Hanson A, Viitanen M, Kalimo H, Deramecourt V, Oakley AE, Kalaria RN.

Neuropathol Appl Neurobiol. 2016 Feb;42(2):194-209. doi: 10.1111/nan.12248. Epub 2015 Jun 17.

6.

Tau proteins in the temporal and frontal cortices in patients with vascular dementia.

Mukaetova-Ladinska EB, Abdel-All Z, Mugica ES, Li M, Craggs LJ, Oakley AE, Honer WG, Kalaria RN.

J Neuropathol Exp Neurol. 2015 Feb;74(2):148-57. doi: 10.1097/NEN.0000000000000157.

PMID:
25575131
7.

Immunolocalization of platelet-derived growth factor receptor-β (PDGFR-β) and pericytes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Craggs LJ, Fenwick R, Oakley AE, Ihara M, Kalaria RN.

Neuropathol Appl Neurobiol. 2015 Jun;41(4):557-70. doi: 10.1111/nan.12188. Epub 2015 Apr 23.

8.

Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias.

Foster V, Oakley AE, Slade JY, Hall R, Polvikoski TM, Burke M, Thomas AJ, Khundakar A, Allan LM, Kalaria RN.

Brain. 2014 Sep;137(Pt 9):2509-21. doi: 10.1093/brain/awu172. Epub 2014 Jun 28.

PMID:
24974383
9.

Neuron volumes in hippocampal subfields in delayed poststroke and aging-related dementias.

Gemmell E, Tam E, Allan L, Hall R, Khundakar A, Oakley AE, Thomas A, Deramecourt V, Kalaria RN.

J Neuropathol Exp Neurol. 2014 Apr;73(4):305-11. doi: 10.1097/NEN.0000000000000054.

PMID:
24607963
10.

Morphometry of the hippocampal microvasculature in post-stroke and age-related dementias.

Burke MJ, Nelson L, Slade JY, Oakley AE, Khundakar AA, Kalaria RN.

Neuropathol Appl Neurobiol. 2014 Apr;40(3):284-95. doi: 10.1111/nan.12085.

11.

White matter pathology and disconnection in the frontal lobe in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Craggs LJ, Yamamoto Y, Ihara M, Fenwick R, Burke M, Oakley AE, Roeber S, Duering M, Kretzschmar H, Kalaria RN.

Neuropathol Appl Neurobiol. 2014 Aug;40(5):591-602. doi: 10.1111/nan.12073.

12.

Redundancy in Kiss1 expression safeguards reproduction in the mouse.

Popa SM, Moriyama RM, Caligioni CS, Yang JJ, Cho CM, Concepcion TL, Oakley AE, Lee IH, Sanz E, Amieux PS, Caraty A, Palmiter RD, Navarro VM, Chan YM, Seminara SB, Clifton DK, Steiner RA.

Endocrinology. 2013 Aug;154(8):2784-94. doi: 10.1210/en.2013-1222. Epub 2013 Jun 4.

13.

Brain microvascular accumulation and distribution of the NOTCH3 ectodomain and granular osmiophilic material in CADASIL.

Yamamoto Y, Craggs LJ, Watanabe A, Booth T, Attems J, Low RW, Oakley AE, Kalaria RN.

J Neuropathol Exp Neurol. 2013 May;72(5):416-31. doi: 10.1097/NEN.0b013e31829020b5.

PMID:
23584202
14.

Quantitative vascular pathology and phenotyping familial and sporadic cerebral small vessel diseases.

Craggs LJ, Hagel C, Kuhlenbaeumer G, Borjesson-Hanson A, Andersen O, Viitanen M, Kalimo H, McLean CA, Slade JY, Hall RA, Oakley AE, Yamamoto Y, Deramecourt V, Kalaria RN.

Brain Pathol. 2013 Sep;23(5):547-57. doi: 10.1111/bpa.12041. Epub 2013 Mar 8.

PMID:
23387519
15.

Staging and natural history of cerebrovascular pathology in dementia.

Deramecourt V, Slade JY, Oakley AE, Perry RH, Ince PG, Maurage CA, Kalaria RN.

Neurology. 2012 Apr 3;78(14):1043-50. doi: 10.1212/WNL.0b013e31824e8e7f. Epub 2012 Feb 29.

16.

Hippocampal neuronal atrophy and cognitive function in delayed poststroke and aging-related dementias.

Gemmell E, Bosomworth H, Allan L, Hall R, Khundakar A, Oakley AE, Deramecourt V, Polvikoski TM, O'Brien JT, Kalaria RN.

Stroke. 2012 Mar;43(3):808-14. doi: 10.1161/STROKEAHA.111.636498. Epub 2011 Dec 29.

PMID:
22207507
17.

Cellular pathology within the anterior cingulate cortex of patients with late-life depression: a morphometric study.

Khundakar AA, Morris CM, Oakley AE, Thomas AJ.

Psychiatry Res. 2011 Nov 30;194(2):184-9. doi: 10.1016/j.pscychresns.2011.04.008. Epub 2011 Sep 15.

PMID:
21924875
18.

Membrane-initiated actions of estradiol (E2) in the regulation of LH secretion in ovariectomized (OVX) ewes.

Arreguin-Arevalo JA, Ashley RL, Wagenmaker ER, Oakley AE, Karsch FJ, Nett TM.

Reprod Biol Endocrinol. 2010 May 10;8:40. doi: 10.1186/1477-7827-8-40.

19.

The estrous cycle of the ewe is resistant to disruption by repeated, acute psychosocial stress.

Wagenmaker ER, Breen KM, Oakley AE, Tilbrook AJ, Karsch FJ.

Biol Reprod. 2010 Jun;82(6):1206-15. doi: 10.1095/biolreprod.109.078774. Epub 2010 Feb 17.

20.

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies.

Ihara M, Polvikoski TM, Hall R, Slade JY, Perry RH, Oakley AE, Englund E, O'Brien JT, Ince PG, Kalaria RN.

Acta Neuropathol. 2010 May;119(5):579-89. doi: 10.1007/s00401-009-0635-8. Epub 2010 Jan 21.

21.

Kisspeptin signaling in the brain.

Oakley AE, Clifton DK, Steiner RA.

Endocr Rev. 2009 Oct;30(6):713-43. doi: 10.1210/er.2009-0005. Epub 2009 Sep 21. Review.

22.

Dorsal motor nucleus of vagus protein aggregates in Lewy body disease with autonomic dysfunction.

Miller VM, Kenny RA, Oakley AE, Hall R, Kalaria RN, Allan LM.

Brain Res. 2009 Aug 25;1286:165-73. doi: 10.1016/j.brainres.2009.05.083. Epub 2009 Jun 6.

PMID:
19501577
23.

Neuropathological correlates of temporal pole white matter hyperintensities in CADASIL.

Yamamoto Y, Ihara M, Tham C, Low RW, Slade JY, Moss T, Oakley AE, Polvikoski T, Kalaria RN.

Stroke. 2009 Jun;40(6):2004-11. doi: 10.1161/STROKEAHA.108.528299. Epub 2009 Apr 9.

24.

Role of estradiol in cortisol-induced reduction of luteinizing hormone pulse frequency.

Oakley AE, Breen KM, Tilbrook AJ, Wagenmaker ER, Karsch FJ.

Endocrinology. 2009 Jun;150(6):2775-82. doi: 10.1210/en.2008-1754. Epub 2009 Jan 29.

25.

Cortisol interferes with the estradiol-induced surge of luteinizing hormone in the ewe.

Wagenmaker ER, Breen KM, Oakley AE, Pierce BN, Tilbrook AJ, Turner AI, Karsch FJ.

Biol Reprod. 2009 Mar;80(3):458-63. doi: 10.1095/biolreprod.108.074252. Epub 2008 Dec 3.

26.

Psychosocial stress inhibits amplitude of gonadotropin-releasing hormone pulses independent of cortisol action on the type II glucocorticoid receptor.

Wagenmaker ER, Breen KM, Oakley AE, Tilbrook AJ, Karsch FJ.

Endocrinology. 2009 Feb;150(2):762-9. doi: 10.1210/en.2008-0757. Epub 2008 Oct 1.

27.

Cortisol reduces gonadotropin-releasing hormone pulse frequency in follicular phase ewes: influence of ovarian steroids.

Oakley AE, Breen KM, Clarke IJ, Karsch FJ, Wagenmaker ER, Tilbrook AJ.

Endocrinology. 2009 Jan;150(1):341-9. doi: 10.1210/en.2008-0587. Epub 2008 Sep 18.

28.

Estradiol enables cortisol to act directly upon the pituitary to suppress pituitary responsiveness to GnRH in sheep.

Pierce BN, Stackpole CA, Breen KM, Clarke IJ, Karsch FJ, Rivalland ET, Turner AI, Caddy DJ, Wagenmaker ER, Oakley AE, Tilbrook AJ.

Neuroendocrinology. 2009;89(1):86-97. doi: 10.1159/000151543. Epub 2008 Aug 19.

PMID:
18714145
29.

Medullary autonomic pathology in carotid sinus hypersensitivity.

Miller VM, Kenny RA, Slade JY, Oakley AE, Kalaria RN.

Neuropathol Appl Neurobiol. 2008 Aug;34(4):403-11. Epub 2007 Nov 14.

PMID:
18005097
30.

Insight into the neuroendocrine site and cellular mechanism by which cortisol suppresses pituitary responsiveness to gonadotropin-releasing hormone.

Breen KM, Davis TL, Doro LC, Nett TM, Oakley AE, Padmanabhan V, Rispoli LA, Wagenmaker ER, Karsch FJ.

Endocrinology. 2008 Feb;149(2):767-73. Epub 2007 Oct 25.

31.

Individual dopaminergic neurons show raised iron levels in Parkinson disease.

Oakley AE, Collingwood JF, Dobson J, Love G, Perrott HR, Edwardson JA, Elstner M, Morris CM.

Neurology. 2007 May 22;68(21):1820-5.

PMID:
17515544
32.

Medullary microvessel degeneration in multiple system atrophy.

Miller VM, Kalaria RN, Hall R, Oakley AE, Kenny RA.

Neurobiol Dis. 2007 Jun;26(3):615-22. Epub 2007 Mar 21.

PMID:
17466525
33.

Does cortisol acting via the type II glucocorticoid receptor mediate suppression of pulsatile luteinizing hormone secretion in response to psychosocial stress?

Breen KM, Oakley AE, Pytiak AV, Tilbrook AJ, Wagenmaker ER, Karsch FJ.

Endocrinology. 2007 Apr;148(4):1882-90. Epub 2007 Jan 4.

PMID:
17204556
34.

Cholinergic neuronal deficits in CADASIL.

Keverne JS, Low WC, Ziabreva I, Court JA, Oakley AE, Kalaria RN.

Stroke. 2007 Jan;38(1):188-91. Epub 2006 Nov 22.

PMID:
17122431
35.

Effects of NOS inhibition on the cardiopulmonary system and brain microvascular markers after intermittent hypoxia in rats.

Barer GR, Fairlie J, Slade JY, Ahmed S, Laude EA, Emery CJ, Thwaites-Bee D, Oakley AE, Barer DH, Kalaria RN.

Brain Res. 2006 Jul 7;1098(1):196-203. Epub 2006 Jun 21.

PMID:
16793027
36.

Hypoxia of sleep apnoea: cardiopulmonary and cerebral changes after intermittent hypoxia in rats.

Kalaria RN, Spoors L, Laude EA, Emery CJ, Thwaites-Bee D, Fairlie J, Oakley AE, Barer DH, Barer GR.

Respir Physiol Neurobiol. 2004 Apr 20;140(1):53-62.

PMID:
15109928
37.

Chronic glial activation, neurodegeneration, and APP immunoreactive deposits following acute administration of double-stranded RNA.

Melton LM, Keith AB, Davis S, Oakley AE, Edwardson JA, Morris CM.

Glia. 2003 Oct;44(1):1-12.

PMID:
12951652
38.

CADASIL and genetics of cerebral ischaemia.

Kalaria RN, Low WC, Oakley AE, Slade JY, Ince PG, Morris CM, Mizuno T.

J Neural Transm Suppl. 2002;(63):75-90. Review.

PMID:
12597610
39.

Aggregation of A beta Alzheimer's disease-related peptide studied by dynamic light scattering.

Thunecke M, Lobbia A, Kosciessa U, Dyrks T, Oakley AE, Turner J, Saenger W, Georgalis Y.

J Pept Res. 1998 Dec;52(6):509-17.

PMID:
9924995
40.

Nicotinic and muscarinic cholinergic receptor binding in the human hippocampal formation during development and aging.

Court JA, Lloyd S, Johnson M, Griffiths M, Birdsall NJ, Piggott MA, Oakley AE, Ince PG, Perry EK, Perry RH.

Brain Res Dev Brain Res. 1997 Jul 18;101(1-2):93-105.

PMID:
9263584
41.
42.
43.

The role of the cholinergic system in the development of the human cerebellum.

Court JA, Perry EK, Spurden D, Griffiths M, Kerwin JM, Morris CM, Johnson M, Oakley AE, Birdsall NJ, Clementi F, et al.

Brain Res Dev Brain Res. 1995 Dec 21;90(1-2):159-67.

PMID:
8719339
44.

Amorphous aluminosilicates promote nucleation of amyloid beta protein and tachykinins.

Candy JM, Oakley AE, Edwardson JA.

Biochem Soc Trans. 1993 Feb;21(1):53S. No abstract available.

PMID:
8449336
45.

Brain iron homeostasis.

Morris CM, Candy JM, Keith AB, Oakley AE, Taylor GA, Pullen RG, Bloxham CA, Gocht A, Edwardson JA.

J Inorg Biochem. 1992 Aug 15-Sep;47(3-4):257-65. Review.

PMID:
1431885
46.

Aluminium accumulation in relation to senile plaque and neurofibrillary tangle formation in the brains of patients with renal failure.

Candy JM, McArthur FK, Oakley AE, Taylor GA, Chen CP, Mountfort SA, Thompson JE, Chalker PR, Bishop HE, Beyreuther K, et al.

J Neurol Sci. 1992 Feb;107(2):210-8.

PMID:
1564520
47.

Histochemical distribution of non-haem iron in the human brain.

Morris CM, Candy JM, Oakley AE, Bloxham CA, Edwardson JA.

Acta Anat (Basel). 1992;144(3):235-57.

PMID:
1529678
48.

The imaging and quantification of aluminium in the human brain using dynamic secondary ion mass spectrometry (SIMS).

Candy JM, Oakley AE, Mountfort SA, Taylor GA, Morris CM, Bishop HE, Edwardson JA.

Biol Cell. 1992;74(1):109-18.

PMID:
1511240
49.

Aluminium accumulation, beta-amyloid deposition and neurofibrillary changes in the central nervous system.

Edwardson JA, Candy JM, Ince PG, McArthur FK, Morris CM, Oakley AE, Taylor GA, Bjertness E.

Ciba Found Symp. 1992;169:165-79; discussion 179-85. Review.

PMID:
1490421
50.

Multicatalytic, high-Mr endopeptidase from postmortem human brain.

McDermott JR, Gibson AM, Oakley AE, Biggins JA.

J Neurochem. 1991 May;56(5):1509-17.

PMID:
2013752

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