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Items: 1 to 50 of 100

1.

Genome-wide Association Study Identifies HLA-DPB1 as a Significant Risk Factor for Severe Aplastic Anemia.

Savage SA, Viard M, O'hUigin C, Zhou W, Yeager M, Li SA, Wang T, Ramsuran V, Vince N, Vogt A, Hicks B, Burdett L, Chung C, Dean M, de Andrade KC, Freedman ND, Berndt SI, Rothman N, Lan Q, Cerhan JR, Slager SL, Zhang Y, Teras LR, Haagenson M, Chanock SJ, Spellman SR, Wang Y, Willis A, Askar M, Lee SJ, Carrington M, Gadalla SM.

Am J Hum Genet. 2020 Feb 6;106(2):264-271. doi: 10.1016/j.ajhg.2020.01.004. Epub 2020 Jan 30.

PMID:
32004448
2.

Role of HLA-B exon 1 in graft-versus-host disease after unrelated haemopoietic cell transplantation: a retrospective cohort study.

Petersdorf EW, Carrington M, O'hUigin C, Bengtsson M, De Santis D, Dubois V, Gooley T, Horowitz M, Hsu K, Madrigal JA, Maiers MJ, Malkki M, McKallor C, Morishima Y, Oudshoorn M, Spellman SR, Villard J, Stevenson P; International Histocompatibility Working Group in Hematopoietic Cell Transplantation.

Lancet Haematol. 2020 Jan;7(1):e50-e60. doi: 10.1016/S2352-3026(19)30208-X. Epub 2019 Oct 25.

PMID:
31669248
3.

The MHC in the era of next-generation sequencing: Implications for bridging structure with function.

Petersdorf EW, O'hUigin C.

Hum Immunol. 2019 Jan;80(1):67-78. doi: 10.1016/j.humimm.2018.10.002. Epub 2018 Oct 12. Review.

4.

The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance.

Yoshimura T, McLean MH, Dzutsev AK, Yao X, Chen K, Huang J, Gong W, Zhou J, Xiang Y, H Badger J, O'hUigin C, Thovarai V, Tessarollo L, Durum SK, Trinchieri G, Bian XW, Wang JM.

J Immunol. 2018 Mar 15;200(6):2174-2185. doi: 10.4049/jimmunol.1602073. Epub 2018 Feb 12.

5.

Posttranscriptional Regulation of HLA-A Protein Expression by Alternative Polyadenylation Signals Involving the RNA-Binding Protein Syncrip.

Kulkarni S, Ramsuran V, Rucevic M, Singh S, Lied A, Kulkarni V, O'hUigin C, Le Gall S, Carrington M.

J Immunol. 2017 Dec 1;199(11):3892-3899. doi: 10.4049/jimmunol.1700697. Epub 2017 Oct 20.

6.

Sequence and Phylogenetic Analysis of the Untranslated Promoter Regions for HLA Class I Genes.

Ramsuran V, Hernández-Sanchez PG, O'hUigin C, Sharma G, Spence N, Augusto DG, Gao X, García-Sepúlveda CA, Kaur G, Mehra NK, Carrington M.

J Immunol. 2017 Mar 15;198(6):2320-2329. doi: 10.4049/jimmunol.1601679. Epub 2017 Feb 1.

7.

Significance of positive selection and gene duplication in adaptive evolution: in memory of Austin L. Hughes.

Wolfe K, Ó'hUigín C.

Immunogenetics. 2016 Nov;68(10):749-753. Epub 2016 Jul 26. Review.

PMID:
27461477
8.

High HLA-DP Expression and Graft-versus-Host Disease.

Petersdorf EW, Malkki M, O'hUigin C, Carrington M, Gooley T, Haagenson MD, Horowitz MM, Spellman SR, Wang T, Stevenson P.

N Engl J Med. 2015 Aug 13;373(7):599-609. doi: 10.1056/NEJMoa1500140.

9.

Sequencing rare and common APOL1 coding variants to determine kidney disease risk.

Limou S, Nelson GW, Lecordier L, An P, O'hUigin CS, David VA, Binns-Roemer EA, Guiblet WM, Oleksyk TK, Pays E, Kopp JB, Winkler CA.

Kidney Int. 2015 Oct;88(4):754-63. doi: 10.1038/ki.2015.151. Epub 2015 May 20.

10.

Epigenetic regulation of differential HLA-A allelic expression levels.

Ramsuran V, Kulkarni S, O'huigin C, Yuki Y, Augusto DG, Gao X, Carrington M.

Hum Mol Genet. 2015 Aug 1;24(15):4268-75. doi: 10.1093/hmg/ddv158. Epub 2015 May 1.

11.

HLA-C expression levels define permissible mismatches in hematopoietic cell transplantation.

Petersdorf EW, Gooley TA, Malkki M, Bacigalupo AP, Cesbron A, Du Toit E, Ehninger G, Egeland T, Fischer GF, Gervais T, Haagenson MD, Horowitz MM, Hsu K, Jindra P, Madrigal A, Oudshoorn M, Ringdén O, Schroeder ML, Spellman SR, Tiercy JM, Velardi A, Witt CS, O'Huigin C, Apps R, Carrington M; International Histocompatibility Working Group in Hematopoietic Cell Transplantation.

Blood. 2014 Dec 18;124(26):3996-4003. doi: 10.1182/blood-2014-09-599969. Epub 2014 Oct 16.

12.

Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease.

Kulkarni S, Qi Y, O'hUigin C, Pereyra F, Ramsuran V, McLaren P, Fellay J, Nelson G, Chen H, Liao W, Bass S, Apps R, Gao X, Yuki Y, Lied A, Ganesan A, Hunt PW, Deeks SG, Wolinsky S, Walker BD, Carrington M.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20705-10. doi: 10.1073/pnas.1312237110. Epub 2013 Nov 18.

13.

The research of W.E. Mayer (1953-2012): a spectrum of immune systems.

O'hUigin C.

Immunogenetics. 2012 Dec;64(12):849-54. doi: 10.1007/s00251-012-0654-9. Epub 2012 Oct 10. Review.

PMID:
23053060
14.

The molecular origin and consequences of escape from miRNA regulation by HLA-C alleles.

O'huigin C, Kulkarni S, Xu Y, Deng Z, Kidd J, Kidd K, Gao X, Carrington M.

Am J Hum Genet. 2011 Sep 9;89(3):424-31. doi: 10.1016/j.ajhg.2011.07.024.

15.

Characterization and polymorphic analysis of 4.5 kb genomic full-length HLA-C in the Chinese Han population.

Xu Y, Deng Z, O'hUigin C, Wang D, Gao S, Zeng J, Yang B, Jin S, Zou H.

Tissue Antigens. 2011 Aug;78(2):102-14. doi: 10.1111/j.1399-0039.2011.01710.x. Epub 2011 Jun 9.

PMID:
21658009
16.

Spectrum of MHC class II variability in Darwin's finches and their close relatives.

Sato A, Tichy H, Grant PR, Grant BR, Sato T, O'hUigin C.

Mol Biol Evol. 2011 Jun;28(6):1943-56. doi: 10.1093/molbev/msr015. Epub 2011 Jan 27.

17.

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18.

Salcedo R, Worschech A, Cardone M, Jones Y, Gyulai Z, Dai RM, Wang E, Ma W, Haines D, O'hUigin C, Marincola FM, Trinchieri G.

J Exp Med. 2010 Aug 2;207(8):1625-36. doi: 10.1084/jem.20100199. Epub 2010 Jul 12.

18.

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.

Thomas R, Apps R, Qi Y, Gao X, Male V, O'hUigin C, O'Connor G, Ge D, Fellay J, Martin JN, Margolick J, Goedert JJ, Buchbinder S, Kirk GD, Martin MP, Telenti A, Deeks SG, Walker BD, Goldstein D, McVicar DW, Moffett A, Carrington M.

Nat Genet. 2009 Dec;41(12):1290-4. doi: 10.1038/ng.486.

19.

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus.

Thomas DL, Thio CL, Martin MP, Qi Y, Ge D, O'Huigin C, Kidd J, Kidd K, Khakoo SI, Alexander G, Goedert JJ, Kirk GD, Donfield SM, Rosen HR, Tobler LH, Busch MP, McHutchison JG, Goldstein DB, Carrington M.

Nature. 2009 Oct 8;461(7265):798-801. doi: 10.1038/nature08463.

20.

Unique features of TRIM5alpha among closely related human TRIM family members.

Li X, Gold B, O'hUigin C, Diaz-Griffero F, Song B, Si Z, Li Y, Yuan W, Stremlau M, Mische C, Javanbakht H, Scally M, Winkler C, Dean M, Sodroski J.

Virology. 2007 Apr 10;360(2):419-33. Epub 2006 Dec 6.

21.

Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection.

Javanbakht H, An P, Gold B, Petersen DC, O'Huigin C, Nelson GW, O'Brien SJ, Kirk GD, Detels R, Buchbinder S, Donfield S, Shulenin S, Song B, Perron MJ, Stremlau M, Sodroski J, Dean M, Winkler C.

Virology. 2006 Oct 10;354(1):15-27. Epub 2006 Aug 2.

22.

Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection.

Si Z, Vandegraaff N, O'huigin C, Song B, Yuan W, Xu C, Perron M, Li X, Marasco WA, Engelman A, Dean M, Sodroski J.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7454-9. Epub 2006 Apr 28.

23.

The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates.

Song B, Gold B, O'Huigin C, Javanbakht H, Li X, Stremlau M, Winkler C, Dean M, Sodroski J.

J Virol. 2005 May;79(10):6111-21.

24.

Ancestral population sizes and species divergence times in the primate lineage on the basis of intron and BAC end sequences.

Satta Y, Hickerson M, Watanabe H, O'hUigin C, Klein J.

J Mol Evol. 2004 Oct;59(4):478-87.

PMID:
15638459
25.

Evidence that the separation of Mhc class II from class I loci in the zebrafish, Danio rerio, occurred by translocation.

Kuroda N, Figueroa F, O'hUigin C, Klein J.

Immunogenetics. 2002 Sep;54(6):418-30. Epub 2002 Jul 16.

PMID:
12242592
26.

Contribution of homoplasy and of ancestral polymorphism to the evolution of genes in anthropoid primates.

O'hUigin C, Satta Y, Takahata N, Klein J.

Mol Biol Evol. 2002 Sep;19(9):1501-13.

PMID:
12200478
27.

Identification of two Ikaros-like transcription factors in lamprey.

Mayer WE, O'Huigin C, Tichy H, Terzic J, Saraga-Babic M.

Scand J Immunol. 2002 Feb;55(2):162-70.

28.

The surface structure of trypanosomes in relation to their molecular phylogeny.

Overath P, Haag J, Lischke A, O'hUigin C.

Int J Parasitol. 2001 May 1;31(5-6):468-71. Review.

PMID:
11334931
29.

On the origin of Darwin's finches.

Sato A, Tichy H, O'hUigin C, Grant PR, Grant BR, Klein J.

Mol Biol Evol. 2001 Mar;18(3):299-311.

PMID:
11230531
30.

Independent origin of functional MHC class II genes in humans and New World monkeys.

Kriener K, O'hUigin C, Klein J.

Hum Immunol. 2001 Jan;62(1):1-14.

PMID:
11165710
31.

Convergent evolution of major histocompatibility complex molecules in humans and New World monkeys.

Kriener K, O'hUigin C, Tichy H, Klein J.

Immunogenetics. 2000 Mar;51(3):169-78.

PMID:
10752625
32.

Biglycan-like extracellular matrix genes of agnathans and teleosts.

Shintani S, Sato A, Toyosawa S, O'hUigin C, Klein J.

J Mol Evol. 2000 Oct;51(4):363-73.

PMID:
11040287
33.

The implications of intergenic polymorphism for major histocompatibility complex evolution.

O'hUigin C, Satta Y, Hausmann A, Dawkins RL, Klein J.

Genetics. 2000 Oct;156(2):867-77.

34.

Mhc class II B gene evolution in East African cichlid fishes.

Figueroa F, Mayer WE, Sültmann H, O'hUigin C, Tichy H, Satta Y, Takezaki N, Takahata N, Klein J.

Immunogenetics. 2000 Jun;51(7):556-75.

PMID:
10912507
35.

Do lampreys have lymphocytes? The Spi evidence.

Shintani S, Terzic J, Sato A, Saraga-Babic M, O'hUigin C, Tichy H, Klein J.

Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7417-22.

36.
37.

Expression of the dentin matrix protein 1 gene in birds.

Toyosawa S, Sato A, O'hUigin C, Tichy H, Klein J.

J Mol Evol. 2000 Jan;50(1):31-8.

PMID:
10654257
38.

Characterization of dentin matrix protein 1 gene in crocodilia.

Toyosawa S, O'hUigin C, Tichy H, Klein J.

Gene. 1999 Jul 8;234(2):307-14.

PMID:
10395903
39.

Origin of gene overlap: the case of TCP1 and ACAT2.

Shintani S, O'hUigin C, Toyosawa S, Michalová V, Klein J.

Genetics. 1999 Jun;152(2):743-54.

40.

Phylogeny of Darwin's finches as revealed by mtDNA sequences.

Sato A, O'hUigin C, Figueroa F, Grant PR, Grant BR, Tichy H, Klein J.

Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5101-6.

41.

The dentin matrix protein 1 gene of prototherian and metatherian mammals.

Toyosawa S, O'hUigin C, Klein J.

J Mol Evol. 1999 Feb;48(2):160-7.

PMID:
9929384
42.

Isolation of mhc class II DMA and DMB cDNA sequences in a marsupial: the gray short-tailed opossum (Monodelphis domestica).

O'hUigin C, Sültmann H, Tichy H, Murray BW.

J Mol Evol. 1998 Nov;47(5):578-85.

PMID:
9797408
43.

Identification and characterization of amelogenin genes in monotremes, reptiles, and amphibians.

Toyosawa S, O'hUigin C, Figueroa F, Tichy H, Klein J.

Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13056-61.

44.

Cloning of major histocompatibility complex (Mhc) genes from threespine stickleback, Gasterosteus aculeatus.

Sato A, Figueroa F, O'hUigin C, Steck N, Klein J.

Mol Mar Biol Biotechnol. 1998 Sep;7(3):221-31.

PMID:
9701617
45.

Evolution by gene duplication in the major histocompatibility complex.

Klein J, Sato A, O'hUigin C.

Cytogenet Cell Genet. 1998;80(1-4):123-7. Review. No abstract available.

PMID:
9678345
46.

The molecular phylogeny of trypanosomes: evidence for an early divergence of the Salivaria.

Haag J, O'hUigin C, Overath P.

Mol Biochem Parasitol. 1998 Mar 1;91(1):37-49. Review.

PMID:
9574924
47.

Polymorphism of the HLA class II loci in Siberian populations.

Grahovac B, Sukernik RI, O'hUigin C, Zaleska-Rutczynska Z, Blagitko N, Raldugina O, Kosutic T, Satta Y, Figueroa F, Takahata N, Klein J.

Hum Genet. 1998 Jan;102(1):27-43.

PMID:
9490295
48.

Evidence for convergent evolution of A and B blood group antigens in primates.

O'hUigin C, Sato A, Klein J.

Hum Genet. 1997 Dec;101(2):141-8.

PMID:
9402958
49.

HLA-DRB9--possible remnant of an ancient functional DRB subregion.

Gongora R, Figueroa F, O'Huigin C, Klein J.

Scand J Immunol. 1997 May;45(5):504-10.

50.

Polymorphism of the HLA-DRB1 locus in Colombian, Ecuadorian, and Chilean Amerinds.

Blagitko N, O'hUigin C, Figueroa F, Horai S, Sonoda S, Tajima K, Watkins D, Klein J.

Hum Immunol. 1997 Apr 15;54(1):74-81.

PMID:
9154461

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