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Femoroacetabular Impingement.

O'Rourke RJ, El Bitar Y.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Oct 11.


Lower Radiation Dosing in Cardiac Computed Tomographic Angiography: the CONVERGE Registry.

Madaj P, Li D, Nakanishi R, Andreini D, Pontone G, Conte E, O'Rourke R, Hamilton-Craig C, Nimmagadda M, Kim N, Fatima B, Dailing C, Budoff M.

J Nucl Med Technol. 2019 Oct 11. pii: jnumed.119.229500. doi: 10.2967/jnumed.119.229500. [Epub ahead of print]


Corrigendum to "Coronary CT in Australia has high positive predictive value unaffected by site volume: An analysis of 510 positive CTCA scans with invasive angiographic correlation" [IJC Heart Vasc. 20 (2018) 46-49].

Fletcher MP, O'Rourke R, Gaikwad N, David M, Walters DL, Hamilton-Craig C.

Int J Cardiol Heart Vasc. 2019 Apr 18;23:100352. doi: 10.1016/j.ijcha.2019.100352. eCollection 2019 Jun.


Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma.

Bandopadhayay P, Piccioni F, O'Rourke R, Ho P, Gonzalez EM, Buchan G, Qian K, Gionet G, Girard E, Coxon M, Rees MG, Brenan L, Dubois F, Shapira O, Greenwald NF, Pages M, Balboni Iniguez A, Paolella BR, Meng A, Sinai C, Roti G, Dharia NV, Creech A, Tanenbaum B, Khadka P, Tracy A, Tiv HL, Hong AL, Coy S, Rashid R, Lin JR, Cowley GS, Lam FC, Goodale A, Lee Y, Schoolcraft K, Vazquez F, Hahn WC, Tsherniak A, Bradner JE, Yaffe MB, Milde T, Pfister SM, Qi J, Schenone M, Carr SA, Ligon KL, Kieran MW, Santagata S, Olson JM, Gokhale PC, Jaffe JD, Root DE, Stegmaier K, Johannessen CM, Beroukhim R.

Nat Commun. 2019 Jun 3;10(1):2400. doi: 10.1038/s41467-019-10307-9.


Enhancing face validity of mouse models of Alzheimer's disease with natural genetic variation.

Onos KD, Uyar A, Keezer KJ, Jackson HM, Preuss C, Acklin CJ, O'Rourke R, Buchanan R, Cossette TL, Sukoff Rizzo SJ, Soto I, Carter GW, Howell GR.

PLoS Genet. 2019 May 31;15(5):e1008155. doi: 10.1371/journal.pgen.1008155. eCollection 2019 May.


Comparison of Whole Heart Computed Tomography Scanners for Image Quality Lower Radiation Dosing in Coronary Computed Tomography Angiography: The CONVERGE Registry.

Patel N, Li D, Nakanishi R, Fatima B, Andreini D, Pontone G, Conte E, O'Rourke R, Jayawardena E, Hamilton-Craig C, Nimmagadda M, Budoff MJ.

Acad Radiol. 2019 Jan 23. pii: S1076-6332(19)30021-2. doi: 10.1016/j.acra.2019.01.002. [Epub ahead of print]


GM-CSF Administration Improves Defects in Innate Immunity and Sepsis Survival in Obese Diabetic Mice.

Frydrych LM, Bian G, Fattahi F, Morris SB, O'Rourke RW, Lumeng CN, Kunkel SL, Ward PA, Delano MJ.

J Immunol. 2019 Feb 1;202(3):931-942. doi: 10.4049/jimmunol.1800713. Epub 2018 Dec 21.


Pulmonary Artery Pseudoaneurysms in the Setting of Gout Polyarthropathy: A Case Report.

Bai A, Lan L, Poon K, Pynadath Joseph V, O'Rourke R, Aftab K.

J Clin Med Res. 2018 Oct;10(10):781-785. doi: 10.14740/jocmr3513w. Epub 2018 Sep 10.


Adipose tissue and the physiologic underpinnings of metabolic disease.

O'Rourke RW.

Surg Obes Relat Dis. 2018 Nov;14(11):1755-1763. doi: 10.1016/j.soard.2018.07.032. Epub 2018 Aug 7. Review.


Coronary CT in Australia has high positive predictive value unaffected by site volume: An analysis of 510 positive CTCA scans with invasive angiographic correlation.

Fletcher MP, O'Rourke R, Gaikwad N, Walters DL, Hamilton-Craig C.

Int J Cardiol Heart Vasc. 2018 Aug 18;20:46-49. doi: 10.1016/j.ijcha.2018.03.005. eCollection 2018 Sep. Erratum in: Int J Cardiol Heart Vasc. 2019 Apr 18;23:100352.


Genetic and transcriptional evolution alters cancer cell line drug response.

Ben-David U, Siranosian B, Ha G, Tang H, Oren Y, Hinohara K, Strathdee CA, Dempster J, Lyons NJ, Burns R, Nag A, Kugener G, Cimini B, Tsvetkov P, Maruvka YE, O'Rourke R, Garrity A, Tubelli AA, Bandopadhayay P, Tsherniak A, Vazquez F, Wong B, Birger C, Ghandi M, Thorner AR, Bittker JA, Meyerson M, Getz G, Beroukhim R, Golub TR.

Nature. 2018 Aug;560(7718):325-330. doi: 10.1038/s41586-018-0409-3. Epub 2018 Aug 8.


Workplace learning and career progression: qualitative perspectives of UK dietitians.

Boocock RC, O'Rourke RK.

J Hum Nutr Diet. 2018 Oct;31(5):704-711. doi: 10.1111/jhn.12567. Epub 2018 Jun 10.


Serum biomarkers of inflammation and adiposity in the LABS cohort: associations with metabolic disease and surgical outcomes.

O'Rourke RW, Johnson GS, Purnell JQ, Courcoulas AP, Dakin GF, Garcia L, Hinojosa M, Mitchell JE, Pomp A, Pories WJ, Spaniolas K, Flum DR, Wahed AS, Wolfe BM.

Int J Obes (Lond). 2019 Feb;43(2):285-296. doi: 10.1038/s41366-018-0088-z. Epub 2018 May 17.


SvABA: genome-wide detection of structural variants and indels by local assembly.

Wala JA, Bandopadhayay P, Greenwald NF, O'Rourke R, Sharpe T, Stewart C, Schumacher S, Li Y, Weischenfeldt J, Yao X, Nusbaum C, Campbell P, Getz G, Meyerson M, Zhang CZ, Imielinski M, Beroukhim R.

Genome Res. 2018 Apr;28(4):581-591. doi: 10.1101/gr.221028.117. Epub 2018 Mar 13.


The pseudokinases SgK269 and SgK223: A novel oncogenic alliance in human cancer.

O'Rourke RL, Daly RJ.

Cell Adh Migr. 2018;12(6):524-528. doi: 10.1080/19336918.2017.1394570. Epub 2017 Dec 21. Review.


Is Digital Tomosynthesis on Par With Computed Tomography for the Detection and Measurement of Pulmonary Nodules?

Lee XW, Marshall HM, Leong SC, O'Rourke RL, Steinke K, Mirjalili N, Bowman RV, Yang IA, Fong KM.

J Thorac Imaging. 2017 Nov;32(6):W67-W68. doi: 10.1097/RTI.0000000000000298.


A randomised controlled trial of an online menu planning intervention to improve childcare service adherence to dietary guidelines: a study protocol.

Yoong SL, Grady A, Wiggers J, Flood V, Rissel C, Finch M, Searles A, Salajan D, O'Rourke R, Daly J, Gilham K, Stacey F, Fielding A, Pond N, Wyse R, Seward K, Wolfenden L.

BMJ Open. 2017 Sep 11;7(9):e017498. doi: 10.1136/bmjopen-2017-017498.


Adipocyte hypertrophy-hyperplasia balance contributes to weight loss after bariatric surgery.

Muir LA, Baker NA, Washabaugh AR, Neeley CK, Flesher CG, DelProposto JB, Geletka LM, Ghaferi AA, Finks JF, Singer K, Varban OA, Lumeng CN, O'Rourke RW.

Adipocyte. 2017 Apr 3;6(2):134-140. doi: 10.1080/21623945.2017.1287639. Epub 2017 Jan 27.


Weight loss independent changes in adipose tissue macrophage and T cell populations after sleeve gastrectomy in mice.

Frikke-Schmidt H, Zamarron BF, O'Rourke RW, Sandoval DA, Lumeng CN, Seeley RJ.

Mol Metab. 2017 Feb 16;6(4):317-326. doi: 10.1016/j.molmet.2017.02.004. eCollection 2017 Apr.


Diabetes-Specific Regulation of Adipocyte Metabolism by the Adipose Tissue Extracellular Matrix.

Baker NA, Muir LA, Washabaugh AR, Neeley CK, Chen SY, Flesher CG, Vorwald J, Finks JF, Ghaferi AA, Mulholland MW, Varban OA, Lumeng CN, O'Rourke RW.

J Clin Endocrinol Metab. 2017 Mar 1;102(3):1032-1043. doi: 10.1210/jc.2016-2915.


Differentiation and Metabolic Interrogation of Human Adipocytes.

Baker NA, Muir LA, Lumeng CN, O'Rourke RW.

Methods Mol Biol. 2017;1566:61-76. doi: 10.1007/978-1-4939-6820-6_7.


Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.

Ramkissoon SH, Bandopadhayay P, Hwang J, Ramkissoon LA, Greenwald NF, Schumacher SE, O'Rourke R, Pinches N, Ho P, Malkin H, Sinai C, Filbin M, Plant A, Bi WL, Chang MS, Yang E, Wright KD, Manley PE, Ducar M, Alexandrescu S, Lidov H, Delalle I, Goumnerova LC, Church AJ, Janeway KA, Harris MH, MacConaill LE, Folkerth RD, Lindeman NI, Stiles CD, Kieran MW, Ligon AH, Santagata S, Dubuc AM, Chi SN, Beroukhim R, Ligon KL.

Neuro Oncol. 2017 Jul 1;19(7):986-996. doi: 10.1093/neuonc/now294.


Adipose Tissue Dendritic Cells Are Independent Contributors to Obesity-Induced Inflammation and Insulin Resistance.

Cho KW, Zamarron BF, Muir LA, Singer K, Porsche CE, DelProposto JB, Geletka L, Meyer KA, O'Rourke RW, Lumeng CN.

J Immunol. 2016 Nov 1;197(9):3650-3661. Epub 2016 Sep 28.


Exercise cardiac MRI-derived right ventriculo-arterial coupling ratio detects early right ventricular maladaptation in PAH.

Lin AC, Strugnell WE, Seale H, Schmitt B, Schmidt M, O'Rourke R, Slaughter RE, Kermeen F, Hamilton-Craig C, Morris NR.

Eur Respir J. 2016 Dec;48(6):1797-1800. doi: 10.1183/13993003.01145-2016. Epub 2016 Sep 22. No abstract available.


Adipocytes promote pancreatic cancer cell proliferation via glutamine transfer.

Meyer KA, Neeley CK, Baker NA, Washabaugh AR, Flesher CG, Nelson BS, Frankel TL, Lumeng CN, Lyssiotis CA, Wynn ML, Rhim AD, O'Rourke RW.

Biochem Biophys Rep. 2016 Sep;7:144-149. Epub 2016 Jun 7.


Does bariatric surgery improve adipose tissue function?

Frikke-Schmidt H, O'Rourke RW, Lumeng CN, Sandoval DA, Seeley RJ.

Obes Rev. 2016 Sep;17(9):795-809. doi: 10.1111/obr.12429. Epub 2016 Jun 8. Review.


Multi-Institutional FASTQ File Exchange as a Means of Proficiency Testing for Next-Generation Sequencing Bioinformatics and Variant Interpretation.

Davies KD, Farooqi MS, Gruidl M, Hill CE, Woolworth-Hirschhorn J, Jones H, Jones KL, Magliocco A, Mitui M, O'Neill PH, O'Rourke R, Patel NM, Qin D, Ramos E, Rossi MR, Schneider TM, Smith GH, Zhang L, Park JY, Aisner DL.

J Mol Diagn. 2016 Jul;18(4):572-9. doi: 10.1016/j.jmoldx.2016.03.002. Epub 2016 May 4.


The effects of Parachlorella kessleri cultivation on brewery wastewater.

O'Rourke R, Gaffney M, Murphy R.

Water Sci Technol. 2016;73(6):1401-8. doi: 10.2166/wst.2015.618.


Optimal medical therapy with or without percutaneous coronary intervention in women with stable coronary disease: A pre-specified subset analysis of the Clinical Outcomes Utilizing Revascularization and Aggressive druG Evaluation (COURAGE) trial.

Acharjee S, Teo KK, Jacobs AK, Hartigan PM, Barn K, Gosselin G, Tanguay JF, Maron DJ, Kostuk WJ, Chaitman BR, Mancini GB, Spertus JA, Dada MR, Bates ER, Booth DC, Weintraub WS, O'Rourke RA, Boden WE; COURAGE Trial Research Group.

Am Heart J. 2016 Mar;173:108-17. doi: 10.1016/j.ahj.2015.07.020. Epub 2015 Jul 26.


Adipose tissue fibrosis, hypertrophy, and hyperplasia: Correlations with diabetes in human obesity.

Muir LA, Neeley CK, Meyer KA, Baker NA, Brosius AM, Washabaugh AR, Varban OA, Finks JF, Zamarron BF, Flesher CG, Chang JS, DelProposto JB, Geletka L, Martinez-Santibanez G, Kaciroti N, Lumeng CN, O'Rourke RW.

Obesity (Silver Spring). 2016 Mar;24(3):597-605. doi: 10.1002/oby.21377.


MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.

Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, Silva A, Boucher K, Henn RE, Kang YJ, Knoff D, Paolella BR, Gladden-Young A, Varlet P, Pages M, Horowitz PM, Federation A, Malkin H, Tracy AA, Seepo S, Ducar M, Van Hummelen P, Santi M, Buccoliero AM, Scagnet M, Bowers DC, Giannini C, Puget S, Hawkins C, Tabori U, Klekner A, Bognar L, Burger PC, Eberhart C, Rodriguez FJ, Hill DA, Mueller S, Haas-Kogan DA, Phillips JJ, Santagata S, Stiles CD, Bradner JE, Jabado N, Goren A, Grill J, Ligon AH, Goumnerova L, Waanders AJ, Storm PB, Kieran MW, Ligon KL, Beroukhim R, Resnick AC.

Nat Genet. 2016 Mar;48(3):273-82. doi: 10.1038/ng.3500. Epub 2016 Feb 1.


CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity.

Morris DL, Oatmen KE, Mergian TA, Cho KW, DelProposto JL, Singer K, Evans-Molina C, O'Rourke RW, Lumeng CN.

J Leukoc Biol. 2016 Jun;99(6):1107-19. doi: 10.1189/jlb.3A0115-009R. Epub 2015 Dec 11.


Fish consumption as a driver of risk-management decisions and human health-based water quality criteria.

Judd N, Lowney Y, Anderson P, Baird S, Bay SM, Breidt J, Buonanduci M, Dong Z, Essig D, Garry MR, Jim RC, Kirkwood G, Moore S, Niemi C, O'Rourke R, Ruffle B, Schaider LA, Vidal-Dorsch DE.

Environ Toxicol Chem. 2015 Nov;34(11):2427-36. doi: 10.1002/etc.3155.


High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling.

Zhao Y, Londono P, Cao Y, Sharpe EJ, Proenza C, O'Rourke R, Jones KL, Jeong MY, Walker LA, Buttrick PM, McKinsey TA, Song K.

Nat Commun. 2015 Sep 10;6:8243. doi: 10.1038/ncomms9243.


Preoperative factors and 3-year weight change in the Longitudinal Assessment of Bariatric Surgery (LABS) consortium.

Courcoulas AP, Christian NJ, O'Rourke RW, Dakin G, Patchen Dellinger E, Flum DR, Melissa Kalarchian PD, Mitchell JE, Patterson E, Pomp A, Pories WJ, Spaniolas K, Steffen K, Wolfe BM, Belle SH.

Surg Obes Relat Dis. 2015 Sep-Oct;11(5):1109-18. doi: 10.1016/j.soard.2015.01.011. Epub 2015 Jan 23.


An MHC II-dependent activation loop between adipose tissue macrophages and CD4+ T cells controls obesity-induced inflammation.

Cho KW, Morris DL, DelProposto JL, Geletka L, Zamarron B, Martinez-Santibanez G, Meyer KA, Singer K, O'Rourke RW, Lumeng CN.

Cell Rep. 2014 Oct 23;9(2):605-17. doi: 10.1016/j.celrep.2014.09.004. Epub 2014 Oct 9.


Obesity and cancer: at the crossroads of cellular metabolism and proliferation.

O'Rourke RW.

Surg Obes Relat Dis. 2014 Nov-Dec;10(6):1208-19. doi: 10.1016/j.soard.2014.08.012. Epub 2014 Aug 27. Review. No abstract available.


Endometrial hyperplasia, endometrial cancer, and obesity: convergent mechanisms regulating energy homeostasis and cellular proliferation.

O'Rourke RW.

Surg Obes Relat Dis. 2014 Sep-Oct;10(5):926-8. doi: 10.1016/j.soard.2014.03.022. Epub 2014 Apr 5. No abstract available.


Effect of reversible intermittent intra-abdominal vagal nerve blockade on morbid obesity: the ReCharge randomized clinical trial.

Ikramuddin S, Blackstone RP, Brancatisano A, Toouli J, Shah SN, Wolfe BM, Fujioka K, Maher JW, Swain J, Que FG, Morton JM, Leslie DB, Brancatisano R, Kow L, O'Rourke RW, Deveney C, Takata M, Miller CJ, Knudson MB, Tweden KS, Shikora SA, Sarr MG, Billington CJ.

JAMA. 2014 Sep 3;312(9):915-22. doi: 10.1001/jama.2014.10540. Erratum in: JAMA. 2015 Jan 6;313(1):95.


Coronary artery calcification on computed tomography correlates with mortality in chronic obstructive pulmonary disease.

OʼHare PE, Ayres JF, OʼRourke RL, Slaughter RE, Marshall HM, Bowman RV, Fong KM, Yang IA.

J Comput Assist Tomogr. 2014 Sep-Oct;38(5):753-9. doi: 10.1097/RCT.0000000000000119.


Systemic NK cell ablation attenuates intra-abdominal adipose tissue macrophage infiltration in murine obesity.

O'Rourke RW, Meyer KA, Neeley CK, Gaston GD, Sekhri P, Szumowski M, Zamarron B, Lumeng CN, Marks DL.

Obesity (Silver Spring). 2014 Oct;22(10):2109-14. doi: 10.1002/oby.20823. Epub 2014 Jun 24.


Learning to work with electronic patient records and prescription charts: experiences and perceptions of hospital pharmacists.

Burgin A, O'Rourke R, Tully MP.

Res Social Adm Pharm. 2014 Sep-Oct;10(5):741-55. doi: 10.1016/j.sapharm.2013.11.005. Epub 2013 Dec 3.


Metabolic thrift and the genetic basis of human obesity.

Oʼrourke RW.

Ann Surg. 2014 Apr;259(4):642-8. doi: 10.1097/SLA.0000000000000361. Review.


An emerging role for bone in interorgan communication and the pathogenesis of metabolic disease.

O'Rourke RW.

Surg Obes Relat Dis. 2014 Mar-Apr;10(2):303-6. doi: 10.1016/j.soard.2013.08.006. Epub 2013 Aug 23. No abstract available.


Second-degree bachelor of science in nursing students' preconceived attitudes toward the homeless and poor: a pilot study.

Boylston MT, O'Rourke R.

J Prof Nurs. 2013 Sep-Oct;29(5):309-17. doi: 10.1016/j.profnurs.2012.05.009. Epub 2013 Aug 29.


Adipose tissue NK cells manifest an activated phenotype in human obesity.

O'Rourke RW, Gaston GD, Meyer KA, White AE, Marks DL.

Metabolism. 2013 Nov;62(11):1557-61. doi: 10.1016/j.metabol.2013.07.011. Epub 2013 Sep 5.


Ovarian cycle-specific regulation of adipose tissue lipid storage by testosterone in female nonhuman primates.

Varlamov O, Chu MP, McGee WK, Cameron JL, O'Rourke RW, Meyer KA, Bishop CV, Stouffer RL, Roberts CT Jr.

Endocrinology. 2013 Nov;154(11):4126-35. doi: 10.1210/en.2013-1428. Epub 2013 Sep 5.


Hexosamine biosynthesis is a possible mechanism underlying hypoxia's effects on lipid metabolism in human adipocytes.

O'Rourke RW, Meyer KA, Gaston G, White AE, Lumeng CN, Marks DL.

PLoS One. 2013 Aug 14;8(8):e71165. doi: 10.1371/journal.pone.0071165. eCollection 2013.


Obesity heats up adipose tissue lymphocytes.

O'Rourke RW, Lumeng CN.

Gastroenterology. 2013 Aug;145(2):282-5. doi: 10.1053/j.gastro.2013.06.026. Epub 2013 Jun 24. No abstract available.


Bariatric surgery in the era of personalized medicine.

Butler AA, O'Rourke RW.

Gastroenterology. 2013 Mar;144(3):497-500. doi: 10.1053/j.gastro.2013.01.027. Epub 2013 Jan 21. No abstract available.

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