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Items: 1 to 50 of 416

1.

A Randomized Double-Blind Placebo-Controlled Phase II Trial of Dendritic Cell Vaccine ICT-107 in Newly Diagnosed Patients with Glioblastoma.

Wen PY, Reardon DA, Armstrong TS, Phuphanich S, Aiken RD, Landolfi JC, Curry WT, Zhu JJ, Glantz M, Peereboom DM, Markert JM, LaRocca R, O'Rourke DM, Fink K, Kim L, Gruber M, Lesser GJ, Pan E, Kesari S, Muzikansky A, Pinilla C, Santos RG, Yu JS.

Clin Cancer Res. 2019 Jul 18. doi: 10.1158/1078-0432.CCR-19-0261. [Epub ahead of print]

PMID:
31320597
2.

Evaluating the Association Between the Extent of Resection and Survival in Gliosarcoma.

Ahmed FI, Abdullah KG, Durgin J, Salinas RD, O'Rourke DM, Brem S.

Cureus. 2019 Apr 3;11(4):e4374. doi: 10.7759/cureus.4374.

3.

Arterial Spin Labeling and Dynamic Susceptibility Contrast-enhanced MR Imaging for evaluation of arteriovenous shunting and tumor hypoxia in glioblastoma.

Nabavizadeh SA, Akbari H, Ware JB, Nasrallah M, Guiry S, Bagley SJ, Desai A, Levy S, Sarchiapone W, Prior T, Detre J, Wolf RL, O'Rourke DM, Brem S, Davatzikos C.

Sci Rep. 2019 Jun 19;9(1):8747. doi: 10.1038/s41598-019-45312-x.

4.

Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma.

Nasrallah MP, Binder ZA, Oldridge DA, Zhao J, Lieberman DB, Roth JJ, Watt CD, Sukhadia S, Klinman E, Daber RD, Desai A, Brem S, O'Rourke DM, Morrissette JJD.

Acad Pathol. 2019 May 27;6:2374289519848353. doi: 10.1177/2374289519848353. eCollection 2019 Jan-Dec.

5.

Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America.

Flegontov P, Altınışık NE, Changmai P, Rohland N, Mallick S, Adamski N, Bolnick DA, Broomandkhoshbacht N, Candilio F, Culleton BJ, Flegontova O, Friesen TM, Jeong C, Harper TK, Keating D, Kennett DJ, Kim AM, Lamnidis TC, Lawson AM, Olalde I, Oppenheimer J, Potter BA, Raff J, Sattler RA, Skoglund P, Stewardson K, Vajda EJ, Vasilyev S, Veselovskaya E, Hayes MG, O'Rourke DH, Krause J, Pinhasi R, Reich D, Schiffels S.

Nature. 2019 Jun;570(7760):236-240. doi: 10.1038/s41586-019-1251-y. Epub 2019 Jun 5.

PMID:
31168094
6.

Enhanced perioperative management of children with autism: a pilot study.

Whippey A, Bernstein LM, O'Rourke D, Reddy D.

Can J Anaesth. 2019 Oct;66(10):1184-1193. doi: 10.1007/s12630-019-01410-y. Epub 2019 May 31.

PMID:
31152370
7.

Assessing variability in surgical decision making among attending neurosurgeons at an academic center.

Ramayya AG, Chen HI, Marcotte PJ, Brem S, Zager EL, Osiemo B, Piazza M, Sharma N, McClintock SD, Schuster JM, Ali ZS, Connolly P, Heuer GG, Grady MS, Kung DK, Ozturk AK, O'Rourke DM, Malhotra NR.

J Neurosurg. 2019 May 31:1-7. doi: 10.3171/2019.2.JNS182658. [Epub ahead of print]

PMID:
31151100
8.

Alignment of European Regulatory and Health Technology Assessments: A Review of Licensed Products for Alzheimer's Disease.

Dekker MJHJ, Bouvy JC, O'Rourke D, Thompson R, Makady A, Jonsson P, Gispen-de Wied CC.

Front Med (Lausanne). 2019 May 7;6:73. doi: 10.3389/fmed.2019.00073. eCollection 2019.

9.

For whom the egg thaws: insights from an analysis of 10 years of frozen egg thaw data from two UK clinics, 2008-2017.

Gürtin ZB, Morgan L, O'Rourke D, Wang J, Ahuja K.

J Assist Reprod Genet. 2019 Jun;36(6):1069-1080. doi: 10.1007/s10815-019-01429-6. Epub 2019 May 23.

PMID:
31119440
10.

The LACE+ index fails to predict 30-90 day readmission for supratentorial craniotomy patients: A retrospective series of 238 surgical procedures.

Caplan IF, Zadnik Sullivan P, Glauser G, Choudhri O, Kung D, O'Rourke DM, Osiemo B, Goodrich S, McClintock SD, Malhotra NR.

Clin Neurol Neurosurg. 2019 Jul;182:79-83. doi: 10.1016/j.clineuro.2019.04.026. Epub 2019 May 1.

PMID:
31102908
11.

Lipodisqs for eukaryote lipidomics with retention of viability: Sensitivity and resistance to Leucobacter infection linked to C.elegans cuticle composition.

Bada Juarez JF, O'Rourke D, Judge PJ, Liu LC, Hodgkin J, Watts A.

Chem Phys Lipids. 2019 Aug;222:51-58. doi: 10.1016/j.chemphyslip.2019.02.005. Epub 2019 May 15.

PMID:
31102583
12.

The Expectations and Challenges of Wildlife Disease Research in the Era of Genomics: Forecasting with a Horizon Scan-like Exercise.

Fitak RR, Antonides JD, Baitchman EJ, Bonaccorso E, Braun J, Kubiski S, Chiu E, Fagre AC, Gagne RB, Lee JS, Malmberg JL, Stenglein MD, Dusek RJ, Forgacs D, Fountain-Jones NM, Gilbertson MLJ, Worsley-Tonks KEL, Funk WC, Trumbo DR, Ghersi BM, Grimaldi W, Heisel SE, Jardine CM, Kamath PL, Karmacharya D, Kozakiewicz CP, Kraberger S, Loisel DA, McDonald C, Miller S, O'Rourke D, Ott-Conn CN, Páez-Vacas M, Peel AJ, Turner WC, VanAcker MC, VandeWoude S, Pecon-Slattery J.

J Hered. 2019 May 7;110(3):261-274. doi: 10.1093/jhered/esz001.

PMID:
31067326
13.

Vaccination with FAdV-8a induces protection against inclusion body hepatitis caused by homologous and heterologous strains.

Steer-Cope PA, Sandy JR, O'Rourke D, Scott PC, Browning GF, Noormohammadi AH.

Avian Pathol. 2019 Oct;48(5):396-405. doi: 10.1080/03079457.2019.1612032. Epub 2019 Jun 14.

PMID:
31042049
14.

Transcriptome signatures associated with meningioma progression.

Viaene AN, Zhang B, Martinez-Lage M, Xiang C, Tosi U, Thawani JP, Gungor B, Zhu Y, Roccograndi L, Zhang L, Bailey RL, Storm PB, O'Rourke DM, Resnick AC, Grady MS, Dahmane N.

Acta Neuropathol Commun. 2019 Apr 30;7(1):67. doi: 10.1186/s40478-019-0690-x.

15.

A novel CRISPR/Cas9 associated technology for sequence-specific nucleic acid enrichment.

Stevens RC, Steele JL, Glover WR, Sanchez-Garcia JF, Simpson SD, O'Rourke D, Ramsdell JS, MacManes MD, Thomas WK, Shuber AP.

PLoS One. 2019 Apr 18;14(4):e0215441. doi: 10.1371/journal.pone.0215441. eCollection 2019.

16.

Mutation of oppF gene in the Mycoplasma synoviae MS-H vaccine strain and its implication for differential serological responses to vaccination versus field challenge.

Kordafshari S, Marenda MS, O'Rourke D, Shil P, Noormohammadi AH.

Vet Microbiol. 2019 Apr;231:48-55. doi: 10.1016/j.vetmic.2019.02.029. Epub 2019 Feb 22.

PMID:
30955823
17.

LACE+ Index as Predictor of 30-Day Readmission in Brain Tumor Population.

Caplan IF, Sullivan PZ, Kung D, O'Rourke DM, Choudhri O, Glauser G, Osiemo B, Goodrich S, McClintock SD, Malhotra NR.

World Neurosurg. 2019 Jul;127:e443-e448. doi: 10.1016/j.wneu.2019.03.169. Epub 2019 Mar 27.

PMID:
30926557
18.

Ethical and moral considerations of (patient) centredness in nursing and healthcare: Navigating uncharted waters.

O'Rourke DJ, Thompson GN, McMillan DE.

Nurs Inq. 2019 Jul;26(3):e12284. doi: 10.1111/nin.12284. Epub 2019 Mar 27.

PMID:
30916429
19.

Detection of occult neoplastic infiltration in the corpus callosum and prediction of overall survival in patients with glioblastoma using diffusion tensor imaging.

Mohan S, Wang S, Coban G, Kural F, Chawla S, O'Rourke DM, Poptani H.

Eur J Radiol. 2019 Mar;112:106-111. doi: 10.1016/j.ejrad.2019.01.015. Epub 2019 Jan 15.

PMID:
30777198
20.

Influence of stems and metaphyseal sleeve on primary stability of cementless revision tibial trays used to reconstruct AORI IIB defects.

Awadalla M, Al-Dirini RMA, O'Rourke D, Solomon LB, Heldreth M, Rullkoetter P, Taylor M.

J Orthop Res. 2019 May;37(5):1033-1041. doi: 10.1002/jor.24232. Epub 2019 Apr 7.

PMID:
30677164
21.

Molecular analysis of an ancient Thule population at Nuvuk, Point Barrow, Alaska.

Tackney J, Jensen AM, Kisielinski C, O'Rourke DH.

Am J Phys Anthropol. 2019 Feb;168(2):303-317. doi: 10.1002/ajpa.23746.

PMID:
30628076
22.

Investigation onto the correlation between systemic antibodies to surface glycoproteins of infectious laryngotracheitis virus (ILTV) and protective immunity.

Sabir AJ, Adams TE, O'Rourke D, Devlin JM, Noormohammadi AH.

Vet Microbiol. 2019 Jan;228:252-258. doi: 10.1016/j.vetmic.2018.12.010. Epub 2018 Dec 11.

PMID:
30593375
23.

AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival.

Cosimo E, Tarafdar A, Moles MW, Holroyd AK, Malik N, Catherwood MA, Hay J, Dunn KM, Macdonald AM, Guichard SM, O'Rourke D, Leach MT, Sansom OJ, Cosulich SC, McCaig AM, Michie AM.

Clin Cancer Res. 2019 Mar 1;25(5):1574-1587. doi: 10.1158/1078-0432.CCR-18-2036. Epub 2018 Dec 17.

24.

Three-dimensional echo planar spectroscopic imaging for differentiation of true progression from pseudoprogression in patients with glioblastoma.

Verma G, Chawla S, Mohan S, Wang S, Nasrallah M, Sheriff S, Desai A, Brem S, O'Rourke DM, Wolf RL, Maudsley AA, Poptani H.

NMR Biomed. 2019 Feb;32(2):e4042. doi: 10.1002/nbm.4042. Epub 2018 Dec 17.

25.

Relation of Venous Thromboembolism Risk to Ischemic Stroke Risk in Hospitalized Patients with Cancer.

Corley AM, Sullivan MJ, Friedman SE, O'Rourke DJ, Palac RT, Gemignani AS.

Am J Cardiol. 2019 Feb 15;123(4):679-683. doi: 10.1016/j.amjcard.2018.11.008. Epub 2018 Nov 24.

PMID:
30528279
26.

Multiparametric magnetic resonance imaging in the assessment of anti-EGFRvIII chimeric antigen receptor T cell therapy in patients with recurrent glioblastoma.

Wang S, O'Rourke DM, Chawla S, Verma G, Nasrallah MP, Morrissette JJD, Plesa G, June CH, Brem S, Maloney E, Desai A, Wolf RL, Poptani H, Mohan S.

Br J Cancer. 2019 Jan;120(1):54-56. doi: 10.1038/s41416-018-0342-0. Epub 2018 Nov 27.

PMID:
30478409
27.

Virtual trial to evaluate the robustness of cementless femoral stems to patient and surgical variation.

Al-Dirini RMA, Martelli S, O'Rourke D, Huff D, Zhang J, Clement JG, Besier T, Taylor M.

J Biomech. 2019 Jan 3;82:346-356. doi: 10.1016/j.jbiomech.2018.11.013. Epub 2018 Nov 15.

PMID:
30473137
28.

Regulatory and Health Technology Assessment Considerations for Disease-Modifying Drugs in Alzheimer's Disease.

Bouvy JC, Jonsson P, O'Rourke D, Chadha AS, Hedberg N, Makady A, Xoxi E, Wied CG, Schiel A, Long R, Gallacher J.

CNS Drugs. 2018 Dec;32(12):1085-1090. doi: 10.1007/s40263-018-0581-x.

29.

Nontraditional Laboratory Animal Species (Cephalopods, Fish, Amphibians, Reptiles, and Birds).

O'Rourke DP, Baccanale CL, Stoskopf MK.

ILAR J. 2018 Dec 31;59(2):168-176. doi: 10.1093/ilar/ily003.

PMID:
30462255
30.

Histopathologic quantification of viable tumor versus treatment effect in surgically resected recurrent glioblastoma.

Bagley SJ, Schwab RD, Nelson E, Viaene AN, Binder ZA, Lustig RA, O'Rourke DM, Brem S, Desai AS, Nasrallah MP.

J Neurooncol. 2019 Jan;141(2):421-429. doi: 10.1007/s11060-018-03050-6. Epub 2018 Nov 16.

PMID:
30446903
31.

Sampling strategies for approximating patient variability in population-based finite element studies of total hip replacement.

O'Rourke D, Bottema M, Taylor M.

Int J Numer Method Biomed Eng. 2019 Mar;35(3):e3168. doi: 10.1002/cnm.3168. Epub 2018 Nov 18.

PMID:
30394696
32.

New Frontiers in the Treatment of Spinal Muscular Atrophy.

Power CL, O'Rourke DJ.

Ir Med J. 2018 Mar 14;111(3):705. No abstract available.

PMID:
30376223
33.

RNA-seq for identification of therapeutically targetable determinants of immune activation in human glioblastoma.

Bagley SJ, Hwang WT, Brem S, Linette GP, O'Rourke DM, Desai AS.

J Neurooncol. 2019 Jan;141(1):95-102. doi: 10.1007/s11060-018-03010-0. Epub 2018 Oct 23.

PMID:
30353265
34.

Circulating Glioma Cells Exhibit Stem Cell-like Properties.

Liu T, Xu H, Huang M, Ma W, Saxena D, Lustig RA, Alonso-Basanta M, Zhang Z, O'Rourke DM, Zhang L, Gong Y, Kao GD, Dorsey JF, Fan Y.

Cancer Res. 2018 Dec 1;78(23):6632-6642. doi: 10.1158/0008-5472.CAN-18-0650. Epub 2018 Oct 15.

PMID:
30322863
35.

Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas.

Yin Y, Boesteanu AC, Binder ZA, Xu C, Reid RA, Rodriguez JL, Cook DR, Thokala R, Blouch K, McGettigan-Croce B, Zhang L, Konradt C, Cogdill AP, Panjwani MK, Jiang S, Migliorini D, Dahmane N, Posey AD Jr, June CH, Mason NJ, Lin Z, O'Rourke DM, Johnson LA.

Mol Ther Oncolytics. 2018 Aug 28;11:20-38. doi: 10.1016/j.omto.2018.08.002. eCollection 2018 Dec 21.

36.

PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma.

Liu T, Ma W, Xu H, Huang M, Zhang D, He Z, Zhang L, Brem S, O'Rourke DM, Gong Y, Mou Y, Zhang Z, Fan Y.

Nat Commun. 2018 Aug 27;9(1):3439. doi: 10.1038/s41467-018-05982-z.

37.

An early analysis of the cost-effectiveness of a diagnostic classifier for risk stratification of haematuria patients (DCRSHP) compared to flexible cystoscopy in the diagnosis of bladder cancer.

Sutton AJ, Lamont JV, Evans RM, Williamson K, O'Rourke D, Duggan B, Sagoo GS, Reid CN, Ruddock MW.

PLoS One. 2018 Aug 23;13(8):e0202796. doi: 10.1371/journal.pone.0202796. eCollection 2018.

38.

Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.

Binder ZA, Thorne AH, Bakas S, Wileyto EP, Bilello M, Akbari H, Rathore S, Ha SM, Zhang L, Ferguson CJ, Dahiya S, Bi WL, Reardon DA, Idbaih A, Felsberg J, Hentschel B, Weller M, Bagley SJ, Morrissette JJD, Nasrallah MP, Ma J, Zanca C, Scott AM, Orellana L, Davatzikos C, Furnari FB, O'Rourke DM.

Cancer Cell. 2018 Jul 9;34(1):163-177.e7. doi: 10.1016/j.ccell.2018.06.006.

39.

Biomechanical Robustness of a Contemporary Cementless Stem to Surgical Variation in Stem Size and Position.

Al-Dirini RMA, O'Rourke D, Huff D, Martelli S, Taylor M.

J Biomech Eng. 2018 Sep 1;140(9). doi: 10.1115/1.4039824.

PMID:
29801163
40.

Nontraditional Species.

O’Rourke DP, Cox JD, Baumann DP.

In: Weichbrod RH, Thompson GAH, Norton JN, editors. Management of Animal Care and Use Programs in Research, Education, and Testing. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 25.

41.

Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk.

Hlusko LJ, Carlson JP, Chaplin G, Elias SA, Hoffecker JF, Huffman M, Jablonski NG, Monson TA, O'Rourke DH, Pilloud MA, Scott GR.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4426-E4432. doi: 10.1073/pnas.1711788115. Epub 2018 Apr 23.

42.

Differentiation of brain infection from necrotic glioblastoma using combined analysis of diffusion and perfusion MRI.

Chawla S, Wang S, Mohan S, Nasrallah M, Verma G, Brem S, O'Rourke DM, Wolf RL, Poptani H, Nabavizadeh SA.

J Magn Reson Imaging. 2019 Jan;49(1):184-194. doi: 10.1002/jmri.26053. Epub 2018 Apr 20.

PMID:
29676844
43.

Gemcitabine loaded microbubbles for targeted chemo-sonodynamic therapy of pancreatic cancer.

Nesbitt H, Sheng Y, Kamila S, Logan K, Thomas K, Callan B, Taylor MA, Love M, O'Rourke D, Kelly P, Beguin E, Stride E, McHale AP, Callan JF.

J Control Release. 2018 Jun 10;279:8-16. doi: 10.1016/j.jconrel.2018.04.018. Epub 2018 Apr 11.

PMID:
29653222
44.

In vivo evaluation of EGFRvIII mutation in primary glioblastoma patients via complex multiparametric MRI signature.

Akbari H, Bakas S, Pisapia JM, Nasrallah MP, Rozycki M, Martinez-Lage M, Morrissette JJD, Dahmane N, O'Rourke DM, Davatzikos C.

Neuro Oncol. 2018 Jul 5;20(8):1068-1079. doi: 10.1093/neuonc/noy033.

45.

Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1.

Rathore S, Akbari H, Rozycki M, Abdullah KG, Nasrallah MP, Binder ZA, Davuluri RV, Lustig RA, Dahmane N, Bilello M, O'Rourke DM, Davatzikos C.

Sci Rep. 2018 Mar 23;8(1):5087. doi: 10.1038/s41598-018-22739-2.

46.

CAR T-cell therapy for glioblastoma: recent clinical advances and future challenges.

Bagley SJ, Desai AS, Linette GP, June CH, O'Rourke DM.

Neuro Oncol. 2018 Oct 9;20(11):1429-1438. doi: 10.1093/neuonc/noy032.

PMID:
29509936
47.

Treatment outcome of twenty-two patients with guanidinoacetate methyltransferase deficiency: An international retrospective cohort study.

Khaikin Y, Sidky S, Abdenur J, Anastasi A, Ballhausen D, Buoni S, Chan A, Cheillan D, Dorison N, Goldenberg A, Goldstein J, Hofstede FC, Jacquemont ML, Koeberl DD, Lion-Francois L, Lund AM, Mention K, Mundy H, O'Rourke D, Pitelet G, Raspall-Chaure M, Tassini M, Billette de Villemeur T, Williams M, Salomons GS, Mercimek-Andrews S.

Eur J Paediatr Neurol. 2018 May;22(3):369-379. doi: 10.1016/j.ejpn.2018.02.007. Epub 2018 Feb 16.

PMID:
29506905
48.

Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α.

Wang Q, He Z, Huang M, Liu T, Wang Y, Xu H, Duan H, Ma P, Zhang L, Zamvil SS, Hidalgo J, Zhang Z, O'Rourke DM, Dahmane N, Brem S, Mou Y, Gong Y, Fan Y.

Nat Commun. 2018 Feb 8;9(1):559. doi: 10.1038/s41467-018-03050-0.

49.

Chronologic Analysis of Gross and Histologic Lesions Induced by Field Strains of FAdV-1, FAdV-8b, and FAdV-11 in Six-Week-Old Chickens.

Steer-Cope P, Sandy J, O'Rourke D, Scott P, Browning G, Noormohammadi A.

Avian Dis. 2017 Dec;61(4):512-519. doi: 10.1637/11718-072317-Reg.1.

PMID:
29337616
50.

Influence of varying stem and metaphyseal sleeve size on the primary stability of cementless revision tibial trays used to reconstruct AORI IIA defects. A simulation study.

Awadalla M, Al-Dirini RMA, O'Rourke D, Solomon LB, Heldreth M, Taylor M.

J Orthop Res. 2018 Jul;36(7):1876-1886. doi: 10.1002/jor.23851. Epub 2018 Feb 13.

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