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Items: 1 to 50 of 280

1.

Diabetes Increases the Vulnerability of the Cardiac Mitochondrial Network to Criticality.

Vetter L, Cortassa S, O'Rourke B, Armoundas AA, Bedja D, Jende JME, Bendszus M, Paolocci N, Sollot SJ, Aon MA, Kurz FT.

Front Physiol. 2020 Mar 10;11:175. doi: 10.3389/fphys.2020.00175. eCollection 2020.

2.

ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress.

Guo QQ, Wang SS, Zhang SS, Xu HD, Li XM, Guan Y, Yi F, Zhou TT, Jiang B, Bai N, Ma MT, Wang Z, Feng YL, Guo WD, Wu X, Zhao GF, Fan GJ, Zhang SP, Wang CG, Cao LY, O'Rourke BP, Liu SH, Wang PY, Han S, Song XY, Cao L.

EMBO J. 2020 Mar 18:e103111. doi: 10.15252/embj.2019103111. [Epub ahead of print]

PMID:
32187724
3.

Mitochondria Do Not Survive Calcium Overload During Transplantation.

Bertero E, O'Rourke B, Maack C.

Circ Res. 2020 Mar 13;126(6):784-786. doi: 10.1161/CIRCRESAHA.119.316291. Epub 2020 Feb 6. No abstract available.

PMID:
32078444
4.

Does the shoe really fit? Characterising ill-fitting footwear among community-dwelling older adults attending geriatric services: an observational cross-sectional study.

O'Rourke B, Walsh ME, Brophy R, Vallely S, Murphy N, Conroy B, Cunningham C, Horgan NF.

BMC Geriatr. 2020 Feb 13;20(1):55. doi: 10.1186/s12877-020-1448-9.

5.

Osteoarticular Infection in Three Young Thoroughbred Horses Caused by a Novel Gram Negative Cocco-Bacillus.

Hudson BJ, Chicken C, Blishen A, Todhunter KH, Begg AP, Chan L, Karagiannis T, Raymond B, Bogema D, Adkins AR, O'Sullivan CB, O'Rourke BA, Roy Chowdhury P, Djordjevic SP, Charles IG, Edgar A, Mitsakos K.

Case Rep Vet Med. 2020 Jan 19;2020:9785861. doi: 10.1155/2020/9785861. eCollection 2020.

6.

Global knockout of ROMK potassium channel worsens cardiac ischemia-reperfusion injury but cardiomyocyte-specific knockout does not: Implications for the identity of mitoKATP.

Papanicolaou KN, Ashok D, Liu T, Bauer TM, Sun J, Li Z, da Costa E, D'Orleans CC, Nathan S, Lefer DJ, Murphy E, Paolocci N, Foster DB, O'Rourke B.

J Mol Cell Cardiol. 2020 Feb;139:176-189. doi: 10.1016/j.yjmcc.2020.01.010. Epub 2020 Jan 29.

PMID:
32004507
7.

miR-181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart.

Banavath HN, Roman B, Mackowski N, Biswas D, Afzal J, Nomura Y, Solhjoo S, O'Rourke B, Kohr M, Murphy E, Steenbergen C, Das S.

J Am Heart Assoc. 2019 Dec 17;8(24):e012919. doi: 10.1161/JAHA.119.012919. Epub 2019 Dec 5.

8.

The 'Top 10' Challenges for Health Technology Assessment: INAHTA Viewpoint.

O'Rourke B, Werkö SS, Merlin T, Huang LY, Schuller T.

Int J Technol Assess Health Care. 2019 Nov 28:1-4. doi: 10.1017/S0266462319000825. [Epub ahead of print]

PMID:
31775943
9.

Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop

Tian R, Colucci WS, Arany Z, Bachschmid MM, Ballinger SW, Boudina S, Bruce JE, Busija DW, Dikalov S, Dorn GW II, Galis ZS, Gottlieb RA, Kelly DP, Kitsis RN, Kohr MJ, Levy D, Lewandowski ED, McClung JM, Mochly-Rosen D, O'Brien KD, O'Rourke B, Park JY, Ping P, Sack MN, Sheu SS, Shi Y, Shiva S, Wallace DC, Weiss RG, Vernon HJ, Wong R, Schwartz Longacre L.

Circulation. 2019 Oct 1;140(14):1205-1216.

PMID:
31769940
10.

Single-Channel Properties of the ROMK-Pore-Forming Subunit of the Mitochondrial ATP-Sensitive Potassium Channel.

Laskowski M, Augustynek B, Bednarczyk P, Żochowska M, Kalisz J, O'Rourke B, Szewczyk A, Kulawiak B.

Int J Mol Sci. 2019 Oct 25;20(21). pii: E5323. doi: 10.3390/ijms20215323.

11.

Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK.

Wang Y, An H, Liu T, Qin C, Sesaki H, Guo S, Radovick S, Hussain M, Maheshwari A, Wondisford FE, O'Rourke B, He L.

Cell Rep. 2019 Nov 5;29(6):1511-1523.e5. doi: 10.1016/j.celrep.2019.09.070.

12.

Suspected hereditary cervicothoracic vertebral subluxation with cervical myopathy in Poll Merino sheep.

Cronin N, Loukopoulos P, Brown D, O'Rourke BA, Morrice G, Windsor PA.

Aust Vet J. 2019 Dec;97(12):499-504. doi: 10.1111/avj.12877. Epub 2019 Nov 1.

PMID:
31674019
13.

An ABCA12 missense variant in a Shorthorn calf with ichthyosis fetalis.

Woolley SA, Eager KLM, Häfliger IM, Bauer A, Drögemüller C, Leeb T, O'Rourke BA, Tammen I.

Anim Genet. 2019 Dec;50(6):749-752. doi: 10.1111/age.12856. Epub 2019 Sep 30.

PMID:
31568573
14.

Mss51 deletion enhances muscle metabolism and glucose homeostasis in mice.

Rovira Gonzalez YI, Moyer AL, LeTexier NJ, Bratti AD, Feng S, Sun C, Liu T, Mula J, Jha P, Iyer SR, Lovering RM, O'Rourke B, Noh HL, Suk S, Kim JK, Essien Umanah GK, Wagner KR.

JCI Insight. 2019 Oct 17;4(20). pii: 122247. doi: 10.1172/jci.insight.122247.

15.

Precisely Control Mitochondria with Light to Manipulate Cell Fate Decision.

Ernst P, Xu N, Qu J, Chen H, Goldberg MS, Darley-Usmar V, Zhang JJ, O'Rourke B, Liu X, Zhou L.

Biophys J. 2019 Aug 20;117(4):631-645. doi: 10.1016/j.bpj.2019.06.038. Epub 2019 Jul 26.

PMID:
31400914
16.

SIRT1 modulates cell cycle progression by regulating CHK2 acetylation-phosphorylation.

Zhang W, Feng Y, Guo Q, Guo W, Xu H, Li X, Yi F, Guan Y, Geng N, Wang P, Cao L, O'Rourke BP, Jo J, Kwon J, Wang R, Song X, Lee IH, Cao L.

Cell Death Differ. 2020 Feb;27(2):482-496. doi: 10.1038/s41418-019-0369-7. Epub 2019 Jun 17.

PMID:
31209362
17.

Cellular development in muscle differs between Angus steers from low and high muscle score selection lines1.

Greenwood PL, O'Rourke BA, Brunner J, Johns WH, Arthur PF, Cafe LM.

J Anim Sci. 2019 Jul 30;97(8):3199-3212. doi: 10.1093/jas/skz144.

PMID:
31115451
18.

Fidgetin-Like 2 siRNA Enhances the Wound Healing Capability of a Surfactant Polymer Dressing.

O'Rourke BP, Kramer AH, Cao LL, Inayathullah M, Guzik H, Rajadas J, Nosanchuk JD, Sharp DJ.

Adv Wound Care (New Rochelle). 2019 Mar 1;8(3):91-100. doi: 10.1089/wound.2018.0827. Epub 2019 Mar 5.

19.

Building Leadership Capacity for Mission Execution in a Large Academic Department of Medicine.

Golden SH, Bass E, Berry S, Biddison LD, Cayea D, Crews D, Desai S, Ghanem KG, Herzke C, Kirk G, Kisuule F, Levine R, Marr K, O'Rourke B, Pasricha P, Peairs K, Ray S, Durso SC, Hellmann D, Anderson ME.

Am J Med. 2019 Apr;132(4):535-543. doi: 10.1016/j.amjmed.2018.12.003. Epub 2018 Dec 24. No abstract available.

PMID:
30590014
20.

Recognizing that Evidence is Made, not Born.

Lim R, Lee DK, Sabourin P, Ferguson J, Metcalf M, Smith M, Corriol-Rohou S, Eichler HG, Lumpkin M, Hirsch G, Chen IM, O'Rourke B, Schiel A, Crabb N, Aronson N, Pezalla E, Boutin M, Binder L, Wilhelm L.

Clin Pharmacol Ther. 2019 Apr;105(4):844-856. doi: 10.1002/cpt.1317. Epub 2019 Jan 4.

21.

Mitochondrial transplantation in humans: "magical" cure or cause for concern?

Bertero E, Maack C, O'Rourke B.

J Clin Invest. 2018 Dec 3;128(12):5191-5194. doi: 10.1172/JCI124944. Epub 2018 Oct 29. No abstract available.

22.

Atg7 inhibits Warburg effect by suppressing PKM2 phosphorylation resulting reduced epithelial-mesenchymal transition.

Feng Y, Liu J, Guo W, Guan Y, Xu H, Guo Q, Song X, Yi F, Liu T, Zhang W, Dong X, Cao LL, O'Rourke BP, Cao L.

Int J Biol Sci. 2018 May 12;14(7):775-783. doi: 10.7150/ijbs.26077. eCollection 2018.

23.

Mitochondrial ROS Drive Sudden Cardiac Death and Chronic Proteome Remodeling in Heart Failure.

Dey S, DeMazumder D, Sidor A, Foster DB, O'Rourke B.

Circ Res. 2018 Jul 20;123(3):356-371. doi: 10.1161/CIRCRESAHA.118.312708. Epub 2018 Jun 13.

24.

Assessing Spatiotemporal and Functional Organization of Mitochondrial Networks.

Kurz FT, Aon MA, O'Rourke B, Armoundas AA.

Methods Mol Biol. 2018;1782:383-402. doi: 10.1007/978-1-4939-7831-1_23.

25.

An epizootic of Chlamydia psittaci equine reproductive loss associated with suspected spillover from native Australian parrots.

Jenkins C, Jelocnik M, Micallef ML, Galea F, Taylor-Brown A, Bogema DR, Liu M, O'Rourke B, Chicken C, Carrick J, Polkinghorne A.

Emerg Microbes Infect. 2018 May 16;7(1):88. doi: 10.1038/s41426-018-0089-y.

26.

Conservation of cardiac L-type Ca2+ channels and their regulation in Drosophila: A novel genetically-pliable channelopathic model.

Limpitikul WB, Viswanathan MC, O'Rourke B, Yue DT, Cammarato A.

J Mol Cell Cardiol. 2018 Jun;119:64-74. doi: 10.1016/j.yjmcc.2018.04.010. Epub 2018 Apr 21.

27.

Novel organometallic chloroquine derivative inhibits tumor growth.

Hall EA, Ramsey JE, Peng Z, Hayrapetyan D, Shkepu V, O'Rourke B, Geiger W, Lam K, Verschraegen CF.

J Cell Biochem. 2018 Jul;119(7):5921-5933. doi: 10.1002/jcb.26787. Epub 2018 Mar 25.

PMID:
29575007
28.

Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models.

Vakrou S, Fukunaga R, Foster DB, Sorensen L, Liu Y, Guan Y, Woldemichael K, Pineda-Reyes R, Liu T, Tardiff JC, Leinwand LA, Tocchetti CG, Abraham TP, O'Rourke B, Aon MA, Abraham MR.

JCI Insight. 2018 Mar 22;3(6). pii: 94493. doi: 10.1172/jci.insight.94493.

29.

Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation State.

Wang SB, Venkatraman V, Crowgey EL, Liu T, Fu Z, Holewinski R, Ranek M, Kass DA, O'Rourke B, Van Eyk JE.

Circ Res. 2018 May 25;122(11):1517-1531. doi: 10.1161/CIRCRESAHA.118.312789. Epub 2018 Mar 21.

30.

Cardiosphere-Derived Cells Demonstrate Metabolic Flexibility That Is Influenced by Adhesion Status.

Afzal J, Chan A, Karakas MF, Woldemichael K, Vakrou S, Guan Y, Rathmell J, Wahl R, Pomper M, Foster DB, Aon MA, Tsui B, O'Rourke B, Abraham MR.

JACC Basic Transl Sci. 2017 Oct;2(5):543-560. doi: 10.1016/j.jacbts.2017.03.016. Epub 2017 Oct 30.

31.

Effects of Myofascial Trigger Point Release on Power and Force Production in the Lower Limb Kinetic Chain.

Devereux F, OʼRourke B, Byrne PJ, Byrne D, Kinsella S.

J Strength Cond Res. 2019 Sep;33(9):2453-2463. doi: 10.1519/JSC.0000000000002520.

PMID:
29481454
32.

Molecular evidence to suggest pigeon-type Chlamydia psittaci in association with an equine foal loss.

Jelocnik M, Jenkins C, O'Rourke B, Barnwell J, Polkinghorne A.

Transbound Emerg Dis. 2018 Jun;65(3):911-915. doi: 10.1111/tbed.12817. Epub 2018 Jan 19.

PMID:
29352509
33.

Equine chlamydiosis-An emerging infectious disease requiring a one health surveillance approach.

Taylor KA, Durrheim D, Heller J, O'Rourke B, Hope K, Merritt T, Freeman P, Chicken C, Carrick J, Branley J, Massey P.

Zoonoses Public Health. 2018 Feb;65(1):218-221. doi: 10.1111/zph.12391. Epub 2017 Oct 5.

PMID:
28984040
34.

Ichthyosis fetalis in Polled Hereford and Shorthorn calves.

O'Rourke BA, Kelly J, Spiers ZB, Shearer PL, Porter NS, Parma P, Longeri M.

J Vet Diagn Invest. 2017 Nov;29(6):874-876. doi: 10.1177/1040638717724186. Epub 2017 Aug 6.

PMID:
28782451
35.

Functional Implications of Cardiac Mitochondria Clustering.

Kurz FT, Aon MA, O'Rourke B, Armoundas AA.

Adv Exp Med Biol. 2017;982:1-24. doi: 10.1007/978-3-319-55330-6_1. Review.

36.

Myocardial oxidative stress correlates with left ventricular dysfunction on strain echocardiography in a rodent model of sepsis.

Haileselassie B, Su E, Pozios I, Niño DF, Liu H, Lu DY, Ventoulis I, Fulton WB, Sodhi CP, Hackam D, O'Rourke B, Abraham T.

Intensive Care Med Exp. 2017 Dec;5(1):21. doi: 10.1186/s40635-017-0134-5. Epub 2017 Apr 12.

37.

NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer's, and Ethanol Intoxication.

Olszewski RT, Janczura KJ, Bzdega T, Der EK, Venzor F, O'Rourke B, Hark TJ, Craddock KE, Balasubramanian S, Moussa C, Neale JH.

Neurochem Res. 2017 Sep;42(9):2646-2657. doi: 10.1007/s11064-017-2181-4. Epub 2017 Mar 11.

38.

Cdon deficiency causes cardiac remodeling through hyperactivation of WNT/β-catenin signaling.

Jeong MH, Kim HJ, Pyun JH, Choi KS, Lee DI, Solhjoo S, O'Rourke B, Tomaselli GF, Jeong DS, Cho H, Kang JS.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1345-E1354. doi: 10.1073/pnas.1615105114. Epub 2017 Feb 2.

39.

Endovascular therapy using flow diversion for giant internal carotid artery pseudoaneurysm arising in the setting of an invasive pituitary macroadenoma.

Saad AF, Syed A, Marashi KB, O'Rourke BD, Hise JH, Opatowsky MJ, Layton KF.

Proc (Bayl Univ Med Cent). 2017 Jan;30(1):47-49.

40.

Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.

Cho GS, Lee DI, Tampakakis E, Murphy S, Andersen P, Uosaki H, Chelko S, Chakir K, Hong I, Seo K, Chen HV, Chen X, Basso C, Houser SR, Tomaselli GF, O'Rourke B, Judge DP, Kass DA, Kwon C.

Cell Rep. 2017 Jan 10;18(2):571-582. doi: 10.1016/j.celrep.2016.12.040.

41.

Seeing the Forest for the Trees.

O'Rourke B, Liu T, Foster DB.

Circ Res. 2016 Nov 11;119(11):1170-1172. doi: 10.1161/CIRCRESAHA.116.310066. Review. No abstract available.

42.

Control of mitochondrial function and cell growth by the atypical cadherin Fat1.

Cao LL, Riascos-Bernal DF, Chinnasamy P, Dunaway CM, Hou R, Pujato MA, O'Rourke BP, Miskolci V, Guo L, Hodgson L, Fiser A, Sibinga NE.

Nature. 2016 Nov 24;539(7630):575-578. doi: 10.1038/nature20170. Epub 2016 Nov 9.

43.

Promotion and Suppression of Centriole Duplication Are Catalytically Coupled through PLK4 to Ensure Centriole Homeostasis.

Kim M, O'Rourke BP, Soni RK, Jallepalli PV, Hendrickson RC, Tsou MB.

Cell Rep. 2016 Aug 2;16(5):1195-1203. doi: 10.1016/j.celrep.2016.06.069. Epub 2016 Jul 14.

44.

Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death.

Foster DB, Liu T, Kammers K, O'Meally R, Yang N, Papanicolaou KN, Talbot CC Jr, Cole RN, O'Rourke B.

J Proteome Res. 2016 Sep 2;15(9):3009-28. doi: 10.1021/acs.jproteome.6b00149. Epub 2016 Aug 3.

45.

53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis.

Fong CS, Mazo G, Das T, Goodman J, Kim M, O'Rourke BP, Izquierdo D, Tsou MF.

Elife. 2016 Jul 2;5. pii: e16270. doi: 10.7554/eLife.16270.

46.

Metabolism: Beyond the power of mitochondria.

O'Rourke B.

Nat Rev Cardiol. 2016 Jun 15;13(7):386-8. doi: 10.1038/nrcardio.2016.95. No abstract available.

PMID:
27303815
47.

Comparative Proteomics Reveals Dysregulated Mitochondrial O-GlcNAcylation in Diabetic Hearts.

Ma J, Banerjee P, Whelan SA, Liu T, Wei AC, Ramirez-Correa G, McComb ME, Costello CE, O'Rourke B, Murphy A, Hart GW.

J Proteome Res. 2016 Jul 1;15(7):2254-64. doi: 10.1021/acs.jproteome.6b00250. Epub 2016 Jun 2.

PMID:
27213235
48.

Hibernating Squirrels: SIRTin Clues for Organ Protection after Ischemia-Reperfusion.

Berkowitz DE, Steenbergen C, O'Rourke B.

Anesthesiology. 2016 Jun;124(6):1215-7. doi: 10.1097/ALN.0000000000001114. Review. No abstract available.

PMID:
27187117
49.

Compartment-specific Control of Reactive Oxygen Species Scavenging by Antioxidant Pathway Enzymes.

Dey S, Sidor A, O'Rourke B.

J Biol Chem. 2016 May 20;291(21):11185-97. doi: 10.1074/jbc.M116.726968. Epub 2016 Apr 5.

50.

Mitochondrial redox and pH signaling occurs in axonal and synaptic organelle clusters.

Breckwoldt MO, Armoundas AA, Aon MA, Bendszus M, O'Rourke B, Schwarzländer M, Dick TP, Kurz FT.

Sci Rep. 2016 Mar 22;6:23251. doi: 10.1038/srep23251.

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