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Items: 1 to 50 of 114

1.

Resequencing Study Confirms Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis.

Moore C, Blumhagen RZ, Yang IV, Walts A, Powers J, Walker T, Bishop M, Russell P, Vestal B, Cardwell J, Markin CR, Mathai SK, Schwarz MI, Steele MP, Lee J, Brown KK, Loyd JE, Crapo JD, Silverman EK, Cho MH, James JA, Guthridge JM, Cogan JD, Kropski JA, Swigris JJ, Bair C, Soon Kim D, Ji W, Kim H, Song JW, Maier LA, Pacheco KA, Hirani N, Poon AS, Li F, Jenkins RG, Braybrooke R, Saini G, Maher TM, Molyneaux PL, Saunders P, Zhang Y, Gibson KF, Kass DJ, Rojas M, Sembrat J, Wolters PJ, Collard HR, Sundy JS, O'Riordan T, Strek ME, Noth I, Ma SF, Porteous MK, Kreider ME, Patel NB, Inoue Y, Hirose M, Arai T, Akagawa S, Eickelberg O, Fernandez IE, Behr J, Mogulkoc N, Corte TJ, Glaspole I, Tomassetti S, Ravaglia C, Poletti V, Crestani B, Borie R, Kannengiesser C, Parfrey H, Fiddler C, Rassl D, Molina-Molina M, Machahua C, Montes Worboys A, Gudmundsson G, Isaksson HJ, Lederer DJ, Podolanczuk AJ, Montesi SB, Bendstrup E, Danchel V, Selman M, Pardo A, Henry MT, Keane MP, Doran P, Vašáková M, Sterclova M, Ryerson CJ, Wilcox PG, Okamoto T, Furusawa H, Miyazaki Y, Laurent G, Baltic S, Prele C, Moodley Y, Shea BS, Ohta K, Suzukawa M, Narumoto O, Nathan SD, Venuto DC, Woldehanna ML, Kokturk N, de Andrade JA, Luckhardt T, Kulkarni T, Bonella F, Donnelly SC, McElroy A, Armstrong ME, Aranda A, Carbone RG, Puppo F, Beckman KB, Nickerson DA, Fingerlin TE, Schwartz DA.

Am J Respir Crit Care Med. 2019 Apr 29. doi: 10.1164/rccm.201810-1891OC. [Epub ahead of print]

2.

Supporting informed choice in acupuncture: effects of a new person-, evidence- and theory-based website for patients with back pain.

Bishop FL, Greville-Harris M, Bostock J, Din A, Graham CA, Lewith G, Liossi C, O'Riordan T, White P, Yardley L.

Acupunct Med. 2019 Apr;37(2):98-106. doi: 10.1177/0964528419827228. Epub 2019 Mar 21.

PMID:
30896248
3.

Informing Adults With Back Pain About Placebo Effects: Randomized Controlled Evaluation of a New Website With Potential to Improve Informed Consent in Clinical Research.

Bishop FL, Greville-Harris M, Bostock J, Din A, Graham CA, Lewith G, Liossi C, O'Riordan T, White P, Yardley L.

J Med Internet Res. 2019 Jan 17;21(1):e9955. doi: 10.2196/jmir.9955.

4.

Quantitative high-resolution computed tomography fibrosis score: performance characteristics in idiopathic pulmonary fibrosis.

Humphries SM, Swigris JJ, Brown KK, Strand M, Gong Q, Sundy JS, Raghu G, Schwarz MI, Flaherty KR, Sood R, O'Riordan TG, Lynch DA.

Eur Respir J. 2018 Sep 17;52(3). pii: 1801384. doi: 10.1183/13993003.01384-2018. Print 2018 Sep.

PMID:
30139770
5.

Deferred diagnosis in children assessed for fetal alcohol spectrum disorder.

Flannigan K, Gill K, Pei J, Andrew G, Rajani H, McFarlane A, O'Riordan T, Symes B, Rasmussen C.

Appl Neuropsychol Child. 2018 Feb 12:1-10. doi: 10.1080/21622965.2018.1427094. [Epub ahead of print]

PMID:
29432031
6.

Using hyperpolarized 129Xe MRI to quantify regional gas transfer in idiopathic pulmonary fibrosis.

Wang JM, Robertson SH, Wang Z, He M, Virgincar RS, Schrank GM, Smigla RM, O'Riordan TG, Sundy J, Ebner L, Rackley CR, McAdams P, Driehuys B.

Thorax. 2018 Jan;73(1):21-28. doi: 10.1136/thoraxjnl-2017-210070. Epub 2017 Aug 31.

7.

The importance of an integrating framework for achieving the Sustainable Development Goals: the example of health and well-being.

Nunes AR, Lee K, O'Riordan T.

BMJ Glob Health. 2016 Nov 24;1(3):e000068. doi: 10.1136/bmjgh-2016-000068. eCollection 2016.

8.

Quantitative analysis of hyperpolarized 129 Xe gas transfer MRI.

Wang Z, Robertson SH, Wang J, He M, Virgincar RS, Schrank GM, Bier EA, Rajagopal S, Huang YC, O'Riordan TG, Rackley CR, McAdams HP, Driehuys B.

Med Phys. 2017 Jun;44(6):2415-2428. doi: 10.1002/mp.12264. Epub 2017 May 18.

PMID:
28382694
9.

An Exome Sequencing Study to Assess the Role of Rare Genetic Variation in Pulmonary Fibrosis.

Petrovski S, Todd JL, Durheim MT, Wang Q, Chien JW, Kelly FL, Frankel C, Mebane CM, Ren Z, Bridgers J, Urban TJ, Malone CD, Finlen Copeland A, Brinkley C, Allen AS, O'Riordan T, McHutchison JG, Palmer SM, Goldstein DB.

Am J Respir Crit Care Med. 2017 Jul 1;196(1):82-93. doi: 10.1164/rccm.201610-2088OC.

10.

Research priorities for managing the impacts and dependencies of business upon food, energy, water and the environment.

Green JMH, Cranston GR, Sutherland WJ, Tranter HR, Bell SJ, Benton TG, Blixt E, Bowe C, Broadley S, Brown A, Brown C, Burns N, Butler D, Collins H, Crowley H, DeKoszmovszky J, Firbank LG, Fulford B, Gardner TA, Hails RS, Halvorson S, Jack M, Kerrison B, Koh LSC, Lang SC, McKenzie EJ, Monsivais P, O'Riordan T, Osborn J, Oswald S, Price Thomas E, Raffaelli D, Reyers B, Srai JS, Strassburg BBN, Webster D, Welters R, Whiteman G, Wilsdon J, Vira B.

Sustain Sci. 2017;12(2):319-331. doi: 10.1007/s11625-016-0402-4. Epub 2016 Oct 7.

11.

Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial.

Raghu G, Brown KK, Collard HR, Cottin V, Gibson KF, Kaner RJ, Lederer DJ, Martinez FJ, Noble PW, Song JW, Wells AU, Whelan TP, Wuyts W, Moreau E, Patterson SD, Smith V, Bayly S, Chien JW, Gong Q, Zhang JJ, O'Riordan TG.

Lancet Respir Med. 2017 Jan;5(1):22-32. doi: 10.1016/S2213-2600(16)30421-0. Epub 2016 Dec 7.

PMID:
27939076
12.

Using psychological theory and qualitative methods to develop a new evidence-based website about acupuncture for back pain.

Bishop FL, Greville-Harris M, Bostock J, Din A, Graham CA, Lewith G, Liossi C, O'Riordan T, Ryves R, White P, Yardley L.

Eur J Integr Med. 2016 Aug;8(4):384-393.

13.

Synthesis and evaluation of hydroxyazolopyrimidines as herbicides; the generation of amitrole in planta.

Clough JM, Dale RP, Elsdon B, Hawkes TR, Hogg BV, Howell A, Kloer DP, Lecoq K, McLachlan MM, Milnes PJ, O'Riordan TJ, Ranasinghe S, Shanahan SE, Sumner KD, Tayab S.

Pest Manag Sci. 2016 Dec;72(12):2254-2272. doi: 10.1002/ps.4264. Epub 2016 Apr 4.

PMID:
26918632
14.

Enantioselective isothiourea-catalysed trans-dihydropyridinone synthesis using saccharin-derived ketimines: scope and limitations.

Stark DG, Young CM, O'Riordan TJ, Slawin AM, Smith AD.

Org Biomol Chem. 2016 Sep 14;14(34):8068-73. doi: 10.1039/c6ob01473a. Epub 2016 Aug 5.

PMID:
27492887
15.

Isothiourea-catalysed enantioselective pyrrolizine synthesis: synthetic and computational studies.

Stark DG, Williamson P, Gayner ER, Musolino SF, Kerr RW, Taylor JE, Slawin AM, O'Riordan TJ, Macgregor SA, Smith AD.

Org Biomol Chem. 2016 Oct 14;14(38):8957-65. doi: 10.1039/c6ob01557c. Epub 2016 Aug 4.

16.

Informing Patients About Placebo Effects: Using Evidence, Theory, and Qualitative Methods to Develop a New Website.

Greville-Harris M, Bostock J, Din A, Graham CA, Lewith G, Liossi C, O'Riordan T, White P, Yardley L, Bishop FL.

JMIR Res Protoc. 2016 Jun 10;5(2):e106. doi: 10.2196/resprot.5627.

17.

Enantioselective Synthesis of 3,5,6-Substituted Dihydropyranones and Dihydropyridinones using Isothiourea-Mediated Catalysis.

Stark DG, Morrill LC, Cordes DB, Slawin AM, O'Riordan TJ, Smith AD.

Chem Asian J. 2016 Feb 4;11(3):395-400. doi: 10.1002/asia.201500907. Epub 2015 Nov 12.

18.

Thiazolidinediones are associated with a reduced risk of COPD exacerbations.

Rinne ST, Liu CF, Feemster LC, Collins BF, Bryson CL, O'Riordan TG, Au DH.

Int J Chron Obstruct Pulmon Dis. 2015 Aug 10;10:1591-7. doi: 10.2147/COPD.S82643. eCollection 2015.

19.

Pulmonary hypertension in idiopathic pulmonary fibrosis with mild-to-moderate restriction.

Raghu G, Nathan SD, Behr J, Brown KK, Egan JJ, Kawut SM, Flaherty KR, Martinez FJ, Wells AU, Shao L, Zhou H, Henig N, Szwarcberg J, Gillies H, Montgomery AB, O'Riordan TG.

Eur Respir J. 2015 Nov;46(5):1370-7. doi: 10.1183/13993003.01537-2014. Epub 2015 Aug 6.

20.

Development of novel agents for idiopathic pulmonary fibrosis: progress in target selection and clinical trial design.

O'Riordan TG, Smith V, Raghu G.

Chest. 2015 Oct;148(4):1083-1092. doi: 10.1378/chest.14-3218. Review.

PMID:
26020856
21.

Rational Drug Development for Mucous Dehydration and Mucous Metaplasia.

O'Riordan TG.

J Aerosol Med Pulm Drug Deliv. 2016 Feb;29(1):1-9. doi: 10.1089/jamp.2014.1190. Epub 2015 May 14.

PMID:
25974653
22.

Duration of action of hypertonic saline on mucociliary clearance in the normal lung.

Bennett WD, Wu J, Fuller F, Balcazar JR, Zeman KL, Duckworth H, Donn KH, O'Riordan TG, Boucher RC, Donaldson SH.

J Appl Physiol (1985). 2015 Jun 15;118(12):1483-90. doi: 10.1152/japplphysiol.00404.2014. Epub 2015 Apr 24.

23.

Synthesis of di-, tri-, and tetrasubstituted pyridines from (phenylthio)carboxylic acids and 2-[aryl(tosylimino)methyl]acrylates.

Stark DG, O'Riordan TJ, Smith AD.

Org Lett. 2014 Dec 19;16(24):6496-9. doi: 10.1021/ol503360q. Epub 2014 Dec 8.

PMID:
25484189
24.

Quality of Life Questionnaire-Bronchiectasis: final psychometric analyses and determination of minimal important difference scores.

Quittner AL, O'Donnell AE, Salathe MA, Lewis SA, Li X, Montgomery AB, O'Riordan TG, Barker AF.

Thorax. 2015 Jan;70(1):12-20. doi: 10.1136/thoraxjnl-2014-205918. Epub 2014 Oct 16.

PMID:
25323621
25.

Organocatalytic Michael addition-lactonisation of carboxylic acids using α,β-unsaturated trichloromethyl ketones as α,β-unsaturated ester equivalents.

Morrill LC, Stark DG, Taylor JE, Smith SR, Squires JA, D'Hollander AC, Simal C, Shapland P, O'Riordan TJ, Smith AD.

Org Biomol Chem. 2014 Nov 28;12(44):9016-27. doi: 10.1039/c4ob01788a.

PMID:
25285662
26.

Aztreonam for inhalation solution in patients with non-cystic fibrosis bronchiectasis (AIR-BX1 and AIR-BX2): two randomised double-blind, placebo-controlled phase 3 trials.

Barker AF, O'Donnell AE, Flume P, Thompson PJ, Ruzi JD, de Gracia J, Boersma WG, De Soyza A, Shao L, Zhang J, Haas L, Lewis SA, Leitzinger S, Montgomery AB, McKevitt MT, Gossage D, Quittner AL, O'Riordan TG.

Lancet Respir Med. 2014 Sep;2(9):738-49. doi: 10.1016/S2213-2600(14)70165-1. Epub 2014 Aug 18.

PMID:
25154045
27.

Oral GS-5806 activity in a respiratory syncytial virus challenge study.

DeVincenzo JP, Whitley RJ, Mackman RL, Scaglioni-Weinlich C, Harrison L, Farrell E, McBride S, Lambkin-Williams R, Jordan R, Xin Y, Ramanathan S, O'Riordan T, Lewis SA, Li X, Toback SL, Lin SL, Chien JW.

N Engl J Med. 2014 Aug 21;371(8):711-22. doi: 10.1056/NEJMoa1401184.

28.

Thiazolidinediones and the risk of asthma exacerbation among patients with diabetes: a cohort study.

Rinne ST, Feemster LC, Collins BF, Au DH, Perkins M, Bryson CL, O'Riordan TG, Liu CF.

Allergy Asthma Clin Immunol. 2014 Jul 3;10(1):34. doi: 10.1186/1710-1492-10-34. eCollection 2014.

29.

Diagnosis of idiopathic pulmonary fibrosis with high-resolution CT--authors' reply.

Raghu G, O'Riordan TG.

Lancet Respir Med. 2014 May;2(5):e5-6. doi: 10.1016/S2213-2600(14)70098-0. No abstract available.

PMID:
24815807
30.

Diagnosis of idiopathic pulmonary fibrosis with high-resolution CT in patients with little or no radiological evidence of honeycombing: secondary analysis of a randomised, controlled trial.

Raghu G, Lynch D, Godwin JD, Webb R, Colby TV, Leslie KO, Behr J, Brown KK, Egan JJ, Flaherty KR, Martinez FJ, Wells AU, Shao L, Zhou H, Pedersen PS, Sood R, Montgomery AB, O'Riordan TG.

Lancet Respir Med. 2014 Apr;2(4):277-84. doi: 10.1016/S2213-2600(14)70011-6. Epub 2014 Feb 18.

PMID:
24717624
31.

A preliminary quality of life questionnaire-bronchiectasis: a patient-reported outcome measure for bronchiectasis.

Quittner AL, Marciel KK, Salathe MA, O'Donnell AE, Gotfried MH, Ilowite JS, Metersky ML, Flume PA, Lewis SA, McKevitt M, Montgomery AB, O'Riordan TG, Barker AF.

Chest. 2014 Aug;146(2):437-448. doi: 10.1378/chest.13-1891. Review. Erratum in: Chest. 2014 Nov;146(5):1422.

PMID:
24626872
32.

Serum lysyl oxidase-like 2 levels and idiopathic pulmonary fibrosis disease progression.

Chien JW, Richards TJ, Gibson KF, Zhang Y, Lindell KO, Shao L, Lyman SK, Adamkewicz JI, Smith V, Kaminski N, O'Riordan T.

Eur Respir J. 2014 May;43(5):1430-8. doi: 10.1183/09031936.00141013. Epub 2013 Oct 31.

33.

Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.

Blackwell TS, Tager AM, Borok Z, Moore BB, Schwartz DA, Anstrom KJ, Bar-Joseph Z, Bitterman P, Blackburn MR, Bradford W, Brown KK, Chapman HA, Collard HR, Cosgrove GP, Deterding R, Doyle R, Flaherty KR, Garcia CK, Hagood JS, Henke CA, Herzog E, Hogaboam CM, Horowitz JC, King TE Jr, Loyd JE, Lawson WE, Marsh CB, Noble PW, Noth I, Sheppard D, Olsson J, Ortiz LA, O'Riordan TG, Oury TD, Raghu G, Roman J, Sime PJ, Sisson TH, Tschumperlin D, Violette SM, Weaver TE, Wells RG, White ES, Kaminski N, Martinez FJ, Wynn TA, Thannickal VJ, Eu JP.

Am J Respir Crit Care Med. 2014 Jan 15;189(2):214-22. doi: 10.1164/rccm.201306-1141WS.

34.

Isothiourea-mediated one-pot synthesis of functionalized pyridines.

Stark DG, Morrill LC, Yeh PP, Slawin AM, O'Riordan TJ, Smith AD.

Angew Chem Int Ed Engl. 2013 Oct 25;52(44):11642-6. doi: 10.1002/anie.201306786. Epub 2013 Sep 17.

35.

Airway drug pharmacokinetics via analysis of exhaled breath condensate.

Esther CR Jr, Boucher RC, Johnson MR, Ansede JH, Donn KH, O'Riordan TG, Ghio AJ, Hirsh AJ.

Pulm Pharmacol Ther. 2014 Feb;27(1):76-82. doi: 10.1016/j.pupt.2013.07.009. Epub 2013 Aug 7.

36.

Acute hyperkalemia associated with inhalation of a potent ENaC antagonist: Phase 1 trial of GS-9411.

O'Riordan TG, Donn KH, Hodsman P, Ansede JH, Newcomb T, Lewis SA, Flitter WD, White VS, Johnson MR, Montgomery AB, Warnock DG, Boucher RC.

J Aerosol Med Pulm Drug Deliv. 2014 Jun;27(3):200-8. doi: 10.1089/jamp.2013.1037. Epub 2013 Aug 1.

PMID:
23905576
37.

Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial.

Raghu G, Behr J, Brown KK, Egan JJ, Kawut SM, Flaherty KR, Martinez FJ, Nathan SD, Wells AU, Collard HR, Costabel U, Richeldi L, de Andrade J, Khalil N, Morrison LD, Lederer DJ, Shao L, Li X, Pedersen PS, Montgomery AB, Chien JW, O'Riordan TG; ARTEMIS-IPF Investigators*.

Ann Intern Med. 2013 May 7;158(9):641-9. doi: 10.7326/0003-4819-158-9-201305070-00003. Erratum in: Ann Intern Med. 2014 May 6;160(9):658.

PMID:
23648946
38.

Differences in prevalence of geohelminth infections between indigenous and settler populations in a remote Amazonian region of Peru.

Briones-Chávez C, Torres-Zevallos H, Canales M, Stamato CM, O'Riordan TG, Terashima A.

Trop Med Int Health. 2013 May;18(5):615-8. doi: 10.1111/tmi.12077. Epub 2013 Feb 14.

39.

Asymmetric synthesis of the fully elaborated pyrrolidinone core of oxazolomycin A.

Donohoe TJ, O'Riordan TJ, Peifer M, Jones CR, Miles TJ.

Org Lett. 2012 Nov 2;14(21):5460-3. doi: 10.1021/ol302541j. Epub 2012 Oct 12.

PMID:
23061613
40.

Disulphide bond reduction of a therapeutic monoclonal antibody during cell culture manufacturing operations.

Mullan B, Dravis B, Lim A, Clarke A, Janes S, Lambooy P, Olson D, O'Riordan T, Ricart B, Tulloch AG.

BMC Proc. 2011 Nov 22;5 Suppl 8:P110. doi: 10.1186/1753-6561-5-S8-P110. eCollection 2011. No abstract available.

41.

Mitochondrial respiration protects against oxygen-associated DNA damage.

Sung HJ, Ma W, Wang PY, Hynes J, O'Riordan TC, Combs CA, McCoy JP Jr, Bunz F, Kang JG, Hwang PM.

Nat Commun. 2010 Apr 12;1:5. doi: 10.1038/ncomms1003.

42.

Imaging of cellular oxygen and analysis of metabolic responses of mammalian cells.

Fercher A, O'Riordan TC, Zhdanov AV, Dmitriev RI, Papkovsky DB.

Methods Mol Biol. 2010;591:257-73. doi: 10.1007/978-1-60761-404-3_16.

PMID:
19957136
43.

In vitro analysis of cell metabolism using a long-decay pH-sensitive lanthanide probe and extracellular acidification assay.

Hynes J, O'Riordan TC, Zhdanov AV, Uray G, Will Y, Papkovsky DB.

Anal Biochem. 2009 Jul 1;390(1):21-8. doi: 10.1016/j.ab.2009.04.016. Epub 2009 Apr 18.

PMID:
19379702
44.

Ruthenium-catalyzed isomerization of terminal olefins: applications to synthesis.

Donohoe TJ, O'Riordan TJ, Rosa CP.

Angew Chem Int Ed Engl. 2009;48(6):1014-7. doi: 10.1002/anie.200804617. No abstract available.

PMID:
19130520
45.

Synthesis of (+)-DGDP and (-)-7-epialexine.

Donohoe TJ, Cheeseman MD, O'Riordan TJ, Kershaw JA.

Org Biomol Chem. 2008 Nov 7;6(21):3896-8. doi: 10.1039/b815332a. Epub 2008 Sep 19.

PMID:
18931792
46.

Aerosolized antibiotics and ventilator-associated tracheobronchitis in the intensive care unit.

Palmer LB, Smaldone GC, Chen JJ, Baram D, Duan T, Monteforte M, Varela M, Tempone AK, O'Riordan T, Daroowalla F, Richman P.

Crit Care Med. 2008 Jul;36(7):2008-13. doi: 10.1097/CCM.0b013e31817c0f9e.

PMID:
18552684
47.

Analysis of intracellular oxygen and metabolic responses of mammalian cells by time-resolved fluorometry.

O'Riordan TC, Zhdanov AV, Ponomarev GV, Papkovsky DB.

Anal Chem. 2007 Dec 15;79(24):9414-9. Epub 2007 Nov 15.

PMID:
18001129
48.

Aerosolized iloprost customized for the critically ill.

Harris KW, O'Riordan TG, Smaldone GC.

Respir Care. 2007 Nov;52(11):1507-9.

49.

Homogeneous time-resolved fluorescence assays for the detection of activity and inhibition of phosphatase enzymes employing phosphorescently labeled peptide substrates.

O'Shea DJ, O'Riordan TC, O'Sullivan PJ, Papkovsky DB.

Anal Chim Acta. 2007 Feb 5;583(2):349-56. Epub 2006 Oct 21.

PMID:
17386566
50.

Quantitative detection of cell surface protein expression by time-resolved fluorimetry.

Huttunen RJ, O'Riordan TC, Härkönen PL, Soini JT, Meltola NJ, Hänninen PE, Soini AE.

Luminescence. 2007 May-Jun;22(3):163-70.

PMID:
17262721

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