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Items: 1 to 50 of 385

1.

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.

Coleman JRI, Peyrot WJ, Purves KL, Davis KAS, Rayner C, Choi SW, Hübel C, Gaspar HA, Kan C, Van der Auwera S, Adams MJ, Lyall DM, Choi KW; on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dunn EC, Vassos E, Danese A, Maughan B, Grabe HJ, Lewis CM, O'Reilly PF, McIntosh AM, Smith DJ, Wray NR, Hotopf M, Eley TC, Breen G.

Mol Psychiatry. 2020 Jan 23. doi: 10.1038/s41380-019-0546-6. [Epub ahead of print]

PMID:
31969693
2.

Pathways, Processes, and Candidate Drugs Associated with a Hoxa Cluster-Dependency Model of Leukemia.

Kettyle LM, Lebert-Ghali CÉ, Grishagin IV, Dickson GJ, O'Reilly PG, Simpson DA, Bijl JJ, Mills KI, Sauvageau G, Thompson A.

Cancers (Basel). 2019 Dec 17;11(12). pii: E2036. doi: 10.3390/cancers11122036.

3.

Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent.

Hübel C, Gaspar HA, Coleman JRI, Hanscombe KB, Purves K, Prokopenko I, Graff M, Ngwa JS, Workalemahu T; ADHD Working Group of the Psychiatric Genomics Consortium; Meta-Analyses of Glucose and Insulin-related traits consortium (MAGIC); Autism Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Eating Disorders Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium; PTSD Working Group of the Psychiatric Genomics Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Sex Differences Cross Disorder Working Group of the Psychiatric Genomics Consortium; Substance Use Disorders Working Group of the Psychiatric Genomics Consortium; German Borderline Genomics Consortium; International Headache Genetics Consortium, O'Reilly PF, Bulik CM, Breen G.

Nat Commun. 2019 Dec 18;10(1):5765. doi: 10.1038/s41467-019-13544-0.

4.

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI.

Couto Alves A, De Silva NMG, Karhunen V, Sovio U, Das S, Taal HR, Warrington NM, Lewin AM, Kaakinen M, Cousminer DL, Thiering E, Timpson NJ, Bond TA, Lowry E, Brown CD, Estivill X, Lindi V, Bradfield JP, Geller F, Speed D, Coin LJM, Loh M, Barton SJ, Beilin LJ, Bisgaard H, Bønnelykke K, Alili R, Hatoum IJ, Schramm K, Cartwright R, Charles MA, Salerno V, Clément K, Claringbould AAJ; BIOS Consortium, van Duijn CM, Moltchanova E, Eriksson JG, Elks C, Feenstra B, Flexeder C, Franks S, Frayling TM, Freathy RM, Elliott P, Widén E, Hakonarson H, Hattersley AT, Rodriguez A, Banterle M, Heinrich J, Heude B, Holloway JW, Hofman A, Hyppönen E, Inskip H, Kaplan LM, Hedman AK, Läärä E, Prokisch H, Grallert H, Lakka TA, Lawlor DA, Melbye M, Ahluwalia TS, Marinelli M, Millwood IY, Palmer LJ, Pennell CE, Perry JR, Ring SM, Savolainen MJ, Rivadeneira F, Standl M, Sunyer J, Tiesler CMT, Uitterlinden AG, Schierding W, O'Sullivan JM, Prokopenko I, Herzig KH, Smith GD, O'Reilly P, Felix JF, Buxton JL, Blakemore AIF, Ong KK, Jaddoe VWV, Grant SFA, Sebert S, McCarthy MI, Järvelin MR; Early Growth Genetics (EGG) Consortium.

Sci Adv. 2019 Sep 4;5(9):eaaw3095. doi: 10.1126/sciadv.aaw3095. eCollection 2019 Sep.

5.

Cannabis use, depression and self-harm: phenotypic and genetic relationships.

Hodgson K, Coleman JRI, Hagenaars SP, Purves KL, Glanville K, Choi SW, O'Reilly P, Breen G; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Lewis CM.

Addiction. 2019 Dec 12. doi: 10.1111/add.14845. [Epub ahead of print]

PMID:
31833150
6.

The psychological impact of Stevens-Johnson syndrome and toxic epidermal necrolysis on patients' lives: a Critically Appraised Topic.

O'Reilly P, Kennedy C, Meskell P, Coffey A, Delaunois I, Dore L, Howard S, Ramsay B, Scanlon C, Wilson DM, Whelan B, Ryan S.

Br J Dermatol. 2019 Dec 2. doi: 10.1111/bjd.18746. [Epub ahead of print]

PMID:
31792924
7.

Translational AI and Deep Learning in Diagnostic Pathology.

Serag A, Ion-Margineanu A, Qureshi H, McMillan R, Saint Martin MJ, Diamond J, O'Reilly P, Hamilton P.

Front Med (Lausanne). 2019 Oct 1;6:185. doi: 10.3389/fmed.2019.00185. eCollection 2019. Review.

8.

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression.

Glanville KP, Coleman JRI, Hanscombe KB, Euesden J, Choi SW, Purves KL, Breen G, Air TM, Andlauer TFM, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, Buttenschøn HN, Colodro-Conde L, Dannlowski U, Direk N, Dunn EC, Forstner AJ, de Geus EJC, Grabe HJ, Hamilton SP, Jones I, Jones LA, Knowles JA, Kutalik Z, Levinson DF, Lewis G, Lind PA, Lucae S, Magnusson PK, McGuffin P, McIntosh AM, Milaneschi Y, Mors O, Mostafavi S, Müller-Myhsok B, Pedersen NL, Penninx BWJH, Potash JB, Preisig M, Ripke S, Shi J, Shyn SI, Smoller JW, Streit F, Sullivan PF, Tiemeier H, Uher R, Van der Auwera S, Weissman MM; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, O'Reilly PF, Lewis CM.

Biol Psychiatry. 2019 Aug 5. pii: S0006-3223(19)31558-6. doi: 10.1016/j.biopsych.2019.06.031. [Epub ahead of print]

9.

Evolutionary and functional impact of common polymorphic inversions in the human genome.

Giner-Delgado C, Villatoro S, Lerga-Jaso J, Gayà-Vidal M, Oliva M, Castellano D, Pantano L, Bitarello BD, Izquierdo D, Noguera I, Olalde I, Delprat A, Blancher A, Lalueza-Fox C, Esko T, O'Reilly PF, Andrés AM, Ferretti L, Puig M, Cáceres M.

Nat Commun. 2019 Sep 17;10(1):4222. doi: 10.1038/s41467-019-12173-x.

10.

Body composition in anorexia nervosa: Meta-analysis and meta-regression of cross-sectional and longitudinal studies.

Hübel C, Yilmaz Z, Schaumberg KE, Breithaupt L, Hunjan A, Horne E, García-González J, O'Reilly PF, Bulik CM, Breen G.

Int J Eat Disord. 2019 Nov;52(11):1205-1223. doi: 10.1002/eat.23158. Epub 2019 Sep 12. Review.

11.

Defining the molecular evolution of extrauterine high grade serous carcinoma.

Beirne JP, McArt DG, Roddy A, McDermott C, Ferris J, Buckley NE, Coulter P, McCabe N, Eddie SL, Dunne PD, O'Reilly P, Gilmore A, Feeney L, Ewing DL, Drapkin RI, Salto-Tellez M, Kennedy RD, Harley IJG, McCluggage WG, Mullan PB.

Gynecol Oncol. 2019 Nov;155(2):305-317. doi: 10.1016/j.ygyno.2019.08.029. Epub 2019 Sep 4.

PMID:
31493898
12.

NUQA: Estimating Cancer Spatial and Temporal Heterogeneity and Evolution through Alignment-Free Methods.

Roddy AC, Jurek-Loughrey A, Souza J, Gilmore A, O'Reilly PG, Stupnikov A, Gonzalez de Castro D, Prise KM, Salto-Tellez M, McArt DG.

Mol Biol Evol. 2019 Dec 1;36(12):2883-2889. doi: 10.1093/molbev/msz182.

13.

Bereavement Counselling for Healthcare Workers in the Aftermath of Child Death

O’Sullivan D, Stone G, Mahomed H, O’Reilly P, Stewart P, Noonan H, Murphy AM.

Ir Med J. 2019 May 9;112(5):931. No abstract available.

PMID:
31411013
14.

Key stakeholders' perspectives on the development of a national transfer document, for older persons, when transferring between the residential and acute care settings: A qualitative descriptive study.

O'Reilly P, O'Brien B, Graham MM, Murphy J, Barry L, Doody O, Fahy A, Hoey C, Kiely M, Lang D, Meskell P, O'Doherty J, O'Keefe J, Tuohy D, Coffey A.

Int J Older People Nurs. 2019 Dec;14(4):e12254. doi: 10.1111/opn.12254. Epub 2019 Jul 26.

15.

PRSice-2: Polygenic Risk Score software for biobank-scale data.

Choi SW, O'Reilly PF.

Gigascience. 2019 Jul 1;8(7). pii: giz082. doi: 10.1093/gigascience/giz082.

16.

Comparing Within- and Between-Family Polygenic Score Prediction.

Selzam S, Ritchie SJ, Pingault JB, Reynolds CA, O'Reilly PF, Plomin R.

Am J Hum Genet. 2019 Aug 1;105(2):351-363. doi: 10.1016/j.ajhg.2019.06.006. Epub 2019 Jul 11.

17.

Integrative review; identifying the evidence base for policymaking and analysis in health care.

Kennedy C, O'Reilly P, O'Connell R, O'Leary D, Fealy G, Hegarty JM, Brady AM, Nicholson E, McNamara M, Casey M.

J Adv Nurs. 2019 Dec;75(12):3231-3245. doi: 10.1111/jan.14121. Epub 2019 Jul 31. Review.

PMID:
31222800
18.

Developing a new health-related policy analysis tool: An action research cooperative inquiry approach.

Casey M, Rohde D, Brady AM, Fealy G, Hegarty J, Kennedy C, McNamara M, Nicholson E, O'Connell R, O'Connor L, O'Leary D, O'Reilly P, Stokes D.

J Nurs Manag. 2019 Sep;27(6):1233-1241. doi: 10.1111/jonm.12804. Epub 2019 Jun 27.

PMID:
31169959
19.

Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts.

Bond TA, Karhunen V, Wielscher M, Auvinen J, Männikkö M, Keinänen-Kiukaanniemi S, Gunter MJ, Felix JF, Prokopenko I, Yang J, Visscher PM, Evans DM, Sebert S, Lewin A, O'Reilly PF, Lawlor DA, Jarvelin MR.

Int J Epidemiol. 2019 May 10. pii: dyz095. doi: 10.1093/ije/dyz095. [Epub ahead of print]

20.

Profiling emergency department presentations of 14-15-year-olds in modern Ireland.

Martin T, Corcoran A, Canty N, Dillon J, O'Reilly P, O'Donnell G, Twomey J, Murphy AM.

Ir J Med Sci. 2019 Nov;188(4):1407-1411. doi: 10.1007/s11845-019-02002-x. Epub 2019 Mar 12.

PMID:
30864009
21.

ACE: A Workbench Using Evolutionary Genetic Algorithms for Analyzing Association in TCGA.

Gilmore AR, Alderdice M, Savage KI, O'Reilly PG, Roddy AC, Dunne PD, Lawler M, McDade SS, Waugh DJ, McArt DG.

Cancer Res. 2019 Apr 15;79(8):2072-2075. doi: 10.1158/0008-5472.CAN-18-1976. Epub 2019 Feb 13.

PMID:
30760519
22.

Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.

Hübel C, Gaspar HA, Coleman JRI, Finucane H, Purves KL, Hanscombe KB, Prokopenko I; MAGIC investigators, Graff M, Ngwa JS, Workalemahu T; Eating Disorders Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Tourette Syndrome/Obsessive-Compulsive Disorder Working Group of the Psychiatric Genomics Consortium, O'Reilly PF, Bulik CM, Breen G.

Am J Med Genet B Neuropsychiatr Genet. 2019 Sep;180(6):428-438. doi: 10.1002/ajmg.b.32709. Epub 2018 Dec 28.

23.

Coming of Age in Ireland: the Twilight Zone!

Power BD, Stewart P, Stone G, O’Reilly P, Costigan C, O’Gorman C, Murphy AM.

Ir Med J. 2018 Oct 11;111(9):819.

PMID:
30556667
24.

An Assessment of the Paediatric Internship at University Hospital Limerick over a 30 Month Period

O’Sullivan DM, Kavanagh EE, Ul-Azam S, O’Reilly P, Murphy AM, O’Gorman CS.

Ir Med J. 2018 Aug 13;111(7):796. No abstract available.

PMID:
30520289
25.

Evidence for gene-environment correlation in child feeding: Links between common genetic variation for BMI in children and parental feeding practices.

Selzam S, McAdams TA, Coleman JRI, Carnell S, O'Reilly PF, Plomin R, Llewellyn CH.

PLoS Genet. 2018 Nov 20;14(11):e1007757. doi: 10.1371/journal.pgen.1007757. eCollection 2018 Nov.

26.

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, Elosua R, Enroth S, Erzurumluoglu AM, Ferreira T, Frånberg M, Franco OH, Gandin I, Gasparini P, Giedraitis V, Gieger C, Girotto G, Goel A, Gow AJ, Gudnason V, Guo X, Gyllensten U, Hamsten A, Harris TB, Harris SE, Hartman CA, Havulinna AS, Hicks AA, Hofer E, Hofman A, Hottenga JJ, Huffman JE, Hwang SJ, Ingelsson E, James A, Jansen R, Jarvelin MR, Joehanes R, Johansson Å, Johnson AD, Joshi PK, Jousilahti P, Jukema JW, Jula A, Kähönen M, Kathiresan S, Keavney BD, Khaw KT, Knekt P, Knight J, Kolcic I, Kooner JS, Koskinen S, Kristiansson K, Kutalik Z, Laan M, Larson M, Launer LJ, Lehne B, Lehtimäki T, Liewald DCM, Lin L, Lind L, Lindgren CM, Liu Y, Loos RJF, Lopez LM, Lu Y, Lyytikäinen LP, Mahajan A, Mamasoula C, Marrugat J, Marten J, Milaneschi Y, Morgan A, Morris AP, Morrison AC, Munson PJ, Nalls MA, Nandakumar P, Nelson CP, Niiranen T, Nolte IM, Nutile T, Oldehinkel AJ, Oostra BA, O'Reilly PF, Org E, Padmanabhan S, Palmas W, Palotie A, Pattie A, Penninx BWJH, Perola M, Peters A, Polasek O, Pramstaller PP, Nguyen QT, Raitakari OT, Ren M, Rettig R, Rice K, Ridker PM, Ried JS, Riese H, Ripatti S, Robino A, Rose LM, Rotter JI, Rudan I, Ruggiero D, Saba Y, Sala CF, Salomaa V, Samani NJ, Sarin AP, Schmidt R, Schmidt H, Shrine N, Siscovick D, Smith AV, Snieder H, Sõber S, Sorice R, Starr JM, Stott DJ, Strachan DP, Strawbridge RJ, Sundström J, Swertz MA, Taylor KD, Teumer A, Tobin MD, Tomaszewski M, Toniolo D, Traglia M, Trompet S, Tuomilehto J, Tzourio C, Uitterlinden AG, Vaez A, van der Most PJ, van Duijn CM, Vergnaud AC, Verwoert GC, Vitart V, Völker U, Vollenweider P, Vuckovic D, Watkins H, Wild SH, Willemsen G, Wilson JF, Wright AF, Yao J, Zemunik T, Zhang W, Attia JR, Butterworth AS, Chasman DI, Conen D, Cucca F, Danesh J, Hayward C, Howson JMM, Laakso M, Lakatta EG, Langenberg C, Melander O, Mook-Kanamori DO, Palmer CNA, Risch L, Scott RA, Scott RJ, Sever P, Spector TD, van der Harst P, Wareham NJ, Zeggini E, Levy D, Munroe PB, Newton-Cheh C, Brown MJ, Metspalu A, Hung AM, O'Donnell CJ, Edwards TL; Million Veteran Program, Psaty BM, Tzoulaki I, Barnes MR, Wain LV, Elliott P, Caulfield MJ.

Nat Genet. 2018 Dec;50(12):1755. doi: 10.1038/s41588-018-0297-3.

27.

Impact of Variable RNA-Sequencing Depth on Gene Expression Signatures and Target Compound Robustness: Case Study Examining Brain Tumor (Glioma) Disease Progression.

Stupnikov A, O'Reilly PG, McInerney CE, Roddy AC, Dunne PD, Gilmore A, Ellis HP, Flannery T, Healy E, McIntosh SA, Savage K, Kurian KM, Emmert-Streib F, Prise KM, Salto-Tellez M, McArt DG.

JCO Precis Oncol. 2018 Sep 13;2. doi: 10.1200/PO.18.00014.

28.

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, Elosua R, Enroth S, Erzurumluoglu AM, Ferreira T, Frånberg M, Franco OH, Gandin I, Gasparini P, Giedraitis V, Gieger C, Girotto G, Goel A, Gow AJ, Gudnason V, Guo X, Gyllensten U, Hamsten A, Harris TB, Harris SE, Hartman CA, Havulinna AS, Hicks AA, Hofer E, Hofman A, Hottenga JJ, Huffman JE, Hwang SJ, Ingelsson E, James A, Jansen R, Jarvelin MR, Joehanes R, Johansson Å, Johnson AD, Joshi PK, Jousilahti P, Jukema JW, Jula A, Kähönen M, Kathiresan S, Keavney BD, Khaw KT, Knekt P, Knight J, Kolcic I, Kooner JS, Koskinen S, Kristiansson K, Kutalik Z, Laan M, Larson M, Launer LJ, Lehne B, Lehtimäki T, Liewald DCM, Lin L, Lind L, Lindgren CM, Liu Y, Loos RJF, Lopez LM, Lu Y, Lyytikäinen LP, Mahajan A, Mamasoula C, Marrugat J, Marten J, Milaneschi Y, Morgan A, Morris AP, Morrison AC, Munson PJ, Nalls MA, Nandakumar P, Nelson CP, Niiranen T, Nolte IM, Nutile T, Oldehinkel AJ, Oostra BA, O'Reilly PF, Org E, Padmanabhan S, Palmas W, Palotie A, Pattie A, Penninx BWJH, Perola M, Peters A, Polasek O, Pramstaller PP, Nguyen QT, Raitakari OT, Ren M, Rettig R, Rice K, Ridker PM, Ried JS, Riese H, Ripatti S, Robino A, Rose LM, Rotter JI, Rudan I, Ruggiero D, Saba Y, Sala CF, Salomaa V, Samani NJ, Sarin AP, Schmidt R, Schmidt H, Shrine N, Siscovick D, Smith AV, Snieder H, Sõber S, Sorice R, Starr JM, Stott DJ, Strachan DP, Strawbridge RJ, Sundström J, Swertz MA, Taylor KD, Teumer A, Tobin MD, Tomaszewski M, Toniolo D, Traglia M, Trompet S, Tuomilehto J, Tzourio C, Uitterlinden AG, Vaez A, van der Most PJ, van Duijn CM, Vergnaud AC, Verwoert GC, Vitart V, Völker U, Vollenweider P, Vuckovic D, Watkins H, Wild SH, Willemsen G, Wilson JF, Wright AF, Yao J, Zemunik T, Zhang W, Attia JR, Butterworth AS, Chasman DI, Conen D, Cucca F, Danesh J, Hayward C, Howson JMM, Laakso M, Lakatta EG, Langenberg C, Melander O, Mook-Kanamori DO, Palmer CNA, Risch L, Scott RA, Scott RJ, Sever P, Spector TD, van der Harst P, Wareham NJ, Zeggini E, Levy D, Munroe PB, Newton-Cheh C, Brown MJ, Metspalu A, Hung AM, O'Donnell CJ, Edwards TL, Psaty BM, Tzoulaki I, Barnes MR, Wain LV, Elliott P, Caulfield MJ; Million Veteran Program.

Nat Genet. 2018 Oct;50(10):1412-1425. doi: 10.1038/s41588-018-0205-x. Epub 2018 Sep 17. Erratum in: Nat Genet. 2018 Dec;50(12):1755.

29.

Association of Polygenic Risk for Attention-Deficit/Hyperactivity Disorder With Co-occurring Traits and Disorders.

Du Rietz E, Coleman J, Glanville K, Choi SW, O'Reilly PF, Kuntsi J.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Jul;3(7):635-643. doi: 10.1016/j.bpsc.2017.11.013. Epub 2017 Dec 14.

30.

Using genetic data to strengthen causal inference in observational research.

Pingault JB, O'Reilly PF, Schoeler T, Ploubidis GB, Rijsdijk F, Dudbridge F.

Nat Rev Genet. 2018 Sep;19(9):566-580. doi: 10.1038/s41576-018-0020-3. Review.

PMID:
29872216
31.

Discursive constructions of professional identity in policy and regulatory discourse.

Fealy G, Hegarty JM, McNamara M, Casey M, O'Leary D, Kennedy C, O'Reilly P, O'Connell R, Brady AM, Nicholson E.

J Adv Nurs. 2018 May 23. doi: 10.1111/jan.13723. [Epub ahead of print]

PMID:
29791020
32.

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.

Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, Blackwood DRH, Bryois J, Buttenschøn HN, Bybjerg-Grauholm J, Cai N, Castelao E, Christensen JH, Clarke TK, Coleman JIR, Colodro-Conde L, Couvy-Duchesne B, Craddock N, Crawford GE, Crowley CA, Dashti HS, Davies G, Deary IJ, Degenhardt F, Derks EM, Direk N, Dolan CV, Dunn EC, Eley TC, Eriksson N, Escott-Price V, Kiadeh FHF, Finucane HK, Forstner AJ, Frank J, Gaspar HA, Gill M, Giusti-Rodríguez P, Goes FS, Gordon SD, Grove J, Hall LS, Hannon E, Hansen CS, Hansen TF, Herms S, Hickie IB, Hoffmann P, Homuth G, Horn C, Hottenga JJ, Hougaard DM, Hu M, Hyde CL, Ising M, Jansen R, Jin F, Jorgenson E, Knowles JA, Kohane IS, Kraft J, Kretzschmar WW, Krogh J, Kutalik Z, Lane JM, Li Y, Li Y, Lind PA, Liu X, Lu L, MacIntyre DJ, MacKinnon DF, Maier RM, Maier W, Marchini J, Mbarek H, McGrath P, McGuffin P, Medland SE, Mehta D, Middeldorp CM, Mihailov E, Milaneschi Y, Milani L, Mill J, Mondimore FM, Montgomery GW, Mostafavi S, Mullins N, Nauck M, Ng B, Nivard MG, Nyholt DR, O'Reilly PF, Oskarsson H, Owen MJ, Painter JN, Pedersen CB, Pedersen MG, Peterson RE, Pettersson E, Peyrot WJ, Pistis G, Posthuma D, Purcell SM, Quiroz JA, Qvist P, Rice JP, Riley BP, Rivera M, Saeed Mirza S, Saxena R, Schoevers R, Schulte EC, Shen L, Shi J, Shyn SI, Sigurdsson E, Sinnamon GBC, Smit JH, Smith DJ, Stefansson H, Steinberg S, Stockmeier CA, Streit F, Strohmaier J, Tansey KE, Teismann H, Teumer A, Thompson W, Thomson PA, Thorgeirsson TE, Tian C, Traylor M, Treutlein J, Trubetskoy V, Uitterlinden AG, Umbricht D, Van der Auwera S, van Hemert AM, Viktorin A, Visscher PM, Wang Y, Webb BT, Weinsheimer SM, Wellmann J, Willemsen G, Witt SH, Wu Y, Xi HS, Yang J, Zhang F; eQTLGen; 23andMe, Arolt V, Baune BT, Berger K, Boomsma DI, Cichon S, Dannlowski U, de Geus ECJ, DePaulo JR, Domenici E, Domschke K, Esko T, Grabe HJ, Hamilton SP, Hayward C, Heath AC, Hinds DA, Kendler KS, Kloiber S, Lewis G, Li QS, Lucae S, Madden PFA, Magnusson PK, Martin NG, McIntosh AM, Metspalu A, Mors O, Mortensen PB, Müller-Myhsok B, Nordentoft M, Nöthen MM, O'Donovan MC, Paciga SA, Pedersen NL, Penninx BWJH, Perlis RH, Porteous DJ, Potash JB, Preisig M, Rietschel M, Schaefer C, Schulze TG, Smoller JW, Stefansson K, Tiemeier H, Uher R, Völzke H, Weissman MM, Werge T, Winslow AR, Lewis CM, Levinson DF, Breen G, Børglum AD, Sullivan PF; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.

Nat Genet. 2018 May;50(5):668-681. doi: 10.1038/s41588-018-0090-3. Epub 2018 Apr 26.

33.

Clinical, biochemical, and genetic features of four patients with short-chain enoyl-CoA hydratase (ECHS1) deficiency.

Fitzsimons PE, Alston CL, Bonnen PE, Hughes J, Crushell E, Geraghty MT, Tetreault M, O'Reilly P, Twomey E, Sheikh Y, Walsh R, Waterham HR, Ferdinandusse S, Wanders RJA, Taylor RW, Pitt JJ, Mayne PD.

Am J Med Genet A. 2018 May;176(5):1115-1127. doi: 10.1002/ajmg.a.38658. Epub 2018 Mar 25.

34.

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Jiang X, O'Reilly PF, Aschard H, Hsu YH, Richards JB, Dupuis J, Ingelsson E, Karasik D, Pilz S, Berry D, Kestenbaum B, Zheng J, Luan J, Sofianopoulou E, Streeten EA, Albanes D, Lutsey PL, Yao L, Tang W, Econs MJ, Wallaschofski H, Völzke H, Zhou A, Power C, McCarthy MI, Michos ED, Boerwinkle E, Weinstein SJ, Freedman ND, Huang WY, Van Schoor NM, van der Velde N, Groot LCPGM, Enneman A, Cupples LA, Booth SL, Vasan RS, Liu CT, Zhou Y, Ripatti S, Ohlsson C, Vandenput L, Lorentzon M, Eriksson JG, Shea MK, Houston DK, Kritchevsky SB, Liu Y, Lohman KK, Ferrucci L, Peacock M, Gieger C, Beekman M, Slagboom E, Deelen J, Heemst DV, Kleber ME, März W, de Boer IH, Wood AC, Rotter JI, Rich SS, Robinson-Cohen C, den Heijer M, Jarvelin MR, Cavadino A, Joshi PK, Wilson JF, Hayward C, Lind L, Michaëlsson K, Trompet S, Zillikens MC, Uitterlinden AG, Rivadeneira F, Broer L, Zgaga L, Campbell H, Theodoratou E, Farrington SM, Timofeeva M, Dunlop MG, Valdes AM, Tikkanen E, Lehtimäki T, Lyytikäinen LP, Kähönen M, Raitakari OT, Mikkilä V, Ikram MA, Sattar N, Jukema JW, Wareham NJ, Langenberg C, Forouhi NG, Gundersen TE, Khaw KT, Butterworth AS, Danesh J, Spector T, Wang TJ, Hyppönen E, Kraft P, Kiel DP.

Nat Commun. 2018 Jan 17;9(1):260. doi: 10.1038/s41467-017-02662-2.

35.

Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis.

O'Reilly PJ, Ding Q, Akthar S, Cai G, Genschmer KR, Patel DF, Jackson PL, Viera L, Roda M, Locy ML, Bernstein EA, Lloyd CM, Bernstein KE, Snelgrove RJ, Blalock JE.

JCI Insight. 2017 Nov 16;2(22). pii: 91923. doi: 10.1172/jci.insight.91923. eCollection 2017 Nov 16.

36.

Widespread covariation of early environmental exposures and trait-associated polygenic variation.

Krapohl E, Hannigan LJ, Pingault JB, Patel H, Kadeva N, Curtis C, Breen G, Newhouse SJ, Eley TC, O'Reilly PF, Plomin R.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11727-11732. doi: 10.1073/pnas.1707178114. Epub 2017 Oct 16.

37.

Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P, Liu C, Cook JP, Kraja AT, Drenos F, Loh M, Verweij N, Marten J, Karaman I, Segura Lepe MP, O'Reilly PF, Knight J, Snieder H, Kato N, He J, Tai ES, Said MA, Porteous D, Alver M, Poulter N, Farrall M, Gansevoort RT, Padmanabhan S, Mägi R, Stanton A, Connell J, Bakker SJL, Metspalu A, Shields DC, Thom S, Brown M, Sever P, Esko T, Hayward C, van der Harst P, Saleheen D, Chowdhury R, Chambers JC, Chasman DI, Chakravarti A, Newton-Cheh C, Lindgren CM, Levy D, Kooner JS, Keavney B, Tomaszewski M, Samani NJ, Howson JMM, Tobin MD, Munroe PB, Ehret GB, Wain LV; International Consortium of Blood Pressure (ICBP) 1000G Analyses, The CHD Exome+ Consortium, The ExomeBP Consortium, The T2D-GENES Consortium, The GoT2DGenes Consortium, The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium, The International Genomics of Blood Pressure (iGEN-BP) Consortium, Barnes MR, Tzoulaki I, Caulfield MJ, Elliott P; UK Biobank CardioMetabolic Consortium BP working group.

Nat Genet. 2017 Sep 27;49(10):1558. doi: 10.1038/ng1017-1558a. No abstract available.

38.

Predicting educational achievement from DNA.

Selzam S, Krapohl E, von Stumm S, O'Reilly PF, Rimfeld K, Kovas Y, Dale PS, Lee JJ, Plomin R.

Mol Psychiatry. 2018 Jan;23(1):161. doi: 10.1038/mp.2017.203. Epub 2017 Sep 26.

39.

Multi-polygenic score approach to trait prediction.

Krapohl E, Patel H, Newhouse S, Curtis CJ, von Stumm S, Dale PS, Zabaneh D, Breen G, O'Reilly PF, Plomin R.

Mol Psychiatry. 2018 May;23(5):1368-1374. doi: 10.1038/mp.2017.163. Epub 2017 Aug 8.

40.

Correction: Assessing the facilitators and barriers of interdisciplinary team working in primary care using normalisation process theory: An integrative review.

O'Reilly P, Lee SH, O'Sullivan M, Cullen W, Kennedy C, MacFarlane A.

PLoS One. 2017 Jul 24;12(7):e0181893. doi: 10.1371/journal.pone.0181893. eCollection 2017.

41.

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, Hwang SJ, Guo X, Kutalik Z, Trompet S, Shrine N, Teumer A, Ried JS, Bis JC, Smith AV, Amin N, Nolte IM, Lyytikäinen LP, Mahajan A, Wareham NJ, Hofer E, Joshi PK, Kristiansson K, Traglia M, Havulinna AS, Goel A, Nalls MA, Sõber S, Vuckovic D, Luan J, Del Greco M F, Ayers KL, Marrugat J, Ruggiero D, Lopez LM, Niiranen T, Enroth S, Jackson AU, Nelson CP, Huffman JE, Zhang W, Marten J, Gandin I, Harris SE, Zemunik T, Lu Y, Evangelou E, Shah N, de Borst MH, Mangino M, Prins BP, Campbell A, Li-Gao R, Chauhan G, Oldmeadow C, Abecasis G, Abedi M, Barbieri CM, Barnes MR, Batini C, Beilby J, Blake T, Boehnke M, Bottinger EP, Braund PS, Brown M, Brumat M, Campbell H, Chambers JC, Cocca M, Collins F, Connell J, Cordell HJ, Damman JJ, Davies G, de Geus EJ, de Mutsert R, Deelen J, Demirkale Y, Doney ASF, Dörr M, Farrall M, Ferreira T, Frånberg M, Gao H, Giedraitis V, Gieger C, Giulianini F, Gow AJ, Hamsten A, Harris TB, Hofman A, Holliday EG, Hui J, Jarvelin MR, Johansson Å, Johnson AD, Jousilahti P, Jula A, Kähönen M, Kathiresan S, Khaw KT, Kolcic I, Koskinen S, Langenberg C, Larson M, Launer LJ, Lehne B, Liewald DCM, Lin L, Lind L, Mach F, Mamasoula C, Menni C, Mifsud B, Milaneschi Y, Morgan A, Morris AD, Morrison AC, Munson PJ, Nandakumar P, Nguyen QT, Nutile T, Oldehinkel AJ, Oostra BA, Org E, Padmanabhan S, Palotie A, Paré G, Pattie A, Penninx BWJH, Poulter N, Pramstaller PP, Raitakari OT, Ren M, Rice K, Ridker PM, Riese H, Ripatti S, Robino A, Rotter JI, Rudan I, Saba Y, Saint Pierre A, Sala CF, Sarin AP, Schmidt R, Scott R, Seelen MA, Shields DC, Siscovick D, Sorice R, Stanton A, Stott DJ, Sundström J, Swertz M, Taylor KD, Thom S, Tzoulaki I, Tzourio C, Uitterlinden AG, Völker U, Vollenweider P, Wild S, Willemsen G, Wright AF, Yao J, Thériault S, Conen D, Attia J, Sever P, Debette S, Mook-Kanamori DO, Zeggini E, Spector TD, van der Harst P, Palmer CNA, Vergnaud AC, Loos RJF, Polasek O, Starr JM, Girotto G, Hayward C, Kooner JS, Lindgren CM, Vitart V, Samani NJ, Tuomilehto J, Gyllensten U, Knekt P, Deary IJ, Ciullo M, Elosua R, Keavney BD, Hicks AA, Scott RA, Gasparini P, Laan M, Liu Y, Watkins H, Hartman CA, Salomaa V, Toniolo D, Perola M, Wilson JF, Schmidt H, Zhao JH, Lehtimäki T, van Duijn CM, Gudnason V, Psaty BM, Peters A, Rettig R, James A, Jukema JW, Strachan DP, Palmas W, Metspalu A, Ingelsson E, Boomsma DI, Franco OH, Bochud M, Newton-Cheh C, Munroe PB, Elliott P, Chasman DI, Chakravarti A, Knight J, Morris AP, Levy D, Tobin MD, Snieder H, Caulfield MJ, Ehret GB.

Hypertension. 2017 Jul 24. pii: HYPERTENSIONAHA.117.09438. doi: 10.1161/HYPERTENSIONAHA.117.09438. [Epub ahead of print]

42.

Genome-Wide Polygenic Scores Predict Reading Performance Throughout the School Years.

Selzam S, Dale PS, Wagner RK, DeFries JC, Cederlöf M, O'Reilly PF, Krapohl E, Plomin R.

Sci Stud Read. 2017 Jul 4;21(4):334-349. doi: 10.1080/10888438.2017.1299152. Epub 2017 Mar 28.

43.

Rotavirus Gastroenteritis is Associated with Increased Morbidity and Mortality in Children with Inherited Metabolic Disorders.

Smith A, Mannion M, O'Reilly P, Crushell E, Hughes J, Knerr I, Gavin P, Monavari A.

Ir Med J. 2017 Apr 10;110(4):546.

PMID:
28665085
44.

Challenges in accessing and interviewing participants with severe mental illness.

Newman D, O'Reilly P, Lee SH, Kennedy C.

Nurse Res. 2017 Jun 22;25(1):37-42. doi: 10.7748/nr.2017.e1443.

PMID:
28639528
45.

Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival.

Alderdice M, Dunne PD, Cole AJ, O'Reilly PG, McArt DG, Bingham V, Fuchs MA, McQuaid S, Loughrey MB, Murray GI, Samuel LM, Lawler M, Wilson RH, Salto-Tellez M, Coyle VM.

Mod Pathol. 2017 Sep;30(9):1287-1298. doi: 10.1038/modpathol.2017.47. Epub 2017 Jun 16.

46.

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification.

Dunne PD, Alderdice M, O'Reilly PG, Roddy AC, McCorry AMB, Richman S, Maughan T, McDade SS, Johnston PG, Longley DB, Kay E, McArt DG, Lawler M.

Nat Commun. 2017 May 31;8:15657. doi: 10.1038/ncomms15657.

47.

Assessing the facilitators and barriers of interdisciplinary team working in primary care using normalisation process theory: An integrative review.

O'Reilly P, Lee SH, O'Sullivan M, Cullen W, Kennedy C, MacFarlane A.

PLoS One. 2017 May 18;12(5):e0177026. doi: 10.1371/journal.pone.0177026. eCollection 2017. Review. Erratum in: PLoS One. 2017 Jul 24;12 (7):e0181893.

48.

Exploring the attitudes, knowledge and beliefs of nurses and midwives of the healthcare needs of the LGBTQ population: An integrative review.

Stewart K, O'Reilly P.

Nurse Educ Today. 2017 Jun;53:67-77. doi: 10.1016/j.nedt.2017.04.008. Epub 2017 Apr 18. Review.

PMID:
28448883
49.

Multivariate simulation framework reveals performance of multi-trait GWAS methods.

Porter HF, O'Reilly PF.

Sci Rep. 2017 Mar 13;7:38837. doi: 10.1038/srep38837.

50.

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P, Liu C, Cook JP, Kraja AT, Drenos F, Loh M, Verweij N, Marten J, Karaman I, Lepe MP, O'Reilly PF, Knight J, Snieder H, Kato N, He J, Tai ES, Said MA, Porteous D, Alver M, Poulter N, Farrall M, Gansevoort RT, Padmanabhan S, Mägi R, Stanton A, Connell J, Bakker SJ, Metspalu A, Shields DC, Thom S, Brown M, Sever P, Esko T, Hayward C, van der Harst P, Saleheen D, Chowdhury R, Chambers JC, Chasman DI, Chakravarti A, Newton-Cheh C, Lindgren CM, Levy D, Kooner JS, Keavney B, Tomaszewski M, Samani NJ, Howson JM, Tobin MD, Munroe PB, Ehret GB, Wain LV; International Consortium of Blood Pressure (ICBP) 1000G Analyses; BIOS Consortium; Lifelines Cohort Study; Understanding Society Scientific group; CHD Exome+ Consortium; ExomeBP Consortium; T2D-GENES Consortium; GoT2DGenes Consortium; Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; UK Biobank CardioMetabolic Consortium BP working group.

Nat Genet. 2017 Mar;49(3):403-415. doi: 10.1038/ng.3768. Epub 2017 Jan 30. Erratum in: Nat Genet. 2017 Sep 27;49(10 ):1558.

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