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RASSF1A controls tissue stiffness and cancer stem-like cells in lung adenocarcinoma.

Pankova D, Jiang Y, Chatzifrangkeskou M, Vendrell I, Buzzelli J, Ryan A, Brown C, O'Neill E.

EMBO J. 2019 Jul 1;38(13):e100532. doi: 10.15252/embj.2018100532. Epub 2019 May 27.


Lessons from the reestablishment of Public Health Laboratory activities in Puerto Rico after Hurricane Maria.

Hardy MC, Stinnett RC, Kines KJ, Rivera-Nazario DM, Lowe DE, Mercante AM, Gonzalez Jimenez N, Cuevas Ruiz RI, Rivera Arbolay HI, Gonzalez Peña RL, Toro M, Trujillo AA, Pappas CL, Llewellyn AC, Candal F, Burgos Garay M, Gomez GA, Concepcion Acevedo J, Ansbro M, Moura H, Shaw MW, Muehlenbachs A, Romanoff LC, Sunshine BJ, Rose DA, Patel A, Shapiro CN, Luna-Pinto SC, Pillai SK, O'Neill E.

Nat Commun. 2019 Jun 20;10(1):2720. doi: 10.1038/s41467-019-10776-y. Review.


Euglena Central Metabolic Pathways and Their Subcellular Locations.

Inwongwan S, Kruger NJ, Ratcliffe RG, O'Neill EC.

Metabolites. 2019 Jun 14;9(6). pii: E115. doi: 10.3390/metabo9060115.


RASSF1A is required for the maintenance of nuclear actin levels.

Chatzifrangkeskou M, Pefani DE, Eyres M, Vendrell I, Fischer R, Pankova D, O'Neill E.

EMBO J. 2019 Jun 7. pii: e101168. doi: 10.15252/embj.2018101168. [Epub ahead of print]


RASSF1A controls tissue stiffness and cancer stem-like cells in lung adenocarcinoma.

Pankova D, Jiang Y, Chatzifrangkeskou M, Vendrell I, Buzzelli J, Ryan A, Brown C, O'Neill E.

EMBO J. 2019 May 27. pii: e100532. doi: 10.15252/embj.2018100532. [Epub ahead of print]


A novel medical device coating prevents Staphylococcus aureus biofilm formation on medical device surfaces.

Hogan S, Kasotakis E, Maher S, Cavanagh B, O'Gara JP, Pandit A, Keyes TE, Devocelle M, O'Neill E.

FEMS Microbiol Lett. 2019 May 1;366(9). pii: fnz107. doi: 10.1093/femsle/fnz107.


Targeted antibiotic discovery through biosynthesis-associated resistance determinants: target directed genome mining.

O'Neill EC, Schorn M, Larson CB, Millán-Aguiñaga N.

Crit Rev Microbiol. 2019 Apr 15:1-23. doi: 10.1080/1040841X.2019.1590307. [Epub ahead of print]


Reduced respiratory motion artefact in constant TR multi-slice MRI of the mouse.

Kinchesh P, Allen PD, Gilchrist S, Kersemans V, Lanfredini S, Thapa A, O'Neill E, Smart SC.

Magn Reson Imaging. 2019 Jul;60:1-6. doi: 10.1016/j.mri.2019.03.018. Epub 2019 Mar 27.


L-alpha-aminoadipic acid restricts dopaminergic neurodegeneration and motor deficits in an inflammatory model of Parkinson's disease in male rats.

O'Neill E, Chiara Goisis R, Haverty R, Harkin A.

J Neurosci Res. 2019 Jul;97(7):804-816. doi: 10.1002/jnr.24420. Epub 2019 Mar 29.


Eating Breakfast and Family Meals in Adolescence: The Role of Body Image.

Ramseyer Winter V, Jones A, O'Neill E.

Soc Work Public Health. 2019;34(3):230-238. doi: 10.1080/19371918.2019.1575314. Epub 2019 Feb 14.


An analysis of childhood consultations in general practice: a multi-practice study.

O'Doherty J, Hannigan A, Hickey L, Cullen W, O'Gorman C, O'Connor R, Glynn L, O'Neill E, O'Regan A.

Ir J Med Sci. 2019 Feb 12. doi: 10.1007/s11845-019-01982-0. [Epub ahead of print]


Transcriptome, proteome and draft genome of Euglena gracilis.

Ebenezer TE, Zoltner M, Burrell A, Nenarokova A, Novák Vanclová AMG, Prasad B, Soukal P, Santana-Molina C, O'Neill E, Nankissoor NN, Vadakedath N, Daiker V, Obado S, Silva-Pereira S, Jackson AP, Devos DP, Lukeš J, Lebert M, Vaughan S, Hampl V, Carrington M, Ginger ML, Dacks JB, Kelly S, Field MC.

BMC Biol. 2019 Feb 7;17(1):11. doi: 10.1186/s12915-019-0626-8.


Cancer stem cell mobilization and therapeutic targeting of the 5T4 oncofetal antigen.

Harrop R, O'Neill E, Stern PL.

Ther Adv Vaccines Immunother. 2019 Jan 25;7:2515135518821623. doi: 10.1177/2515135518821623. eCollection 2019. Review.


Study protocol: a multi-centre randomised study of induction chemotherapy followed by capecitabine ± nelfinavir with high- or standard-dose radiotherapy for locally advanced pancreatic cancer (SCALOP-2).

Strauss VY, Shaw R, Virdee PS, Hurt CN, Ward E, Tranter B, Patel N, Bridgewater J, Parsons P, Radhakrishna G, O'Neill E, Sebag-Montefiore D, Hawkins M, Corrie PG, Maughan T, Mukherjee S.

BMC Cancer. 2019 Feb 4;19(1):121. doi: 10.1186/s12885-019-5307-z.


Targeted Rediscovery and Biosynthesis of the Farnesyl-Transferase Inhibitor Pepticinnamin E.

Santa Maria KC, Chan AN, O'Neill EM, Li B.

Chembiochem. 2019 Jun 3;20(11):1387-1393. doi: 10.1002/cbic.201900025. Epub 2019 May 2.


Repositioning Tacrolimus: Evaluation of the Effect of Short-Term Tacrolimus Treatment on Osteoprogenitor Cells and Primary Cells for Bone Regenerative Engineering.

O'Neill E, Rajpura K, Carbone EJ, Awale G, Kan HM, Lo KW.

Assay Drug Dev Technol. 2019 Feb/Mar;17(2):77-88. doi: 10.1089/adt.2018.876. Epub 2019 Jan 9.


Double-blind, randomized clinical trial assessing the efficacy and safety of early initiation of sitagliptin during metformin uptitration in the treatment of patients with type 2 diabetes: The CompoSIT-M study.

Frias JP, Zimmer Z, Lam RLH, Amorin G, Ntabadde C, Iredale C, O'Neill EA, Engel SS, Kaufman KD, Makimura H, Crutchlow MF.

Diabetes Obes Metab. 2019 May;21(5):1128-1135. doi: 10.1111/dom.13626. Epub 2019 Feb 17.


Blackcurrant (Ribes nigrum) Prevents Obesity-Induced Nonalcoholic Steatohepatitis in Mice.

Lee Y, Pham TX, Bae M, Hu S, O'Neill E, Chun OK, Han MJ, Koo SI, Park YK, Lee JY.

Obesity (Silver Spring). 2019 Jan;27(1):112-120. doi: 10.1002/oby.22353.


Nuclear/Cytoplasmic Fractionation to Study Hippo Effectors.

Chatzifrangkeskou M, O'Neill E.

Methods Mol Biol. 2019;1893:115-119. doi: 10.1007/978-1-4939-8910-2_10.


What effect do point of care fees have on childhood consultations in general practice?

O'Regan A, Cullen W, O'Gorman C, Hickey L, O'Neill E, O'Doherty J, Hannigan A.

BMC Health Serv Res. 2018 Dec 18;18(1):979. doi: 10.1186/s12913-018-3800-8.


One-year parasitological screening of stray dogs and cats in County Dublin, Ireland.

Garcia-Campos A, Power C, O'Shaughnessy J, Browne C, Lawlor A, McCarthy G, O'Neill EJ, de Waal T.

Parasitology. 2018 Dec 18:1-7. doi: 10.1017/S0031182018002020. [Epub ahead of print]


Subcutaneous Inoculation of 3D Pancreatic Cancer Spheroids Results in Development of Reproducible Stroma-Rich Tumors.

Durymanov M, Kroll C, Permyakova A, O'Neill E, Sulaiman R, Person M, Reineke J.

Transl Oncol. 2019 Jan;12(1):180-189. doi: 10.1016/j.tranon.2018.10.003. Epub 2018 Oct 25.


Speech Perception with Spectrally Non-overlapping Maskers as Measure of Spectral Resolution in Cochlear Implant Users.

O'Neill ER, Kreft HA, Oxenham AJ.

J Assoc Res Otolaryngol. 2019 Apr;20(2):151-167. doi: 10.1007/s10162-018-00702-2. Epub 2018 Nov 19.


Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix.

Yuzhalin AE, Gordon-Weeks AN, Tognoli ML, Jones K, Markelc B, Konietzny R, Fischer R, Muth A, O'Neill E, Thompson PR, Venables PJ, Kessler BM, Lim SY, Muschel RJ.

Nat Commun. 2018 Nov 14;9(1):4783. doi: 10.1038/s41467-018-07306-7.


Double-blind, randomized clinical trial comparing the efficacy and safety of continuing or discontinuing the dipeptidyl peptidase-4 inhibitor sitagliptin when initiating insulin glargine therapy in patients with type 2 diabetes: The CompoSIT-I Study.

Roussel R, Duran-García S, Zhang Y, Shah S, Darmiento C, Shankar RR, Golm GT, Lam RLH, O'Neill EA, Gantz I, Kaufman KD, Engel SS.

Diabetes Obes Metab. 2018 Nov 4. doi: 10.1111/dom.13574. [Epub ahead of print]


Drawing on biology to inspire molecular design: a redox-responsive MRI probe based on Gd(iii)-nicotinamide.

Harris M, Kolanowski JL, O'Neill ES, Henoumont C, Laurent S, Parac-Vogt TN, New EJ.

Chem Commun (Camb). 2018 Nov 15;54(92):12986-12989. doi: 10.1039/c8cc07092j.


Phevamine A, a small molecule that suppresses plant immune responses.

O'Neill EM, Mucyn TS, Patteson JB, Finkel OM, Chung EH, Baccile JA, Massolo E, Schroeder FC, Dangl JL, Li B.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9514-E9522. doi: 10.1073/pnas.1803779115. Epub 2018 Sep 20.


Efficacy and safety of sitagliptin added to treatment of patients with type 2 diabetes inadequately controlled with premixed insulin.

Yu M, Shankar RR, Zhang R, Zhang Y, Lin J, O'Neill EA, Chen G, Liu S, Tu Y, Engel SS.

Diabetes Obes Metab. 2019 Feb;21(2):408-411. doi: 10.1111/dom.13517. Epub 2018 Oct 3.


Exploring fasting practices for critical care patients - A web-based survey of UK intensive care units.

Segaran E, Lovejoy TD, Proctor C, Bispham WL, Jordan R, Jenkins B, O'Neill E, Harkess SE, Terblanche M.

J Intensive Care Soc. 2018 Aug;19(3):188-195. doi: 10.1177/1751143717748555. Epub 2018 Jan 15.


Effect of carbamide peroxide bleaching on enamel characteristics and susceptibility to further discoloration.

Farawati FAL, Hsu SM, O'Neill E, Neal D, Clark A, Esquivel-Upshaw J.

J Prosthet Dent. 2019 Feb;121(2):340-346. doi: 10.1016/j.prosdent.2018.03.006. Epub 2018 Aug 20.


Targeting the noradrenergic system for anti-inflammatory and neuroprotective effects: implications for Parkinson's disease.

O'Neill E, Harkin A.

Neural Regen Res. 2018 Aug;13(8):1332-1337. doi: 10.4103/1673-5374.235219. Review.


A randomized clinical trial of the efficacy and safety of sitagliptin compared with dapagliflozin in patients with type 2 diabetes mellitus and mild renal insufficiency: The CompoSIT-R study.

Scott R, Morgan J, Zimmer Z, Lam RLH, O'Neill EA, Kaufman KD, Engel SS, Raji A.

Diabetes Obes Metab. 2018 Dec;20(12):2876-2884. doi: 10.1111/dom.13473. Epub 2018 Aug 16.


Opportunities and perspectives for utilisation of co-products in the meat industry.

Lynch SA, Mullen AM, O'Neill E, Drummond L, Álvarez C.

Meat Sci. 2018 Oct;144:62-73. doi: 10.1016/j.meatsci.2018.06.019. Epub 2018 Jun 19. Review.


Efficacy and Safety of Sitagliptin in Hispanic/Latino Patients with Type 2 Diabetes: A Pooled Analysis from Ten Randomized, Placebo-Controlled Phase 3 Clinical Trials.

Raji A, Long J, Lam RLH, O'Neill EA, Engel SS.

Diabetes Ther. 2018 Aug;9(4):1581-1589. doi: 10.1007/s13300-018-0461-x. Epub 2018 Jun 23.


MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B.

Pefani DE, Tognoli ML, Pirincci Ercan D, Gorgoulis V, O'Neill E.

EMBO J. 2018 Aug 1;37(15). pii: e98760. doi: 10.15252/embj.201798760. Epub 2018 May 22.


The role of inflammation in subventricular zone cancer.

Bardella C, Al-Shammari AR, Soares L, Tomlinson I, O'Neill E, Szele FG.

Prog Neurobiol. 2018 Nov;170:37-52. doi: 10.1016/j.pneurobio.2018.04.007. Epub 2018 Apr 11. Review.


Persistent DNA strand breaks induce a CAF-like phenotype in normal fibroblasts.

Legrand AJ, Poletto M, Pankova D, Clementi E, Moore J, Castro-Giner F, Ryan AJ, O'Neill E, Markkanen E, Dianov GL.

Oncotarget. 2018 Feb 7;9(17):13666-13681. doi: 10.18632/oncotarget.24446. eCollection 2018 Mar 2.


Initial Public Health Laboratory Response After Hurricane Maria - Puerto Rico, 2017.

Concepción-Acevedo J, Patel A, Luna-Pinto C, Peña RG, Cuevas Ruiz RI, Arbolay HR, Toro M, Deseda C, De Jesus VR, Ribot E, Gonzalez JQ, Rao G, De Leon Salazar A, Ansbro M, White BB, Hardy MC, Georgi JC, Stinnett R, Mercante AM, Lowe D, Martin H, Starks A, Metchock B, Johnston S, Dalton T, Joglar O, Stafford C, Youngblood M, Klein K, Lindstrom S, Berman L, Galloway R, Schafer IJ, Walke H, Stoddard R, Connelly R, McCaffery E, Rowlinson MC, Soroka S, Tranquillo DT, Gaynor A, Mangal C, Wroblewski K, Muehlenbachs A, Salerno RM, Lozier M, Sunshine B, Shapiro C, Rose D, Funk R, Pillai SK, O'Neill E.

MMWR Morb Mortal Wkly Rep. 2018 Mar 23;67(11):333-336. doi: 10.15585/mmwr.mm6711a5.


Insights into toxic Prymnesium parvum blooms: the role of sugars and algal viruses.

Wagstaff BA, Hems ES, Rejzek M, Pratscher J, Brooks E, Kuhaudomlarp S, O'Neill EC, Donaldson MI, Lane S, Currie J, Hindes AM, Malin G, Murrell JC, Field RA.

Biochem Soc Trans. 2018 Apr 17;46(2):413-421. doi: 10.1042/BST20170393. Epub 2018 Mar 14. Review.


Author Correction: Energy use and life cycle greenhouse gas emissions of drones for commercial package delivery.

Stolaroff JK, Samaras C, O'Neill ER, Lubers A, Mitchell AS, Ceperley D.

Nat Commun. 2018 Mar 8;9(1):1054. doi: 10.1038/s41467-018-03457-9.


Energy use and life cycle greenhouse gas emissions of drones for commercial package delivery.

Stolaroff JK, Samaras C, O'Neill ER, Lubers A, Mitchell AS, Ceperley D.

Nat Commun. 2018 Feb 13;9(1):409. doi: 10.1038/s41467-017-02411-5. Erratum in: Nat Commun. 2018 Mar 8;9(1):1054.


Surface water flooding, groundwater contamination, and enteric disease in developed countries: A scoping review of connections and consequences.

Andrade L, O'Dwyer J, O'Neill E, Hynds P.

Environ Pollut. 2018 May;236:540-549. doi: 10.1016/j.envpol.2018.01.104. Review.


The roles of ions on bone regeneration.

O'Neill E, Awale G, Daneshmandi L, Umerah O, Lo KW.

Drug Discov Today. 2018 Apr;23(4):879-890. doi: 10.1016/j.drudis.2018.01.049. Epub 2018 Feb 3. Review.


RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.

Papaspyropoulos A, Bradley L, Thapa A, Leung CY, Toskas K, Koennig D, Pefani DE, Raso C, Grou C, Hamilton G, Vlahov N, Grawenda A, Haider S, Chauhan J, Buti L, Kanapin A, Lu X, Buffa F, Dianov G, von Kriegsheim A, Matallanas D, Samsonova A, Zernicka-Goetz M, O'Neill E.

Nat Commun. 2018 Jan 30;9(1):424. doi: 10.1038/s41467-017-02786-5.


Characteristics of Elderly Patients Initiating Sitagliptin or Non-DPP-4-Inhibitor Oral Antihyperglycemic Agents: Analysis of a Cross-Sectional US Claims Database.

Wang T, McNeill AM, Chen Y, O'Neill EA, Engel SS.

Diabetes Ther. 2018 Feb;9(1):309-315. doi: 10.1007/s13300-017-0360-6. Epub 2018 Jan 12.


A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.

Komseli ES, Pateras IS, Krejsgaard T, Stawiski K, Rizou SV, Polyzos A, Roumelioti FM, Chiourea M, Mourkioti I, Paparouna E, Zampetidis CP, Gumeni S, Trougakos IP, Pefani DE, O'Neill E, Gagos S, Eliopoulos AG, Fendler W, Chowdhury D, Bartek J, Gorgoulis VG.

BMC Genomics. 2018 Jan 10;19(1):37. doi: 10.1186/s12864-017-4375-1.


The β2-adrenoceptor agonist clenbuterol reduces the neuroinflammatory response, neutrophil infiltration and apoptosis following intra-striatal IL-1β administration to rats.

Griffin ÉW, Yssel JD, O'Neill E, Ryan KJ, Boyle N, Harper P, Harkin A, Connor T.

Immunopharmacol Immunotoxicol. 2018 Apr;40(2):99-106. doi: 10.1080/08923973.2017.1418882. Epub 2018 Jan 5.


Excisional biopsy of an extravesicular hemangioma.

Goldman C, Koch GE, Carvalho F, O'Neill EK, Stamatakis L.

Urol Case Rep. 2017 Nov 26;16:107-109. doi: 10.1016/j.eucr.2017.11.019. eCollection 2018 Jan. No abstract available.

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