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Items: 1 to 50 of 73

1.

Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen.

O'Meara TR, O'Meara MJ, Polvi EJ, Pourhaghighi MR, Liston SD, Lin ZY, Veri AO, Emili A, Gingras AC, Cowen LE.

PLoS Biol. 2019 Jul 8;17(7):e3000358. doi: 10.1371/journal.pbio.3000358. eCollection 2019 Jul.

2.

A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans.

Brimacombe CA, Burke JE, Parsa JY, Catania S, O'Meara TR, Witchley JN, Burrack LS, Madhani HD, Noble SM.

PLoS Biol. 2019 Jun 21;17(6):e3000331. doi: 10.1371/journal.pbio.3000331. eCollection 2019 Jun.

3.

mSphere of Influence: Start with an Interesting Biological Phenomenon.

O'Meara T.

mSphere. 2019 Jun 19;4(3). pii: e00299-19. doi: 10.1128/mSphere.00299-19.

4.

Defining Risk of Late Recurrence in Early-Stage Estrogen Receptor-Positive Breast Cancer: Clinical Versus Molecular Tools.

Foldi J, O'Meara T, Marczyk M, Sanft T, Silber A, Pusztai L.

J Clin Oncol. 2019 Jun 1;37(16):1365-1369. doi: 10.1200/JCO.18.01933. Epub 2019 Apr 3. No abstract available.

PMID:
30943126
5.

Immune microenvironment of triple-negative breast cancer in African-American and Caucasian women.

O'Meara T, Safonov A, Casadevall D, Qing T, Silber A, Killelea B, Hatzis C, Pusztai L.

Breast Cancer Res Treat. 2019 May;175(1):247-259. doi: 10.1007/s10549-019-05156-5. Epub 2019 Feb 6.

PMID:
30725384
6.

Insights into the host-pathogen interaction: C. albicans manipulation of macrophage pyroptosis.

O'Meara TR, Cowen LE.

Microb Cell. 2018 Nov 12;5(12):566-568. doi: 10.15698/mic2018.12.662.

7.

Residency Training: Progressive gait difficulty and incontinence in a 40-year-old man with HIV.

Silverman A, O'Meara T, Le L, Robertson K, Spudich S.

Neurology. 2018 Dec 4;91(23):1065-1070. doi: 10.1212/WNL.0000000000006619. No abstract available.

PMID:
30510020
8.

Incorporating Genomics Into the Care of Patients With Advanced Breast Cancer.

Kratz J, Burkard M, O'Meara T, Pusztai L, Veitch Z, Bedard PL.

Am Soc Clin Oncol Educ Book. 2018 May 23;38:56-64. doi: 10.1200/EDBK_200731. Review.

PMID:
30231387
9.

High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis.

O'Meara TR, Duah K, Guo CX, Maxson ME, Gaudet RG, Koselny K, Wellington M, Powers ME, MacAlpine J, O'Meara MJ, Veri AO, Grinstein S, Noble SM, Krysan D, Gray-Owen SD, Cowen LE.

MBio. 2018 Aug 21;9(4). pii: e01581-18. doi: 10.1128/mBio.01581-18.

10.

Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space.

Veri AO, Miao Z, Shapiro RS, Tebbji F, O'Meara TR, Kim SH, Colazo J, Tan K, Vyas VK, Whiteway M, Robbins N, Wong KH, Cowen LE.

PLoS Genet. 2018 Mar 28;14(3):e1007270. doi: 10.1371/journal.pgen.1007270. eCollection 2018 Mar.

11.

Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes.

Maxson ME, Naj X, O'Meara TR, Plumb JD, Cowen LE, Grinstein S.

Elife. 2018 Mar 19;7. pii: e34798. doi: 10.7554/eLife.34798.

12.

Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy.

Eichler F, Duncan C, Musolino PL, Orchard PJ, De Oliveira S, Thrasher AJ, Armant M, Dansereau C, Lund TC, Miller WP, Raymond GV, Sankar R, Shah AJ, Sevin C, Gaspar HB, Gissen P, Amartino H, Bratkovic D, Smith NJC, Paker AM, Shamir E, O'Meara T, Davidson D, Aubourg P, Williams DA.

N Engl J Med. 2017 Oct 26;377(17):1630-1638. doi: 10.1056/NEJMoa1700554. Epub 2017 Oct 4.

13.

Rising tides, cumulative impacts and cascading changes to estuarine ecosystem functions.

O'Meara TA, Hillman JR, Thrush SF.

Sci Rep. 2017 Aug 31;7(1):10218. doi: 10.1038/s41598-017-11058-7.

14.

The Hsp90 Chaperone Network Modulates Candida Virulence Traits.

O'Meara TR, Robbins N, Cowen LE.

Trends Microbiol. 2017 Oct;25(10):809-819. doi: 10.1016/j.tim.2017.05.003. Epub 2017 May 23. Review.

15.

Staurosporine Induces Filamentation in the Human Fungal Pathogen Candida albicans via Signaling through Cyr1 and Protein Kinase A.

Xie JL, O'Meara TR, Polvi EJ, Robbins N, Cowen LE.

mSphere. 2017 Mar 1;2(2). pii: e00056-17. doi: 10.1128/mSphere.00056-17. eCollection 2017 Mar-Apr.

16.

Extensive functional redundancy in the regulation of Candida albicans drug resistance and morphogenesis by lysine deacetylases Hos2, Hda1, Rpd3 and Rpd31.

Li X, Robbins N, O'Meara TR, Cowen LE.

Mol Microbiol. 2017 Feb;103(4):635-656. doi: 10.1111/mmi.13578. Epub 2016 Dec 14.

17.

Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast.

Campbell MJ, Baehner F, O'Meara T, Ojukwu E, Han B, Mukhtar R, Tandon V, Endicott M, Zhu Z, Wong J, Krings G, Au A, Gray JW, Esserman L.

Breast Cancer Res Treat. 2017 Jan;161(1):17-28. doi: 10.1007/s10549-016-4036-0. Epub 2016 Oct 26.

18.

Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress.

O'Meara TR, Veri AO, Polvi EJ, Li X, Valaei SF, Diezmann S, Cowen LE.

PLoS Genet. 2016 Jun 24;12(6):e1006142. doi: 10.1371/journal.pgen.1006142. eCollection 2016 Jun.

19.

The Cryptococcus neoformans alkaline response pathway: identification of a novel rim pathway activator.

Ost KS, O'Meara TR, Huda N, Esher SK, Alspaugh JA.

PLoS Genet. 2015 Apr 10;11(4):e1005159. doi: 10.1371/journal.pgen.1005159. eCollection 2015 Apr.

20.

Global analysis of fungal morphology exposes mechanisms of host cell escape.

O'Meara TR, Veri AO, Ketela T, Jiang B, Roemer T, Cowen LE.

Nat Commun. 2015 Mar 31;6:6741. doi: 10.1038/ncomms7741.

21.

Opportunistic yeast pathogens: reservoirs, virulence mechanisms, and therapeutic strategies.

Polvi EJ, Li X, O'Meara TR, Leach MD, Cowen LE.

Cell Mol Life Sci. 2015 Jun;72(12):2261-87. doi: 10.1007/s00018-015-1860-z. Epub 2015 Feb 21. Review.

PMID:
25700837
22.

Fitness Trade-Offs Associated with the Evolution of Resistance to Antifungal Drug Combinations.

Hill JA, O'Meara TR, Cowen LE.

Cell Rep. 2015 Feb 10;10(5):809-819. doi: 10.1016/j.celrep.2015.01.009. Epub 2015 Feb 5.

23.

Predicting Alzheimer disease with β-amyloid imaging: results from the Australian imaging, biomarkers, and lifestyle study of ageing.

Rowe CC, Bourgeat P, Ellis KA, Brown B, Lim YY, Mulligan R, Jones G, Maruff P, Woodward M, Price R, Robins P, Tochon-Danguy H, O'Keefe G, Pike KE, Yates P, Szoeke C, Salvado O, Macaulay SL, O'Meara T, Head R, Cobiac L, Savage G, Martins R, Masters CL, Ames D, Villemagne VL.

Ann Neurol. 2013 Dec;74(6):905-13. doi: 10.1002/ana.24040.

24.

Hsp90-dependent regulatory circuitry controlling temperature-dependent fungal development and virulence.

O'Meara TR, Cowen LE.

Cell Microbiol. 2014 Apr;16(4):473-81. doi: 10.1111/cmi.12266. Epub 2014 Feb 14. Review.

PMID:
24438186
25.

The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host.

O'Meara TR, Xu W, Selvig KM, O'Meara MJ, Mitchell AP, Alspaugh JA.

Mol Cell Biol. 2014 Feb;34(4):673-84. doi: 10.1128/MCB.01359-13. Epub 2013 Dec 9.

26.

Factors affecting subjective memory complaints in the AIBL aging study: biomarkers, memory, affect, and age.

Buckley R, Saling MM, Ames D, Rowe CC, Lautenschlager NT, Macaulay SL, Martins RN, Masters CL, O'Meara T, Savage G, Szoeke C, Villemagne VL, Ellis KA; Australian Imaging Biomarkers and Lifestyle Study of Aging (AIBL) Research Group.

Int Psychogeriatr. 2013 Aug;25(8):1307-15. doi: 10.1017/S1041610213000665. Epub 2013 May 22.

PMID:
23693133
27.

Cryptococcus neoformans Rim101 is associated with cell wall remodeling and evasion of the host immune responses.

O'Meara TR, Holmer SM, Selvig K, Dietrich F, Alspaugh JA.

MBio. 2013 Jan 15;4(1). pii: e00522-12. doi: 10.1128/mBio.00522-12.

28.

Research and standardization in Alzheimer's trials: reaching international consensus.

Carrillo MC, Rowe CC, Szoeke C, Masters CL, Ames D, O'Meara T, Macaulay SL, Milner A, Ellis KA, Maruff P, Rainey-Smith SR, Martins RN, Bain LJ, Head RJ; NIA/Alzheimer Association and International Working Group.

Alzheimers Dement. 2013 Mar;9(2):160-8. doi: 10.1016/j.jalz.2012.10.006. Epub 2012 Dec 23.

PMID:
23266004
29.

The Cryptococcus neoformans capsule: a sword and a shield.

O'Meara TR, Alspaugh JA.

Clin Microbiol Rev. 2012 Jul;25(3):387-408. doi: 10.1128/CMR.00001-12. Review.

30.

Influence of antibiotic susceptibility patterns on empiric antibiotic prescribing for children hospitalized with community-acquired pneumonia.

Ambroggio L, Tabb LP, O'Meara T, Sheffler-Collins S, McGowan KL, Shah SS.

Pediatr Infect Dis J. 2012 Apr;31(4):331-6. doi: 10.1097/INF.0b013e3182489cc4.

31.

Cryptococcal titan cell formation is regulated by G-protein signaling in response to multiple stimuli.

Okagaki LH, Wang Y, Ballou ER, O'Meara TR, Bahn YS, Alspaugh JA, Xue C, Nielsen K.

Eukaryot Cell. 2011 Oct;10(10):1306-16. doi: 10.1128/EC.05179-11. Epub 2011 Aug 5.

32.

Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host.

O'Meara TR, Hay C, Price MS, Giles S, Alspaugh JA.

Eukaryot Cell. 2010 Aug;9(8):1193-202. doi: 10.1128/EC.00098-10. Epub 2010 Jun 25.

33.

Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule.

O'Meara TR, Norton D, Price MS, Hay C, Clements MF, Nichols CB, Alspaugh JA.

PLoS Pathog. 2010 Feb 19;6(2):e1000776. doi: 10.1371/journal.ppat.1000776.

34.

Early treatment with alglucosidase alpha prolongs long-term survival of infants with Pompe disease.

Kishnani PS, Corzo D, Leslie ND, Gruskin D, Van der Ploeg A, Clancy JP, Parini R, Morin G, Beck M, Bauer MS, Jokic M, Tsai CE, Tsai BW, Morgan C, O'Meara T, Richards S, Tsao EC, Mandel H.

Pediatr Res. 2009 Sep;66(3):329-35. doi: 10.1203/PDR.0b013e3181b24e94.

35.

Sorption mechanisms of cephapirin, a veterinary antibiotic, onto quartz and feldspar minerals as detected by Raman spectroscopy.

Peterson JW, O'Meara TA, Seymour MD, Wang W, Gu B.

Environ Pollut. 2009 Jun;157(6):1849-56. doi: 10.1016/j.envpol.2009.01.017. Epub 2009 Feb 26.

PMID:
19246140
36.

The Halogen assay--a new technique for measuring airborne allergen.

Tovey E, Lucca SD, Poulos L, O'Meara T.

Methods Mol Med. 2008;138:227-46. doi: 10.1007/978-1-59745-366-0_19.

PMID:
18612612
37.

Measurement of personal exposure to outdoor aeromycota in northern New South Wales, Australia.

Green BJ, O'Meara T, Sercombe J, Tovey E.

Ann Agric Environ Med. 2006;13(2):225-34.

PMID:
17195994
38.

The reduction of rhinitis symptoms by nasal filters during natural exposure to ragweed and grass pollen.

O'Meara TJ, Sercombe JK, Morgan G, Reddel HK, Xuan W, Tovey ER.

Allergy. 2005 Apr;60(4):529-32.

PMID:
15727589
39.

Bed covers and dust mites.

Tovey ER, O'Meara TJ, Marks GB.

N Engl J Med. 2003 Oct 23;349(17):1668-71; author reply 1668-71. No abstract available.

PMID:
14575053
40.

Personal exposure to house dust mite allergen in bed: nasal air sampling and reservoir allergen levels.

Gore RB, Hadi EA, Craven M, Smillie FI, O'Meara TJ, Tovey ER, Woodcock A, Custovic A.

Clin Exp Allergy. 2002 Jun;32(6):856-9.

PMID:
12047431
41.

Inhaled latex allergen (Hev b 1).

Poulos LM, O'Meara TJ, Hamilton RG, Tovey ER.

J Allergy Clin Immunol. 2002 Apr;109(4):701-6.

PMID:
11941322
42.

Exposure to mite and cat allergens on a range of clothing items at home and the transfer of cat allergen in the workplace.

De Lucca SD, O'meara TJ, Tovey ER.

J Allergy Clin Immunol. 2000 Nov;106(5):874-9.

PMID:
11080709
43.

Monitoring personal allergen exposure.

O'Meara T, Tovey E.

Clin Rev Allergy Immunol. 2000 Jun;18(3):341-95. Review. No abstract available.

PMID:
10981265
44.

A new method for simultaneous immunodetection and morphologic identification of individual sources of pollen allergens.

Razmovski V, O'Meara TJ, Taylor DJ, Tovey ER.

J Allergy Clin Immunol. 2000 Apr;105(4):725-31.

PMID:
10756222
45.

Measurement and characterization of cockroach allergens detected during normal domestic activity.

De Lucca SD, Taylor DJ, O'Meara TJ, Jones AS, Tovey ER.

J Allergy Clin Immunol. 1999 Sep;104(3 Pt 1):672-80.

PMID:
10482845
46.

Detection of inhaled Der p 1.

Poulos LM, O'Meara TJ, Sporik R, Tovey ER.

Clin Exp Allergy. 1999 Sep;29(9):1232-8.

PMID:
10469032
47.

Intelligent agent for collaborative diagnosis.

Mulvihill C, Patel A, O'Meara T.

Stud Health Technol Inform. 1998;52 Pt 1:232-6.

PMID:
10384453
48.

Mite allergen (Der p 1) is not only carried on mite feces.

De Lucca S, Sporik R, O'Meara TJ, Tovey ER.

J Allergy Clin Immunol. 1999 Jan;103(1 Pt 1):174-5. No abstract available.

PMID:
9893203
49.

Detection of inhaled cat allergen.

O'Meara TJ, De Lucca S, Sporik R, Graham A, Tovey E.

Lancet. 1998 May 16;351(9114):1488-9. No abstract available.

PMID:
9605809
50.

Antibody responses to Lucilia cuprina in sheep selected for resistance or susceptibility to L. cuprina.

O'Meara TJ, Nesa M, Sandeman RM.

Parasite Immunol. 1997 Dec;19(12):535-43.

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