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Items: 12


Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer.

Lubbock ALR, Stewart GD, O'Mahony FC, Laird A, Mullen P, O'Donnell M, Powles T, Harrison DJ, Overton IM.

BMC Med. 2017 Jun 26;15(1):118. doi: 10.1186/s12916-017-0874-9.


Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer.

Stewart GD, O'Mahony FC, Laird A, Eory L, Lubbock AL, Mackay A, Nanda J, O'Donnell M, Mullen P, McNeill SA, Riddick AC, Berney D, Bex A, Aitchison M, Overton IM, Harrison DJ, Powles T.

Clin Cancer Res. 2015 Sep 15;21(18):4212-23. doi: 10.1158/1078-0432.CCR-15-0207. Epub 2015 May 26.


Translational research will fail without surgical leadership: SCOTRRCC a successful surgeon-led Nationwide translational research infrastructure in renal cancer.

Stewart GD, Riddick AC, Rae F, Marshall C, MacLeod L, O'Mahony FC, Laird A, Alan McNeill S, O'Connor KM, O'Donnell M, Fineron P, McLaren DB, Aitchison M, Oades G, Hair J, Seywright M, Little B, Nairn R, Lamb G, Macleod T, Dunn I, Ramsey A, Campbell R, Leung S, McLornan L, Rahilly M, Wilson I, Pollock AM, Harrison DJ.

Surgeon. 2015 Aug;13(4):181-6. doi: 10.1016/j.surge.2015.03.001. Epub 2015 Apr 30.


Carbonic anhydrase 9 expression increases with vascular endothelial growth factor-targeted therapy and is predictive of outcome in metastatic clear cell renal cancer.

Stewart GD, O'Mahony FC, Laird A, Rashid S, Martin SA, Eory L, Lubbock AL, Nanda J, O'Donnell M, Mackay A, Mullen P, McNeill SA, Riddick AC, Aitchison M, Berney D, Bex A, Overton IM, Harrison DJ, Powles T.

Eur Urol. 2014 Nov;66(5):956-63. doi: 10.1016/j.eururo.2014.04.007. Epub 2014 May 10.


The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer.

Sharpe K, Stewart GD, Mackay A, Van Neste C, Rofe C, Berney D, Kayani I, Bex A, Wan E, O'Mahony FC, O'Donnell M, Chowdhury S, Doshi R, Ho-Yen C, Gerlinger M, Baker D, Smith N, Davies B, Sahdev A, Boleti E, De Meyer T, Van Criekinge W, Beltran L, Lu YJ, Harrison DJ, Reynolds AR, Powles T.

Clin Cancer Res. 2013 Dec 15;19(24):6924-34. doi: 10.1158/1078-0432.CCR-13-1631. Epub 2013 Oct 15.


Differential expression of prognostic proteomic markers in primary tumour, venous tumour thrombus and metastatic renal cell cancer tissue and correlation with patient outcome.

Laird A, O'Mahony FC, Nanda J, Riddick AC, O'Donnell M, Harrison DJ, Stewart GD.

PLoS One. 2013;8(4):e60483. doi: 10.1371/journal.pone.0060483. Epub 2013 Apr 5.


The use of reverse phase protein arrays (RPPA) to explore protein expression variation within individual renal cell cancers.

O'Mahony FC, Nanda J, Laird A, Mullen P, Caldwell H, Overton IM, Eory L, O'Donnell M, Faratian D, Powles T, Harrison DJ, Stewart GD.

J Vis Exp. 2013 Jan 22;(71). pii: 50221. doi: 10.3791/50221.


The use of automated quantitative analysis to evaluate epithelial-to-mesenchymal transition associated proteins in clear cell renal cell carcinoma.

O'Mahony FC, Faratian D, Varley J, Nanda J, Theodoulou M, Riddick AC, Harrison DJ, Stewart GD.

PLoS One. 2012;7(2):e31557. doi: 10.1371/journal.pone.0031557. Epub 2012 Feb 21.


What can molecular pathology contribute to the management of renal cell carcinoma?

Stewart GD, O'Mahony FC, Powles T, Riddick AC, Harrison DJ, Faratian D.

Nat Rev Urol. 2011 May;8(5):255-65. doi: 10.1038/nrurol.2011.43. Epub 2011 Apr 12. Review.


Toxicological profiling of chemical and environmental samples using panels of test organisms and optical oxygen respirometry.

Zitova A, O'Mahony FC, Cross M, Davenport J, Papkovsky DB.

Environ Toxicol. 2009 Apr;24(2):116-27. doi: 10.1002/tox.20387.


Optical oxygen microrespirometry as a platform for environmental toxicology and animal model studies.

O'Mahony FC, O'Donovan C, Hynes J, Moore T, Davenport J, Papkovsky DB.

Environ Sci Technol. 2005 Jul 1;39(13):5010-4.


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