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Items: 1 to 50 of 196

1.

Too MAD or not MAD enough: The duplicitous role of the spindle assembly checkpoint protein MAD2 in cancer.

Bates M, Furlong F, Gallagher MF, Spillane CD, McCann A, O'Toole S, O'Leary JJ.

Cancer Lett. 2019 Oct 5. pii: S0304-3835(19)30496-3. doi: 10.1016/j.canlet.2019.10.005. [Epub ahead of print]

PMID:
31593803
2.

Emergency intraoperative vascular surgery consultations at a tertiary academic center.

Blackwood SL, O'Leary JJ, Scully RE, Lotto CE, Nguyen LL, Gravereaux EC, Menard MT, Ozaki CK, Gates JD, Belkin M.

J Vasc Surg. 2019 Sep 9. pii: S0741-5214(19)31742-2. doi: 10.1016/j.jvs.2019.05.064. [Epub ahead of print]

PMID:
31515177
3.

Insights From a Short-Term Protein-Calorie Restriction Exploratory Trial in Elective Carotid Endarterectomy Patients.

Kip P, Trocha KM, Tao M, O'leary JJ, Ruske J, Giulietti JM, Trevino-Villareal JH, MacArthur MR, Bolze A, Burak MF, Patterson S, Ho KJ, Carmody RN, Guzman RJ, Mitchell JR, Ozaki CK.

Vasc Endovascular Surg. 2019 Aug;53(6):470-476. doi: 10.1177/1538574419856453. Epub 2019 Jun 19.

PMID:
31216949
4.

Mitochondrial Reactive Oxygen Species Contribute to Pathological Inflammation During Influenza A Virus Infection in Mice.

To EE, Erlich JR, Liong F, Luong R, Liong S, Esaq F, Oseghale O, Anthony D, McQualter J, Bozinovski S, Vlahos R, O'Leary JJ, Brooks DA, Selemidis S.

Antioxid Redox Signal. 2019 Jul 12. doi: 10.1089/ars.2019.7727. [Epub ahead of print]

PMID:
31190565
5.

Suppression of Natural Killer cell NKG2D and CD226 anti-tumour cascades by platelet cloaked cancer cells: Implications for the metastatic cascade.

Cluxton CD, Spillane C, O'Toole SA, Sheils O, Gardiner CM, O'Leary JJ.

PLoS One. 2019 Mar 25;14(3):e0211538. doi: 10.1371/journal.pone.0211538. eCollection 2019.

6.

A retrospective validation of the FocalPoint GS slide profiler NFR technology by analysis of interval disease outcomes compared with manual cytology.

Nuttall DS, Hillier S, Clayton HR, Savage AJ, Martin CM, O'Leary JJ.

Cancer Cytopathol. 2019 Apr;127(4):240-246. doi: 10.1002/cncy.22109. Epub 2019 Mar 2.

PMID:
30825407
7.

Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice.

To EE, Erlich J, Liong F, Luong R, Liong S, Bozinovski S, Seow HJ, O'Leary JJ, Brooks DA, Vlahos R, Selemidis S.

Sci Rep. 2019 Feb 20;9(1):2366. doi: 10.1038/s41598-019-38864-5.

8.

The potential of biobanked liquid based cytology samples for cervical cancer screening using Raman spectroscopy.

Traynor D, Duraipandian S, Bhatia R, Cuschieri K, Martin CM, O'Leary JJ, Lyng FM.

J Biophotonics. 2019 Jul;12(7):e201800377. doi: 10.1002/jbio.201800377. Epub 2019 Mar 25.

PMID:
30653819
9.

Which primary care practitioners have poor human papillomavirus (HPV) knowledge? A step towards informing the development of professional education initiatives.

McSherry LA, O'Leary E, Dombrowski SU, Francis JJ, Martin CM, O'Leary JJ, Sharp L; ATHENS (A Trial of HPV Education and Support) Group.

PLoS One. 2018 Dec 13;13(12):e0208482. doi: 10.1371/journal.pone.0208482. eCollection 2018.

10.

Raman spectroscopic detection of high-grade cervical cytology: Using morphologically normal appearing cells.

Duraipandian S, Traynor D, Kearney P, Martin C, O'Leary JJ, Lyng FM.

Sci Rep. 2018 Oct 9;8(1):15048. doi: 10.1038/s41598-018-33417-8.

11.

Clinical performance of the Cobas 4800 HPV test and the Aptima HPV assay in the management of women referred to colposcopy with minor cytological abnormalities.

Tewari P, White C, Kelly L, Pilkington L, Keegan H, D'Arcy T, Toole SO, Sharp L, O'Leary JJ, Martin CM.

Diagn Cytopathol. 2018 Dec;46(12):987-992. doi: 10.1002/dc.24066. Epub 2018 Oct 3.

PMID:
30284405
12.

Socio-economic variations in anticipated adverse reactions to testing HPV positive: Implications for the introduction of primary HPV-based cervical screening.

O'Connor M, O'Leary E, Waller J, Gallagher P, Martin CM, O'Leary JJ, Sharp L; Irish Cervical Screening Research Consortium (CERVIVA).

Prev Med. 2018 Oct;115:90-96. doi: 10.1016/j.ypmed.2018.08.017. Epub 2018 Aug 23.

PMID:
30144488
13.

Improved removal of blood contamination from ThinPrep cervical cytology samples for Raman spectroscopic analysis.

Traynor D, Duraipandian S, Martin CM, O'Leary JJ, Lyng FM.

J Biomed Opt. 2018 May;23(5):1-8. doi: 10.1117/1.JBO.23.5.055001.

14.

A study of hormonal effects in cervical smear samples using Raman spectroscopy.

Traynor D, Kearney P, Ramos I, Martin CM, O'Leary JJ, Lyng FM.

J Biophotonics. 2018 Jun;11(6):e201700240. doi: 10.1002/jbio.201700240. Epub 2018 Jan 17.

PMID:
29215211
15.

Raman spectral signatures of cervical exfoliated cells from liquid-based cytology samples.

Kearney P, Traynor D, Bonnier F, Lyng FM, O'Leary JJ, Martin CM.

J Biomed Opt. 2017 Oct;22(10):1-10. doi: 10.1117/1.JBO.22.10.105008.

16.

miR-223 potentially targets SWI/SNF complex protein SMARCD1 in atypical proliferative serous tumor and high-grade ovarian serous carcinoma.

Arts FA, Keogh L, Smyth P, O'Toole S, Ta R, Gleeson N, O'Leary JJ, Flavin R, Sheils O.

Hum Pathol. 2017 Dec;70:98-104. doi: 10.1016/j.humpath.2017.10.008. Epub 2017 Oct 24.

PMID:
29079174
17.

Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC.

MacDonagh L, Gallagher MF, Ffrench B, Gasch C, Breen E, Gray SG, Nicholson S, Leonard N, Ryan R, Young V, O'Leary JJ, Cuffe S, Finn SP, O'Byrne KJ, Barr MP.

Oncotarget. 2017 Aug 3;8(42):72544-72563. doi: 10.18632/oncotarget.19881. eCollection 2017 Sep 22.

18.

CD10-/ALDH- cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy.

Ffrench B, Gasch C, Hokamp K, Spillane C, Blackshields G, Mahgoub TM, Bates M, Kehoe L, Mooney A, Doyle R, Doyle B, O'Donnell D, Gleeson N, Hennessy BT, Stordal B, O'Riain C, Lambkin H, O'Toole S, O'Leary JJ, Gallagher MF.

Cell Death Dis. 2017 Oct 19;8(10):e3128. doi: 10.1038/cddis.2017.379.

19.

MyD88 is an essential component of retinoic acid-induced differentiation in human pluripotent embryonal carcinoma cells.

Sulaiman G, Cooke A, Ffrench B, Gasch C, Abdullai OA, O'Connor K, Elbaruni S, Blackshields G, Spillane C, Keegan H, McEneaney V, Knittel R, Rogers A, Jeffery IB, Doyle B, Bates M, d'Adhemar C, Lee MY, Campbell EL, Moynagh PN, Higgins DG, O'Toole S, O'Neill L, O'Leary JJ, Gallagher MF.

Cell Death Differ. 2017 Nov;24(11):1975-1986. doi: 10.1038/cdd.2017.124. Epub 2017 Sep 8.

20.

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.

To EE, Vlahos R, Luong R, Halls ML, Reading PC, King PT, Chan C, Drummond GR, Sobey CG, Broughton BRS, Starkey MR, van der Sluis R, Lewin SR, Bozinovski S, O'Neill LAJ, Quach T, Porter CJH, Brooks DA, O'Leary JJ, Selemidis S.

Nat Commun. 2017 Jul 12;8(1):69. doi: 10.1038/s41467-017-00057-x.

21.

Physical after-effects of colposcopy and related procedures, and their inter-relationship with psychological distress: a longitudinal survey.

O'Connor M, O'Brien K, Waller J, Gallagher P, D'Arcy T, Flannelly G, Martin CM, McRae J, Prendiville W, Ruttle C, White C, Pilkington L, O'Leary JJ, Sharp L; Irish Cervical Screening Research Consortium (CERVIVA).

BJOG. 2017 Aug;124(9):1402-1410. doi: 10.1111/1471-0528.14671. Epub 2017 May 31.

22.

Catching moving targets: cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention.

Gasch C, Ffrench B, O'Leary JJ, Gallagher MF.

Mol Cancer. 2017 Feb 23;16(1):43. doi: 10.1186/s12943-017-0601-3. Review.

23.

Cytokeratin 7 in Oropharyngeal Squamous Cell Carcinoma: A Junctional Biomarker for Human Papillomavirus-Related Tumors.

Woods RSR, Keegan H, White C, Tewari P, Toner M, Kennedy S, O'Regan EM, Martin CM, Timon CVI, O'Leary JJ.

Cancer Epidemiol Biomarkers Prev. 2017 May;26(5):702-710. doi: 10.1158/1055-9965.EPI-16-0619. Epub 2017 Jan 12.

24.

MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype.

Lynam-Lennon N, Heavey S, Sommerville G, Bibby BA, Ffrench B, Quinn J, Gasch C, O'Leary JJ, Gallagher MF, Reynolds JV, Maher SG.

Oncotarget. 2017 Feb 14;8(7):11400-11413. doi: 10.18632/oncotarget.13940.

25.

PO-14 - Tumour expression of coagulation proteases of the aPC pathway - a role in the pathogenesis of gynaecological cancers?

Martin F, Long JC, O'Toole SA, O'Leary JJ, Abu Saadeh F, Gleeson N, Norris LA.

Thromb Res. 2016 Apr;140 Suppl 1:S181. doi: 10.1016/S0049-3848(16)30147-5. Epub 2016 Apr 8.

PMID:
27161702
26.

Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines.

Dorris ER, Blackshields G, Sommerville G, Alhashemi M, Dias A, McEneaney V, Smyth P, O'Leary JJ, Sheils O.

Cancer Biol Ther. 2016 May 3;17(5):526-42. doi: 10.1080/15384047.2016.1139230. Epub 2016 Feb 1.

27.

Beware of Kinked Frontiers: A Systematic Review of the Choice of Comparator Strategies in Cost-Effectiveness Analyses of Human Papillomavirus Testing in Cervical Screening.

O'Mahony JF, Naber SK, Normand C, Sharp L, O'Leary JJ, de Kok IM.

Value Health. 2015 Dec;18(8):1138-51. doi: 10.1016/j.jval.2015.09.2939. Epub 2015 Nov 17. Review. Erratum in: Value Health. 2017 Mar;20(3):517.

28.

Endosomal gene expression: a new indicator for prostate cancer patient prognosis?

Johnson IR, Parkinson-Lawrence EJ, Keegan H, Spillane CD, Barry-O'Crowley J, Watson WR, Selemidis S, Butler LM, O'Leary JJ, Brooks DA.

Oncotarget. 2015 Nov 10;6(35):37919-29. doi: 10.18632/oncotarget.6114.

29.

Trends in, and predictors of, anxiety and specific worries following colposcopy: a 12-month longitudinal study.

O'Connor M, O'Leary E, Waller J, Gallagher P, D'arcy T, Flannelly G, Martin CM, McRae J, Prendiville W, Ruttle C, White C, Pilkington L, O'Leary JJ, Sharp L; Irish Cervical Screening Research Consortium (CERVIVA).

Psychooncology. 2016 May;25(5):597-604. doi: 10.1002/pon.3980. Epub 2015 Sep 22.

PMID:
26392040
30.

Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer.

McEvoy LM, O'Toole SA, Spillane CD, Martin CM, Gallagher MF, Stordal B, Blackshields G, Sheils O, O'Leary JJ.

BMC Cancer. 2015 Jul 25;15:547. doi: 10.1186/s12885-015-1539-8.

31.

Understanding Women's Differing Experiences of Distress after Colposcopy: A Qualitative Interview Study.

O'Connor M, Waller J, Gallagher P, Martin CM, O'Leary JJ, D'Arcy T, Prendiville W, Flannelly G, Sharp L; Irish Screening Research Consortium (CERVIVA).

Womens Health Issues. 2015 Sep-Oct;25(5):528-34. doi: 10.1016/j.whi.2015.05.009. Epub 2015 Jul 17.

PMID:
26189936
32.

Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines.

Busschots S, O'Toole S, O'Leary JJ, Stordal B.

MethodsX. 2014 Nov 25;2:8-13. doi: 10.1016/j.mex.2014.11.002. eCollection 2015.

33.

Adverse psychological outcomes following colposcopy and related procedures: a systematic review.

O'Connor M, Gallagher P, Waller J, Martin CM, O'Leary JJ, Sharp L; Irish Cervical Screening Research Consortium (CERVIVA).

BJOG. 2016 Jan;123(1):24-38. doi: 10.1111/1471-0528.13462. Epub 2015 Jun 22. Review.

34.

Enhanced regulation of cell cycle and suppression of osteoblast differentiation molecular signatures by prostate cancer stem-like holoclones.

Gallagher MF, Salley Y, Spillane CD, Ffrench B, El Baruni S, Blacksheilds G, Smyth P, Martin C, Sheils O, Watson W, O'Leary JJ.

J Clin Pathol. 2015 Sep;68(9):692-702. doi: 10.1136/jclinpath-2015-203001. Epub 2015 Jun 2.

PMID:
26038242
35.

Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells.

Busschots S, O'Toole S, O'Leary JJ, Stordal B.

Exp Cell Res. 2015 Aug 1;336(1):1-14. doi: 10.1016/j.yexcr.2014.12.001. Epub 2014 Dec 12.

PMID:
25499884
36.

Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention.

Ffrench B, Gasch C, O'Leary JJ, Gallagher MF.

Mol Cancer. 2014 Dec 11;13:262. doi: 10.1186/1476-4598-13-262. Review.

37.

Raman microspectroscopy for the early detection of pre-malignant changes in cervical tissue.

Rashid N, Nawaz H, Poon KW, Bonnier F, Bakhiet S, Martin C, O'Leary JJ, Byrne HJ, Lyng FM.

Exp Mol Pathol. 2014 Dec;97(3):554-64. doi: 10.1016/j.yexmp.2014.10.013. Epub 2014 Nov 3.

PMID:
25445502
38.

The use of MYBL2 as a novel candidate biomarker of cervical cancer.

Martin CM, Astbury K, Kehoe L, O'Crowley JB, O'Toole S, O'Leary JJ.

Methods Mol Biol. 2015;1249:241-51. doi: 10.1007/978-1-4939-2013-6_18.

PMID:
25348311
39.

Human papillomavirus DNA and mRNA prevalence and association with cervical cytological abnormalities in the Irish HIV population.

Loy A, McInerney J, Pilkington L, Keegan H, Delamere S, Martin CM, Sheils O, O'Leary JJ, Mulcahy F.

Int J STD AIDS. 2015 Oct;26(11):789-95. doi: 10.1177/0956462414553454. Epub 2014 Sep 25.

PMID:
25258395
40.

Influences on human papillomavirus (HPV)-related information needs among women having HPV tests for follow-up of abnormal cervical cytology.

O'Connor M, Costello L, Murphy J, Prendiville W, Martin CM, O'Leary JJ, Sharp L; Irish Screening Research Consortium (CERVIVA).

J Fam Plann Reprod Health Care. 2015 Apr;41(2):134-41. doi: 10.1136/jfprhc-2013-100750. Epub 2014 Sep 23.

41.

An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines.

Vencken SF, Sethupathy P, Blackshields G, Spillane C, Elbaruni S, Sheils O, Gallagher MF, O'Leary JJ.

BMC Genomics. 2014 Aug 25;15:711. doi: 10.1186/1471-2164-15-711.

42.

The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.

d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ.

PLoS One. 2014 Jun 30;9(6):e100816. doi: 10.1371/journal.pone.0100816. eCollection 2014. Erratum in: PLoS One. 2014;9(9):e108833.

43.

Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review.

Woods R Sr, O'Regan EM, Kennedy S, Martin C, O'Leary JJ, Timon C.

World J Clin Cases. 2014 Jun 16;2(6):172-93. doi: 10.12998/wjcc.v2.i6.172. Review.

44.

PARP Inhibitors as P-glyoprotein Substrates.

Lawlor D, Martin P, Busschots S, Thery J, O'Leary JJ, Hennessy BT, Stordal B.

J Pharm Sci. 2014 Jun;103(6):1913-20. doi: 10.1002/jps.23952. Epub 2014 Apr 3.

PMID:
24700236
45.

'I don't care whether it's HPV or ABC, I just want to know if I have cancer.' Factors influencing women's emotional responses to undergoing human papillomavirus testing in routine management in cervical screening: a qualitative study.

O'Connor M, Costello L, Murphy J, Prendiville W, Martin CM, O'Leary JJ, Sharp L; Irish Screening Research Consortium (CERVIVA).

BJOG. 2014 Oct;121(11):1421-9. doi: 10.1111/1471-0528.12741. Epub 2014 Apr 1.

46.

Molecular testing in oncology: problems, pitfalls and progress.

O'Brien CP, Taylor SE, O'Leary JJ, Finn SP.

Lung Cancer. 2014 Mar;83(3):309-15. doi: 10.1016/j.lungcan.2013.12.010. Epub 2014 Jan 3. Review.

PMID:
24472389
47.

Collateral sensitivity to cisplatin in KB-8-5-11 drug-resistant cancer cells.

Doherty B, Lawlor D, Gillet JP, Gottesman M, O'Leary JJ, Stordal B.

Anticancer Res. 2014 Jan;34(1):503-7.

PMID:
24403508
48.

Predictive values for molecular diagnostics: converting unknown unknowns to known unknowns.

O'Brien CP, Langabeer SE, O'Byrne KJ, O'Leary JJ, Finn SP.

Mol Diagn Ther. 2014 Feb;18(1):1-4. doi: 10.1007/s40291-013-0076-x. No abstract available.

PMID:
24338436
49.

Estrogen receptor alpha augments changes in hemostatic gene expression in HepG2 cells treated with estradiol and phytoestrogens.

Kelly LA, Seidlova-Wuttke D, Wuttke W, O'Leary JJ, Norris LA.

Phytomedicine. 2014 Jan 15;21(2):155-8. doi: 10.1016/j.phymed.2013.07.012. Epub 2013 Aug 23.

PMID:
23972791
50.

Evaluation of the clinical performance of the cobas 4800 HPV test in patients referred for colposcopy.

White C, Keegan H, Pilkington L, Ruttle C, Kerr P, Sharp L, O'Toole S, Turner M, Prendiville W, D'Arcy T, Fitzpatrick M, Lenehan P, Flannelly G, O'Leary JJ, Martin CM.

J Clin Microbiol. 2013 Oct;51(10):3415-7. doi: 10.1128/JCM.01949-13. Epub 2013 Jul 31.

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