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Items: 1 to 50 of 90

1.

'Non-self' Mutation: Double-stranded RNA elicits antiviral pathogenic response in a Drosophila model of expanded CAG repeat neurodegenerative diseases.

Eyk CL, Samaraweera SE, Scott A, Webber DL, Harvey DP, Mecinger O, O'Keefe LV, Cropley JE, Young P, Ho J, Suter C, Richards RI.

Hum Mol Genet. 2019 May 9. pii: ddz096. doi: 10.1093/hmg/ddz096. [Epub ahead of print]

PMID:
31071221
2.

Addressing transgender patients' barriers to access care.

Rowe D, Ng YC, OʼKeefe LC.

Nurse Pract. 2019 Jun;44(6):30-38. doi: 10.1097/01.NPR.0000558155.38478.8f.

PMID:
31033753
3.

Radiographic Prevalence of Symphysis Pubis Abnormalities and Clinical Outcomes in Patients With Femoroacetabular Impingement Syndrome.

Krishnamoorthy VP, Kunze KN, Beck EC, Cancienne JM, O'Keefe LS, Ayeni OR, Nho SJ.

Am J Sports Med. 2019 May;47(6):1467-1472. doi: 10.1177/0363546519837203. Epub 2019 Apr 17.

PMID:
30995415
4.

Innovations in Worksite Diagnosis of Urinary Tract Infections and the Occupational Health Nurse.

O'Keefe LC, Koelle P, McGee Z, Dewberry LS, Wright C, Stallings JE, Gates E, Chittur K.

Workplace Health Saf. 2019 Jun;67(6):268-274. doi: 10.1177/2165079919834310. Epub 2019 Mar 29.

PMID:
30924742
5.

Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan.

Xie J, de Souza Alves V, von der Haar T, O'Keefe L, Lenchine RV, Jensen KB, Liu R, Coldwell MJ, Wang X, Proud CG.

Curr Biol. 2019 Mar 4;29(5):737-749.e5. doi: 10.1016/j.cub.2019.01.029. Epub 2019 Feb 14.

PMID:
30773367
6.

Atypical cannabinoid ligands O-1602 and O-1918 administered chronically in diet-induced obesity.

Simcocks AC, Jenkin KA, O'Keefe L, Samuel CS, Mathai ML, McAinch AJ, Hryciw DH.

Endocr Connect. 2019 Mar 1;8(3):203-216. doi: 10.1530/EC-18-0535.

7.

Successfully Incorporating Interprofessional Education in a Nonacademic Health Sciences Center.

O'Keefe LC, Lioce L, Benton A, Morgan T, Adams MH.

Nurs Educ Perspect. 2018 Nov 7. doi: 10.1097/01.NEP.0000000000000416. [Epub ahead of print]

PMID:
30407985
8.

ACE I/D gene variant predicts ACE enzyme content in blood but not the ACE, UCP2, and UCP3 protein content in human skeletal muscle in the Gene SMART study.

Yan X, Dvir N, Jacques M, Cavalcante L, Papadimitriou ID, Munson F, Kuang J, Garnham A, Landen S, Li J, O'Keefe L, Tirosh O, Bishop DJ, Voisin S, Eynon N.

J Appl Physiol (1985). 2018 Sep 1;125(3):923-930. doi: 10.1152/japplphysiol.00344.2018. Epub 2018 Jun 21.

PMID:
29927735
9.

Using Drosophila Models of Amyloid Toxicity to Study Autophagy in the Pathogenesis of Alzheimer's Disease.

O'Keefe L, Denton D.

Biomed Res Int. 2018 May 20;2018:5195416. doi: 10.1155/2018/5195416. eCollection 2018. Review.

10.

Neuronal-specific impairment of heparan sulfate degradation in Drosophila reveals pathogenic mechanisms for Mucopolysaccharidosis type IIIA.

Webber DL, Choo A, Hewson LJ, Trim PJ, Snel MF, Hopwood JJ, Richards RI, Hemsley KM, O'Keefe LV.

Exp Neurol. 2018 May;303:38-47. doi: 10.1016/j.expneurol.2018.01.020. Epub 2018 Feb 2.

PMID:
29408731
11.

Commentary on "Comparison of Hand Function Between Children With Type 1 Diabetes Mellitus and Children Without Type 1 Diabetes Mellitus".

Hall CA, OʼKeefe LM.

Pediatr Phys Ther. 2018 Jan;30(1):66. doi: 10.1097/PEP.0000000000000472. No abstract available.

PMID:
29252841
12.

The gene SMART study: method, study design, and preliminary findings.

Yan X, Eynon N, Papadimitriou ID, Kuang J, Munson F, Tirosh O, O'Keefe L, Griffiths LR, Ashton KJ, Byrne N, Pitsiladis YP, Bishop DJ.

BMC Genomics. 2017 Nov 14;18(Suppl 8):821. doi: 10.1186/s12864-017-4186-4. Review.

13.

Providers' Attitudes and Knowledge of Lesbian, Gay, Bisexual, and Transgender Health.

Rowe D, Ng YC, O'Keefe L, Crawford D.

Fed Pract. 2017 Nov;34(11):28-34.

14.

Better together: Simultaneous presentation of speech and gesture in math instruction supports generalization and retention.

Congdon EL, Novack MA, Brooks N, Hemani-Lopez N, O'Keefe L, Goldin-Meadow S.

Learn Instr. 2017 Aug;50:65-74. doi: 10.1016/j.learninstruc.2017.03.005. Epub 2017 Apr 7.

15.

Screening for Colorectal Cancer at the Worksite.

O'Keefe LC, Sullivan MM, McPhail A, Van Buren K, Dewberry N.

Workplace Health Saf. 2018 Apr;66(4):183-190. doi: 10.1177/2165079917733483. Epub 2017 Oct 11.

PMID:
29020876
16.

Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma.

Pectasides E, Stachler MD, Derks S, Liu Y, Maron S, Islam M, Alpert L, Kwak H, Kindler H, Polite B, Sharma MR, Allen K, O'Day E, Lomnicki S, Maranto M, Kanteti R, Fitzpatrick C, Weber C, Setia N, Xiao SY, Hart J, Nagy RJ, Kim KM, Choi MG, Min BH, Nason KS, O'Keefe L, Watanabe M, Baba H, Lanman R, Agoston AT, Oh DJ, Dunford A, Thorner AR, Ducar MD, Wollison BM, Coleman HA, Ji Y, Posner MC, Roggin K, Turaga K, Chang P, Hogarth K, Siddiqui U, Gelrud A, Ha G, Freeman SS, Rhoades J, Reed S, Gydush G, Rotem D, Davison J, Imamura Y, Adalsteinsson V, Lee J, Bass AJ, Catenacci DV.

Cancer Discov. 2018 Jan;8(1):37-48. doi: 10.1158/2159-8290.CD-17-0395. Epub 2017 Oct 4.

17.

The SCHEIE Visual Field Grading System.

Sankar PS, O'Keefe L, Choi D, Salowe R, Miller-Ellis E, Lehman A, Addis V, Ramakrishnan M, Natesh V, Whitehead G, Khachatryan N, O'Brien J.

J Clin Exp Ophthalmol. 2017 Jun;8(3). pii: 651. doi: 10.4172/2155-9570.1000651. Epub 2017 May 11.

18.

Cost and yield considerations when expanding recruitment for genetic studies: the primary open-angle African American glaucoma genetics study.

Salowe R, O'Keefe L, Merriam S, Lee R, Khachatryan N, Sankar P, Miller-Ellis E, Lehman A, Addis V, Murphy W, Henderer J, Maguire M, O'Brien J.

BMC Med Res Methodol. 2017 Jul 14;17(1):101. doi: 10.1186/s12874-017-0374-9.

19.

Factors associated with participation by African Americans in a study of the genetics of glaucoma.

Parikh R, O'Keefe L, Salowe R, Mccoskey M, Pan W, Sankar P, Miller-Ellis E, Addis V, Lehman A, Maguire M, O'Brien J.

Ethn Health. 2019 Aug;24(6):694-704. doi: 10.1080/13557858.2017.1346189. Epub 2017 Jul 1.

PMID:
28669230
20.

The Inherent Challenges of Using Large Data Sets in Healthcare Research: Experiences of an Interdisciplinary Team.

Kaulfus A, Alexander S, Zhao S, Oster RA, OʼKeefe LC, Bartolucci A.

Comput Inform Nurs. 2017 May;35(5):221-225. doi: 10.1097/CIN.0000000000000359. No abstract available.

21.

Attenuation of Resting but Not Load-Mediated Protein Synthesis in Prostate Cancer Patients on Androgen Deprivation.

Hanson ED, Nelson AR, West DW, Violet JA, O'Keefe L, Phillips SM, Hayes A.

J Clin Endocrinol Metab. 2017 Mar 1;102(3):1076-1083. doi: 10.1210/jc.2016-3383.

PMID:
28359098
22.

Leadership Initiatives in Patient-Centered Transgender Care.

Rowe D, Ng YC, O'Keefe L.

Fed Pract. 2017 Jan;34(1):8-14.

23.

Nurse faculty as international research collaborators.

O'Keefe LC, Frith KH, Barnby E.

Nurs Health Sci. 2017 Mar;19(1):119-125. doi: 10.1111/nhs.12312. Epub 2016 Oct 26.

PMID:
27781360
24.

The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism of Neurodegenerative Disease.

Richards RI, Robertson SA, O'Keefe LV, Fornarino D, Scott A, Lardelli M, Baune BT.

Front Neurosci. 2016 May 10;10:193. doi: 10.3389/fnins.2016.00193. eCollection 2016.

25.

Obesity, Prediabetes, and Perceived Stress in Municipal Workers.

O'Keefe LC, Brown KC, Frith KH, Heaton KL, Maples EH, Phillips JA, Vance DE.

Workplace Health Saf. 2016 Oct;64(10):453-461. doi: 10.1177/2165079916632771. Epub 2016 Jul 10.

PMID:
27026274
26.

Ebola Update.

O'Keefe LC.

Workplace Health Saf. 2016 Jan;64(1):13-6. doi: 10.1177/2165079915607496. Epub 2015 Sep 29.

PMID:
26419541
27.

Middle East Respiratory Syndrome Coronavirus.

O'Keefe LC.

Workplace Health Saf. 2016 May;64(5):184-6. doi: 10.1177/2165079915607497. Epub 2015 Sep 25.

PMID:
26407596
28.

Tumor suppressor WWOX moderates the mitochondrial respiratory complex.

Choo A, O'Keefe LV, Lee CS, Gregory SL, Shaukat Z, Colella A, Lee K, Denton D, Richards RI.

Genes Chromosomes Cancer. 2015 Dec;54(12):745-61. doi: 10.1002/gcc.22286. Epub 2015 Sep 22.

PMID:
26390919
29.

Tumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogaster.

O'Keefe LV, Lee CS, Choo A, Richards RI.

PLoS One. 2015 Aug 24;10(8):e0136356. doi: 10.1371/journal.pone.0136356. eCollection 2015.

30.

Promoting Best Practices for Managing Acute Low Back Pain in an Occupational Environment.

Slaughter AL, Frith K, O'Keefe L, Alexander S, Stoll R.

Workplace Health Saf. 2015 Sep;63(9):408-14; quiz 415. doi: 10.1177/2165079915589034.

PMID:
26290452
31.

Thyroid hormones and functional outcomes after ischemic stroke.

O'Keefe LM, Conway SE, Czap A, Malchoff CD, Benashski S, Fortunato G, Staff I, McCullough LD.

Thyroid Res. 2015 Jul 4;8:9. doi: 10.1186/s13044-015-0021-7. eCollection 2015.

32.

Practical guidance on the recognition of uncontrolled asthma and its management.

Hoy HM, O'Keefe LC.

J Am Assoc Nurse Pract. 2015 Aug;27(8):466-75. doi: 10.1002/2327-6924.12284. Epub 2015 Jun 25.

PMID:
26119777
33.

Chronic administration of AM251 improves albuminuria and renal tubular structure in obese rats.

Jenkin KA, O'Keefe L, Simcocks AC, Grinfeld E, Mathai ML, McAinch AJ, Hryciw DH.

J Endocrinol. 2015 May;225(2):113-24. doi: 10.1530/JOE-15-0004. Epub 2015 Mar 24.

PMID:
25804605
34.

WWOX, the chromosomal fragile site FRA16D spanning gene: its role in metabolism and contribution to cancer.

Richards RI, Choo A, Lee CS, Dayan S, O'Keefe L.

Exp Biol Med (Maywood). 2015 Mar;240(3):338-44. doi: 10.1177/1535370214565990. Epub 2015 Jan 16. Review.

35.

Renal effects of chronic pharmacological manipulation of CB2 receptors in rats with diet-induced obesity.

Jenkin KA, O'Keefe L, Simcocks AC, Briffa JF, Mathai ML, McAinch AJ, Hryciw DH.

Br J Pharmacol. 2016 Apr;173(7):1128-42. doi: 10.1111/bph.13056. Epub 2015 Feb 27.

36.

Chromosomal instability causes sensitivity to metabolic stress.

Shaukat Z, Liu D, Choo A, Hussain R, O'Keefe L, Richards R, Saint R, Gregory SL.

Oncogene. 2015 Jul 30;34(31):4044-55. doi: 10.1038/onc.2014.344. Epub 2014 Oct 27.

PMID:
25347746
37.

Inhibition of mitochondrial p53 abolishes the detrimental effects of social isolation on ischemic brain injury.

Venna VR, Verma R, O'Keefe LM, Xu Y, Crapser J, Friedler B, McCullough LD.

Stroke. 2014 Oct;45(10):3101-4. doi: 10.1161/STROKEAHA.114.006553. Epub 2014 Sep 9.

38.

Policy perspectives on occupational stress.

O'Keefe LC, Brown KC, Christian BJ.

Workplace Health Saf. 2014 Oct;62(10):432-8; quiz 439. doi: 10.3928/21650799-20140813-02. Epub 2014 Aug 20. Review.

PMID:
25139784
39.

Association between efavirenz as initial therapy for HIV-1 infection and increased risk for suicidal ideation or attempted or completed suicide: an analysis of trial data.

Mollan KR, Smurzynski M, Eron JJ, Daar ES, Campbell TB, Sax PE, Gulick RM, Na L, O'Keefe L, Robertson KR, Tierney C.

Ann Intern Med. 2014 Jul 1;161(1):1-10. doi: 10.7326/M14-0293. Erratum in: Ann Intern Med. 2014 Aug 19;161(4):308.

40.

A potential role for GPR55 in the regulation of energy homeostasis.

Simcocks AC, O'Keefe L, Jenkin KA, Mathai ML, Hryciw DH, McAinch AJ.

Drug Discov Today. 2014 Aug;19(8):1145-51. doi: 10.1016/j.drudis.2013.12.005. Epub 2013 Dec 24. Review.

PMID:
24370891
41.

Social isolation after stroke leads to depressive-like behavior and decreased BDNF levels in mice.

O'Keefe LM, Doran SJ, Mwilambwe-Tshilobo L, Conti LH, Venna VR, McCullough LD.

Behav Brain Res. 2014 Mar 1;260:162-70. doi: 10.1016/j.bbr.2013.10.047. Epub 2013 Nov 5.

42.

RNA pathogenesis via Toll-like receptor-activated inflammation in expanded repeat neurodegenerative diseases.

Richards RI, Samaraweera SE, van Eyk CL, O'Keefe LV, Suter CM.

Front Mol Neurosci. 2013 Sep 5;6:25. doi: 10.3389/fnmol.2013.00025. eCollection 2013.

43.

The cannabinoid receptor 1 and its role in influencing peripheral metabolism.

O'Keefe L, Simcocks AC, Hryciw DH, Mathai ML, McAinch AJ.

Diabetes Obes Metab. 2014 Apr;16(4):294-304. doi: 10.1111/dom.12144. Epub 2013 Jul 10. Review.

PMID:
23782485
44.

Common chromosomal fragile site FRA16D tumor suppressor WWOX gene expression and metabolic reprograming in cells.

Dayan S, O'Keefe LV, Choo A, Richards RI.

Genes Chromosomes Cancer. 2013 Sep;52(9):823-31. doi: 10.1002/gcc.22078. Epub 2013 Jun 13.

PMID:
23765596
45.

Modeling and analysis of repeat RNA toxicity in Drosophila.

Samaraweera SE, O'Keefe LV, van Eyk CL, Lawlor KT, Humphreys DT, Suter CM, Richards RI.

Methods Mol Biol. 2013;1017:173-92. doi: 10.1007/978-1-62703-438-8_13.

PMID:
23719916
46.

Distinct roles for Toll and autophagy pathways in double-stranded RNA toxicity in a Drosophila model of expanded repeat neurodegenerative diseases.

Samaraweera SE, O'Keefe LV, Price GR, Venter DJ, Richards RI.

Hum Mol Genet. 2013 Jul 15;22(14):2811-9. doi: 10.1093/hmg/ddt130. Epub 2013 Mar 21.

47.

Ubiquitous expression of CUG or CAG trinucleotide repeat RNA causes common morphological defects in a Drosophila model of RNA-mediated pathology.

Lawlor KT, O'Keefe LV, Samaraweera SE, van Eyk CL, Richards RI.

PLoS One. 2012;7(6):e38516. doi: 10.1371/journal.pone.0038516. Epub 2012 Jun 8.

48.

Comparative toxicity of polyglutamine, polyalanine and polyleucine tracts in Drosophila models of expanded repeat disease.

van Eyk CL, McLeod CJ, O'Keefe LV, Richards RI.

Hum Mol Genet. 2012 Feb 1;21(3):536-47. doi: 10.1093/hmg/ddr487. Epub 2011 Oct 21.

PMID:
22021427
49.

Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases.

Lawlor KT, O'Keefe LV, Samaraweera SE, van Eyk CL, McLeod CJ, Maloney CA, Dang TH, Suter CM, Richards RI.

Hum Mol Genet. 2011 Oct 1;20(19):3757-68. doi: 10.1093/hmg/ddr292. Epub 2011 Jun 30.

PMID:
21724553
50.

Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

van Eyk CL, O'Keefe LV, Lawlor KT, Samaraweera SE, McLeod CJ, Price GR, Venter DJ, Richards RI.

Hum Mol Genet. 2011 Jul 15;20(14):2783-94. doi: 10.1093/hmg/ddr177. Epub 2011 Apr 25.

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