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Body composition in heart failure and the impact of cardiac resynchronisation therapy: a proof-of-concept study.

McAloon CJ, Hyndman S, Ansell V, O'Hare P, Randeva H, Osman F.

Open Heart. 2020 Feb 19;7(1):e001105. doi: 10.1136/openhrt-2019-001105. eCollection 2020.


Analysis of a fully infectious bio-orthogonally modified human virus reveals novel features of virus cell entry.

Serwa RA, Sekine E, Brown J, Teo SHC, Tate EW, O'Hare P.

PLoS Pathog. 2019 Oct 7;15(10):e1007956. doi: 10.1371/journal.ppat.1007956. eCollection 2019 Oct.


Effect of submucosal dexamethasone injections in the prevention of postoperative pain, trismus, and oedema associated with mandibular third molar surgery: a systematic review and meta-analysis.

O'Hare PE, Wilson BJ, Loga MG, Ariyawardana A.

Int J Oral Maxillofac Surg. 2019 Nov;48(11):1456-1469. doi: 10.1016/j.ijom.2019.04.010. Epub 2019 May 9.


Multiradionuclide evidence for an extreme solar proton event around 2,610 B.P. (∼660 BC).

O'Hare P, Mekhaldi F, Adolphi F, Raisbeck G, Aldahan A, Anderberg E, Beer J, Christl M, Fahrni S, Synal HA, Park J, Possnert G, Southon J, Bard E; ASTER Team, Muscheler R.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):5961-5966. doi: 10.1073/pnas.1815725116. Epub 2019 Mar 11.


Characterisation of circulating biomarkers before and after cardiac resynchronisation therapy and their role in predicting CRT response: the COVERT-HF study.

McAloon CJ, Barwari T, Hu J, Hamborg T, Nevill A, Hyndman S, Ansell V, Musa A, Jones J, Goodby J, Banerjee P, O'Hare P, Mayr M, Randeva H, Osman F.

Open Heart. 2018 Oct 18;5(2):e000899. doi: 10.1136/openhrt-2018-000899. eCollection 2018.


Human TANK-binding kinase 1 is required for early autophagy induction upon herpes simplex virus 1 infection.

Ahmad L, Mashbat B, Leung C, Brookes C, Hamad S, Krokowski S, Shenoy AR, Lorenzo L, Levin M, O'Hare P, Zhang SY, Casanova JL, Mostowy S, Sancho-Shimizu V.

J Allergy Clin Immunol. 2019 Feb;143(2):765-769.e7. doi: 10.1016/j.jaci.2018.09.013. Epub 2018 Oct 5. No abstract available.


A bimodal switch in global protein translation coupled to eIF4H relocalisation during advancing cell-cell transmission of herpes simplex virus.

Teo CSH, O'Hare P.

PLoS Pathog. 2018 Jul 20;14(7):e1007196. doi: 10.1371/journal.ppat.1007196. eCollection 2018 Jul.


Chemotherapy-Induced Tunneling Nanotubes Mediate Intercellular Drug Efflux in Pancreatic Cancer.

Desir S, O'Hare P, Vogel RI, Sperduto W, Sarkari A, Dickson EL, Wong P, Nelson AC, Fong Y, Steer CJ, Subramanian S, Lou E.

Sci Rep. 2018 Jun 21;8(1):9484. doi: 10.1038/s41598-018-27649-x.


Delineation of the visual pathway in paediatric optic pathway glioma patients using probabilistic tractography, and correlations with visual acuity.

Hales PW, Smith V, Dhanoa-Hayre D, O'Hare P, Mankad K, d'Arco F, Cooper J, Kaur R, Phipps K, Bowman R, Hargrave D, Clark C.

Neuroimage Clin. 2017 Oct 11;17:541-548. doi: 10.1016/j.nicl.2017.10.010. eCollection 2018.


Volumetric assessment of tumor size changes in pediatric low-grade gliomas: feasibility and comparison with linear measurements.

D'Arco F, O'Hare P, Dashti F, Lassaletta A, Loka T, Tabori U, Talenti G, Thust S, Messalli G, Hales P, Bouffet E, Laughlin S.

Neuroradiology. 2018 Apr;60(4):427-436. doi: 10.1007/s00234-018-1979-3. Epub 2018 Jan 30.


A transwell assay that excludes exosomes for assessment of tunneling nanotube-mediated intercellular communication.

Thayanithy V, O'Hare P, Wong P, Zhao X, Steer CJ, Subramanian S, Lou E.

Cell Commun Signal. 2017 Nov 13;15(1):46. doi: 10.1186/s12964-017-0201-2.


Spatiotemporal dynamics of HSV genome nuclear entry and compaction state transitions using bioorthogonal chemistry and super-resolution microscopy.

Sekine E, Schmidt N, Gaboriau D, O'Hare P.

PLoS Pathog. 2017 Nov 9;13(11):e1006721. doi: 10.1371/journal.ppat.1006721. eCollection 2017 Nov.


Extracellular cardiac matrix biomarkers in patients with reduced ejection fraction heart failure as predictors of response to cardiac resynchronisation therapy: a systematic review.

McAloon CJ, Ali D, Hamborg T, Banerjee P, O'Hare P, Randeva H, Osman F.

Open Heart. 2017 Aug 21;4(2):e000639. doi: 10.1136/openhrt-2017-000639. eCollection 2017. Review.


Guidelines for type 2 diabetes: keeping a finger on the pulse.

Barnett AH, O'Hare P, Halcox J.

Lancet Diabetes Endocrinol. 2017 Jun;5(6):420. doi: 10.1016/S2213-8587(17)30136-5. Epub 2017 Apr 19. No abstract available.


GSK-3-mediated phosphorylation couples ER-Golgi transport and nuclear stabilization of the CREB-H transcription factor to mediate apolipoprotein secretion.

Barbosa S, Carreira S, O'Hare P.

Mol Biol Cell. 2017 Jun 1;28(11):1565-1579. doi: 10.1091/mbc.E17-01-0075. Epub 2017 Apr 5.


MEK inhibition appears to improve symptom control in primary NRAS-driven CNS melanoma in children.

Kinsler VA, O'Hare P, Jacques T, Hargrave D, Slater O.

Br J Cancer. 2017 Apr 11;116(8):990-993. doi: 10.1038/bjc.2017.49. Epub 2017 Mar 2.


Allogeneic stem cell transplantation for refractory acute myeloid leukemia in pediatric patients: the UK experience.

O'Hare P, Lucchini G, Cummins M, Veys P, Potter M, Lawson S, Vora A, Wynn R, Peniket A, Kirkland K, Pearce R, Perry J, Amrolia PJ.

Bone Marrow Transplant. 2017 Jun;52(6):825-831. doi: 10.1038/bmt.2017.3. Epub 2017 Feb 20.


Melanoma in congenital melanocytic naevi.

Kinsler VA, O'Hare P, Bulstrode N, Calonje JE, Chong WK, Hargrave D, Jacques T, Lomas D, Sebire NJ, Slater O.

Br J Dermatol. 2017 May;176(5):1131-1143. doi: 10.1111/bjd.15301. Epub 2017 Apr 4. Review.


Lost in translation: applying 2D intercellular communication via tunneling nanotubes in cell culture to physiologically relevant 3D microenvironments.

Lou E, O'Hare P, Subramanian S, Steer CJ.

FEBS J. 2017 Mar;284(5):699-707. doi: 10.1111/febs.13946. Epub 2016 Nov 30. Review.


Spatial and Temporal Resolution of Global Protein Synthesis during HSV Infection Using Bioorthogonal Precursors and Click Chemistry.

Su Hui Teo C, Serwa RA, O'Hare P.

PLoS Pathog. 2016 Oct 5;12(10):e1005927. doi: 10.1371/journal.ppat.1005927. eCollection 2016 Oct.


The interplay between heart failure, metabolism and body composition.

McAloon CJ, O'Hare P, Osman F, Randeva HS.

Br J Hosp Med (Lond). 2016 Jun;77(6):362-4. doi: 10.12968/hmed.2016.77.6.362. Review.


Remote Activation of Host Cell DNA Synthesis in Uninfected Cells Signaled by Infected Cells in Advance of Virus Transmission.

Schmidt N, Hennig T, Serwa RA, Marchetti M, O'Hare P.

J Virol. 2015 Nov;89(21):11107-15. doi: 10.1128/JVI.01950-15. Epub 2015 Aug 26.


Systems Analysis of Protein Fatty Acylation in Herpes Simplex Virus-Infected Cells Using Chemical Proteomics.

Serwa RA, Abaitua F, Krause E, Tate EW, O'Hare P.

Chem Biol. 2015 Aug 20;22(8):1008-17. doi: 10.1016/j.chembiol.2015.06.024. Epub 2015 Aug 6.


An investigation of thrust, depth and the impedance cardiogram as measures of cardiopulmonary resuscitation efficacy in a porcine model of cardiac arrest.

Howe A, O'Hare P, Crawford P, Delafont B, McAlister O, Di Maio R, Clutton E, Adgey J, McEneaney D.

Resuscitation. 2015 Nov;96:114-20. doi: 10.1016/j.resuscitation.2015.07.020. Epub 2015 Jul 31.


Viruses and the nuclear envelope.

Hennig T, O'Hare P.

Curr Opin Cell Biol. 2015 Jun;34:113-21. doi: 10.1016/ Epub 2015 Jun 28. Review.


Childhood and Adolescent nodular lymphocyte predominant Hodgkin lymphoma - A review of clinical outcome based on the histological variants.

Shankar AG, Kirkwood AA, Hall GW, Hayward J, O'Hare P, Ramsay AD.

Br J Haematol. 2015 Oct;171(2):254-262. doi: 10.1111/bjh.13540. Epub 2015 Jun 26.


Phosphorylation and SCF-mediated degradation regulate CREB-H transcription of metabolic targets.

Barbosa S, Carreira S, Bailey D, Abaitua F, O'Hare P.

Mol Biol Cell. 2015 Aug 15;26(16):2939-54. doi: 10.1091/mbc.E15-04-0247. Epub 2015 Jun 24.


Botulinum Toxin A Injections Into Pelvic Floor Muscles Under Electromyographic Guidance for Women With Refractory High-Tone Pelvic Floor Dysfunction: A 6-Month Prospective Pilot Study.

Morrissey D, El-Khawand D, Ginzburg N, Wehbe S, O'Hare P 3rd, Whitmore K.

Female Pelvic Med Reconstr Surg. 2015 Sep-Oct;21(5):277-82. doi: 10.1097/SPV.0000000000000177.


Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.

Sun C, Schattgen SA, Pisitkun P, Jorgensen JP, Hilterbrand AT, Wang LJ, West JA, Hansen K, Horan KA, Jakobsen MR, O'Hare P, Adler H, Sun R, Ploegh HL, Damania B, Upton JW, Fitzgerald KA, Paludan SR.

J Immunol. 2015 Feb 15;194(4):1819-31. doi: 10.4049/jimmunol.1402495. Epub 2015 Jan 16.


Attitudes, access and anguish: a qualitative interview study of staff and patients' experiences of diabetic retinopathy screening.

Hipwell AE, Sturt J, Lindenmeyer A, Stratton I, Gadsby R, O'Hare P, Scanlon PH.

BMJ Open. 2014 Dec 15;4(12):e005498. doi: 10.1136/bmjopen-2014-005498.


Biomarkers of progression of chronic obstructive pulmonary disease (COPD).

Shaw JG, Vaughan A, Dent AG, O'Hare PE, Goh F, Bowman RV, Fong KM, Yang IA.

J Thorac Dis. 2014 Nov;6(11):1532-47. doi: 10.3978/j.issn.2072-1439.2014.11.33. Review.


Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation.

Zaborowska J, Baumli S, Laitem C, O'Reilly D, Thomas PH, O'Hare P, Murphy S.

PLoS One. 2014 Sep 18;9(9):e107654. doi: 10.1371/journal.pone.0107654. eCollection 2014.


Risk factors for vaginal mesh exposure after mesh-augmented anterior repair: a retrospective cohort study.

El-Khawand D, Wehbe SA, O'Hare PG 3rd, Arunachalam D, Vakili B.

Female Pelvic Med Reconstr Surg. 2014 Nov-Dec;20(6):305-9. doi: 10.1097/SPV.0000000000000095.


Coronary artery calcification on computed tomography correlates with mortality in chronic obstructive pulmonary disease.

OʼHare PE, Ayres JF, OʼRourke RL, Slaughter RE, Marshall HM, Bowman RV, Fong KM, Yang IA.

J Comput Assist Tomogr. 2014 Sep-Oct;38(5):753-9. doi: 10.1097/RCT.0000000000000119.


Functional analysis of nuclear localization signals in VP1-2 homologues from all herpesvirus subfamilies.

Hennig T, Abaitua F, O'Hare P.

J Virol. 2014 May;88(10):5391-405. doi: 10.1128/JVI.03797-13. Epub 2014 Feb 26.


Personalizing and targeting therapy for COPD: the role of molecular and clinical biomarkers.

Goh F, Shaw JG, Savarimuthu Francis SM, Vaughan A, Morrison L, Relan V, Marshall HM, Dent AG, O'Hare PE, Hsiao A, Bowman RV, Fong KM, Yang IA.

Expert Rev Respir Med. 2013 Dec;7(6):593-605. doi: 10.1586/17476348.2013.842468. Epub 2013 Oct 28. Review.


The influence of target stoichiometry on early cell adhesion of co-sputtered calcium-phosphate surfaces.

Boyd AR, O'Kane C, O'Hare P, Burke GA, Meenan BJ.

J Mater Sci Mater Med. 2013 Dec;24(12):2845-61. doi: 10.1007/s10856-013-5021-3. Epub 2013 Aug 7.


Cardiovascular benefits of incretins.

Barnett AH, O'Hare P.

BMJ. 2013 Jul 10;347:f4382. doi: 10.1136/bmj.f4382. No abstract available.


Polarized cell migration during cell-to-cell transmission of herpes simplex virus in human skin keratinocytes.

Abaitua F, Zia FR, Hollinshead M, O'Hare P.

J Virol. 2013 Jul;87(14):7921-32. doi: 10.1128/JVI.01172-13. Epub 2013 May 8.


An orchestrated program regulating secretory pathway genes and cargos by the transmembrane transcription factor CREB-H.

Barbosa S, Fasanella G, Carreira S, Llarena M, Fox R, Barreca C, Andrew D, O'Hare P.

Traffic. 2013 Apr;14(4):382-98. doi: 10.1111/tra.12038. Epub 2013 Jan 24.


Interstitial cystitis patients' use and rating of complementary and alternative medicine therapies.

O'Hare PG 3rd, Hoffmann AR, Allen P, Gordon B, Salin L, Whitmore K.

Int Urogynecol J. 2013 Jun;24(6):977-82. doi: 10.1007/s00192-012-1966-x. Epub 2012 Nov 14.


A Nuclear localization signal in herpesvirus protein VP1-2 is essential for infection via capsid routing to the nuclear pore.

Abaitua F, Hollinshead M, Bolstad M, Crump CM, O'Hare P.

J Virol. 2012 Sep;86(17):8998-9014. doi: 10.1128/JVI.01209-12. Epub 2012 Jun 20.


Fatigue and biocompatibility properties of a poly(methyl methacrylate) bone cement with multi-walled carbon nanotubes.

Ormsby R, McNally T, O'Hare P, Burke G, Mitchell C, Dunne N.

Acta Biomater. 2012 Mar;8(3):1201-12. doi: 10.1016/j.actbio.2011.10.010. Epub 2011 Oct 13.


Autocatalytic activity of the ubiquitin-specific protease domain of herpes simplex virus 1 VP1-2.

Bolstad M, Abaitua F, Crump CM, O'Hare P.

J Virol. 2011 Sep;85(17):8738-51. doi: 10.1128/JVI.00798-11. Epub 2011 Jun 29.


Comparative in vitro cytotoxicity study of carbon nanotubes and titania nanostructures on human lung epithelial cells.

Wadhwa S, Rea C, O'Hare P, Mathur A, Roy SS, Dunlop PS, Byrne JA, Burke G, Meenan B, McLaughlin JA.

J Hazard Mater. 2011 Jul 15;191(1-3):56-61. doi: 10.1016/j.jhazmat.2011.04.035. Epub 2011 Apr 16.


Raman spectroscopic monitoring of the osteogenic differentiation of human mesenchymal stem cells.

McManus LL, Burke GA, McCafferty MM, O'Hare P, Modreanu M, Boyd AR, Meenan BJ.

Analyst. 2011 Jun 21;136(12):2471-81. doi: 10.1039/c1an15167c. Epub 2011 May 4.


A single mutation responsible for temperature-sensitive entry and assembly defects in the VP1-2 protein of herpes simplex virus.

Abaitua F, Daikoku T, Crump CM, Bolstad M, O'Hare P.

J Virol. 2011 Mar;85(5):2024-36. doi: 10.1128/JVI.01895-10. Epub 2010 Dec 22.


Deposition of substituted apatites with anticolonizing properties onto titanium surfaces using a novel blasting process.

O'Sullivan C, O'Hare P, O'Leary ND, Crean AM, Ryan K, Dobson AD, O'Neill L.

J Biomed Mater Res B Appl Biomater. 2010 Oct;95(1):141-9. doi: 10.1002/jbm.b.31694.


Harm reduction: moving through the third decade.

Stimson GV, O'Hare P.

Int J Drug Policy. 2010 Mar;21(2):91-3. doi: 10.1016/j.drugpo.2010.02.002. Epub 2010 Feb 18. No abstract available.


Different mechanisms of recognition and ER retention by transmembrane transcription factors CREB-H and ATF6.

Llarena M, Bailey D, Curtis H, O'Hare P.

Traffic. 2010 Jan;11(1):48-69. doi: 10.1111/j.1600-0854.2009.00997.x.

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