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Items: 1 to 50 of 143

1.

Sirolimus as treatment for 19 patients with refractory cervicofacial lymphatic malformation.

Strychowsky JE, Rahbar R, O'Hare MJ, Irace AL, Padua H, Trenor CC 3rd.

Laryngoscope. 2018 Jan;128(1):269-276. doi: 10.1002/lary.26780. Epub 2017 Aug 7.

PMID:
28782106
2.

Regulation of ischemic neuronal death by E2F4-p130 protein complexes.

Iyirhiaro GO, Zhang Y, Estey C, O'Hare MJ, Safarpour F, Parsanejad M, Wang S, Abdel-Messih E, Callaghan SM, During MJ, Slack RS, Park DS.

J Biol Chem. 2014 Jun 27;289(26):18202-13. doi: 10.1074/jbc.M114.574145. Epub 2014 May 14.

3.

The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene.

Chua YL, Ito Y, Pole JC, Newman S, Chin SF, Stein RC, Ellis IO, Caldas C, O'Hare MJ, Murrell A, Edwards PA.

Oncogene. 2009 Nov 19;28(46):4041-52. doi: 10.1038/onc.2009.259. Epub 2009 Oct 5.

4.

Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake.

Kemp SJ, Thorley AJ, Gorelik J, Seckl MJ, O'Hare MJ, Arcaro A, Korchev Y, Goldstraw P, Tetley TD.

Am J Respir Cell Mol Biol. 2008 Nov;39(5):591-7. doi: 10.1165/rcmb.2007-0334OC. Epub 2008 Jun 6.

5.

Hyperproliferation of PKD1 cystic cells is induced by insulin-like growth factor-1 activation of the Ras/Raf signalling system.

Parker E, Newby LJ, Sharpe CC, Rossetti S, Streets AJ, Harris PC, O'Hare MJ, Ong AC.

Kidney Int. 2007 Jul;72(2):157-65. Epub 2007 Mar 28.

6.

A conditionally immortalized cell line model for the study of human prostatic epithelial cell differentiation.

Daly-Burns B, Alam TN, Mackay A, Clark J, Shepherd CJ, Rizzo S, Tatoud R, O'Hare MJ, Masters JR, Hudson DL.

Differentiation. 2007 Jan;75(1):35-48.

PMID:
17244020
7.

Identification of transmembrane proteins as potential prognostic markers and therapeutic targets in breast cancer by a screen for signal sequence encoding transcripts.

Esseghir S, Reis-Filho JS, Kennedy A, James M, O'Hare MJ, Jeffery R, Poulsom R, Isacke CM.

J Pathol. 2006 Dec;210(4):420-30.

PMID:
17054309
8.

Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data.

Grigoriadis A, Mackay A, Reis-Filho JS, Steele D, Iseli C, Stevenson BJ, Jongeneel CV, Valgeirsson H, Fenwick K, Iravani M, Leao M, Simpson AJ, Strausberg RL, Jat PS, Ashworth A, Neville AM, O'Hare MJ.

Breast Cancer Res. 2006;8(5):R56.

9.

The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin.

Zhang Y, Qu D, Morris EJ, O'Hare MJ, Callaghan SM, Slack RS, Geller HM, Park DS.

J Neurosci. 2006 Aug 23;26(34):8819-28.

10.

Conditionally immortalized human glomerular endothelial cells expressing fenestrations in response to VEGF.

Satchell SC, Tasman CH, Singh A, Ni L, Geelen J, von Ruhland CJ, O'Hare MJ, Saleem MA, van den Heuvel LP, Mathieson PW.

Kidney Int. 2006 May;69(9):1633-40.

11.

Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death.

O'Hare MJ, Kushwaha N, Zhang Y, Aleyasin H, Callaghan SM, Slack RS, Albert PR, Vincent I, Park DS.

J Neurosci. 2005 Sep 28;25(39):8954-66.

12.

Tumour-stromal interactions in breast cancer: the role of stroma in tumourigenesis.

Kim JB, Stein R, O'Hare MJ.

Tumour Biol. 2005 Jul-Aug;26(4):173-85. Epub 2005 Jul 6. Review.

PMID:
16006771
13.

Heightened expression of CTCF in breast cancer cells is associated with resistance to apoptosis.

Docquier F, Farrar D, D'Arcy V, Chernukhin I, Robinson AF, Loukinov D, Vatolin S, Pack S, Mackay A, Harris RA, Dorricott H, O'Hare MJ, Lobanenkov V, Klenova E.

Cancer Res. 2005 Jun 15;65(12):5112-22.

14.

Transcriptional networks and cellular senescence in human mammary fibroblasts.

Hardy K, Mansfield L, Mackay A, Benvenuti S, Ismail S, Arora P, O'Hare MJ, Jat PS.

Mol Biol Cell. 2005 Feb;16(2):943-53. Epub 2004 Dec 1.

15.

Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype.

Clarke CL, Sandle J, Parry SC, Reis-Filho JS, O'Hare MJ, Lakhani SR.

J Pathol. 2004 Oct;204(2):147-52.

PMID:
15376255
16.

CDKs: taking on a role as mediators of dopaminergic loss in Parkinson's disease.

Smith PD, O'Hare MJ, Park DS.

Trends Mol Med. 2004 Sep;10(9):445-51. Review. No abstract available.

PMID:
15350897
17.

The expression of oestrogen receptor (ER)-beta and its variants, but not ERalpha, in adult human mammary fibroblasts.

Palmieri C, Saji S, Sakaguchi H, Cheng G, Sunters A, O'Hare MJ, Warner M, Gustafsson JA, Coombes RC, Lam EW.

J Mol Endocrinol. 2004 Aug;33(1):35-50.

PMID:
15291741
18.

Differential expression of CD44 during human prostate epithelial cell differentiation.

Alam TN, O'Hare MJ, Laczkó I, Freeman A, Al-Beidh F, Masters JR, Hudson DL.

J Histochem Cytochem. 2004 Aug;52(8):1083-90.

PMID:
15258184
19.

Order of genetic events is critical determinant of aberrations in chromosome count and structure.

Fauth C, O'Hare MJ, Lederer G, Jat PS, Speicher MR.

Genes Chromosomes Cancer. 2004 Aug;40(4):298-306.

PMID:
15188452
20.

Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer.

Jones C, Mackay A, Grigoriadis A, Cossu A, Reis-Filho JS, Fulford L, Dexter T, Davies S, Bulmer K, Ford E, Parry S, Budroni M, Palmieri G, Neville AM, O'Hare MJ, Lakhani SR.

Cancer Res. 2004 May 1;64(9):3037-45.

21.

Three-dimensional in vitro tissue culture models of breast cancer-- a review.

Kim JB, Stein R, O'Hare MJ.

Breast Cancer Res Treat. 2004 Jun;85(3):281-91. Review.

PMID:
15111767
22.

Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.

Aleyasin H, Cregan SP, Iyirhiaro G, O'Hare MJ, Callaghan SM, Slack RS, Park DS.

J Neurosci. 2004 Mar 24;24(12):2963-73.

23.

Emerging pathogenic role for cyclin dependent kinases in neurodegeneration.

Smith PD, O'Hare MJ, Park DS.

Cell Cycle. 2004 Mar;3(3):289-91. Epub 2004 Mar 1.

PMID:
14726693
24.

Models of breast cancer: is merging human and animal models the future?

Kim JB, O'Hare MJ, Stein R.

Breast Cancer Res. 2004;6(1):22-30. Epub 2003 Aug 19.

25.

Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease.

Smith PD, Crocker SJ, Jackson-Lewis V, Jordan-Sciutto KL, Hayley S, Mount MP, O'Hare MJ, Callaghan S, Slack RS, Przedborski S, Anisman H, Park DS.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13650-5. Epub 2003 Oct 31.

26.

The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags.

Brentani H, Caballero OL, Camargo AA, da Silva AM, da Silva WA Jr, Dias Neto E, Grivet M, Gruber A, Guimaraes PE, Hide W, Iseli C, Jongeneel CV, Kelso J, Nagai MA, Ojopi EP, Osorio EC, Reis EM, Riggins GJ, Simpson AJ, de Souza S, Stevenson BJ, Strausberg RL, Tajara EH, Verjovski-Almeida S, Acencio ML, Bengtson MH, Bettoni F, Bodmer WF, Briones MR, Camargo LP, Cavenee W, Cerutti JM, Coelho Andrade LE, Costa dos Santos PC, Ramos Costa MC, da Silva IT, Estécio MR, Sa Ferreira K, Furnari FB, Faria M Jr, Galante PA, Guimaraes GS, Holanda AJ, Kimura ET, Leerkes MR, Lu X, Maciel RM, Martins EA, Massirer KB, Melo AS, Mestriner CA, Miracca EC, Miranda LL, Nobrega FG, Oliveira PS, Paquola AC, Pandolfi JR, Campos Pardini MI, Passetti F, Quackenbush J, Schnabel B, Sogayar MC, Souza JE, Valentini SR, Zaiats AC, Amaral EJ, Arnaldi LA, de Araújo AG, de Bessa SA, Bicknell DC, Ribeiro de Camaro ME, Carraro DM, Carrer H, Carvalho AF, Colin C, Costa F, Curcio C, Guerreiro da Silva ID, Pereira da Silva N, Dellamano M, El-Dorry H, Espreafico EM, Scattone Ferreira AJ, Ayres Ferreira C, Fortes MA, Gama AH, Giannella-Neto D, Giannella ML, Giorgi RR, Goldman GH, Goldman MH, Hackel C, Ho PL, Kimura EM, Kowalski LP, Krieger JE, Leite LC, Lopes A, Luna AM, Mackay A, Mari SK, Marques AA, Martins WK, Montagnini A, Mourão Neto M, Nascimento AL, Neville AM, Nobrega MP, O'Hare MJ, Otsuka AY, Ruas de Melo AI, Paco-Larson ML, Guimarães Pereira G, Pereira da Silva N, Pesquero JB, Pessoa JG, Rahal P, Rainho CA, Rodrigues V, Rogatto SR, Romano CM, Romeiro JG, Rossi BM, Rusticci M, Guerra de Sá R, Sant' Anna SC, Sarmazo ML, Silva TC, Soares FA, Sonati Mde F, de Freitas Sousa J, Queiroz D, Valente V, Vettore AL, Villanova FE, Zago MA, Zalcberg H; Human Cancer Genome Project/Cancer Genome Anatomy Project Annotation Consortium; Human Cancer Genome Project Sequencing Consortium.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13418-23. Epub 2003 Oct 30.

27.

Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.

Adam PJ, Berry J, Loader JA, Tyson KL, Craggs G, Smith P, De Belin J, Steers G, Pezzella F, Sachsenmeir KF, Stamps AC, Herath A, Sim E, O'Hare MJ, Harris AL, Terrett JA.

Mol Cancer Res. 2003 Sep;1(11):826-35.

28.

Immortalisation of human ovarian surface epithelium with telomerase and temperature-sensitive SV40 large T antigen.

Davies BR, Steele IA, Edmondson RJ, Zwolinski SA, Saretzki G, von Zglinicki T, O'Hare MJ.

Exp Cell Res. 2003 Aug 15;288(2):390-402.

PMID:
12915130
29.

Functional analysis of PKD1 transgenic lines reveals a direct role for polycystin-1 in mediating cell-cell adhesion.

Streets AJ, Newby LJ, O'Hare MJ, Bukanov NO, Ibraghimov-Beskrovnaya O, Ong AC.

J Am Soc Nephrol. 2003 Jul;14(7):1804-15.

30.

Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression.

Scanlan MJ, Gout I, Gordon CM, Williamson B, Stockert E, Gure AO, Jäger D, Chen YT, Mackay A, O'Hare MJ, Old LJ.

Cancer Immun. 2001 Mar 30;1:4.

31.

cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells.

Mackay A, Jones C, Dexter T, Silva RL, Bulmer K, Jones A, Simpson P, Harris RA, Jat PS, Neville AM, Reis LF, Lakhani SR, O'Hare MJ.

Oncogene. 2003 May 1;22(17):2680-8.

PMID:
12730682
32.

Comprehensive sampling of gene expression in human cell lines with massively parallel signature sequencing.

Jongeneel CV, Iseli C, Stevenson BJ, Riggins GJ, Lal A, Mackay A, Harris RA, O'Hare MJ, Neville AM, Simpson AJ, Strausberg RL.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4702-5. Epub 2003 Apr 1.

33.

Regulation of breast cancer cell chemotaxis by the phosphoinositide 3-kinase p110delta.

Sawyer C, Sturge J, Bennett DC, O'Hare MJ, Allen WE, Bain J, Jones GE, Vanhaesebroeck B.

Cancer Res. 2003 Apr 1;63(7):1667-75.

34.

Cyclin-dependent kinases and stroke.

Wang F, O'Hare MJ, Park DS.

Expert Opin Ther Targets. 2001 Oct;5(5):557-567.

PMID:
12540283
35.
36.

The expression patterns of integrin subunits on human breast tissues obtained during pregnancy.

Suzuki RN, Entwistle A, Atherton AJ, Clarke C, Lakhani SR, O'Hare MJ.

Cell Biol Int. 2002;26(7):593-8.

PMID:
12127938
37.

Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor.

Gilmore AP, Valentijn AJ, Wang P, Ranger AM, Bundred N, O'Hare MJ, Wakeling A, Korsmeyer SJ, Streuli CH.

J Biol Chem. 2002 Aug 2;277(31):27643-50. Epub 2002 May 13.

38.

A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.

Saleem MA, O'Hare MJ, Reiser J, Coward RJ, Inward CD, Farren T, Xing CY, Ni L, Mathieson PW, Mundel P.

J Am Soc Nephrol. 2002 Mar;13(3):630-8.

39.

Cluster analysis of an extensive human breast cancer cell line protein expression map database.

Harris RA, Yang A, Stein RC, Lucy K, Brusten L, Herath A, Parekh R, Waterfield MD, O'Hare MJ, Neville MA, Page MJ, Zvelebil MJ.

Proteomics. 2002 Feb;2(2):212-23.

PMID:
11840567
40.

In silico comparison of the transcriptome derived from purified normal breast cells and breast tumor cell lines reveals candidate upregulated genes in breast tumor cells.

Leerkes MR, Caballero OL, Mackay A, Torloni H, O'Hare MJ, Simpson AJ, de Souza SJ.

Genomics. 2002 Feb;79(2):257-65.

PMID:
11829496
41.

The Use of Transgenic Animals in the European Union: The Report and Recommendations of ECVAM Workshop 28.

Mepham TB, Combes RD, Balls M, Barbieri O, Blokhuis HJ, Costa P, Crilly RE, de Cock Buning T, Delpire VC, O'Hare MJ, Houdebine LM, van Kreijl CF, van der Meer M, Reinhardt CA, Wolf E, van Zeller AM.

Altern Lab Anim. 1998 Jan-Feb;26(1):21-43. No abstract available.

PMID:
11656813
42.

Desmosomal adhesion regulates epithelial morphogenesis and cell positioning.

Runswick SK, O'Hare MJ, Jones L, Streuli CH, Garrod DR.

Nat Cell Biol. 2001 Sep;3(9):823-30.

PMID:
11533662
43.

Retroviral transduction of alveolar bone cells with a temperature-sensitive SV40 large T antigen.

Salih V, Knowles JC, O'Hare MJ, Olsen I.

Cell Tissue Res. 2001 Jun;304(3):371-6.

PMID:
11456413
44.

Immortalization of human hepatocytes by temperature-sensitive SV40 large-T antigen.

Smalley M, Leiper K, Tootle R, McCloskey P, O'Hare MJ, Hodgson H.

In Vitro Cell Dev Biol Anim. 2001 Mar;37(3):166-8. No abstract available.

PMID:
11370807
45.

Profiling familial breast cancer.

Lakhani SR, O'Hare MJ, Ashworth A.

Nat Med. 2001 Apr;7(4):408-10. No abstract available.

PMID:
11283660
46.

The mammary myoepithelial cell--Cinderella or ugly sister?

Lakhani SR, O'Hare MJ.

Breast Cancer Res. 2001;3(1):1-4. Epub 2000 Nov 2. Review.

47.

Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.

O'Hare MJ, Bond J, Clarke C, Takeuchi Y, Atherton AJ, Berry C, Moody J, Silver AR, Davies DC, Alsop AE, Neville AM, Jat PS.

Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):646-51.

48.

Epithelial cell differentiation pathways in the human prostate: identification of intermediate phenotypes by keratin expression.

Hudson DL, Guy AT, Fry P, O'Hare MJ, Watt FM, Masters JR.

J Histochem Cytochem. 2001 Feb;49(2):271-8.

PMID:
11156695
49.

Proliferation and differentiation in the human breast during pregnancy.

Suzuki R, Atherton AJ, O'Hare MJ, Entwistle A, Lakhani SR, Clarke C.

Differentiation. 2000 Oct;66(2-3):106-15.

PMID:
11100901
50.

Potential biological role of transforming growth factor-beta1 in human congenital kidney malformations.

Yang SP, Woolf AS, Yuan HT, Scott RJ, Risdon RA, O'Hare MJ, Winyard PJ.

Am J Pathol. 2000 Nov;157(5):1633-47.

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