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Items: 1 to 50 of 209

1.

The Microbiome of an Active Meat Curing Brine.

Woods DF, Kozak IM, Flynn S, O'Gara F.

Front Microbiol. 2019 Jan 11;9:3346. doi: 10.3389/fmicb.2018.03346. eCollection 2018.

2.

Genome Sequence of Paracoccus sp. JM45, a Bacterial Strain Isolated from a Marine Sponge with a Dual Quorum Sensing Inhibition Activity.

Gutiérrez-Barranquero JA, Parages ML, Dobson ADW, Reen FJ, O'Gara F.

Microbiol Resour Announc. 2019 Jan 10;8(2). pii: e01496-18. doi: 10.1128/MRA.01496-18. eCollection 2019 Jan.

3.

Transcutaneous Electrical Nerve Stimulation to Improve Female Sexual Dysfunction Symptoms: A Pilot Study.

Zimmerman LL, Gupta P, O'Gara F, Langhals NB, Berger MB, Bruns TM.

Neuromodulation. 2018 Oct;21(7):707-713. doi: 10.1111/ner.12846. Epub 2018 Sep 3.

PMID:
30247794
4.

Isoquercetin and inulin synergistically modulate the gut microbiome to prevent development of the metabolic syndrome in mice fed a high fat diet.

Tan S, Caparros-Martin JA, Matthews VB, Koch H, O'Gara F, Croft KD, Ward NC.

Sci Rep. 2018 Jul 4;8(1):10100. doi: 10.1038/s41598-018-28521-8.

5.

Harnessing Marine Biocatalytic Reservoirs for Green Chemistry Applications through Metagenomic Technologies.

Castilla IA, Woods DF, Reen FJ, O'Gara F.

Mar Drugs. 2018 Jul 4;16(7). pii: E227. doi: 10.3390/md16070227. Review.

6.

The expanding horizon of alkyl quinolone signalling and communication in polycellular interactomes.

Reen FJ, McGlacken GP, O'Gara F.

FEMS Microbiol Lett. 2018 May 1;365(9). doi: 10.1093/femsle/fny076.

PMID:
29718276
7.

Rethinking the bile acid/gut microbiome axis in cancer.

Phelan JP, Reen FJ, Caparros-Martin JA, O'Connor R, O'Gara F.

Oncotarget. 2017 Dec 1;8(70):115736-115747. doi: 10.18632/oncotarget.22803. eCollection 2017 Dec 29. Review.

8.

Rapid Electrochemical Detection of Pseudomonas aeruginosa Signaling Molecules by Boron-Doped Diamond Electrode.

Buzid A, Luong JHT, Reen FJ, O'Gara F, Glennon JD, McGlacken GP.

Methods Mol Biol. 2018;1673:107-116. doi: 10.1007/978-1-4939-7309-5_9.

PMID:
29130168
9.

Disruption of N-acyl-homoserine lactone-specific signalling and virulence in clinical pathogens by marine sponge bacteria.

Gutiérrez-Barranquero JA, Reen FJ, Parages ML, McCarthy R, Dobson ADW, O'Gara F.

Microb Biotechnol. 2017 Nov 3. doi: 10.1111/1751-7915.12867. [Epub ahead of print]

10.

Analogues of Pseudomonas aeruginosa signalling molecules to tackle infections.

Ó Muimhneacháin E, Reen FJ, O'Gara F, McGlacken GP.

Org Biomol Chem. 2018 Jan 3;16(2):169-179. doi: 10.1039/c7ob02395b. Review.

PMID:
29095463
11.

Identification of Secondary Metabolite Gene Clusters in the Pseudovibrio Genus Reveals Encouraging Biosynthetic Potential toward the Production of Novel Bioactive Compounds.

Naughton LM, Romano S, O'Gara F, Dobson ADW.

Front Microbiol. 2017 Aug 18;8:1494. doi: 10.3389/fmicb.2017.01494. eCollection 2017.

12.

Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism.

Caparrós-Martín JA, Lareu RR, Ramsay JP, Peplies J, Reen FJ, Headlam HA, Ward NC, Croft KD, Newsholme P, Hughes JD, O'Gara F.

Microbiome. 2017 Aug 9;5(1):95. doi: 10.1186/s40168-017-0312-4.

13.

Biotechnological Potential of Cold Adapted Pseudoalteromonas spp. Isolated from 'Deep Sea' Sponges.

Borchert E, Knobloch S, Dwyer E, Flynn S, Jackson SA, Jóhannsson R, Marteinsson VT, O'Gara F, Dobson ADW.

Mar Drugs. 2017 Jun 19;15(6). pii: E184. doi: 10.3390/md15060184.

14.

The aliphatic amidase AmiE is involved in regulation of Pseudomonas aeruginosa virulence.

Clamens T, Rosay T, Crépin A, Grandjean T, Kentache T, Hardouin J, Bortolotti P, Neidig A, Mooij M, Hillion M, Vieillard J, Cosette P, Overhage J, O'Gara F, Bouffartigues E, Dufour A, Chevalier S, Guery B, Cornelis P, Feuilloley MG, Lesouhaitier O.

Sci Rep. 2017 Jan 24;7:41178. doi: 10.1038/srep41178.

15.

Harnessing Bacterial Signals for Suppression of Biofilm Formation in the Nosocomial Fungal Pathogen Aspergillus fumigatus.

Reen FJ, Phelan JP, Woods DF, Shanahan R, Cano R, Clarke S, McGlacken GP, O'Gara F.

Front Microbiol. 2016 Dec 22;7:2074. doi: 10.3389/fmicb.2016.02074. eCollection 2016.

16.

The requirements at the C-3 position of alkylquinolones for signalling in Pseudomonas aeruginosa.

Shanahan R, Reen FJ, Cano R, O'Gara F, McGlacken GP.

Org Biomol Chem. 2017 Jan 4;15(2):306-310. doi: 10.1039/c6ob01930g.

PMID:
27901165
17.

Mining Microbial Signals for Enhanced Biodiscovery of Secondary Metabolites.

Reen FJ, Gutiérrez-Barranquero JA, O'Gara F.

Methods Mol Biol. 2017;1539:287-300.

PMID:
27900698
18.

CpxR Activates MexAB-OprM Efflux Pump Expression and Enhances Antibiotic Resistance in Both Laboratory and Clinical nalB-Type Isolates of Pseudomonas aeruginosa.

Tian ZX, Yi XX, Cho A, O'Gara F, Wang YP.

PLoS Pathog. 2016 Oct 13;12(10):e1005932. doi: 10.1371/journal.ppat.1005932. eCollection 2016 Oct.

19.

Synthesis and electrochemical detection of a thiazolyl-indole natural product isolated from the nosocomial pathogen Pseudomonas aeruginosa.

Buzid A, Muimhneacháin EÓ, Reen FJ, Hayes PE, Pardo LM, Shang F, O'Gara F, Sperry J, Luong JH, Glennon JD, McGlacken GP.

Anal Bioanal Chem. 2016 Sep;408(23):6361-7. doi: 10.1007/s00216-016-9749-8. Epub 2016 Jul 29.

PMID:
27473426
20.

Exploiting Interkingdom Interactions for Development of Small-Molecule Inhibitors of Candida albicans Biofilm Formation.

Reen FJ, Phelan JP, Gallagher L, Woods DF, Shanahan RM, Cano R, Ó Muimhneacháin E, McGlacken GP, O'Gara F.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5894-905. doi: 10.1128/AAC.00190-16. Print 2016 Oct.

21.

Diversity of Natural Product Biosynthetic Genes in the Microbiome of the Deep Sea Sponges Inflatella pellicula, Poecillastra compressa, and Stelletta normani.

Borchert E, Jackson SA, O'Gara F, Dobson AD.

Front Microbiol. 2016 Jun 29;7:1027. doi: 10.3389/fmicb.2016.01027. eCollection 2016.

22.

Bile signalling promotes chronic respiratory infections and antibiotic tolerance.

Reen FJ, Flynn S, Woods DF, Dunphy N, Chróinín MN, Mullane D, Stick S, Adams C, O'Gara F.

Sci Rep. 2016 Jul 19;6:29768. doi: 10.1038/srep29768.

23.

Molecular Signature of Pseudomonas aeruginosa with Simultaneous Nanomolar Detection of Quorum Sensing Signaling Molecules at a Boron-Doped Diamond Electrode.

Buzid A, Shang F, Reen FJ, Muimhneacháin EÓ, Clarke SL, Zhou L, Luong JH, O'Gara F, McGlacken GP, Glennon JD.

Sci Rep. 2016 Jul 18;6:30001. doi: 10.1038/srep30001.

24.

Bile acids destabilise HIF-1α and promote anti-tumour phenotypes in cancer cell models.

Phelan JP, Reen FJ, Dunphy N, O'Connor R, O'Gara F.

BMC Cancer. 2016 Jul 14;16:476. doi: 10.1186/s12885-016-2528-2.

25.

Is There Potential for Repurposing Statins as Novel Antimicrobials?

Hennessy E, Adams C, Reen FJ, O'Gara F.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5111-21. doi: 10.1128/AAC.00192-16. Print 2016 Sep. Review.

26.

Dissecting the regulation of bile-induced biofilm formation in Staphylococcus aureus.

Ulluwishewa D, Wang L, Pereira C, Flynn S, Cain E, Stick S, Reen FJ, Ramsay JP, O'Gara F.

Microbiology. 2016 Aug;162(8):1398-1406. doi: 10.1099/mic.0.000317. Epub 2016 Jun 2.

PMID:
27260167
27.

Comparative Genomic Analysis Reveals a Diverse Repertoire of Genes Involved in Prokaryote-Eukaryote Interactions within the Pseudovibrio Genus.

Romano S, Fernàndez-Guerra A, Reen FJ, Glöckner FO, Crowley SP, O'Sullivan O, Cotter PD, Adams C, Dobson AD, O'Gara F.

Front Microbiol. 2016 Mar 30;7:387. doi: 10.3389/fmicb.2016.00387. eCollection 2016.

28.

Integrated (Meta) Genomic and Synthetic Biology Approaches to Develop New Biocatalysts.

Parages ML, Gutiérrez-Barranquero JA, Reen FJ, Dobson AD, O'Gara F.

Mar Drugs. 2016 Mar 21;14(3). pii: E62. doi: 10.3390/md14030062. Review.

29.

Back to the Future of Soil Metagenomics.

Nesme J, Achouak W, Agathos SN, Bailey M, Baldrian P, Brunel D, Frostegård Å, Heulin T, Jansson JK, Jurkevitch E, Kruus KL, Kowalchuk GA, Lagares A, Lappin-Scott HM, Lemanceau P, Le Paslier D, Mandic-Mulec I, Murrell JC, Myrold DD, Nalin R, Nannipieri P, Neufeld JD, O'Gara F, Parnell JJ, Pühler A, Pylro V, Ramos JL, Roesch LF, Schloter M, Schleper C, Sczyrba A, Sessitsch A, Sjöling S, Sørensen J, Sørensen SJ, Tebbe CC, Topp E, Tsiamis G, van Elsas JD, van Keulen G, Widmer F, Wagner M, Zhang T, Zhang X, Zhao L, Zhu YG, Vogel TM, Simonet P.

Front Microbiol. 2016 Feb 10;7:73. doi: 10.3389/fmicb.2016.00073. eCollection 2016. No abstract available.

30.

Minimum Information about a Biosynthetic Gene cluster.

Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.

Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. No abstract available.

31.

The Sound of Silence: Activating Silent Biosynthetic Gene Clusters in Marine Microorganisms.

Reen FJ, Romano S, Dobson AD, O'Gara F.

Mar Drugs. 2015 Jul 31;13(8):4754-83. doi: 10.3390/md13084754. Review.

32.

The ocean sampling day consortium.

Kopf A, Bicak M, Kottmann R, Schnetzer J, Kostadinov I, Lehmann K, Fernandez-Guerra A, Jeanthon C, Rahav E, Ullrich M, Wichels A, Gerdts G, Polymenakou P, Kotoulas G, Siam R, Abdallah RZ, Sonnenschein EC, Cariou T, O'Gara F, Jackson S, Orlic S, Steinke M, Busch J, Duarte B, Caçador I, Canning-Clode J, Bobrova O, Marteinsson V, Reynisson E, Loureiro CM, Luna GM, Quero GM, Löscher CR, Kremp A, DeLorenzo ME, Øvreås L, Tolman J, LaRoche J, Penna A, Frischer M, Davis T, Katherine B, Meyer CP, Ramos S, Magalhães C, Jude-Lemeilleur F, Aguirre-Macedo ML, Wang S, Poulton N, Jones S, Collin R, Fuhrman JA, Conan P, Alonso C, Stambler N, Goodwin K, Yakimov MM, Baltar F, Bodrossy L, Van De Kamp J, Frampton DM, Ostrowski M, Van Ruth P, Malthouse P, Claus S, Deneudt K, Mortelmans J, Pitois S, Wallom D, Salter I, Costa R, Schroeder DC, Kandil MM, Amaral V, Biancalana F, Santana R, Pedrotti ML, Yoshida T, Ogata H, Ingleton T, Munnik K, Rodriguez-Ezpeleta N, Berteaux-Lecellier V, Wecker P, Cancio I, Vaulot D, Bienhold C, Ghazal H, Chaouni B, Essayeh S, Ettamimi S, Zaid el H, Boukhatem N, Bouali A, Chahboune R, Barrijal S, Timinouni M, El Otmani F, Bennani M, Mea M, Todorova N, Karamfilov V, Ten Hoopen P, Cochrane G, L'Haridon S, Bizsel KC, Vezzi A, Lauro FM, Martin P, Jensen RM, Hinks J, Gebbels S, Rosselli R, De Pascale F, Schiavon R, Dos Santos A, Villar E, Pesant S, Cataletto B, Malfatti F, Edirisinghe R, Silveira JA, Barbier M, Turk V, Tinta T, Fuller WJ, Salihoglu I, Serakinci N, Ergoren MC, Bresnan E, Iriberri J, Nyhus PA, Bente E, Karlsen HE, Golyshin PN, Gasol JM, Moncheva S, Dzhembekova N, Johnson Z, Sinigalliano CD, Gidley ML, Zingone A, Danovaro R, Tsiamis G, Clark MS, Costa AC, El Bour M, Martins AM, Collins RE, Ducluzeau AL, Martinez J, Costello MJ, Amaral-Zettler LA, Gilbert JA, Davies N, Field D, Glöckner FO.

Gigascience. 2015 Jun 19;4:27. doi: 10.1186/s13742-015-0066-5. eCollection 2015.

33.

Emerging concepts promising new horizons for marine biodiscovery and synthetic biology.

Reen FJ, Gutiérrez-Barranquero JA, Dobson AD, Adams C, O'Gara F.

Mar Drugs. 2015 May 13;13(5):2924-54. doi: 10.3390/md13052924. Review.

34.

A structure activity-relationship study of the bacterial signal molecule HHQ reveals swarming motility inhibition in Bacillus atrophaeus.

Reen FJ, Shanahan R, Cano R, O'Gara F, McGlacken GP.

Org Biomol Chem. 2015 May 21;13(19):5537-41. doi: 10.1039/c5ob00315f.

PMID:
25880413
35.

Maribacter spongiicola sp. nov. and Maribacter vaceletii sp. nov., isolated from marine sponges, and emended description of the genus Maribacter.

Jackson SA, Kennedy J, Morrissey JP, O'Gara F, Dobson AD.

Int J Syst Evol Microbiol. 2015 Jul;65(7):2097-103. doi: 10.1099/ijs.0.000224. Epub 2015 Apr 1.

PMID:
25833155
36.

Metagenomics for the discovery of novel biosurfactants of environmental interest from marine ecosystems.

Jackson SA, Borchert E, O'Gara F, Dobson AD.

Curr Opin Biotechnol. 2015 Jun;33:176-82. doi: 10.1016/j.copbio.2015.03.004. Epub 2015 Mar 24. Review.

PMID:
25812477
37.

Erratum to: deciphering the role of coumarin as a novel quorum sensing inhibitor suppressing virulence phenotypes in bacterial pathogens.

Gutiérrez-Barranquero JA, Reen FJ, McCarthy RR, Dobson AD, O'Gara F.

Appl Microbiol Biotechnol. 2015 Mar;99(6):2923. doi: 10.1007/s00253-015-6465-9. No abstract available.

PMID:
25693673
38.

Deciphering the role of coumarin as a novel quorum sensing inhibitor suppressing virulence phenotypes in bacterial pathogens.

Gutiérrez-Barranquero JA, Reen FJ, McCarthy RR, O'Gara F.

Appl Microbiol Biotechnol. 2015 Apr;99(7):3303-16. doi: 10.1007/s00253-015-6436-1. Epub 2015 Feb 12. Erratum in: Appl Microbiol Biotechnol. 2015 Mar;99(6):2923. Dobson, Alan D W [added].

PMID:
25672848
39.

A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans.

Barbosa TM, Phelan RW, Leong D, Morrissey JP, Adams C, Dobson AD, O'Gara F.

PLoS One. 2014 Dec 30;9(12):e115583. doi: 10.1371/journal.pone.0115583. eCollection 2014.

40.

Characterisation of non-autoinducing tropodithietic Acid (TDA) production from marine sponge Pseudovibrio species.

Harrington C, Reen FJ, Mooij MJ, Stewart FA, Chabot JB, Guerra AF, Glöckner FO, Nielsen KF, Gram L, Dobson AD, Adams C, O'Gara F.

Mar Drugs. 2014 Dec 10;12(12):5960-78. doi: 10.3390/md12125960.

41.

Marine Pseudovibrio sp. as a novel source of antimicrobials.

Crowley SP, O'Gara F, O'Sullivan O, Cotter PD, Dobson AD.

Mar Drugs. 2014 Dec 9;12(12):5916-29. doi: 10.3390/md12125916. Review.

42.

Tle distribution and diversity in metagenomic datasets reveal niche specialization.

Egan F, Reen FJ, O'Gara F.

Environ Microbiol Rep. 2015 Apr;7(2):194-203. doi: 10.1111/1758-2229.12222. Epub 2014 Dec 17.

PMID:
25345349
43.

One step preparation and electrochemical analysis of IQS, a cell-cell communication signal in the nosocomial pathogen Pseudomonas aeruginosa.

Shang F, Muimhneacháin EÓ, Jerry Reen F, Buzid A, O'Gara F, Luong JHT, Glennon JD, McGlacken GP.

Bioorg Med Chem Lett. 2014 Oct 1;24(19):4703-4707. doi: 10.1016/j.bmcl.2014.08.023. Epub 2014 Aug 14.

PMID:
25190465
44.

The impact of simvastatin on pulmonary effectors of Pseudomonas aeruginosa infection.

Hennessy E, O'Callaghan J, Mooij MJ, Legendre C, Camacho-Vanegas O, Camacho SC, Adams C, Martignetti JA, O'Gara F.

PLoS One. 2014 Jul 10;9(7):e102200. doi: 10.1371/journal.pone.0102200. eCollection 2014.

45.

Emerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds.

Rocha-Martin J, Harrington C, Dobson AD, O'Gara F.

Mar Drugs. 2014 Jun 10;12(6):3516-59. doi: 10.3390/md12063516. Review.

46.

Bile acids repress hypoxia-inducible factor 1 signaling and modulate the airway immune response.

Legendre C, Reen FJ, Woods DF, Mooij MJ, Adams C, O'Gara F.

Infect Immun. 2014 Sep;82(9):3531-41. doi: 10.1128/IAI.00674-13. Epub 2014 Jun 9.

47.

Metabolomic profiling and genomic study of a marine sponge-associated Streptomyces sp.

Viegelmann C, Margassery LM, Kennedy J, Zhang T, O'Brien C, O'Gara F, Morrissey JP, Dobson AD, Edrada-Ebel R.

Mar Drugs. 2014 Jun 2;12(6):3323-51. doi: 10.3390/md12063323.

48.

A new regulator of pathogenicity (bvlR) is required for full virulence and tight microcolony formation in Pseudomonas aeruginosa.

McCarthy RR, Mooij MJ, Reen FJ, Lesouhaitier O, O'Gara F.

Microbiology. 2014 Jul;160(Pt 7):1488-500. doi: 10.1099/mic.0.075291-0. Epub 2014 May 14.

PMID:
24829363
49.

Aspirated bile: a major host trigger modulating respiratory pathogen colonisation in cystic fibrosis patients.

Reen FJ, Woods DF, Mooij MJ, Chróinín MN, Mullane D, Zhou L, Quille J, Fitzpatrick D, Glennon JD, McGlacken GP, Adams C, O'Gara F.

Eur J Clin Microbiol Infect Dis. 2014 Oct;33(10):1763-71. doi: 10.1007/s10096-014-2133-8. Epub 2014 May 11.

50.

Inhibition of co-colonizing cystic fibrosis-associated pathogens by Pseudomonas aeruginosa and Burkholderia multivorans.

Costello A, Reen FJ, O'Gara F, Callaghan M, McClean S.

Microbiology. 2014 Jul;160(Pt 7):1474-87. doi: 10.1099/mic.0.074203-0. Epub 2014 Apr 30.

PMID:
24790091

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