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Items: 20

1.

Sequence-Directed Action of RSC Remodeler and General Regulatory Factors Modulates +1 Nucleosome Position to Facilitate Transcription.

Kubik S, O'Duibhir E, de Jonge WJ, Mattarocci S, Albert B, Falcone JL, Bruzzone MJ, Holstege FCP, Shore D.

Mol Cell. 2018 Jul 5;71(1):89-102.e5. doi: 10.1016/j.molcel.2018.05.030.

PMID:
29979971
2.

Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells.

Lyall MJ, Cartier J, Thomson JP, Cameron K, Meseguer-Ripolles J, O'Duibhir E, Szkolnicka D, Villarin BL, Wang Y, Blanco GR, Dunn WB, Meehan RR, Hay DC, Drake AJ.

Philos Trans R Soc Lond B Biol Sci. 2018 Jul 5;373(1750). pii: 20170362. doi: 10.1098/rstb.2017.0362.

3.

An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein.

Dewari PS, Southgate B, Mccarten K, Monogarov G, O'Duibhir E, Quinn N, Tyrer A, Leitner MC, Plumb C, Kalantzaki M, Blin C, Finch R, Bressan RB, Morrison G, Jacobi AM, Behlke MA, von Kriegsheim A, Tomlinson S, Krijgsveld J, Pollard SM.

Elife. 2018 Apr 11;7. pii: e35069. doi: 10.7554/eLife.35069.

4.

Corrigendum: Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.

Raven A, Lu WY, Man TY, Ferreira-Gonzalez S, O'Duibhir E, Dwyer BJ, Thomson JP, Meehan RR, Bogorad R, Koteliansky V, Kotelevtsev Y, Ffrench-Constant C, Boulter L, Forbes SJ.

Nature. 2018 Mar 14;555(7696):402. doi: 10.1038/nature25996.

PMID:
29542689
5.

Paracrine cellular senescence exacerbates biliary injury and impairs regeneration.

Ferreira-Gonzalez S, Lu WY, Raven A, Dwyer B, Man TY, O'Duibhir E, Lewis PJS, Campana L, Kendall TJ, Bird TG, Tarrats N, Acosta JC, Boulter L, Forbes SJ.

Nat Commun. 2018 Mar 9;9(1):1020. doi: 10.1038/s41467-018-03299-5.

6.

Machine Learning Enables Live Label-Free Phenotypic Screening in Three Dimensions.

O'Duibhir E, Paris J, Lawson H, Sepulveda C, Shenton DD, Carragher NO, Kranc KR.

Assay Drug Dev Technol. 2018 Jan;16(1):51-63. doi: 10.1089/adt.2017.819.

PMID:
29345979
7.

Erratum: Author Correction: Injection of embryonic stem cell-derived macrophages ameliorates fibrosis in a murine model of liver injury.

Haideri SS, McKinnon AC, Taylor AH, Kirkwood P, Lewis PJS, O'Duibhir E, Vernay B, Forbes S, Forrester LM.

NPJ Regen Med. 2017 Nov 13;2:31. doi: 10.1038/s41536-017-0035-y. eCollection 2017.

8.

Injection of embryonic stem cell derived macrophages ameliorates fibrosis in a murine model of liver injury.

Haideri SS, McKinnon AC, Taylor AH, Kirkwood P, Starkey Lewis PJ, O'Duibhir E, Vernay B, Forbes S, Forrester LM.

NPJ Regen Med. 2017 May 23;2:14. doi: 10.1038/s41536-017-0017-0. eCollection 2017. Erratum in: NPJ Regen Med. 2017 Nov 13;2:31.

9.

The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury.

Campana L, Starkey Lewis PJ, Pellicoro A, Aucott RL, Man J, O'Duibhir E, Mok SE, Ferreira-Gonzalez S, Livingstone E, Greenhalgh SN, Hull KL, Kendall TJ, Vernimmen D, Henderson NC, Boulter L, Gregory CD, Feng Y, Anderton SM, Forbes SJ, Iredale JP.

J Immunol. 2018 Feb 1;200(3):1169-1187. doi: 10.4049/jimmunol.1701247. Epub 2017 Dec 20.

10.

An Image-Based miRNA Screen Identifies miRNA-135s As Regulators of CNS Axon Growth and Regeneration by Targeting Krüppel-like Factor 4.

van Battum EY, Verhagen MG, Vangoor VR, Fujita Y, Derijck AAHA, O'Duibhir E, Giuliani G, de Gunst T, Adolfs Y, Lelieveld D, Egan D, Schaapveld RQJ, Yamashita T, Pasterkamp RJ.

J Neurosci. 2018 Jan 17;38(3):613-630. doi: 10.1523/JNEUROSCI.0662-17.2017. Epub 2017 Dec 1.

11.

Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.

Raven A, Lu WY, Man TY, Ferreira-Gonzalez S, O'Duibhir E, Dwyer BJ, Thomson JP, Meehan RR, Bogorad R, Koteliansky V, Kotelevtsev Y, Ffrench-Constant C, Boulter L, Forbes SJ.

Nature. 2017 Jul 20;547(7663):350-354. doi: 10.1038/nature23015. Epub 2017 Jul 12. Erratum in: Nature. 2018 Mar 14;555(7696):402.

12.

Molecular mechanisms that distinguish TFIID housekeeping from regulatable SAGA promoters.

de Jonge WJ, O'Duibhir E, Lijnzaad P, van Leenen D, Groot Koerkamp MJ, Kemmeren P, Holstege FC.

EMBO J. 2017 Feb 1;36(3):274-290. doi: 10.15252/embj.201695621. Epub 2016 Dec 15.

13.

Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screening.

O'Duibhir E, Carragher NO, Pollard SM.

Mol Cell Neurosci. 2017 Apr;80:198-207. doi: 10.1016/j.mcn.2016.11.001. Epub 2016 Nov 4. Review.

14.

Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells.

Oosthuyzen W, Scullion KM, Ivy JR, Morrison EE, Hunter RW, Starkey Lewis PJ, O'Duibhir E, Street JM, Caporali A, Gregory CD, Forbes SJ, Webb DJ, Bailey MA, Dear JW.

J Am Soc Nephrol. 2016 Nov;27(11):3345-3355. Epub 2016 Mar 28.

15.

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.

Vukovic M, Guitart AV, Sepulveda C, Villacreces A, O'Duibhir E, Panagopoulou TI, Ivens A, Menendez-Gonzalez J, Iglesias JM, Allen L, Glykofrydis F, Subramani C, Armesilla-Diaz A, Post AE, Schaak K, Gezer D, So CW, Holyoake TL, Wood A, O'Carroll D, Ratcliffe PJ, Kranc KR.

J Exp Med. 2015 Dec 14;212(13):2223-34. doi: 10.1084/jem.20150452. Epub 2015 Dec 7.

16.

Cell cycle population effects in perturbation studies.

O'Duibhir E, Lijnzaad P, Benschop JJ, Lenstra TL, van Leenen D, Groot Koerkamp MJ, Margaritis T, Brok MO, Kemmeren P, Holstege FC.

Mol Syst Biol. 2014 Jun 21;10:732. doi: 10.15252/msb.20145172.

17.

Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.

Kemmeren P, Sameith K, van de Pasch LA, Benschop JJ, Lenstra TL, Margaritis T, O'Duibhir E, Apweiler E, van Wageningen S, Ko CW, van Heesch S, Kashani MM, Ampatziadis-Michailidis G, Brok MO, Brabers NA, Miles AJ, Bouwmeester D, van Hooff SR, van Bakel H, Sluiters E, Bakker LV, Snel B, Lijnzaad P, van Leenen D, Groot Koerkamp MJ, Holstege FC.

Cell. 2014 Apr 24;157(3):740-52. doi: 10.1016/j.cell.2014.02.054.

18.

Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II.

Meinel DM, Burkert-Kautzsch C, Kieser A, O'Duibhir E, Siebert M, Mayer A, Cramer P, Söding J, Holstege FC, Sträßer K.

PLoS Genet. 2013 Nov;9(11):e1003914. doi: 10.1371/journal.pgen.1003914. Epub 2013 Nov 14.

19.

Pmch-deficiency in rats is associated with normal adipocyte differentiation and lower sympathetic adipose drive.

Mul JD, O'Duibhir E, Shrestha YB, Koppen A, Vargoviç P, Toonen PW, Zarebidaki E, Kvetnansky R, Kalkhoven E, Cuppen E, Bartness TJ.

PLoS One. 2013;8(3):e60214. doi: 10.1371/journal.pone.0060214. Epub 2013 Mar 26.

20.

Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response.

Kan AA, van Erp S, Derijck AA, de Wit M, Hessel EV, O'Duibhir E, de Jager W, Van Rijen PC, Gosselaar PH, de Graan PN, Pasterkamp RJ.

Cell Mol Life Sci. 2012 Sep;69(18):3127-45. doi: 10.1007/s00018-012-0992-7. Epub 2012 Apr 26.

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