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Items: 1 to 50 of 890

1.

Feedback regulation of locomotion by motoneurons in the vertebrate spinal cord.

Falgairolle M, O'Donovan MJ.

Curr Opin Physiol. 2019 Apr;8:50-55. doi: 10.1016/j.cophys.2018.12.009. Epub 2019 Jan 2.

PMID:
31799489
2.

No Effect of Genome-Wide Significant Schizophrenia Risk Variation at the DRD2 Locus on the Allelic Expression of DRD2 in Postmortem Striatum.

Toste CC, Duarte RRR, Jeffries AR, Selvackadunco S, Troakes C, O'Donovan MC, Hill MJ, Bray NJ.

Mol Neuropsychiatry. 2019 Oct;5(4):212-217. doi: 10.1159/000501022. Epub 2019 Jul 15.

3.

Characterization of Single Gene Copy Number Variants in Schizophrenia.

Szatkiewicz JP, Fromer M, Nonneman RJ, Ancalade N, Johnson JS, Stahl EA, Rees E, Bergen SE, Hultman CM, Kirov G, O'Donovan M, Owen M, Holmans P, Sklar P, Sullivan PF, Purcell SM, Crowley JJ, Ruderfer DM.

Biol Psychiatry. 2019 Oct 4. pii: S0006-3223(19)31748-2. doi: 10.1016/j.biopsych.2019.09.023. [Epub ahead of print]

PMID:
31767120
4.

Comparison of Genetic Liability for Sleep Traits Among Individuals With Bipolar Disorder I or II and Control Participants.

Lewis KJS, Richards A, Karlsson R, Leonenko G, Jones SE, Jones HJ, Gordon-Smith K, Forty L, Escott-Price V, Owen MJ, Weedon MN, Jones L, Craddock N, Jones I, Landén M, O'Donovan MC, Di Florio A.

JAMA Psychiatry. 2019 Nov 21. doi: 10.1001/jamapsychiatry.2019.4079. [Epub ahead of print]

PMID:
31751445
5.

Comparative genetic architectures of schizophrenia in East Asian and European populations.

Lam M, Chen CY, Li Z, Martin AR, Bryois J, Ma X, Gaspar H, Ikeda M, Benyamin B, Brown BC, Liu R, Zhou W, Guan L, Kamatani Y, Kim SW, Kubo M, Kusumawardhani AAAA, Liu CM, Ma H, Periyasamy S, Takahashi A, Xu Z, Yu H, Zhu F; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Indonesia Schizophrenia Consortium; Genetic REsearch on schizophreniA neTwork-China and the Netherlands (GREAT-CN), Chen WJ, Faraone S, Glatt SJ, He L, Hyman SE, Hwu HG, McCarroll SA, Neale BM, Sklar P, Wildenauer DB, Yu X, Zhang D, Mowry BJ, Lee J, Holmans P, Xu S, Sullivan PF, Ripke S, O'Donovan MC, Daly MJ, Qin S, Sham P, Iwata N, Hong KS, Schwab SG, Yue W, Tsuang M, Liu J, Ma X, Kahn RS, Shi Y, Huang H.

Nat Genet. 2019 Dec;51(12):1670-1678. doi: 10.1038/s41588-019-0512-x. Epub 2019 Nov 18.

PMID:
31740837
6.

Outcomes and outcomes measurements used in intervention studies of pelvic girdle pain and lumbopelvic pain: a systematic review.

Wuytack F, O'Donovan M.

Chiropr Man Therap. 2019 Nov 5;27:62. doi: 10.1186/s12998-019-0279-2. eCollection 2019. Review.

7.

A Transcriptome-Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia.

Hall LS, Medway CW, Pain O, Pardinas AF, Rees EG, Escott-Price V, Pocklington A, Bray NJ, Holmans PA, Walters JTR, Owen MJ, O'Donovan MC.

Hum Mol Genet. 2019 Nov 6. pii: ddz253. doi: 10.1093/hmg/ddz253. [Epub ahead of print]

PMID:
31691811
8.

Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits.

Legge SE, Jones HJ, Kendall KM, Pardiñas AF, Menzies G, Bracher-Smith M, Escott-Price V, Rees E, Davis KAS, Hotopf M, Savage JE, Posthuma D, Holmans P, Kirov G, Owen MJ, O'Donovan MC, Zammit S, Walters JTR.

JAMA Psychiatry. 2019 Sep 25. doi: 10.1001/jamapsychiatry.2019.2508. [Epub ahead of print]

9.

Effect of deinstitutionalisation for adults with intellectual disabilities on costs: a systematic review.

May P, Lombard Vance R, Murphy E, O'Donovan MA, Webb N, Sheaf G, McCallion P, Stancliffe R, Normand C, Smith V, McCarron M.

BMJ Open. 2019 Sep 20;9(9):e025736. doi: 10.1136/bmjopen-2018-025736.

10.

Letter to the editor: Is polygenic risk for Parkinson's disease associated with less risk of first episode psychosis?

Quattrone D, Richards A, Reininghaus U, Vassos E, O'Donovan M, Lewis C, Di Forti M.

Psychol Med. 2019 Sep 19:1-4. doi: 10.1017/S0033291719002435. [Epub ahead of print] No abstract available.

PMID:
31533866
11.

V1 interneurons regulate the pattern and frequency of locomotor-like activity in the neonatal mouse spinal cord.

Falgairolle M, O'Donovan MJ.

PLoS Biol. 2019 Sep 12;17(9):e3000447. doi: 10.1371/journal.pbio.3000447. eCollection 2019 Sep.

12.

Estimating Exposome Score for Schizophrenia Using Predictive Modeling Approach in Two Independent Samples: The Results From the EUGEI Study.

Pries LK, Lage-Castellanos A, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altinyazar V, Yalinçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators , Arango C, O'Donovan M, Rutten BPF, van Os J, Guloksuz S.

Schizophr Bull. 2019 Sep 11;45(5):960-965. doi: 10.1093/schbul/sbz054.

PMID:
31508804
13.

Pre-frailty as a multi-dimensional construct: A systematic review of definitions in the scientific literature.

Sezgin D, Liew A, O'Donovan MR, O'Caoimh R.

Geriatr Nurs. 2019 Aug 26. pii: S0197-4572(19)30347-7. doi: 10.1016/j.gerinurse.2019.08.004. [Epub ahead of print]

PMID:
31466806
14.

The "Grass-Fed" Milk Story: Understanding the Impact of Pasture Feeding on the Composition and Quality of Bovine Milk.

Alothman M, Hogan SA, Hennessy D, Dillon P, Kilcawley KN, O'Donovan M, Tobin J, Fenelon MA, O'Callaghan TF.

Foods. 2019 Aug 17;8(8). pii: E350. doi: 10.3390/foods8080350. Review.

15.

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y; Alzheimer Disease Genetics Consortium (ADGC); European Alzheimer’s Disease Initiative (EADI); Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE); Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, O'Donovan MC, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA.

Nat Genet. 2019 Sep;51(9):1423-1424. doi: 10.1038/s41588-019-0495-7.

PMID:
31417202
16.

Replicated evidence that endophenotypic expression of schizophrenia polygenic risk is greater in healthy siblings of patients compared to controls, suggesting gene-environment interaction. The EUGEI study.

van Os J, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome Investigators (GROUP), Arango C, O'Donovan M, Rutten BPF, Guloksuz S.

Psychol Med. 2019 Aug 15:1-14. doi: 10.1017/S003329171900196X. [Epub ahead of print]

PMID:
31414981
17.

Dairy cow feeding system alters the characteristics of low-heat skim milk powder and processability of reconstituted skim milk.

Gulati A, Hennessy D, O'Donovan M, McManus JJ, Fenelon MA, Guinee TP.

J Dairy Sci. 2019 Oct;102(10):8630-8647. doi: 10.3168/jds.2018-15884. Epub 2019 Aug 1.

PMID:
31378501
18.

Correction: The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.

Ward J, Tunbridge EM, Sandor C, Lyall LM, Ferguson A, Strawbridge RJ, Lyall DM, Cullen B, Graham N, Johnston KJA, Webber C, Escott-Price V, O'Donovan M, Pell JP, Bailey MES, Harrison PJ, Smith DJ.

Mol Psychiatry. 2019 Jul 30. doi: 10.1038/s41380-019-0466-5. [Epub ahead of print]

PMID:
31363164
19.

Integrated Care Models for Managing and Preventing Frailty: A Systematic Review for the European Joint Action on Frailty Prevention (ADVANTAGE JA).

Hendry A, Vanhecke E, Carriazo AM, López-Samaniego L, Espinosa JM, Sezgin D, O'Donovan M, Hammar T, Ferry P, Vella A, Bacaicoa OA, Braga M, Ciutan M, Velivasi A, Lamprini Koula M, Van der Heyden J, Liew A, O'Caoimh R.

Transl Med UniSa. 2019 Jan 6;19:5-10. eCollection 2019 Jan-Jun.

20.

Non-pharmacological treatments for sleep disturbance in mild cognitive impairment and dementia: A systematic review and meta-analysis.

O'Caoimh R, Mannion H, Sezgin D, O'Donovan MR, Liew A, Molloy DW.

Maturitas. 2019 Sep;127:82-94. doi: 10.1016/j.maturitas.2019.06.007. Epub 2019 Jun 21.

PMID:
31351523
21.

The Relationship Between Common Variant Schizophrenia Liability and Number of Offspring in the UK Biobank: Response to Lawn et al.

Escott-Price V, Pardiñas AF, Santiago E, Walters J, Kirov G, Owen MJ, O'Donovan MC.

Am J Psychiatry. 2019 Jul 1;176(7):574-575. doi: 10.1176/appi.ajp.2019.19010071r. No abstract available.

PMID:
31256626
22.

Identifying Novel Types of Irritability Using a Developmental Genetic Approach.

Riglin L, Eyre O, Thapar AK, Stringaris A, Leibenluft E, Pine DS, Tilling K, Davey Smith G, O'Donovan MC, Thapar A.

Am J Psychiatry. 2019 Aug 1;176(8):635-642. doi: 10.1176/appi.ajp.2019.18101134. Epub 2019 Jul 1.

PMID:
31256611
23.

Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics.

Pain O, Pocklington AJ, Holmans PA, Bray NJ, O'Brien HE, Hall LS, Pardiñas AF, O'Donovan MC, Owen MJ, Anney R.

Biol Psychiatry. 2019 Aug 15;86(4):265-273. doi: 10.1016/j.biopsych.2019.04.034. Epub 2019 May 11.

24.

The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia.

Richards AL, Pardiñas AF, Frizzati A, Tansey KE, Lynham AJ, Holmans P, Legge SE, Savage JE, Agartz I, Andreassen OA, Blokland GAM, Corvin A, Cosgrove D, Degenhardt F, Djurovic S, Espeseth T, Ferraro L, Gayer-Anderson C, Giegling I, van Haren NE, Hartmann AM, Hubert JJ, Jönsson EG, Konte B, Lennertz L, Olde Loohuis LM, Melle I, Morgan C, Morris DW, Murray RM, Nyman H, Ophoff RA; GROUP Investigators, van Os J; EUGEI WP2 Group; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Petryshen TL, Quattrone D, Rietschel M, Rujescu D, Rutten BPF, Streit F, Strohmaier J, Sullivan PF, Sundet K, Wagner M, Escott-Price V, Owen MJ, Donohoe G, O'Donovan MC, Walters JTR.

Schizophr Bull. 2019 Jun 17. pii: sbz061. doi: 10.1093/schbul/sbz061. [Epub ahead of print]

PMID:
31206164
25.

The genetics of neuropsychiatric disorders.

Bray NJ, O'Donovan MC.

Brain Neurosci Adv. 2019 May 30;2. doi: 10.1177/2398212818799271. Epub 2018 Oct 12.

26.

The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.

Ward J, Tunbridge EM, Sandor C, Lyall LM, Ferguson A, Strawbridge RJ, Lyall DM, Cullen B, Graham N, Johnston KJA, Webber C, Escott-Price V, O'Donovan M, Pell JP, Bailey MES, Harrison PJ, Smith DJ.

Mol Psychiatry. 2019 Jun 5. doi: 10.1038/s41380-019-0439-8. [Epub ahead of print] Erratum in: Mol Psychiatry. 2019 Jul 30;:.

PMID:
31168069
27.

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

Mullins N, Bigdeli TB, Børglum AD, Coleman JRI, Demontis D, Mehta D, Power RA, Ripke S, Stahl EA, Starnawska A, Anjorin A; M.R.C.Psych, Corvin A, Sanders AR, Forstner AJ, Reif A, Koller AC, Świątkowska B, Baune BT, Müller-Myhsok B, Penninx BWJH, Pato C, Zai C, Rujescu D, Hougaard DM, Quested D, Levinson DF, Binder EB, Byrne EM, Agerbo E; Dr.Med.Sc, Streit F, Mayoral F, Bellivier F, Degenhardt F, Breen G, Morken G, Turecki G, Rouleau GA, Grabe HJ, Völzke H, Jones I, Giegling I, Agartz I, Melle I, Lawrence J; M.R.C.Psych, Walters JTR, Strohmaier J, Shi J, Hauser J, Biernacka JM, Vincent JB, Kelsoe J, Strauss JS, Lissowska J, Pimm J; M.R.C.Psych, Smoller JW, Guzman-Parra J, Berger K, Scott LJ, Jones LA, Azevedo MH, Trzaskowski M, Kogevinas M, Rietschel M, Boks M, Ising M, Grigoroiu-Serbanescu M, Hamshere ML, Leboyer M, Frye M, Nöthen MM, Alda M, Preisig M, Nordentoft M, Boehnke M, O'Donovan MC, Owen MJ, Pato MT, Renteria ME, Budde M; Dipl.-Psych, Weissman MM, Wray NR, Bass N; M.R.C.Psych, Craddock N, Smeland OB, Andreassen OA, Mors O, Gejman PV, Sklar P, McGrath P, Hoffmann P, McGuffin P, Lee PH, Mortensen PB, Kahn RS, Ophoff RA, Adolfsson R, Van der Auwera S, Djurovic S, Kloiber S, Heilmann-Heimbach S, Jamain S, Hamilton SP, McElroy SL, Lucae S, Cichon S, Schulze TG, Hansen T, Werge T, Air TM, Nimgaonkar V, Appadurai V, Cahn W, Milaneschi Y; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Fanous AH, Kendler KS, McQuillin A, Lewis CM.

Am J Psychiatry. 2019 Aug 1;176(8):651-660. doi: 10.1176/appi.ajp.2019.18080957. Epub 2019 Jun 5.

PMID:
31164008
28.

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AM, Plomin R, Porteous DJ, Wray NR, Caballero A, Geschwind DH, Huckins LM, Ruderfer DM, Santiago E, Sklar P, Stahl EA, Won H, Agerbo E, Als TD, Andreassen OA, Bækvad-Hansen M, Mortensen PB, Pedersen CB, Børglum AD, Bybjerg-Grauholm J, Djurovic S, Durmishi N, Pedersen MG, Golimbet V, Grove J, Hougaard DM, Mattheisen M, Molden E, Mors O, Nordentoft M, Pejovic-Milovancevic M, Sigurdsson E, Silagadze T, Hansen CS, Stefansson K, Stefansson H, Steinberg S, Tosato S, Werge T; GERAD1 Consortium; CRESTAR Consortium, Collier DA, Rujescu D, Kirov G, Owen MJ, O'Donovan MC, Walters JTR.

Nat Genet. 2019 Jul;51(7):1193. doi: 10.1038/s41588-019-0450-7.

29.

Clinical indicators of treatment-resistant psychosis.

Legge SE, Dennison CA, Pardiñas AF, Rees E, Lynham AJ, Hopkins L, Bates L, Kirov G, Owen MJ, O'Donovan MC, Walters JTR.

Br J Psychiatry. 2019 Jun 3:1-8. doi: 10.1192/bjp.2019.120. [Epub ahead of print]

PMID:
31155017
30.

Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.

Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K, Boocock J, Roussos P, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, Børglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.

Nat Genet. 2019 Jun;51(6):1068. doi: 10.1038/s41588-019-0435-6.

31.

Examining the independent and joint effects of molecular genetic liability and environmental exposures in schizophrenia: results from the EUGEI study.

Guloksuz S, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran E, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşog Lu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators, Arango C, O'Donovan M, Rutten BPF, van Os J.

World Psychiatry. 2019 Jun;18(2):173-182. doi: 10.1002/wps.20629.

32.

Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction.

Bornschein J, Wernisch L, Secrier M, Miremadi A, Perner J, MacRae S, O'Donovan M, Newton R, Menon S, Bower L, Eldridge MD, Devonshire G, Cheah C, Turkington R, Hardwick RH, Selgrad M, Venerito M, Malfertheiner P; OCCAMS Consortium, Fitzgerald RC.

Int J Cancer. 2019 Dec 15;145(12):3389-3401. doi: 10.1002/ijc.32384. Epub 2019 May 17.

33.

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, Bækvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, Bøen E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvsåshagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Frisén L, Gade K, Gage D, Garnham J, Giambartolomei C, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS, Juréus A, Kandaswamy R, Karlsson R, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koller AC, Kupka R, Lavebratt C, Lawrence J, Lawson WB, Leber M, Lee PH, Levy SE, Li JZ, Liu C, Lucae S, Maaser A, MacIntyre DJ, Mahon PB, Maier W, Martinsson L, McCarroll S, McGuffin P, McInnis MG, McKay JD, Medeiros H, Medland SE, Meng F, Milani L, Montgomery GW, Morris DW, Mühleisen TW, Mullins N, Nguyen H, Nievergelt CM, Adolfsson AN, Nwulia EA, O'Donovan C, Loohuis LMO, Ori APS, Oruc L, Ösby U, Perlis RH, Perry A, Pfennig A, Potash JB, Purcell SM, Regeer EJ, Reif A, Reinbold CS, Rice JP, Rivas F, Rivera M, Roussos P, Ruderfer DM, Ryu E, Sánchez-Mora C, Schatzberg AF, Scheftner WA, Schork NJ, Shannon Weickert C, Shehktman T, Shilling PD, Sigurdsson E, Slaney C, Smeland OB, Sobell JL, Søholm Hansen C, Spijker AT, St Clair D, Steffens M, Strauss JS, Streit F, Strohmaier J, Szelinger S, Thompson RC, Thorgeirsson TE, Treutlein J, Vedder H, Wang W, Watson SJ, Weickert TW, Witt SH, Xi S, Xu W, Young AH, Zandi P, Zhang P, Zöllner S; eQTLGen Consortium; BIOS Consortium, Adolfsson R, Agartz I, Alda M, Backlund L, Baune BT, Bellivier F, Berrettini WH, Biernacka JM, Blackwood DHR, Boehnke M, Børglum AD, Corvin A, Craddock N, Daly MJ, Dannlowski U, Esko T, Etain B, Frye M, Fullerton JM, Gershon ES, Gill M, Goes F, Grigoroiu-Serbanescu M, Hauser J, Hougaard DM, Hultman CM, Jones I, Jones LA, Kahn RS, Kirov G, Landén M, Leboyer M, Lewis CM, Li QS, Lissowska J, Martin NG, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Metspalu A, Mitchell PB, Morken G, Mors O, Mortensen PB, Müller-Myhsok B, Myers RM, Neale BM, Nimgaonkar V, Nordentoft M, Nöthen MM, O'Donovan MC, Oedegaard KJ, Owen MJ, Paciga SA, Pato C, Pato MT, Posthuma D, Ramos-Quiroga JA, Ribasés M, Rietschel M, Rouleau GA, Schalling M, Schofield PR, Schulze TG, Serretti A, Smoller JW, Stefansson H, Stefansson K, Stordal E, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Werge T, Nurnberger JI, Wray NR, Di Florio A, Edenberg HJ, Cichon S, Ophoff RA, Scott LJ, Andreassen OA, Kelsoe J, Sklar P; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium.

Nat Genet. 2019 May;51(5):793-803. doi: 10.1038/s41588-019-0397-8. Epub 2019 May 1.

PMID:
31043756
34.

Effect of deinstitutionalisation on quality of life for adults with intellectual disabilities: a systematic review.

McCarron M, Lombard-Vance R, Murphy E, May P, Webb N, Sheaf G, McCallion P, Stancliffe R, Normand C, Smith V, O'Donovan MA.

BMJ Open. 2019 Apr 25;9(4):e025735. doi: 10.1136/bmjopen-2018-025735.

35.

Association of Rare Copy Number Variants With Risk of Depression.

Kendall KM, Rees E, Bracher-Smith M, Legge S, Riglin L, Zammit S, O'Donovan MC, Owen MJ, Jones I, Kirov G, Walters JTR.

JAMA Psychiatry. 2019 Apr 17. doi: 10.1001/jamapsychiatry.2019.0566. [Epub ahead of print]

36.

Development and Validation of Confocal Endomicroscopy Diagnostic Criteria for Low-Grade Dysplasia in Barrett's Esophagus.

di Pietro M, Bertani H, OʼDonovan M, Santos P, Alastal H, Phillips R, Ortiz-Fernández-Sordo J, Iacucci M, Modolell I, Reggiani Bonetti L, Ragunath K, Wernisch L.

Clin Transl Gastroenterol. 2019 Apr;10(4):e00014. doi: 10.14309/ctg.0000000000000014.

37.

Pharmacogenomic Variants and Drug Interactions Identified Through the Genetic Analysis of Clozapine Metabolism.

Pardiñas AF, Nalmpanti M, Pocklington AJ, Legge SE, Medway C, King A, Jansen J, Helthuis M, Zammit S, MacCabe J, Owen MJ, O'Donovan MC, Walters JTR.

Am J Psychiatry. 2019 Jun 1;176(6):477-486. doi: 10.1176/appi.ajp.2019.18050589. Epub 2019 Mar 29.

PMID:
30922102
38.

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.

Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K, Boocock J, Roussos P, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, Børglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.

Nat Genet. 2019 Apr;51(4):659-674. doi: 10.1038/s41588-019-0364-4. Epub 2019 Mar 25. Erratum in: Nat Genet. 2019 Jun;51(6):1068.

PMID:
30911161
39.
40.

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.

Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O'Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Donohoe G, Gill M, Corvin A, Morris DW.

Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002/ajmg.b.32716. Epub 2019 Feb 23.

PMID:
30801977
41.

Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank.

Kendall KM, Bracher-Smith M, Fitzpatrick H, Lynham A, Rees E, Escott-Price V, Owen MJ, O'Donovan MC, Walters JTR, Kirov G.

Br J Psychiatry. 2019 May;214(5):297-304. doi: 10.1192/bjp.2018.301. Epub 2019 Feb 15.

42.

The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic.

Frankell AM, Jammula S, Li X, Contino G, Killcoyne S, Abbas S, Perner J, Bower L, Devonshire G, Ococks E, Grehan N, Mok J, O'Donovan M, MacRae S, Eldridge MD, Tavaré S; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, Fitzgerald RC.

Nat Genet. 2019 Mar;51(3):506-516. doi: 10.1038/s41588-018-0331-5. Epub 2019 Feb 4.

43.

Dynamic expression of genes associated with schizophrenia and bipolar disorder across development.

Clifton NE, Hannon E, Harwood JC, Di Florio A, Thomas KL, Holmans PA, Walters JTR, O'Donovan MC, Owen MJ, Pocklington AJ, Hall J.

Transl Psychiatry. 2019 Feb 4;9(1):74. doi: 10.1038/s41398-019-0405-x.

44.

Defining frailty for healthcare practice and research: A qualitative systematic review with thematic analysis.

Sezgin D, O'Donovan M, Cornally N, Liew A, O'Caoimh R.

Int J Nurs Stud. 2019 Apr;92:16-26. doi: 10.1016/j.ijnurstu.2018.12.014. Epub 2018 Dec 31.

PMID:
30690163
45.

A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia.

Legge SE, Pardiñas AF, Helthuis M, Jansen JA, Jollie K, Knapper S, MacCabe JH, Rujescu D, Collier DA, O'Donovan MC, Owen MJ, Walters JTR.

Mol Psychiatry. 2019 Mar;24(3):328-337. doi: 10.1038/s41380-018-0335-7. Epub 2019 Jan 15.

PMID:
30647433
46.

Genetic liability to schizophrenia is negatively associated with educational attainment in UK Biobank.

Escott-Price V, Bracher-Smith M, Menzies G, Walters J, Kirov G, Owen MJ, O'Donovan MC.

Mol Psychiatry. 2019 Jan 4. doi: 10.1038/s41380-018-0328-6. [Epub ahead of print] No abstract available.

PMID:
30610204
47.

The Relationship Between Common Variant Schizophrenia Liability and Number of Offspring in the UK Biobank.

Escott-Price V, Pardiñas AF, Santiago E, Walters J, Kirov G, Owen MJ, O'Donovan MC.

Am J Psychiatry. 2019 Aug 1;176(8):661-666. doi: 10.1176/appi.ajp.2018.18020140. Epub 2019 Jan 4.

PMID:
30606050
48.

Convergent Evidence That ZNF804A Is a Regulator of Pre-messenger RNA Processing and Gene Expression.

Chapman RM, Tinsley CL, Hill MJ, Forrest MP, Tansey KE, Pardiñas AF, Rees E, Doyle AM, Wilkinson LS, Owen MJ, O'Donovan MC, Blake DJ.

Schizophr Bull. 2019 Oct 24;45(6):1267-1278. doi: 10.1093/schbul/sby183.

49.

Integrative functional genomic analysis of human brain development and neuropsychiatric risks.

Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, Choi J, Muchnik S, Xu X, Wang D, Lorente-Galdos B, Liu S, Giusti-Rodríguez P, Won H, de Leeuw CA, Pardiñas AF; BrainSpan Consortium; PsychENCODE Consortium; PsychENCODE Developmental Subgroup, Hu M, Jin F, Li Y, Owen MJ, O'Donovan MC, Walters JTR, Posthuma D, Reimers MA, Levitt P, Weinberger DR, Hyde TM, Kleinman JE, Geschwind DH, Hawrylycz MJ, State MW, Sanders SJ, Sullivan PF, Gerstein MB, Lein ES, Knowles JA, Sestan N.

Science. 2018 Dec 14;362(6420). pii: eaat7615. doi: 10.1126/science.aat7615.

50.

Burden of disease, disability-adjusted life years and frailty prevalence.

O'Donovan MR, Sezgin D, Liew A, O'Caoimh R.

QJM. 2019 Apr 1;112(4):261-267. doi: 10.1093/qjmed/hcy291.

PMID:
30541151

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