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Items: 1 to 50 of 208

1.

Exacerbated brain edema in a rat streptozotocin model of hyperglycemic ischemic stroke: Evidence for involvement of blood-brain barrier Na-K-Cl cotransport and Na/H exchange.

Yuen NY, Chechneva OV, Chen YJ, Tsai YC, Little LK, Dang J, Tancredi DJ, Conston J, Anderson SE, O'Donnell ME.

J Cereb Blood Flow Metab. 2018 Jan 1:271678X18770844. doi: 10.1177/0271678X18770844. [Epub ahead of print]

PMID:
29739261
2.

The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism.

Li H, O'Donnell ME.

Bioessays. 2018 Mar;40(3). doi: 10.1002/bies.201700208. Epub 2018 Feb 6. Review.

PMID:
29405332
3.

The ring-shaped hexameric helicases that function at DNA replication forks.

O'Donnell ME, Li H.

Nat Struct Mol Biol. 2018 Feb;25(2):122-130. doi: 10.1038/s41594-018-0024-x. Epub 2018 Jan 29. Review.

PMID:
29379175
4.

Architecture of the Saccharomyces cerevisiae Replisome.

Bai L, Yuan Z, Sun J, Georgescu R, O'Donnell ME, Li H.

Adv Exp Med Biol. 2017;1042:207-228. doi: 10.1007/978-981-10-6955-0_10. Review.

5.

Replication fork convergence at termination: A multistep process.

Yao NY, O'Donnell ME.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):237-239. doi: 10.1073/pnas.1719825115. Epub 2017 Dec 19. No abstract available.

6.

Mutagenic cost of ribonucleotides in bacterial DNA.

Schroeder JW, Randall JR, Hirst WG, O'Donnell ME, Simmons LA.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11733-11738. doi: 10.1073/pnas.1710995114. Epub 2017 Oct 16. Erratum in: Proc Natl Acad Sci U S A. 2017 Nov 27;:.

7.

Single-molecule visualization of Saccharomyces cerevisiae leading-strand synthesis reveals dynamic interaction between MTC and the replisome.

Lewis JS, Spenkelink LM, Schauer GD, Hill FR, Georgescu RE, O'Donnell ME, van Oijen AM.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10630-10635. doi: 10.1073/pnas.1711291114. Epub 2017 Sep 18.

8.

Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks.

Langston LD, Mayle R, Schauer GD, Yurieva O, Zhang D, Yao NY, Georgescu RE, O'Donnell ME.

Elife. 2017 Sep 4;6. pii: e29118. doi: 10.7554/eLife.29118.

9.

Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.

Georgescu R, Yuan Z, Bai L, de Luna Almeida Santos R, Sun J, Zhang D, Yurieva O, Li H, O'Donnell ME.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E697-E706. doi: 10.1073/pnas.1620500114. Epub 2017 Jan 17.

10.

Quality control mechanisms exclude incorrect polymerases from the eukaryotic replication fork.

Schauer GD, O'Donnell ME.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):675-680. doi: 10.1073/pnas.1619748114. Epub 2017 Jan 9.

11.

Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest.

Bastia D, Srivastava P, Zaman S, Choudhury M, Mohanty BK, Bacal J, Langston LD, Pasero P, O'Donnell ME.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3639-48. doi: 10.1073/pnas.1607552113. Epub 2016 Jun 13. Erratum in: Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4577.

12.

Evolution of replication machines.

Yao NY, O'Donnell ME.

Crit Rev Biochem Mol Biol. 2016 May-Jun;51(3):135-49. doi: 10.3109/10409238.2015.1125845. Epub 2015 Dec 20. Review.

13.

Reply.

Wilson MA, O'Donnell ME, Cassivi SD.

Ann Thorac Surg. 2016 Mar;101(3):1238. doi: 10.1016/j.athoracsur.2015.08.013. No abstract available.

PMID:
26897217
14.

Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.

Yuan Z, Bai L, Sun J, Georgescu R, Liu J, O'Donnell ME, Li H.

Nat Struct Mol Biol. 2016 Mar;23(3):217-24. doi: 10.1038/nsmb.3170. Epub 2016 Feb 8.

15.

The architecture of a eukaryotic replisome.

Sun J, Shi Y, Georgescu RE, Yuan Z, Chait BT, Li H, O'Donnell ME.

Nat Struct Mol Biol. 2015 Dec;22(12):976-82. doi: 10.1038/nsmb.3113. Epub 2015 Nov 2.

16.

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation.

Georgescu RE, Schauer GD, Yao NY, Langston LD, Yurieva O, Zhang D, Finkelstein J, O'Donnell ME.

Elife. 2015 Apr 14;4:e04988. doi: 10.7554/eLife.04988.

17.

An unusual presentation of esophageal metastasis from breast cancer.

Wilson MA, Shah N, O'Donnell ME, Jaroszewski DE.

J Thorac Cardiovasc Surg. 2015 Jun;149(6):e110-2. doi: 10.1016/j.jtcvs.2015.02.038. Epub 2015 Feb 26. No abstract available.

18.

Thymic flap for bronchial stump reinforcement after lobectomy.

Wilson MA, Seder C, O'Donnell ME, Cassivi SD.

Ann Thorac Surg. 2015 Mar;99(3):1071-3. doi: 10.1016/j.athoracsur.2014.05.058.

PMID:
25742835
19.

Blood-brain barrier KCa3.1 channels: evidence for a role in brain Na uptake and edema in ischemic stroke.

Chen YJ, Wallace BK, Yuen N, Jenkins DP, Wulff H, O'Donnell ME.

Stroke. 2015 Jan;46(1):237-44. doi: 10.1161/STROKEAHA.114.007445. Epub 2014 Dec 4.

20.

CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication.

Langston LD, Zhang D, Yurieva O, Georgescu RE, Finkelstein J, Yao NY, Indiani C, O'Donnell ME.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15390-5. doi: 10.1073/pnas.1418334111. Epub 2014 Oct 13.

21.

Blood-brain barrier Na transporters in ischemic stroke.

O'Donnell ME.

Adv Pharmacol. 2014;71:113-46. doi: 10.1016/bs.apha.2014.06.011. Epub 2014 Aug 23. Review.

PMID:
25307215
22.

Portomesenteric venous thrombosis following major colon and rectal surgery: incidence and risk factors.

Robinson KA, O'Donnell ME, Pearson D, Kriegshauser JS, Odeleye M, Kalkbrenner K, Bodnar Z, Young-Fadok TM.

Surg Endosc. 2015 May;29(5):1071-9. doi: 10.1007/s00464-014-3788-z. Epub 2014 Aug 27.

PMID:
25159636
23.

Surgical and medical management of extracranial carotid artery aneurysms.

Fankhauser GT, Stone WM, Fowl RJ, O'Donnell ME, Bower TC, Meyer FB, Money SR.

J Vasc Surg. 2015 Feb;61(2):389-93. doi: 10.1016/j.jvs.2014.07.092. Epub 2014 Aug 21.

24.

Brachiocephalic vein bypass with sternal reconstruction for symptomatic occlusion.

O'Donnell ME, Jaroszewski DE, Coan K, Kazmier FJ, Money SR.

Ann Vasc Surg. 2014 Nov;28(8):1936.e5-8. doi: 10.1016/j.avsg.2014.07.010. Epub 2014 Aug 6.

PMID:
25108095
25.

Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork.

Georgescu RE, Langston L, Yao NY, Yurieva O, Zhang D, Finkelstein J, Agarwal T, O'Donnell ME.

Nat Struct Mol Biol. 2014 Aug;21(8):664-70. doi: 10.1038/nsmb.2851. Epub 2014 Jul 6.

26.

Do statins have a role in the promotion of postoperative wound healing in cardiac surgical patients?

Fitzmaurice GJ, McWilliams B, Nölke L, Redmond JM, McGuinness JG, O'Donnell ME.

Ann Thorac Surg. 2014 Aug;98(2):756-64. doi: 10.1016/j.athoracsur.2014.02.089. Epub 2014 Jun 28. Review.

PMID:
24980602
27.

A meta-analysis to compare Dacron versus polytetrafluroethylene grafts for above-knee femoropopliteal artery bypass.

Rychlik IJ, Davey P, Murphy J, O'Donnell ME.

J Vasc Surg. 2014 Aug;60(2):506-15. doi: 10.1016/j.jvs.2014.05.049. Epub 2014 Jun 25. Review.

28.

Content, accuracy and completeness of patient consent in a regional vascular surgery unit.

McGrogan D, Mark D, Lee B, O'Donnell ME.

Ir J Med Sci. 2015 Jun;184(2):521-9. doi: 10.1007/s11845-014-1160-x. Epub 2014 Jun 19.

PMID:
24942206
29.

Replisome mechanics: lagging strand events that influence speed and processivity.

Georgescu RE, Yao N, Indiani C, Yurieva O, O'Donnell ME.

Nucleic Acids Res. 2014 Jun;42(10):6497-510. doi: 10.1093/nar/gku257. Epub 2014 May 14.

30.

Endothelial function, antioxidant status and vascular compliance in newly diagnosed HFE C282Y homozygotes.

Cash WJ, O'Neill S, O'Donnell ME, McCance DR, Young IS, McEneny J, McDougall NI, Callender ME.

Adv Med Sci. 2014 Mar;59(1):28-33. doi: 10.1016/j.advms.2013.07.001. Epub 2014 Mar 15.

PMID:
24797970
31.

Implementation of best medical therapy for cardiovascular risk factors in vascular surgery patients treated in a tertiary referral regional unit.

McGrogan D, Mark D, Lee B, O'Donnell ME.

Int J Clin Pract. 2014 Sep;68(9):1100-9. doi: 10.1111/ijcp.12415. Epub 2014 Mar 25.

PMID:
24666966
32.

Ischemic factor-induced increases in cerebral microvascular endothelial cell Na/H exchange activity and abundance: evidence for involvement of ERK1/2 MAP kinase.

Yuen N, Lam TI, Wallace BK, Klug NR, Anderson SE, O'Donnell ME.

Am J Physiol Cell Physiol. 2014 May 15;306(10):C931-42. doi: 10.1152/ajpcell.00021.2013. Epub 2014 Mar 19.

33.

The impact of endovascular repair of ruptured abdominal aortic aneurysm on the gastrointestinal and renal function.

Makar RR, Badger SA, O'Donnell ME, Soong CV, Lau LL, Young IS, Hannon RJ, Lee B.

Int J Vasc Med. 2014;2014:178323. doi: 10.1155/2014/178323. Epub 2014 Jan 29.

34.

Glomus tumor of the mediastinum.

Rychlik IJ, O'Donnell ME, Davey P, Merard R, McGuigan J.

Asian Cardiovasc Thorac Ann. 2014 Jan;22(1):95-7. doi: 10.1177/0218492312472688. Epub 2013 Jul 16.

PMID:
24585654
35.

Percutaneous thrombolysis of acute-on-chronic inferior vena cava thrombosis after previous insertion of an Adams-DeWeese clip.

O'Donnell ME, Coan KE, Naidu SG, Shamoun FE, Money SR.

Vasc Endovascular Surg. 2014 May;48(4):342-5. doi: 10.1177/1538574414522330. Epub 2014 Feb 11.

PMID:
24518364
36.

Successful percutaneous management of ruptured middle colic aneurysm following endovascular aneurysm repair.

O'Donnell ME, Coan KE, Naidu SG, Money SR.

Vasc Endovascular Surg. 2014 Apr;48(3):283-4. doi: 10.1177/1538574413518612. Epub 2014 Jan 9. No abstract available.

PMID:
24407505
37.

Successful coil embolization of circumflex iliac artery pseudoaneurysms following paracentesis.

Day RW, Huettl EA, Naidu SG, Eversman WG, Douglas DD, O'Donnell ME.

Vasc Endovascular Surg. 2014 Apr;48(3):262-6. doi: 10.1177/1538574413518115. Epub 2014 Jan 6. Review.

PMID:
24399129
38.

The inflammatory response to ruptured abdominal aortic aneurysm is altered by endovascular repair.

Makar RR, Badger SA, O'Donnell ME, Soong CV, Lau LL, Young IS, Hannon RJ, Lee B.

Int J Vasc Med. 2013;2013:482728. doi: 10.1155/2013/482728. Epub 2013 Dec 2.

39.

In the time of significant generational diversity - surgical leadership must step up!

Money SR, O'Donnell ME, Gray RJ.

Surgeon. 2014 Feb;12(1):3-6. doi: 10.1016/j.surge.2013.09.007. Epub 2013 Sep 30.

PMID:
24090677
40.

Streptococcus bovis bacteraemia: an evaluation of the long-term effect on cardiac outcomes.

Fitzmaurice GJ, McKenna AJ, Murphy J, McMullan R, O'Donnell ME.

Gen Thorac Cardiovasc Surg. 2014 Mar;62(3):142-8. doi: 10.1007/s11748-013-0316-3. Epub 2013 Sep 11.

PMID:
24022385
41.

Disordered vascular compliance in haemochromatosis.

Cash WJ, O'Neill S, O'Donnell ME, McCance DR, Young IS, McEneny J, Cadden IS, McDougall NI, Callender ME.

Ir J Med Sci. 2014 Jun;183(2):303-9. doi: 10.1007/s11845-013-1010-2. Epub 2013 Sep 3.

PMID:
24000100
42.

DNA polymerases are error-prone at RecA-mediated recombination intermediates.

Pomerantz RT, Goodman MF, O'Donnell ME.

Cell Cycle. 2013 Aug 15;12(16):2558-63. doi: 10.4161/cc.25691. Epub 2013 Jul 29.

43.

Cost of rNTP/dNTP pool imbalance at the replication fork.

Yao NY, Schroeder JW, Yurieva O, Simmons LA, O'Donnell ME.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):12942-7. doi: 10.1073/pnas.1309506110. Epub 2013 Jul 23.

44.

Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination.

Pomerantz RT, Kurth I, Goodman MF, O'Donnell ME.

Nat Struct Mol Biol. 2013 Jun;20(6):748-55. doi: 10.1038/nsmb.2573. Epub 2013 May 19.

45.

Randomized controlled trial assessing the effect of simvastatin in primary biliary cirrhosis.

Cash WJ, O'Neill S, O'Donnell ME, McCance DR, Young IS, McEneny J, McDougall NI, Callender ME.

Liver Int. 2013 Sep;33(8):1166-74. doi: 10.1111/liv.12191. Epub 2013 May 15.

PMID:
23672463
46.

Bilateral pulmonary emboli secondary to indwelling hemodialysis reliable outflow catheter.

Coan KE, O'Donnell ME, Fankhauser GT, Bodnar Z, Chandrasekaran K, Stone WM.

Vasc Endovascular Surg. 2013 May;47(4):317-9. doi: 10.1177/1538574413484973. Epub 2013 Apr 8.

PMID:
23567802
47.

A solution to release twisted DNA during chromosome replication by coupled DNA polymerases.

Kurth I, Georgescu RE, O'Donnell ME.

Nature. 2013 Apr 4;496(7443):119-22. doi: 10.1038/nature11988. Epub 2013 Mar 27.

48.

RecA acts as a switch to regulate polymerase occupancy in a moving replication fork.

Indiani C, Patel M, Goodman MF, O'Donnell ME.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5410-5. doi: 10.1073/pnas.1303301110. Epub 2013 Mar 18.

49.

Inferior vena cava thrombosis: a review of current practice.

McAree BJ, O'Donnell ME, Fitzmaurice GJ, Reid JA, Spence RA, Lee B.

Vasc Med. 2013 Feb;18(1):32-43. doi: 10.1177/1358863X12471967. Review.

PMID:
23439778
50.

Cost-effectiveness of cilostazol, naftidrofuryl oxalate, and pentoxifylline for the treatment of intermittent claudication in people with peripheral arterial disease.

Meng Y, Squires H, Stevens JW, Simpson E, Harnan S, Thomas S, Michaels J, Stansby G, O'Donnell ME.

Angiology. 2014 Mar;65(3):190-7. doi: 10.1177/0003319712474335. Epub 2013 Jan 31.

PMID:
23378195

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