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Items: 1 to 50 of 72


A Role for Retrotransposon LINE-1 in Fetal Oocyte Attrition in Mice.

Malki S, van der Heijden GW, O'Donnell KA, Martin SL, Bortvin A.

Dev Cell. 2019 Dec 2;51(5):658. doi: 10.1016/j.devcel.2019.11.011. No abstract available.


Effect of a Sedation Weaning Protocol on Safety and Medication Use among Hospitalized Children Post Critical Illness.

Solodiuk JC, Greco CD, O'Donnell KA, Morrill DR, Curley MAQ.

J Pediatr Nurs. 2019 Nov - Dec;49:18-23. doi: 10.1016/j.pedn.2019.08.001. Epub 2019 Aug 27.


Ex Vivo Transposon-Mediated Genetic Screens for Cancer Gene Discovery.

O'Donnell KA, Guo Y, Suresh S, Updegraff BL, Zhou X.

Methods Mol Biol. 2019;1907:145-157. doi: 10.1007/978-1-4939-8967-6_12.


Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism.

Updegraff BL, Zhou X, Guo Y, Padanad MS, Chen PH, Yang C, Sudderth J, Rodriguez-Tirado C, Girard L, Minna JD, Mishra P, DeBerardinis RJ, O'Donnell KA.

Cell Rep. 2018 Nov 20;25(8):2223-2233.e6. doi: 10.1016/j.celrep.2018.10.100.


Modulation of Mutant KrasG12D -Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function.

Zhou X, Padanad MS, Evers BM, Smith B, Novaresi N, Suresh S, Richardson JA, Stein E, Zhu J, Hammer RE, O'Donnell KA.

Mol Cancer Res. 2019 Feb;17(2):594-603. doi: 10.1158/1541-7786.MCR-18-0739. Epub 2018 Nov 8.


Predictable, Preventable, and Deadly: Epidemic Carbon Monoxide Poisoning After Storms.

Henretig FM, Calello DP, Burns MM, O'Donnell KA, Osterhoudt KC.

Am J Public Health. 2018 Oct;108(10):1320-1321. doi: 10.2105/AJPH.2018.304619. No abstract available.


Correction: SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.

Suresh S, Durakoglugil D, Zhou X, Zhu B, Comerford SA, Xing C, Xie XJ, York B, O'Donnell KA.

PLoS Genet. 2018 Apr 11;14(4):e1007344. doi: 10.1371/journal.pgen.1007344. eCollection 2018 Apr.


Advances in functional genetic screening with transposons and CRISPR/Cas9 to illuminate cancer biology.

O'Donnell KA.

Curr Opin Genet Dev. 2018 Apr;49:85-94. doi: 10.1016/j.gde.2018.03.006. Epub 2018 Mar 26. Review.


Pediatric Toxicology: Household Product Ingestions.

O'Donnell KA.

Pediatr Ann. 2017 Dec 1;46(12):e449-e453. doi: 10.3928/19382359-20171120-04. Review.


Intraspecific adaptive radiation: Competition, ecological opportunity, and phenotypic diversification within species.

Levis NA, Martin RA, O'Donnell KA, Pfennig DW.

Evolution. 2017 Oct;71(10):2496-2509. doi: 10.1111/evo.13313. Epub 2017 Aug 25.


A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis.

Park SK, Zhou X, Pendleton KE, Hunter OV, Kohler JJ, O'Donnell KA, Conrad NK.

Cell Rep. 2017 Aug 1;20(5):1088-1099. doi: 10.1016/j.celrep.2017.07.017.


SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.

Suresh S, Durakoglugil D, Zhou X, Zhu B, Comerford SA, Xing C, Xie XJ, York B, O'Donnell KA.

PLoS Genet. 2017 Mar 8;13(3):e1006650. doi: 10.1371/journal.pgen.1006650. eCollection 2017 Mar. Erratum in: PLoS Genet. 2018 Apr 11;14 (4):e1007344.


Families as Partners in Hospital Error and Adverse Event Surveillance.

Khan A, Coffey M, Litterer KP, Baird JD, Furtak SL, Garcia BM, Ashland MA, Calaman S, Kuzma NC, O'Toole JK, Patel A, Rosenbluth G, Destino LA, Everhart JL, Good BP, Hepps JH, Dalal AK, Lipsitz SR, Yoon CS, Zigmont KR, Srivastava R, Starmer AJ, Sectish TC, Spector ND, West DC, Landrigan CP; the Patient and Family Centered I-PASS Study Group, Allair BK, Alminde C, Alvarado-Little W, Atsatt M, Aylor ME, Bale JF Jr, Balmer D, Barton KT, Beck C, Bismilla Z, Blankenburg RL, Chandler D, Choudhary A, Christensen E, Coghlan-McDonald S, Cole FS, Corless E, Cray S, Da Silva R, Dahale D, Dreyer B, Growdon AS, Gubler L, Guiot A, Harris R, Haskell H, Kocolas I, Kruvand E, Lane MM, Langrish K, Ledford CJW, Lewis K, Lopreiato JO, Maloney CG, Mangan A, Markle P, Mendoza F, Micalizzi DA, Mittal V, Obermeyer M, O'Donnell KA, Ottolini M, Patel SJ, Pickler R, Rogers JE, Sanders LM, Sauder K, Shah SS, Sharma M, Simpkin A, Subramony A, Thompson ED Jr, Trueman L, Trujillo T, Turmelle MP, Warnick C, Welch C, White AJ, Wien MF, Winn AS, Wintch S, Wolf M, Yin HS, Yu CE.

JAMA Pediatr. 2017 Apr 1;171(4):372-381. doi: 10.1001/jamapediatrics.2016.4812. Erratum in: JAMA Pediatr. 2018 Mar 1;172(3):302.


PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis.

Zhou X, Updegraff BL, Guo Y, Peyton M, Girard L, Larsen JE, Xie XJ, Zhou Y, Hwang TH, Xie Y, Rodriguez-Canales J, Villalobos P, Behrens C, Wistuba II, Minna JD, O'Donnell KA.

Cancer Res. 2017 Jan 1;77(1):187-197. doi: 10.1158/0008-5472.CAN-16-1267-T. Epub 2016 Nov 7.


Clinical effects of unintentional pediatric buprenorphine exposures: experience at a single tertiary care center.

Toce MS, Burns MM, O'Donnell KA.

Clin Toxicol (Phila). 2017 Jan;55(1):12-17. doi: 10.1080/15563650.2016.1244337. Epub 2016 Oct 19.


Hepatoblastoma modeling in mice places Nrf2 within a cancer field established by mutant β-catenin.

Comerford SA, Hinnant EA, Chen Y, Bansal H, Klapproth S, Rakheja D, Finegold MJ, Lopez-Terrada D, O'Donnell KA, Tomlinson GE, Hammer RE.

JCI Insight. 2016 Oct 6;1(16):e88549. doi: 10.1172/jci.insight.88549.


Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis.

Guo Y, Updegraff BL, Park S, Durakoglugil D, Cruz VH, Maddux S, Hwang TH, O'Donnell KA.

Cancer Res. 2016 Feb 15;76(4):773-86. doi: 10.1158/0008-5472.CAN-15-1697. Epub 2015 Dec 16.


Absolute calibration of a spectrometer using terrestrial solar radiation.

O'Donnell KA, Garces VG.

Appl Opt. 2015 Mar 20;54(9):2391-4. doi: 10.1364/AO.54.002391.


The maternal adversity, vulnerability and neurodevelopment project: theory and methodology.

O'Donnell KA, Gaudreau H, Colalillo S, Steiner M, Atkinson L, Moss E, Goldberg S, Karama S, Matthews SG, Lydon JE, Silveira PP, Wazana AD, Levitan RD, Sokolowski MB, Kennedy JL, Fleming A, Meaney MJ; MAVAN Research Team.

Can J Psychiatry. 2014 Sep;59(9):497-508. Review.


Better quality of mother-child interaction at 4 years of age decreases emotional overeating in IUGR girls.

Escobar RS, O'Donnell KA, Colalillo S, Pawlby S, Steiner M, Meaney MJ, Levitan RD, Silveira PP; MAVAN Study Team.

Appetite. 2014 Oct;81:337-42. doi: 10.1016/j.appet.2014.06.107. Epub 2014 Jul 8.


A role for retrotransposon LINE-1 in fetal oocyte attrition in mice.

Malki S, van der Heijden GW, O'Donnell KA, Martin SL, Bortvin A.

Dev Cell. 2014 Jun 9;29(5):521-533. doi: 10.1016/j.devcel.2014.04.027. Epub 2014 May 29. Erratum in: Dev Cell. 2019 Dec 2;51(5):658.


Stressing the importance of CHOP in liver cancer.

Updegraff BL, O'Donnell KA.

PLoS Genet. 2013;9(12):e1004045. doi: 10.1371/journal.pgen.1004045. Epub 2013 Dec 19. No abstract available.


Controlled insertional mutagenesis using a LINE-1 (ORFeus) gene-trap mouse model.

O'Donnell KA, An W, Schrum CT, Wheelan SJ, Boeke JD.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):E2706-13. doi: 10.1073/pnas.1302504110. Epub 2013 Jul 1.


Poly(A) binding protein C1 is essential for efficient L1 retrotransposition and affects L1 RNP formation.

Dai L, Taylor MS, O'Donnell KA, Boeke JD.

Mol Cell Biol. 2012 Nov;32(21):4323-36. doi: 10.1128/MCB.06785-11. Epub 2012 Aug 20.


A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.

O'Donnell KA, Keng VW, York B, Reineke EL, Seo D, Fan D, Silverstein KA, Schrum CT, Xie WR, Mularoni L, Wheelan SJ, Torbenson MS, O'Malley BW, Largaespada DA, Boeke JD.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):E1377-86. doi: 10.1073/pnas.1115433109. Epub 2012 May 3.


A fast and accessible methodology for micro-patterning cells on standard culture substrates using Parafilm™ inserts.

Javaherian S, O'Donnell KA, McGuigan AP.

PLoS One. 2011;6(6):e20909. doi: 10.1371/journal.pone.0020909. Epub 2011 Jun 7.


Observations of dispersion cancellation of entangled photon pairs.

O'Donnell KA.

Phys Rev Lett. 2011 Feb 11;106(6):063601. Epub 2011 Feb 11.


Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs.

An W, Dai L, Niewiadomska AM, Yetil A, O'Donnell KA, Han JS, Boeke JD.

Mob DNA. 2011 Feb 14;2(1):2. doi: 10.1186/1759-8753-2-2.


Mobilizing diversity: transposable element insertions in genetic variation and disease.

O'Donnell KA, Burns KH.

Mob DNA. 2010 Sep 2;1(1):21. doi: 10.1186/1759-8753-1-21.


Time-resolved up-conversion of entangled photon pairs.

O'Donnell KA, U'Ren AB.

Phys Rev Lett. 2009 Sep 18;103(12):123602. Epub 2009 Sep 18.


Huffing and puffing to lose weight.

O'Donnell KA, Ewald MB.

Pediatr Emerg Care. 2009 Sep;25(9):605-7. doi: 10.1097/PEC.0b013e3181b51e13. No abstract available.


Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model.

Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT.

Cell. 2009 Jun 12;137(6):1005-17. doi: 10.1016/j.cell.2009.04.021.


Plug and play modular strategies for synthetic retrotransposons.

An W, Davis ES, Thompson TL, O'Donnell KA, Lee CY, Boeke JD.

Methods. 2009 Nov;49(3):227-35. doi: 10.1016/j.ymeth.2009.05.013. Epub 2009 May 28.


Obtundation and seizure following ondansetron overdose in an infant.

George M, Al-Duaij N, O'Donnell KA, Shannon MW.

Clin Toxicol (Phila). 2008 Dec;46(10):1064-6. doi: 10.1080/15563650802304401.


A descent into the nuage: the maelstrom of transposon control.

O'Donnell KA, Burns KH, Boeke JD.

Dev Cell. 2008 Aug;15(2):179-81. doi: 10.1016/j.devcel.2008.07.016.


Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae.

Ben-Aroya S, Coombes C, Kwok T, O'Donnell KA, Boeke JD, Hieter P.

Mol Cell. 2008 Apr 25;30(2):248-58. doi: 10.1016/j.molcel.2008.02.021.


Domesticated DNA transposon proteins mediate retrotransposon control.

O'Donnell KA, Boeke JD.

Cell Res. 2008 Mar;18(3):331-3. doi: 10.1038/cr.2008.34. Review. No abstract available.


Mighty Piwis defend the germline against genome intruders.

O'Donnell KA, Boeke JD.

Cell. 2007 Apr 6;129(1):37-44. Review.


Observation of ultrabroadband, beamlike parametric downconversion.

O'Donnell KA, U'Ren AB.

Opt Lett. 2007 Apr 1;32(7):817-9.


The c-Myc target gene network.

Dang CV, O'Donnell KA, Zeller KI, Nguyen T, Osthus RC, Li F.

Semin Cancer Biol. 2006 Aug;16(4):253-64. Epub 2006 Jul 25. Review.


Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis.

O'Donnell KA, Yu D, Zeller KI, Kim JW, Racke F, Thomas-Tikhonenko A, Dang CV.

Mol Cell Biol. 2006 Mar;26(6):2373-86.


The great MYC escape in tumorigenesis.

Dang CV, O'donnell KA, Juopperi T.

Cancer Cell. 2005 Sep;8(3):177-8. Review.


Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis.

Li F, Wang Y, Zeller KI, Potter JJ, Wonsey DR, O'Donnell KA, Kim JW, Yustein JT, Lee LA, Dang CV.

Mol Cell Biol. 2005 Jul;25(14):6225-34.


c-Myc-regulated microRNAs modulate E2F1 expression.

O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT.

Nature. 2005 Jun 9;435(7043):839-43.


Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays.

Kim JW, Zeller KI, Wang Y, Jegga AG, Aronow BJ, O'Donnell KA, Dang CV.

Mol Cell Biol. 2004 Jul;24(13):5923-36.


Irish strains of Neisseria meningitidis: characterisation using multilocus sequence typing.

Murphy KM, O'Donnell KA, Higgins AB, O'Neill C, Cafferkey MT.

Br J Biomed Sci. 2003;60(4):204-9.


Enhanced specular peaks in diffuse light scattering from weakly rough metal surfaces.

O'Donnell KA, Méndez ER.

J Opt Soc Am A Opt Image Sci Vis. 2003 Dec;20(12):2338-46.


An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets.

Zeller KI, Jegga AG, Aronow BJ, O'Donnell KA, Dang CV.

Genome Biol. 2003;4(10):R69. Epub 2003 Sep 11.


The mutation spectrum of hyperphenylalaninaemia in the Republic of Ireland: the population history of the Irish revisited.

O'Donnell KA, O'Neill C, Tighe O, Bertorelle G, Naughten E, Mayne PD, Croke DT.

Eur J Hum Genet. 2002 Sep;10(9):530-8.


Adolescent views of diabetes-related parent conflict and support: a focus group analysis.

Weinger K, O'Donnell KA, Ritholz MD.

J Adolesc Health. 2001 Nov;29(5):330-6.

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