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Protection from amyloid β peptide-induced memory, biochemical and morphological deficits by a phosphodiesterase-4D (PDE4D) allosteric inhibitor.

Cui SY, Yang MX, Zhang YH, Zheng V, Zhang HT, Gurney ME, Xu Y, O'Donnell JM.

J Pharmacol Exp Ther. 2019 Sep 5. pii: jpet.119.259986. doi: 10.1124/jpet.119.259986. [Epub ahead of print]


Innate immune responses to paraquat exposure in a Drosophila model of Parkinson's disease.

Maitra U, Scaglione MN, Chtarbanova S, O'Donnell JM.

Sci Rep. 2019 Sep 3;9(1):12714. doi: 10.1038/s41598-019-48977-6.


Single housing-induced effects in cognitive impairment and depression-like behavior in male and female mice involve neuroplasticity related signaling.

Liu N, Wang Y, An AY, Banker C, Qian Y, O'Donnell JM.

Eur J Neurosci. 2019 Aug 31. doi: 10.1111/ejn.14565. [Epub ahead of print]


Impact of Adrenal Hormone Supplementation on Bone Geometry in Growing Teens With Anorexia Nervosa.

DiVasta AD, Feldman HA, O'Donnell JM, Long J, Leonard MB, Gordon CM.

J Adolesc Health. 2019 Jun 18. pii: S1054-139X(19)30200-9. doi: 10.1016/j.jadohealth.2019.04.003. [Epub ahead of print]


Physician Versus Nonphysician Instruction: Evaluating an Expert Curriculum-Competent Facilitator Model for Simulation-Based Central Venous Catheter Training.

Musits AN, Phrampus PE, Lutz JW, Bear TM, Maximous SI, Mrkva AJ, OʼDonnell JM.

Simul Healthc. 2019 Aug;14(4):228-234. doi: 10.1097/SIH.0000000000000374.


Preserving the chondrolabral junction reduces the rate of capsular adhesions.

Webb MSL, Devitt BM, O'Donnell JM.

J Hip Preserv Surg. 2019 Mar 19;6(1):50-54. doi: 10.1093/jhps/hnz005. eCollection 2019 Jan.


The antidepressant- and anxiolytic-like effects of resveratrol: Involvement of phosphodiesterase-4D inhibition.

Zhu X, Li W, Li Y, Xu W, Yuan Y, Zheng V, Zhang H, O'Donnell JM, Xu Y, Yin X.

Neuropharmacology. 2019 Jul 15;153:20-31. doi: 10.1016/j.neuropharm.2019.04.022. Epub 2019 Apr 24.


Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders.

Gurney ME, Nugent RA, Mo X, Sindac JA, Hagen TJ, Fox D 3rd, O'Donnell JM, Zhang C, Xu Y, Zhang HT, Groppi VE, Bailie M, White RE, Romero DL, Vellekoop AS, Walker JR, Surman MD, Zhu L, Campbell RF.

J Med Chem. 2019 May 23;62(10):4884-4901. doi: 10.1021/acs.jmedchem.9b00193. Epub 2019 Apr 23.


Preequilibrium Asymmetries in the ^{239}Pu(n,f) Prompt Fission Neutron Spectrum.

Kelly KJ, Kawano T, O'Donnell JM, Gomez JA, Devlin M, Neudecker D, Talou P, Lovell AE, White MC, Haight RC, Taddeucci TN, Mosby SM, Lee HY, Wu CY, Henderson R, Henderson J, Buckner MQ.

Phys Rev Lett. 2019 Feb 22;122(7):072503. doi: 10.1103/PhysRevLett.122.072503.


Reduced phosphodiesterase-2 activity in the amygdala results in anxiolytic-like effects on behavior in mice.

Chen L, Cui S, Yu H, Li G, Liu N, Wu Q, Zhang HT, O'Donnell JM, Wang G, Xu Y.

J Psychopharmacol. 2019 May;33(5):568-576. doi: 10.1177/0269881119832753. Epub 2019 Mar 5.


Comparing outcome scales for unruptured intracranial aneurysms: A prospective cohort study.

Morgan MK, O'Donnell JM, Heller GZ, Rogers JM.

J Clin Neurosci. 2018 Dec;58:56-63. doi: 10.1016/j.jocn.2018.10.064. Epub 2018 Oct 23.


Breaking Down Barriers to Pharmacy Graduate Education: The Report of the 2017-2018 Research and Graduate Affairs Committee.

Poloyac SM, Cavanaugh JE, Hagemeier NE, Kumar K, Melchert RB, O'Donnell JM, Priefer R, Touchette DR, Farrell DF, Block KF.

Am J Pharm Educ. 2018 Sep;82(7):7147. doi: 10.5688/ajpe7147.


Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior.

Huang X, Xiaokaiti Y, Yang J, Pan J, Li Z, Luria V, Li Y, Song G, Zhu X, Zhang HT, O'Donnell JM, Xu Y.

Neuropharmacology. 2018 Dec;143:176-185. doi: 10.1016/j.neuropharm.2018.09.039. Epub 2018 Sep 27.


Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice.

Zhang C, Xu Y, Chowdhary A, Fox D 3rd, Gurney ME, Zhang HT, Auerbach BD, Salvi RJ, Yang M, Li G, O'Donnell JM.

Neuropsychopharmacology. 2018 Oct;43(11):2299-2309. doi: 10.1038/s41386-018-0178-6. Epub 2018 Aug 14.


Randomized Controlled Trial of Hip Arthroscopy Surgery vs Physical Therapy: Letter to the Editor.

Faucett SC, Nepple JJ, Andrade T, Aoki S, Bedi A, Bharam S, Brick MJ, Byrd JWT, Cakic JN, Cascio BM, Christoforetti J, Clohisy JC, Domb B, Dumont G, Ellman MB, Harris JD, Kelly BT, Krych AJ, LaPrade RF, Larson C, Laskowski JR, Levy BA, Lynch TS, Martin HD, Mather C 3rd, Miyamoto RG, Nho SJ, O'Donnell JM, Philippon MJ, Price MR, Ranawat AS, Rodriguez MC, Safran MR, Said HG, Salata MJ, Sampson T, Stubbs AJ, Uchida S, Villar RN, Willimon SC, Wolf A, Wong I, Wuerz TH, Yen YM.

Am J Sports Med. 2018 Jul;46(8):NP35-NP38. doi: 10.1177/0363546518777483. No abstract available.


Inhibition of phosphodiesterase 2 by Bay 60-7550 decreases ethanol intake and preference in mice.

Shi J, Liu H, Pan J, Chen J, Zhang N, Liu K, Fei N, O'Donnell JM, Zhang HT, Xu Y.

Psychopharmacology (Berl). 2018 Aug;235(8):2377-2385. doi: 10.1007/s00213-018-4934-4. Epub 2018 Jun 7.


A novel and simple classification for ligamentum teres pathology based on joint hypermobility.

O'Donnell JM, Arora M.

J Hip Preserv Surg. 2017 Oct 16;5(2):113-118. doi: 10.1093/jhps/hnx039. eCollection 2018 Jul. Review.


An Exploratory Study of Sectra Table Visualization Improves the Effectiveness of Emergency Bedside Echocardiography Training.

Shi D, Walline JH, Liu J, Yu X, Xu J, Song PP, Zhu H, O'Donnell JM.

J Ultrasound Med. 2019 Feb;38(2):363-370. doi: 10.1002/jum.14696. Epub 2018 May 21.


A novel PDE9 inhibitor WYQ-C36D ameliorates corticosterone-induced neurotoxicity and depression-like behaviors by cGMP-CREB-related signaling.

Huang XF, Jiang WT, Liu L, Song FC, Zhu X, Shi GL, Ding SM, Ke HM, Wang W, O'Donnell JM, Zhang HT, Luo HB, Wan YQ, Song GQ, Xu Y.

CNS Neurosci Ther. 2018 Oct;24(10):889-896. doi: 10.1111/cns.12864. Epub 2018 May 2.


The neuroprotective and antidepressant-like effects of Hcyb1, a novel selective PDE2 inhibitor.

Liu L, Zheng J, Huang XF, Zhu X, Ding SM, Ke HM, O'Donnell JM, Zhang HT, Song GQ, Xu Y.

CNS Neurosci Ther. 2018 Jul;24(7):652-660. doi: 10.1111/cns.12863. Epub 2018 Apr 27.


Functional outcomes and quality of life after microsurgical clipping of unruptured intracranial aneurysms: a prospective cohort study.

O'Donnell JM, Morgan MK, Manuguerra M.

J Neurosurg. 2018 Mar 2;130(1):278-285. doi: 10.3171/2017.8.JNS171576.


Magnetic resonance imaging and spectroscopy evidence of efficacy for adrenal and gonadal hormone replacement therapy in anorexia nervosa.

Vajapeyam S, Ecklund K, Mulkern RV, Feldman HA, O'Donnell JM, DiVasta AD, Rosen CJ, Gordon CM.

Bone. 2018 May;110:335-342. doi: 10.1016/j.bone.2018.02.021. Epub 2018 Feb 26.


The role of the ligamentum teres in the adult hip: redundant or relevant? A review.

O'Donnell JM, Devitt BM, Arora M.

J Hip Preserv Surg. 2018 Jan 10;5(1):15-22. doi: 10.1093/jhps/hnx046. eCollection 2018 Jan. Review.


Enhanced Redox State and Efficiency of Glucose Oxidation With miR Based Suppression of Maladaptive NADPH-Dependent Malic Enzyme 1 Expression in Hypertrophied Hearts.

Lahey R, Carley AN, Wang X, Glass CE, Accola KD, Silvestry S, O'Donnell JM, Lewandowski ED.

Circ Res. 2018 Mar 16;122(6):836-845. doi: 10.1161/CIRCRESAHA.118.312660. Epub 2018 Jan 31.


Quality of life and disability 12 months after surgery vs. conservative management for unruptured brain arteriovenous malformations: Scottish population-based and Australian hospital-based studies.

O'Donnell JM, Al-Shahi Salman R, Manuguerra M, Assaad N, Morgan MK.

Acta Neurochir (Wien). 2018 Mar;160(3):559-566. doi: 10.1007/s00701-017-3451-2. Epub 2018 Jan 11.


Competency, Programming, and Emerging Innovation in Graduate Education within Schools of Pharmacy: The Report of the 2016-2017 Research and Graduate Affairs Committee.

Poloyac SM, Block KF, Cavanaugh JE, Dwoskin LP, Melchert RB, Nemire RE, O'Donnell JM, Priefer R, Touchette DR.

Am J Pharm Educ. 2017 Oct;81(8):S11. doi: 10.5688/ajpeS11.


The Role of Phosphodiesterase-2 in Psychiatric and Neurodegenerative Disorders.

Zhang C, Lueptow LM, Zhang HT, O'Donnell JM, Xu Y.

Adv Neurobiol. 2017;17:307-347. doi: 10.1007/978-3-319-58811-7_12. Review.


Modulation of social space by dopamine in Drosophila melanogaster, but no effect on the avoidance of the Drosophila stress odorant.

Fernandez RW, Akinleye AA, Nurilov M, Feliciano O, Lollar M, Aijuri RR, O'Donnell JM, Simon AF.

Biol Lett. 2017 Aug;13(8). pii: 20170369. doi: 10.1098/rsbl.2017.0369.


The reliability of commonly used arthroscopic classifications of ligamentum teres pathology.

Devitt BM, Smith B, Stapf R, Jo S, O'Donnell JM.

J Hip Preserv Surg. 2017 Mar 5;4(2):187-193. doi: 10.1093/jhps/hnx005. eCollection 2017 Jul.


Generalized Joint Hypermobility Is Predictive of Hip Capsular Thickness.

Devitt BM, Smith BN, Stapf R, Tacey M, O'Donnell JM.

Orthop J Sports Med. 2017 Apr 19;5(4):2325967117701882. doi: 10.1177/2325967117701882. eCollection 2017 Apr.


Bone marrow fat content in 70 adolescent girls with anorexia nervosa: Magnetic resonance imaging and magnetic resonance spectroscopy assessment.

Ecklund K, Vajapeyam S, Mulkern RV, Feldman HA, O'Donnell JM, DiVasta AD, Gordon CM.

Pediatr Radiol. 2017 Jul;47(8):952-962. doi: 10.1007/s00247-017-3856-3. Epub 2017 Apr 22.


Multiphasic Regulation of Systemic and Peripheral Organ Metabolic Responses to Cardiac Hypertrophy.

Liew CW, Xu S, Wang X, McCann M, Whang Kong H, Carley AC, Pang J, Fantuzzi G, O'Donnell JM, Lewandowski ED.

Circ Heart Fail. 2017 Apr;10(4). pii: e003864. doi: 10.1161/CIRCHEARTFAILURE.117.003864.


The Risk of Seizure Following Surgery for Brain Arteriovenous Malformation: A Prospective Cohort Study.

O'Donnell JM, Morgan MK, Heller GZ.

Neurosurgery. 2017 Dec 1;81(6):935-948. doi: 10.1093/neuros/nyx101.


Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.

Crabtree GW, Sun Z, Kvajo M, Broek JA, Fénelon K, McKellar H, Xiao L, Xu B, Bahn S, O'Donnell JM, Gogos JA.

J Neurosci. 2017 Apr 12;37(15):4158-4180. doi: 10.1523/JNEUROSCI.4345-15.2017. Epub 2017 Mar 10.


Disruption of dopamine homeostasis has sexually dimorphic effects on senescence characteristics of Drosophila melanogaster.

Bednářová A, Hanna ME, Rakshit K, O'Donnell JM, Krishnan N.

Eur J Neurosci. 2017 Mar;45(6):816-825. doi: 10.1111/ejn.13525. Epub 2017 Feb 7.


Use of personal protective equipment among health care personnel: Results of clinical observations and simulations.

Kang J, O'Donnell JM, Colaianne B, Bircher N, Ren D, Smith KJ.

Am J Infect Control. 2017 Jan 1;45(1):17-23. doi: 10.1016/j.ajic.2016.08.011.


Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System.

Zhang C, Xu Y, Zhang HT, Gurney ME, O'Donnell JM.

Sci Rep. 2017 Jan 5;7:40115. doi: 10.1038/srep40115.


Use of dual energy X-ray absorptiometry in pediatric patients.

Wasserman H, O'Donnell JM, Gordon CM.

Bone. 2017 Nov;104:84-90. doi: 10.1016/j.bone.2016.12.008. Epub 2016 Dec 15.


Effect of Exercise and Antidepressants on Skeletal Outcomes in Adolescent Girls With Anorexia Nervosa.

DiVasta AD, Feldman HA, O'Donnell JM, Long J, Leonard MB, Gordon CM.

J Adolesc Health. 2017 Feb;60(2):229-232. doi: 10.1016/j.jadohealth.2016.10.003. Epub 2016 Dec 6.


Prospective study of nerve injuries associated with hip arthroscopy in the lateral position using the modified portals.

Salas AP, O'Donnell JM.

J Hip Preserv Surg. 2016 Nov 10;3(4):278-287. doi: 10.1093/jhps/hnw032. eCollection 2016 Oct.


Virtually Nursing: Emerging Technologies in Nursing Education.

Foronda CL, Alfes CM, Dev P, Kleinheksel AJ, Nelson DA Jr, OʼDonnell JM, Samosky JT.

Nurse Educ. 2017 Jan/Feb;42(1):14-17.


Skeletal outcomes by peripheral quantitative computed tomography and dual-energy X-ray absorptiometry in adolescent girls with anorexia nervosa.

DiVasta AD, Feldman HA, O'Donnell JM, Long J, Leonard MB, Gordon CM.

Osteoporos Int. 2016 Dec;27(12):3549-3558. Epub 2016 Jul 8.


Airway Management: A Structured Curriculum for Critical Care Transport Providers.

Kuszajewski ML, O'Donnell JM, Phrampus PE, Robey WC 3rd, Tuite PK.

Air Med J. 2016 May-Jun;35(3):138-42. doi: 10.1016/j.amj.2015.12.013. Epub 2016 Apr 16.


Enhanced incorporation of dietary DHA into lymph phospholipids by altering its molecular carrier.

Subbaiah PV, Dammanahalli KJ, Yang P, Bi J, O'Donnell JM.

Biochim Biophys Acta. 2016 Aug;1861(8 Pt A):723-9. doi: 10.1016/j.bbalip.2016.05.002. Epub 2016 May 10.


Rapid Development and Deployment of Ebola Readiness Training Across an Academic Health System: The Critical Role of Simulation Education, Consulting, and Systems Integration.

Phrampus PE, O'Donnell JM, Farkas D, Abernethy D, Brownlee K, Dongilli T, Martin S.

Simul Healthc. 2016 Apr;11(2):82-8. doi: 10.1097/SIH.0000000000000137.


Avulsion of the direct head of rectus femoris following arthroscopic subspine impingement resection: a case report.

Devitt BM, Smith B, Stapf R, O'Donnell JM.

J Hip Preserv Surg. 2015 Dec 16;3(1):56-60. doi: 10.1093/jhps/hnv072. eCollection 2016 Apr.


Ligamentum teres injuries - an observational study of a proposed new arthroscopic classification.

Porthos Salas A, O'Donnell JM.

J Hip Preserv Surg. 2015 Jul 1;2(3):258-64. doi: 10.1093/jhps/hnv045. eCollection 2015 Oct.


Endoscopic lesser trochanter resection for treatment of ischiofemoral impingement.

Jo S, O'Donnell JM.

J Hip Preserv Surg. 2015 Jul;2(2):184-9. doi: 10.1093/jhps/hnv019. Epub 2015 Mar 30. Review.


The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling.

Wang G, Chen L, Pan X, Chen J, Wang L, Wang W, Cheng R, Wu F, Feng X, Yu Y, Zhang HT, O'Donnell JM, Xu Y.

Oncotarget. 2016 Apr 5;7(14):17380-92. doi: 10.18632/oncotarget.8041.


The Risk of Seizure After Surgery for Unruptured Intracranial Aneurysms: A Prospective Cohort Study.

OʼDonnell JM, Morgan MK, Bervini D, Heller GZ, Assaad N.

Neurosurgery. 2016 Aug;79(2):222-30. doi: 10.1227/NEU.0000000000001176.


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