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Items: 1 to 50 of 250

1.

Severe Exertional Dyspnea in an Ex-Smoker with a Large Apical Bulla.

Elbehairy AF, Faisal A, Ciavaglia CE, Kwok C, Reid K, Vincent SG, Domnik NJ, Neder JA, O'Donnell DE.

Ann Am Thorac Soc. 2018 Oct;15(10):1221-1228. doi: 10.1513/AnnalsATS.201804-288CC. No abstract available.

PMID:
30272494
2.

Heart or Lungs? Uncovering the Causes of Exercise Intolerance in a Patient with Chronic Cardiopulmonary Disease.

Rocha A, Arbex FF, Sperandio PA, Mancuso F, Alencar MCN, Souza A, Biazzim L, O'Donnell DE, Neder JA.

Ann Am Thorac Soc. 2018 Sep;15(9):1096-1104. doi: 10.1513/AnnalsATS.201802-073CC. No abstract available.

PMID:
30168743
3.

Current challenges in managing comorbid heart failure and COPD.

Neder JA, Rocha A, Alencar MCN, Arbex F, Berton DC, Oliveira MF, Sperandio PA, Nery LE, O'Donnell DE.

Expert Rev Cardiovasc Ther. 2018 Sep;16(9):653-673. doi: 10.1080/14779072.2018.1510319. Epub 2018 Sep 3.

PMID:
30099925
4.

The diagnostic performance of patient symptoms in screening for COPD.

Johnson KM, Tan WC, Bourbeau J, Sin DD, Sadatsafavi M; Canadian Cohort of Obstructive Lung Disease (CanCOLD) study and the Canadian Respiratory Research Network.

Respir Res. 2018 Aug 3;19(1):147. doi: 10.1186/s12931-018-0853-5.

5.

Serotonergic antidepressant use and morbidity and mortality among older adults with COPD.

Vozoris NT, Wang X, Austin PC, Stephenson AL, O'Donnell DE, Gershon AS, Gill SS, Rochon PA.

Eur Respir J. 2018 Jul 27;52(1). pii: 1800475. doi: 10.1183/13993003.00475-2018. Print 2018 Jul.

PMID:
29946006
6.

Increasing Physical Activity in COPD One Step at a Time.

O'Donnell DE.

Am J Respir Crit Care Med. 2018 May 14. doi: 10.1164/rccm.201804-0755ED. [Epub ahead of print] No abstract available.

PMID:
29758168
7.

Correction to: Long-acting bronchodilators improve exercise capacity in COPD patients: a systematic review and meta-analysis.

Di Marco F, Sotgiu G, Santus P, O'Donnell DE, Beeh KM, Dore S, Roggi MA, Giuliani L, Blasi F, Centanni S.

Respir Res. 2018 Apr 24;19(1):70. doi: 10.1186/s12931-018-0764-5.

8.

Acute bronchodilator therapy does not reduce wasted ventilation during exercise in COPD.

Elbehairy AF, Webb KA, Laveneziana P, Domnik NJ, Neder JA, O'Donnell DE; Canadian Respiratory Research Network (CRRN).

Respir Physiol Neurobiol. 2018 Jun;252-253:64-71. doi: 10.1016/j.resp.2018.03.012. Epub 2018 Mar 22.

PMID:
29578103
9.

Inspiratory muscle training reduces diaphragm activation and dyspnea during exercise in COPD.

Langer D, Ciavaglia C, Faisal A, Webb KA, Neder JA, Gosselink R, Dacha S, Topalovic M, Ivanova A, O'Donnell DE.

J Appl Physiol (1985). 2018 Aug 1;125(2):381-392. doi: 10.1152/japplphysiol.01078.2017. Epub 2018 Mar 15.

PMID:
29543134
10.

Systemic vascular dysfunction is associated with emphysema burden in mild COPD.

Zelt JT, Jones JH, Hirai DM, King TJ, Berton DC, Pyke KE, O'Donnell DE, Neder JA.

Respir Med. 2018 Mar;136:29-36. doi: 10.1016/j.rmed.2018.01.007. Epub 2018 Jan 12.

PMID:
29501244
11.

A Simplified Approach to Select Exercise Endurance Intensity for Interventional Studies in COPD.

Degani-Costa LH, O'Donnell DE, Webb K, Aranda LC, Carlstron JP, Cesar TDS, Plachi F, Berton DC, Neder JA, Nery LE.

COPD. 2018 Apr;15(2):139-147. doi: 10.1080/15412555.2018.1428944. Epub 2018 Feb 27.

PMID:
29485343
12.

Effect of tiotropium on spontaneous expiratory flow-volume curves during exercise in GOLD 1-2 COPD.

Porszasz J, Carraro N, Cao R, Gore A, Ma S, Jiang T, Maltais F, Ferguson GT, O'Donnell DE, Shaikh A, Rossiter HB, Casaburi R.

Respir Physiol Neurobiol. 2018 May;251:8-15. doi: 10.1016/j.resp.2018.02.006. Epub 2018 Feb 10.

PMID:
29438808
13.

Excess ventilation in COPD: Implications for dyspnoea and tolerance to interval exercise.

Bravo DM, Gimenes AC, Amorim BC, Alencar MC, Berton DC, O'Donnell DE, Nery LE, Neder JA.

Respir Physiol Neurobiol. 2018 Apr;250:7-13. doi: 10.1016/j.resp.2018.01.013. Epub 2018 Jan 31.

PMID:
29382565
14.

Long-acting bronchodilators improve exercise capacity in COPD patients: a systematic review and meta-analysis.

Di Marco F, Sotgiu G, Santus P, O'Donnell DE, Beeh KM, Dore S, Roggi MA, Giuliani L, Blasi F, Centanni S.

Respir Res. 2018 Jan 24;19(1):18. doi: 10.1186/s12931-018-0721-3. Erratum in: Respir Res. 2018 Apr 24;19(1):70.

15.

Unraveling the Cause of Severe Exertional Dyspnea in a Heavy Smoker.

Elbehairy AF, Hockmann K, Ciavaglia CE, Faisal A, Hill E, Webb KA, Neder JA, O'Donnell DE.

Ann Am Thorac Soc. 2017 Dec;14(12):1849-1855. doi: 10.1513/AnnalsATS.201705-382CC. No abstract available.

PMID:
29192822
16.

Redefining Cut-Points for High Symptom Burden of the Global Initiative for Chronic Obstructive Lung Disease Classification in 18,577 Patients With Chronic Obstructive Pulmonary Disease.

Smid DE, Franssen FME, Gonik M, Miravitlles M, Casanova C, Cosio BG, de Lucas-Ramos P, Marin JM, Martinez C, Mir I, Soriano JB, de Torres JP, Agusti A, Atalay NB, Billington J, Boutou AK, Brighenti-Zogg S, Chaplin E, Coster S, Dodd JW, Dürr S, Fernandez-Villar A, Groenen MTJ, Guimarães M, Hejduk K, Higgins V, Hopkinson NS, Horita N, Houben-Wilke S, Janssen DJA, Jehn M, Joerres R, Karch A, Kelly JL, Kim YI, Kimura H, Koblizek V, Kocks JH, Kon SSC, Kwon N, Ladeira I, Lee SD, Leuppi JD, Locantore N, Lopez-Campos JL, D-C Man W, Maricic L, Mendoza L, Miedinger D, Mihaltan F, Minami S, van der Molen T, Murrells TJ, Nakken N, Nishijima Y, Norman IJ, Novotna B, O'Donnell DE, Ogata Y, Pereira ED, Piercy J, Price D, Pothirat C, Raghavan N, Ringbaek T, Sajkov D, Sigari N, Singh S, Small M, da Silva GF, Tanner RJ, Tsiligianni IG, Tulek B, Tzanakis N, Vanfleteren LEGW, Watz H, Webb KA, Wouters EFM, Xie GG, Yoshikawa M, Spruit MA.

J Am Med Dir Assoc. 2017 Dec 1;18(12):1097.e11-1097.e24. doi: 10.1016/j.jamda.2017.09.003. Review.

PMID:
29169740
17.

Activity-Related Dyspnoea in Chronic Pulmonary Diseases: New Mechanistic Insights.

O'Donnell DE.

Tanaffos. 2017;16(Suppl 1):S5-S6. No abstract available.

18.

"Mild" COPD: What Spirometry Conceals!

O'Donnell DE.

Tanaffos. 2017;16(Suppl 1):S4. No abstract available.

19.

Incident diuretic drug use and adverse respiratory events among older adults with chronic obstructive pulmonary disease.

Vozoris NT, Wang X, Austin PC, O'Donnell DE, Aaron SD, To TM, Gershon AS.

Br J Clin Pharmacol. 2018 Mar;84(3):579-589. doi: 10.1111/bcp.13465. Epub 2017 Dec 6.

PMID:
29139564
20.

Sensory-mechanical effects of a dual bronchodilator and its anticholinergic component in COPD.

O'Donnell DE, Elbehairy AF, Faisal A, Neder JA, Webb KA; Canadian Respiratory Research Network (CRRN).

Respir Physiol Neurobiol. 2018 Jan;247:116-125. doi: 10.1016/j.resp.2017.10.001. Epub 2017 Oct 7.

PMID:
28993264
21.

CT imaging of chronic obstructive pulmonary disease: insights, disappointments, and promise.

Washko GR, Coxson HO, O'Donnell DE, Aaron SD.

Lancet Respir Med. 2017 Nov;5(11):903-908. doi: 10.1016/S2213-2600(17)30345-4. Epub 2017 Sep 28.

PMID:
28965820
22.

Work productivity loss in mild to moderate COPD: lessons learned from the CanCOLD study.

de Sousa Sena R, Ahmed S, Tan WC, Li PZ, Labonté L, Aaron SD, Benedetti A, Chapman KR, Walker B, Fitzgerald JM, Hernandez P, Maltais F, Marciniuk DD, O'Donnell DE, Sin DD, Bourbeau J; CanCOLD Collaborative Research Group and The Canadian Respiratory Research Network.

Eur Respir J. 2017 Sep 12;50(3). pii: 1701154. doi: 10.1183/13993003.01154-2017. Print 2017 Sep. No abstract available.

PMID:
28899939
23.

Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study.

Kirby M, Tanabe N, Tan WC, Zhou G, Obeidat M, Hague CJ, Leipsic J, Bourbeau J, Sin DD, Hogg JC, Coxson HO; CanCOLD Collaborative Research Group; Canadian Respiratory Research Network; CanCOLD Collaborative Research Group, the Canadian Respiratory Research Network.

Am J Respir Crit Care Med. 2018 Jan 1;197(1):56-65. doi: 10.1164/rccm.201704-0692OC.

PMID:
28886252
24.

Impact of LABA/LAMA combination on exercise endurance and lung hyperinflation in COPD: A pair-wise and network meta-analysis.

Calzetta L, Ora J, Cavalli F, Rogliani P, O'Donnell DE, Cazzola M.

Respir Med. 2017 Aug;129:189-198. doi: 10.1016/j.rmed.2017.06.020. Epub 2017 Jun 29. Review.

PMID:
28732830
25.

Excess Ventilation in Chronic Obstructive Pulmonary Disease-Heart Failure Overlap. Implications for Dyspnea and Exercise Intolerance.

Rocha A, Arbex FF, Sperandio PA, Souza A, Biazzim L, Mancuso F, Berton DC, Hochhegger B, Alencar MCN, Nery LE, O'Donnell DE, Neder JA.

Am J Respir Crit Care Med. 2017 Nov 15;196(10):1264-1274. doi: 10.1164/rccm.201704-0675OC.

PMID:
28665692
26.

Adverse cardiac events associated with incident opioid drug use among older adults with COPD.

Vozoris NT, Wang X, Austin PC, Lee DS, Stephenson AL, O'Donnell DE, Gill SS, Rochon PA.

Eur J Clin Pharmacol. 2017 Oct;73(10):1287-1295. doi: 10.1007/s00228-017-2278-3. Epub 2017 Jun 29.

PMID:
28664359
27.

Mild chronic obstructive pulmonary disease: why spirometry is not sufficient!

Elbehairy AF, Parraga G, Webb KA, Neder JA, O'Donnell DE; Canadian Respiratory Research Network (CRRN).

Expert Rev Respir Med. 2017 Jul;11(7):549-563. doi: 10.1080/17476348.2017.1334553. Epub 2017 Jun 5.

PMID:
28548545
28.

Long-term safety and efficacy of glycopyrrolate/formoterol metered dose inhaler using novel Co-Suspension™ Delivery Technology in patients with chronic obstructive pulmonary disease.

Hanania NA, Tashkin DP, Kerwin EM, Donohue JF, Denenberg M, O'Donnell DE, Quinn D, Siddiqui S, Orevillo C, Maes A, Reisner C.

Respir Med. 2017 May;126:105-115. doi: 10.1016/j.rmed.2017.03.015. Epub 2017 Mar 12.

29.

Effects of combined tiotropium/olodaterol on inspiratory capacity and exercise endurance in COPD.

O'Donnell DE, Casaburi R, Frith P, Kirsten A, De Sousa D, Hamilton A, Xue W, Maltais F.

Eur Respir J. 2017 Apr 19;49(4). pii: 1601348. doi: 10.1183/13993003.01348-2016. Print 2017 Apr.

30.

The Link between Reduced Inspiratory Capacity and Exercise Intolerance in Chronic Obstructive Pulmonary Disease.

O'Donnell DE, Elbehairy AF, Webb KA, Neder JA; Canadian Respiratory Research Network.

Ann Am Thorac Soc. 2017 Jul;14(Supplement_1):S30-S39. doi: 10.1513/AnnalsATS.201610-834FR. Review.

PMID:
28398073
31.

Resting Physiological Correlates of Reduced Exercise Capacity in Smokers with Mild Airway Obstruction.

Elbehairy AF, Faisal A, Guenette JA, Jensen D, Webb KA, Ahmed R, Neder JA, O'Donnell DE; Canadian Respiratory Research Network (CRRN).

COPD. 2017 Jun;14(3):267-275. doi: 10.1080/15412555.2017.1281901. Epub 2017 Apr 3.

PMID:
28368706
32.

Ventilatory Inefficiency and Exertional Dyspnea in Early Chronic Obstructive Pulmonary Disease.

Neder JA, Berton DC, Müller PT, Elbehairy AF, Rocha A, Palange P, O'Donnell DE; Canadian Respiratory Research Network.

Ann Am Thorac Soc. 2017 Jul;14(Supplement_1):S22-S29. doi: 10.1513/AnnalsATS.201612-1033FR. Review.

PMID:
28345959
33.

Advances in the Evaluation of Respiratory Pathophysiology during Exercise in Chronic Lung Diseases.

O'Donnell DE, Elbehairy AF, Berton DC, Domnik NJ, Neder JA.

Front Physiol. 2017 Feb 22;8:82. doi: 10.3389/fphys.2017.00082. eCollection 2017. Review.

34.

Incident opioid use is associated with risk of respiratory harm in non-palliative COPD.

Vozoris NT, O'Donnell DE, Bell C, Gill SS, Rochon PA.

Eur Respir J. 2017 Mar 8;49(3). pii: 1602529. doi: 10.1183/13993003.02529-2016. Print 2017 Mar. No abstract available.

35.

Impaired exercise ventilatory efficiency in smokers with low transfer factor but normal spirometry.

Walter Barbosa G, Neder JA, Utida K, O'Donnell DE, de Tarso Müller P.

Eur Respir J. 2017 Mar 8;49(3). pii: 1602511. doi: 10.1183/13993003.02511-2016. Print 2017 Mar. No abstract available.

36.

Physiological and clinical relevance of exercise ventilatory efficiency in COPD.

Neder JA, Berton DC, Arbex FF, Alencar MC, Rocha A, Sperandio PA, Palange P, O'Donnell DE.

Eur Respir J. 2017 Mar 8;49(3). pii: 1602036. doi: 10.1183/13993003.02036-2016. Print 2017 Mar. Review.

37.

Oral N-acetylcysteine and exercise tolerance in mild chronic obstructive pulmonary disease.

Hirai DM, Jones JH, Zelt JT, da Silva ML, Bentley RF, Edgett BA, Gurd BJ, Tschakovsky ME, O'Donnell DE, Neder JA.

J Appl Physiol (1985). 2017 May 1;122(5):1351-1361. doi: 10.1152/japplphysiol.00990.2016. Epub 2017 Mar 2.

38.

Emphysema on Thoracic CT and Exercise Ventilatory Inefficiency in Mild-to-Moderate COPD.

Jones JH, Zelt JT, Hirai DM, Diniz CV, Zaza A, O'Donnell DE, Neder JA.

COPD. 2017 Apr;14(2):210-218. doi: 10.1080/15412555.2016.1253670. Epub 2016 Dec 20.

PMID:
27997255
39.

Maximal Inspiratory Pressure: Does the Choice of Reference Values Actually Matter?

Rodrigues A, Da Silva ML, Berton DC, Cipriano G Jr, Pitta F, O'Donnell DE, Neder JA.

Chest. 2017 Jul;152(1):32-39. doi: 10.1016/j.chest.2016.11.045. Epub 2016 Dec 8.

PMID:
27940276
40.

Opioids and adverse outcomes in elderly chronic obstructive pulmonary disease patients.

Vozoris NT, O'Donnell DE, Gill SS.

Eur Respir J. 2016 Dec;48(6):1818. doi: 10.1183/13993003.01690-2016. No abstract available.

41.

Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study.

Tan WC, Hague CJ, Leipsic J, Bourbeau J, Zheng L, Li PZ, Sin DD, Coxson HO, Kirby M, Hogg JC, Raju R, Road J, O'Donnell DE, Maltais F, Hernandez P, Cowie R, Chapman KR, Marciniuk DD, FitzGerald JM, Aaron SD; Canadian Respiratory Research Network and the CanCOLD Collaborative Research group.

PLoS One. 2016 Nov 18;11(11):e0166745. doi: 10.1371/journal.pone.0166745. eCollection 2016.

42.

Influence of heart failure on resting lung volumes in patients with COPD.

Souza AS, Sperandio PA, Mazzuco A, Alencar MC, Arbex FF, Oliveira MF, O'Donnell DE, Neder JA.

J Bras Pneumol. 2016 Jul-Aug;42(4):273-278. doi: 10.1590/S1806-37562015000000290. English, Portuguese.

43.

Chronic breathlessness in patients with idiopathic pulmonary fibrosis: a major challenge for caregivers.

O'Donnell DE, Neder JA, Harle I, Moran-Mendoza O.

Expert Rev Respir Med. 2016 Dec;10(12):1295-1303. Epub 2016 Nov 2. Review.

PMID:
27766905
44.

Opioids in COPD: a cause of death or a marker of illness severity?

Vozoris NT, O'Donnell DE, Bell CM, Gill SS, Rochon PA.

Eur Respir J. 2016 Nov;48(5):1521-1522. doi: 10.1183/13993003.01573-2016. No abstract available.

45.

Dietary nitrate supplementation and exercise tolerance in patients with heart failure with reduced ejection fraction.

Hirai DM, Zelt JT, Jones JH, Castanhas LG, Bentley RF, Earle W, Staples P, Tschakovsky ME, McCans J, O'Donnell DE, Neder JA.

Am J Physiol Regul Integr Comp Physiol. 2017 Jan 1;312(1):R13-R22. doi: 10.1152/ajpregu.00263.2016. Epub 2016 Oct 26.

46.

Physiological and sensory consequences of exercise oscillatory ventilation in heart failure-COPD.

Rocha A, Arbex FF, Alencar MC, Sperandio PA, Hirai DM, Berton DC, O'Donnell DE, Neder JA.

Int J Cardiol. 2016 Dec 1;224:447-453. doi: 10.1016/j.ijcard.2016.09.077. Epub 2016 Sep 24.

PMID:
27701063
47.

Different dyspnoea perception in COPD patients with frequent and infrequent exacerbations.

Scioscia G, Blanco I, Arismendi E, Burgos F, Gistau C, Foschino Barbaro MP, Celli B, O'Donnell DE, Agustí A.

Thorax. 2017 Feb;72(2):117-121. doi: 10.1136/thoraxjnl-2016-208332. Epub 2016 Sep 1.

PMID:
27586869
48.

Exertional dyspnoea in COPD: the clinical utility of cardiopulmonary exercise testing.

O'Donnell DE, Elbehairy AF, Faisal A, Webb KA, Neder JA, Mahler DA.

Eur Respir Rev. 2016 Sep;25(141):333-47. doi: 10.1183/16000617.0054-2016. Review. Erratum in: Eur Respir Rev. 2016 Dec;25(142):513.

49.

Mechanisms of exertional dyspnoea in symptomatic smokers without COPD.

Elbehairy AF, Guenette JA, Faisal A, Ciavaglia CE, Webb KA, Jensen D, Ramsook AH, Neder JA, O'Donnell DE; Canadian Respiratory Research Network.

Eur Respir J. 2016 Sep;48(3):694-705. doi: 10.1183/13993003.00077-2016. Epub 2016 Aug 4.

50.

Update on Nonsurgical Lung Volume Reduction Procedures.

Neder JA, O'Donnell DE.

Can Respir J. 2016;2016:6462352. doi: 10.1155/2016/6462352. Epub 2016 May 17. Review.

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