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Items: 29


Author Correction: Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.

Wong GS, Zhou J, Bin Liu J, Wu Z, Xu X, Li T, Xu D, Schumacher SE, Puschhof J, McFarland J, Zou C, Dulak A, Henderson L, Xu P, O'Day E, Rendak R, Liao WL, Cecchi F, Hembrough T, Schwartz S, Szeto C, Rustgi AK, Wong KK, Diehl JA, Jensen K, Graziano F, Ruzzo A, Fereshetian S, Mertins P, Carr SA, Beroukhim R, Nakamura K, Oki E, Watanabe M, Baba H, Imamura Y, Catenacci D, Bass AJ.

Nat Med. 2018 Oct;24(10):1627. doi: 10.1038/s41591-018-0168-6.


Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.

Wong GS, Zhou J, Liu JB, Wu Z, Xu X, Li T, Xu D, Schumacher SE, Puschhof J, McFarland J, Zou C, Dulak A, Henderson L, Xu P, O'Day E, Rendak R, Liao WL, Cecchi F, Hembrough T, Schwartz S, Szeto C, Rustgi AK, Wong KK, Diehl JA, Jensen K, Graziano F, Ruzzo A, Fereshetian S, Mertins P, Carr SA, Beroukhim R, Nakamura K, Oki E, Watanabe M, Baba H, Imamura Y, Catenacci D, Bass AJ.

Nat Med. 2018 Jul;24(7):968-977. doi: 10.1038/s41591-018-0022-x. Epub 2018 May 28. Erratum in: Nat Med. 2018 Oct;24(10):1627.


Are We There Yet? How and When Specific Biotechnologies Will Improve Human Health.

O'Day E, Hosta-Rigau L, Oyarzún DA, Okano H, de Lorenzo V, von Kameke C, Alsafar H, Cao C, Chen GQ, Ji W, Roberts RJ, Ronaghi M, Yeung K, Zhang F, Lee SY.

Biotechnol J. 2018 May 24:e1800195. doi: 10.1002/biot.201800195. [Epub ahead of print] Review.


The power of synthetic biology for bioproduction, remediation and pollution control: The UN's Sustainable Development Goals will inevitably require the application of molecular biology and biotechnology on a global scale.

de Lorenzo V, Prather KL, Chen GQ, O'Day E, von Kameke C, Oyarzún DA, Hosta-Rigau L, Alsafar H, Cao C, Ji W, Okano H, Roberts RJ, Ronaghi M, Yeung K, Zhang F, Lee SY.

EMBO Rep. 2018 Apr;19(4). pii: e45658. doi: 10.15252/embr.201745658. Epub 2018 Mar 26. No abstract available.


Targeted Therapies for Targeted Populations: Anti-EGFR Treatment for EGFR-Amplified Gastroesophageal Adenocarcinoma.

Maron SB, Alpert L, Kwak HA, Lomnicki S, Chase L, Xu D, O'Day E, Nagy RJ, Lanman RB, Cecchi F, Hembrough T, Schrock A, Hart J, Xiao SY, Setia N, Catenacci DVT.

Cancer Discov. 2018 Jun;8(6):696-713. doi: 10.1158/2159-8290.CD-17-1260. Epub 2018 Feb 15.


Associations between feelings of social anxiety and emotion perception.

Lynn SK, Bui E, Hoeppner SS, O'Day EB, Palitz SA, Barrett LF, Simon NM.

J Behav Ther Exp Psychiatry. 2018 Jun;59:40-47. doi: 10.1016/j.jbtep.2017.10.001. Epub 2017 Oct 4.


Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma.

Pectasides E, Stachler MD, Derks S, Liu Y, Maron S, Islam M, Alpert L, Kwak H, Kindler H, Polite B, Sharma MR, Allen K, O'Day E, Lomnicki S, Maranto M, Kanteti R, Fitzpatrick C, Weber C, Setia N, Xiao SY, Hart J, Nagy RJ, Kim KM, Choi MG, Min BH, Nason KS, O'Keefe L, Watanabe M, Baba H, Lanman R, Agoston AT, Oh DJ, Dunford A, Thorner AR, Ducar MD, Wollison BM, Coleman HA, Ji Y, Posner MC, Roggin K, Turaga K, Chang P, Hogarth K, Siddiqui U, Gelrud A, Ha G, Freeman SS, Rhoades J, Reed S, Gydush G, Rotem D, Davison J, Imamura Y, Adalsteinsson V, Lee J, Bass AJ, Catenacci DV.

Cancer Discov. 2018 Jan;8(1):37-48. doi: 10.1158/2159-8290.CD-17-0395. Epub 2017 Oct 4.


The loss of a fellow service member: Complicated grief in post-9/11 service members and veterans with combat-related posttraumatic stress disorder.

Simon NM, O'Day EB, Hellberg SN, Hoeppner SS, Charney ME, Robinaugh DJ, Bui E, Goetter EM, Baker AW, Rogers AH, Nadal-Vicens M, Venners MR, Kim HM, Rauch SAM.

J Neurosci Res. 2018 Jan;96(1):5-15. doi: 10.1002/jnr.24094. Epub 2017 Jun 13.


Outcomes From Pediatric Gastroenterology Maintenance of Certification Using Web-based Modules.

Sheu J, Chun S, O'Day E, Cheung S, Cruz R, Lightdale JR, Fishman DS, Bousvaros A, Huang JS.

J Pediatr Gastroenterol Nutr. 2017 May;64(5):671-678. doi: 10.1097/MPG.0000000000001488.


MET tyrosine kinase receptor expression and amplification as prognostic biomarkers of survival in gastroesophageal adenocarcinoma.

Catenacci DV, Ang A, Liao WL, Shen J, O'Day E, Loberg RD, Cecchi F, Hembrough T, Ruzzo A, Graziano F.

Cancer. 2017 May 15;123(6):1061-1070. doi: 10.1002/cncr.30437. Epub 2016 Dec 7.


Lifting and exertion injuries decrease after implementation of an integrated hospital-wide safe patient handling and mobilisation programme.

Dennerlein JT, O'Day ET, Mulloy DF, Somerville J, Stoddard AM, Kenwood C, Teeple E, Boden LI, Sorensen G, Hashimoto D.

Occup Environ Med. 2017 May;74(5):336-343. doi: 10.1136/oemed-2015-103507. Epub 2016 Oct 25.


Therapeutically Induced Changes in HER2, HER3, and EGFR Protein Expression for Treatment Guidance.

Sellappan S, Blackler A, Liao WL, O'Day E, Xu P, Thyparambil S, Cecchi F, Hembrough T, Catenacci DV.

J Natl Compr Canc Netw. 2016 May;14(5):503-7.


Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and FISH.

Catenacci DV, Liao WL, Zhao L, Whitcomb E, Henderson L, O'Day E, Xu P, Thyparambil S, Krizman D, Bengali K, Uzzell J, Darfler M, Cecchi F, Blackler A, Bang YJ, Hart J, Xiao SY, Lee SM, Burrows J, Hembrough T.

Gastric Cancer. 2016 Oct;19(4):1066-79. doi: 10.1007/s10120-015-0566-0. Epub 2015 Nov 18.


An RNA-binding Protein, Lin28, Recognizes and Remodels G-quartets in the MicroRNAs (miRNAs) and mRNAs It Regulates.

O'Day E, Le MT, Imai S, Tan SM, Kirchner R, Arthanari H, Hofmann O, Wagner G, Lieberman J.

J Biol Chem. 2015 Jul 17;290(29):17909-22. doi: 10.1074/jbc.M115.665521. Epub 2015 Jun 4.


G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments.

Ivanov P, O'Day E, Emara MM, Wagner G, Lieberman J, Anderson P.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18201-6. doi: 10.1073/pnas.1407361111. Epub 2014 Nov 17.


Worker assessments of organizational practices and psychosocial work environment are associated with musculoskeletal injuries in hospital patient care workers.

Reme SE, Shaw WS, Boden LI, Tveito TH, O'Day ET, Dennerlein JT, Sorensen G.

Am J Ind Med. 2014 Jul;57(7):810-8. doi: 10.1002/ajim.22319. Epub 2014 Apr 15.


Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages.

Guilliams T, El-Turk F, Buell AK, O'Day EM, Aprile FA, Esbjörner EK, Vendruscolo M, Cremades N, Pardon E, Wyns L, Welland ME, Steyaert J, Christodoulou J, Dobson CM, De Genst E.

J Mol Biol. 2013 Jul 24;425(14):2397-411. doi: 10.1016/j.jmb.2013.01.040. Epub 2013 Apr 1.


Psychosocial stress and multi-site musculoskeletal pain: a cross-sectional survey of patient care workers.

Sembajwe G, Tveito TH, Hopcia K, Kenwood C, O'Day ET, Stoddard AM, Dennerlein JT, Hashimoto D, Sorensen G.

Workplace Health Saf. 2013 Mar;61(3):117-25. doi: 10.3928/21650799-20130226-01.


The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β.

Luna RE, Arthanari H, Hiraishi H, Nanda J, Martin-Marcos P, Markus MA, Akabayov B, Milbradt AG, Luna LE, Seo HC, Hyberts SG, Fahmy A, Reibarkh M, Miles D, Hagner PR, O'Day EM, Yi T, Marintchev A, Hinnebusch AG, Lorsch JR, Asano K, Wagner G.

Cell Rep. 2012 Jun 28;1(6):689-702. doi: 10.1016/j.celrep.2012.04.007. Epub 2012 May 24.


Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling.

Lal A, Thomas MP, Altschuler G, Navarro F, O'Day E, Li XL, Concepcion C, Han YC, Thiery J, Rajani DK, Deutsch A, Hofmann O, Ventura A, Hide W, Lieberman J.

PLoS Genet. 2011 Nov;7(11):e1002363. doi: 10.1371/journal.pgen.1002363. Epub 2011 Nov 10.


Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs.

Le MT, Shyh-Chang N, Khaw SL, Chin L, Teh C, Tay J, O'Day E, Korzh V, Yang H, Lal A, Lieberman J, Lodish HF, Lim B.

PLoS Genet. 2011 Sep;7(9):e1002242. doi: 10.1371/journal.pgen.1002242. Epub 2011 Sep 15.


HIV DNA is heavily uracilated, which protects it from autointegration.

Yan N, O'Day E, Wheeler LA, Engelman A, Lieberman J.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9244-9. doi: 10.1073/pnas.1102943108. Epub 2011 May 16.


Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.

De Genst EJ, Guilliams T, Wellens J, O'Day EM, Waudby CA, Meehan S, Dumoulin M, Hsu ST, Cremades N, Verschueren KH, Pardon E, Wyns L, Steyaert J, Christodoulou J, Dobson CM.

J Mol Biol. 2010 Sep 17;402(2):326-43. doi: 10.1016/j.jmb.2010.07.001. Epub 2010 Jul 8.


MicroRNAs and their target gene networks in breast cancer.

O'Day E, Lal A.

Breast Cancer Res. 2010;12(2):201. doi: 10.1186/bcr2484. Epub 2010 Mar 19. Review.


(1)H, (13)C and (15)N assignments of a camelid nanobody directed against human alpha-synuclein.

Vuchelen A, O'Day E, De Genst E, Pardon E, Wyns L, Dumoulin M, Dobson CM, Christodoulou J, Hsu ST.

Biomol NMR Assign. 2009 Dec;3(2):231-3. doi: 10.1007/s12104-009-9182-4.


miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements.

Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O'Day E, Chowdhury D, Dykxhoorn DM, Tsai P, Hofmann O, Becker KG, Gorospe M, Hide W, Lieberman J.

Mol Cell. 2009 Sep 11;35(5):610-25. doi: 10.1016/j.molcel.2009.08.020.


Time evolution of the quaternary structure of Escherichia coli aspartate transcarbamoylase upon reaction with the natural substrates and a slow, tight-binding inhibitor.

West JM, Xia J, Tsuruta H, Guo W, O'Day EM, Kantrowitz ER.

J Mol Biol. 2008 Dec 5;384(1):206-18. doi: 10.1016/j.jmb.2008.09.022. Epub 2008 Sep 16.


Use of L-asparagine and N-phosphonacetyl-L-asparagine to investigate the linkage of catalysis and homotropic cooperativity in E. coli aspartate transcarbomoylase.

Cardia JP, Eldo J, Xia J, O'Day EM, Tsuruta H, Gryncel KR, Kantrowitz ER.

Proteins. 2008 May 15;71(3):1088-96.


N-phosphonacetyl-L-isoasparagine a potent and specific inhibitor of Escherichia coli aspartate transcarbamoylase.

Eldo J, Cardia JP, O'Day EM, Xia J, Tsuruta H, Kantrowitz ER.

J Med Chem. 2006 Oct 5;49(20):5932-8.

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