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Items: 1 to 50 of 52

1.

Anterior segment infiltration of acute lymphoblastic leukemia: case report and systematic review.

Yu AM, Chan SC, Iordanous Y, Padmore RF, O'Connor MD.

Can J Ophthalmol. 2019 Feb;54(1):20-26. doi: 10.1016/j.jcjo.2018.02.016. Epub 2018 Apr 22. Review.

PMID:
30851770
2.

Stems cells, big data and compendium-based analyses for identifying cell types, signalling pathways and gene regulatory networks.

Kabir MH, O'Connor MD.

Biophys Rev. 2019 Feb;11(1):41-50. doi: 10.1007/s12551-018-0486-4. Epub 2019 Jan 25. Review.

3.

Identification of active signaling pathways by integrating gene expression and protein interaction data.

Kabir MH, Patrick R, Ho JWK, O'Connor MD.

BMC Syst Biol. 2018 Dec 31;12(Suppl 9):120. doi: 10.1186/s12918-018-0655-x.

4.

C3: An R package for cross-species compendium-based cell-type identification.

Kabir MH, Djordjevic D, O'Connor MD, Ho JWK.

Comput Biol Chem. 2018 Dec;77:187-192. doi: 10.1016/j.compbiolchem.2018.10.003. Epub 2018 Oct 9.

PMID:
30340080
5.

Light-focusing human micro-lenses generated from pluripotent stem cells model lens development and drug-induced cataract in vitro.

Murphy P, Kabir MH, Srivastava T, Mason ME, Dewi CU, Lim S, Yang A, Djordjevic D, Killingsworth MC, Ho JWK, Harman DG, O'Connor MD.

Development. 2018 Jan 9;145(1). pii: dev155838. doi: 10.1242/dev.155838.

6.

The Potential for Gut Organoid Derived Interstitial Cells of Cajal in Replacement Therapy.

Zhou J, O'Connor MD, Ho V.

Int J Mol Sci. 2017 Sep 26;18(10). pii: E2059. doi: 10.3390/ijms18102059. Review.

7.

Capillary Electrophoresis to Monitor Peptide Grafting onto Chitosan Films in Real Time.

Thevarajah JJ, O'Connor MD, Castignolles P, Gaborieau M.

J Vis Exp. 2016 Oct 26;(116). doi: 10.3791/54549.

8.

Trends in subspecialty training by Canadian ophthalmology graduates.

Sivachandran N, Noble J, Dollin M, O'Connor MD, Gupta RR.

Can J Ophthalmol. 2016 Jun;51(3):201-6. doi: 10.1016/j.jcjo.2015.10.011. Epub 2016 May 11.

PMID:
27316270
9.

Traumatic carotid cavernous fistula in a pediatric patient.

Yang Y, Kapasi M, Abdeen N, Dos Santos MP, O'Connor MD.

Can J Ophthalmol. 2015 Aug;50(4):318-21. doi: 10.1016/j.jcjo.2015.05.014. No abstract available.

PMID:
26257228
10.

Real-time monitoring of peptide grafting onto chitosan films using capillary electrophoresis.

Taylor DL, Thevarajah JJ, Narayan DK, Murphy P, Mangala MM, Lim S, Wuhrer R, Lefay C, O'Connor MD, Gaborieau M, Castignolles P.

Anal Bioanal Chem. 2015 Mar;407(9):2543-55. doi: 10.1007/s00216-015-8483-y. Epub 2015 Feb 14.

PMID:
25680633
11.

Managing the potential and pitfalls during clinical translation of emerging stem cell therapies.

Main H, Munsie M, O'Connor MD.

Clin Transl Med. 2014 May 9;3:10. doi: 10.1186/2001-1326-3-10. eCollection 2014. Review.

12.

A human embryonic stem cell line adapted for high throughput screening.

Caron NJ, Gage BK, O'Connor MD, Eaves CJ, Kieffer TJ, Piret JM.

Biotechnol Bioeng. 2013 Oct;110(10):2706-16. doi: 10.1002/bit.24936. Epub 2013 Apr 29.

PMID:
23613129
13.

The 3R principle: advancing clinical application of human pluripotent stem cells.

O'Connor MD.

Stem Cell Res Ther. 2013 Mar 8;4(2):21. doi: 10.1186/scrt169. Review.

14.

An unusual corneal limbal foreign body: Ostracoda shell.

Dollin M, Jastrzebski A, Bhatti A, Graham L, O'Connor MD, Brownstein S.

Can J Ophthalmol. 2012 Dec;47(6):e49. doi: 10.1016/j.jcjo.2012.04.019. Epub 2012 Sep 25. No abstract available.

PMID:
23217516
15.

Brachial artery occlusion in a young adult with an ACTA2 thoracic aortic aneurysm.

Al-Mohaissen M, Allanson JE, O'Connor MD, Veinot JP, Brandys TM, Maharajh G, Dennie CJ, Beauchesne LM.

Vasc Med. 2012 Oct;17(5):326-9. doi: 10.1177/1358863X12453973. Epub 2012 Sep 3.

PMID:
22946110
16.

Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer's disease.

Ooi L, Sidhu K, Poljak A, Sutherland G, O'Connor MD, Sachdev P, Münch G.

J Neural Transm (Vienna). 2013 Jan;120(1):103-11. doi: 10.1007/s00702-012-0839-2. Epub 2012 Jun 13. Review.

PMID:
22695755
17.

Pediatric cataracts: hitting the target refraction is not the problem, it's knowing where to aim.

O'Connor MD.

Can J Ophthalmol. 2011 Apr;46(2):125-7. doi: 10.3129/i11-010. English, French. No abstract available.

PMID:
21708078
18.

Retinoblastoma-binding proteins 4 and 9 are important for human pluripotent stem cell maintenance.

O'Connor MD, Wederell E, Robertson G, Delaney A, Morozova O, Poon SS, Yap D, Fee J, Zhao Y, McDonald H, Zeng T, Hirst M, Marra MA, Aparicio SA, Eaves CJ.

Exp Hematol. 2011 Aug;39(8):866-79.e1. doi: 10.1016/j.exphem.2011.05.008. Epub 2011 May 27.

19.

Functional assays for human embryonic stem cell pluripotency.

O'Connor MD, Kardel MD, Eaves CJ.

Methods Mol Biol. 2011;690:67-80. doi: 10.1007/978-1-60761-962-8_4.

PMID:
21042985
20.

PEG-PLA microparticles for encapsulation and delivery of Tat-EGFP to retinal cells.

Rafat M, Cléroux CA, Fong WG, Baker AN, Leonard BC, O'Connor MD, Tsilfidis C.

Biomaterials. 2010 Apr;31(12):3414-21. doi: 10.1016/j.biomaterials.2010.01.031. Epub 2010 Feb 9.

PMID:
20149443
21.

Enhanced generation of hematopoietic cells from human hepatocarcinoma cell-stimulated human embryonic and induced pluripotent stem cells.

Lu M, Kardel MD, O'Connor MD, Eaves CJ.

Exp Hematol. 2009 Aug;37(8):924-36. doi: 10.1016/j.exphem.2009.05.007. Epub 2009 May 27.

PMID:
19481135
22.

Homozygous contiguous gene deletion of 13q12 causing LGMD2C and ARSACS in the same patient.

McMillan HJ, Carter MT, Jacob PJ, Laffan EE, O'Connor MD, Boycott KM.

Muscle Nerve. 2009 Mar;39(3):396-9. doi: 10.1002/mus.21222.

PMID:
19208398
23.

Resurrection of the bell-ringer.

Gupta RR, O'Connor MD, Hurley BR.

Can J Ophthalmol. 2008 Oct;43(5):600. doi: 10.3129/i08-134. No abstract available.

PMID:
18982042
24.

Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks.

Bañuelos CA, Banáth JP, MacPhail SH, Zhao J, Eaves CA, O'Connor MD, Lansdorp PM, Olive PL.

DNA Repair (Amst). 2008 Sep 1;7(9):1471-83. doi: 10.1016/j.dnarep.2008.05.005. Epub 2008 Jul 3.

PMID:
18602349
25.

Generation of transparency and cellular organization in lens explants.

O'Connor MD, Wederell ED, de Iongh R, Lovicu FJ, McAvoy JW.

Exp Eye Res. 2008 May;86(5):734-45. doi: 10.1016/j.exer.2008.01.020. Epub 2008 Feb 3.

PMID:
18343368
26.

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells.

Morin RD, O'Connor MD, Griffith M, Kuchenbauer F, Delaney A, Prabhu AL, Zhao Y, McDonald H, Zeng T, Hirst M, Eaves CJ, Marra MA.

Genome Res. 2008 Apr;18(4):610-21. doi: 10.1101/gr.7179508. Epub 2008 Feb 19. Erratum in: Genome Res. 2009 May;19(5):958.

27.

Alkaline phosphatase-positive colony formation is a sensitive, specific, and quantitative indicator of undifferentiated human embryonic stem cells.

O'Connor MD, Kardel MD, Iosfina I, Youssef D, Lu M, Li MM, Vercauteren S, Nagy A, Eaves CJ.

Stem Cells. 2008 May;26(5):1109-16. doi: 10.1634/stemcells.2007-0801. Epub 2008 Feb 14.

28.

Histopathology in a dissecting conjunctival filtering bleb.

O'Connor MD, Talbot R, Brownstein S, Rawlings N, Damji KF.

Can J Ophthalmol. 2008 Feb;43(1):114-5. doi: 10.3129/i07-209.

PMID:
18204492
29.

LongSAGE profiling of nine human embryonic stem cell lines.

Hirst M, Delaney A, Rogers SA, Schnerch A, Persaud DR, O'Connor MD, Zeng T, Moksa M, Fichter K, Mah D, Go A, Morin RD, Baross A, Zhao Y, Khattra J, Prabhu AL, Pandoh P, McDonald H, Asano J, Dhalla N, Ma K, Lee S, Ally A, Chahal N, Menzies S, Siddiqui A, Holt R, Jones S, Gerhard DS, Thomson JA, Eaves CJ, Marra MA.

Genome Biol. 2007;8(6):R113.

30.

In vitro generation of functional lens-like structures with relevance to age-related nuclear cataract.

O'Connor MD, McAvoy JW.

Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1245-52.

PMID:
17325169
31.

Multiple bilateral primary cysts of the iris pigment epithelium.

O'Connor MD, Kertes PJ, Sheikh A.

Can J Ophthalmol. 2006 Dec;41(6):761-2.

PMID:
17224960
32.

What not to wear.

O'Connor MD.

CMAJ. 2005 Dec 6;173(12):1493. No abstract available.

33.

Respiratory and metabolic effects of decreased osmolality in conscious rats.

O'Connor MD, Jennings DB.

Can J Physiol Pharmacol. 2001 Sep;79(9):768-78.

PMID:
11599777
34.

Tissue plasminogen activator for treatment of fibrin in endophthalmitis.

Damji KF, O'Connor MD, Hill V.

Can J Ophthalmol. 2001 Aug;36(5):269-71. No abstract available.

PMID:
11548143
35.

Patient education: designing a state-of-the-art consumer health information library.

Pittman TJ, O'Connor MD, Millar S, Erickson JI.

J Nurs Adm. 2001 Jun;31(6):316-23.

PMID:
11417171
36.

Granzymes: a variety of serine protease specificities encoded by genetically distinct subfamilies.

Smyth MJ, O'Connor MD, Trapani JA.

J Leukoc Biol. 1996 Nov;60(5):555-62. Review.

PMID:
8929545
37.

A novel substrate-binding pocket interaction restricts the specificity of the human NK cell-specific serine protease, Met-ase-1.

Smyth MJ, O'Connor MD, Trapani JA, Kershaw MH, Brinkworth RI.

J Immunol. 1996 Jun 1;156(11):4174-81.

PMID:
8666785
38.

Cloning and expression of a second human natural killer cell granule tryptase, HNK-Tryp-2/granzyme 3.

Sayers TJ, Lloyd AR, McVicar DW, O'Connor MD, Kelly JM, Carter CR, Wiltrout TA, Wiltrout RH, Smyth MJ.

J Leukoc Biol. 1996 May;59(5):763-8.

PMID:
8656064
39.

Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1.

Kelly JM, O'Connor MD, Hulett MD, Thia KY, Smyth MJ.

Immunogenetics. 1996;44(5):340-50.

PMID:
8781119
40.

Expression of recombinant human Met-ase-1: a NK cell-specific granzyme.

Smyth MJ, O'Connor MD, Kelly JM, Ganesvaran P, Thia KY, Trapani JA.

Biochem Biophys Res Commun. 1995 Dec 14;217(2):675-83.

PMID:
7503751
42.

Biochemical and biophysical characterization of insulin granules isolated from rat pancreatic islets by an iso-osmotic gradient.

Matthews EK, McKay DB, O'Connor MD, Borowitz JL.

Biochim Biophys Acta. 1982 Mar 15;715(1):80-9.

PMID:
7041989
43.

The interaction of phenformin and phlorizin with brush border membrane vesicles, phospholipid liposomes, and phospholipid liposomes containing brush border membrane protein.

Ferguson DR, Matthews EK, O'Connor MD, Schuz AD.

Biochem Pharmacol. 1981 Jun 15;30(12):1613-9. No abstract available.

PMID:
7271849
44.

Capacity for alternating sites cooperativity in catalysis by succinyl-coenzyme A synthetase.

Wolodko WT, O'Connor MD, Bridger WA.

Proc Natl Acad Sci U S A. 1981 Apr;78(4):2140-4.

45.

Comparison of storage- and signal-limited models of pancreatic insulin secretion.

O'Connor MD, Landahl H, Grodsky GM.

Am J Physiol. 1980 May;238(5):R378-89.

PMID:
6990796
46.

The effect of sonication upon monoamine oxidase-A and -B in the rat liver.

Fowler CJ, Callingham BA, O'Connor MD, Matthews EK.

Biochem Pharmacol. 1980 Apr 15;29(8):1185-8. No abstract available.

PMID:
7387734
47.

Membrane surface interactions involved in insulin secretion.

O'Connor MD, Matthews EK.

Horm Metab Res Suppl. 1980;Suppl 10:149-53.

PMID:
7005056
48.

Dynamic oscillations in the membrane potential of pancreatic islet cells.

Matthews EK, O'Connor MD.

J Exp Biol. 1979 Aug;81:75-91.

49.

Glucose-stimulated 45Calcium efflux from isolated rat pancreatic islets.

Frankel BJ, Imagawa WT, O'Connor MD, Lundquist I, Kromhout JA, Fanska RE, Grodsky GM.

J Clin Invest. 1978 Sep;62(3):525-31.

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